Published in Proc Natl Acad Sci U S A on April 23, 2002
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Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science (2011) 9.00
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Determining the architectures of macromolecular assemblies. Nature (2007) 4.94
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The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol Cell (2002) 3.99
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proc Natl Acad Sci U S A (2007) 3.92
Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell (2006) 3.87
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The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab (2011) 3.54
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Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. EMBO J (2007) 3.31
ABI5 acts downstream of ABI3 to execute an ABA-dependent growth arrest during germination. Plant J (2002) 3.28
Induction of autophagy in axonal dystrophy and degeneration. J Neurosci (2006) 3.28
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev (2004) 3.25
Orai1 and STIM1 are critical for breast tumor cell migration and metastasis. Cancer Cell (2009) 3.20
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science (2013) 3.02
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02
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Validating Stat3 in cancer therapy. Nat Med (2005) 2.96
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Virtual gating and nuclear transport: the hole picture. Trends Cell Biol (2003) 2.68
Comprehensive analysis of diverse ribonucleoprotein complexes. Nat Methods (2007) 2.55
ZINBA integrates local covariates with DNA-seq data to identify broad and narrow regions of enrichment, even within amplified genomic regions. Genome Biol (2011) 2.47
Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43
AMP-activated protein kinase functionally phosphorylates endothelial nitric oxide synthase Ser633. Circ Res (2009) 2.38
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. J Biol Chem (2004) 2.36
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Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell (2007) 2.25
The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation. Mol Cell (2012) 2.20
A Rac-cGMP signaling pathway. Cell (2007) 2.16
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Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet (2011) 2.13
Chromatin-bound Xenopus Dppa2 shapes the nucleus by locally inhibiting microtubule assembly. Dev Cell (2013) 2.09
Crystal structure of oligomeric β1-adrenergic G protein-coupled receptors in ligand-free basal state. Nat Struct Mol Biol (2013) 2.06
Structural bases of unphosphorylated STAT1 association and receptor binding. Mol Cell (2005) 2.05
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Tracking and elucidating alphavirus-host protein interactions. J Biol Chem (2006) 2.01
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Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. Proc Natl Acad Sci U S A (2005) 1.97
Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation. Proc Natl Acad Sci U S A (2006) 1.95
Proteomic and genomic characterization of chromatin complexes at a boundary. J Cell Biol (2005) 1.92
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Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature (2008) 1.89
I-DIRT, a general method for distinguishing between specific and nonspecific protein interactions. J Proteome Res (2005) 1.87
MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. Mol Cell (2005) 1.85
Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. Cell Host Microbe (2008) 1.85
A modular cross-linking approach for exploring protein interactions. J Am Chem Soc (2003) 1.85
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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells. Clin Cancer Res (2008) 1.80
Regulation of class switch recombination and somatic mutation by AID phosphorylation. J Exp Med (2008) 1.78
Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo. J Cell Biol (2006) 1.78
Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. J Virol (2010) 1.78
Identification of SMARCAL1 as a component of the DNA damage response. J Biol Chem (2009) 1.74
Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor. Mol Cell Proteomics (2009) 1.74
The effects of cardiopulmonary bypass on the number of cerebral microemboli and the incidence of cognitive dysfunction after coronary artery bypass graft surgery. Anesth Analg (2009) 1.74
seeQTL: a searchable database for human eQTLs. Bioinformatics (2011) 1.72
Synthesis, characterization and DNA-binding properties of a new cobalt(II) complex: Co(bbt)2Cl2. J Inorg Biochem (2005) 1.70
Preferential migration of regulatory T cells mediated by glioma-secreted chemokines can be blocked with chemotherapy. Cancer Immunol Immunother (2007) 1.70
Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3. Cancer Res (2006) 1.69
Long range allosteric control of cytoplasmic dynein ATPase activity by the stalk and C-terminal domains. J Biol Chem (2005) 1.68
Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle. Proc Natl Acad Sci U S A (2005) 1.68
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Association of sarcopenia with functional decline in community-dwelling elderly subjects in Japan. Geriatr Gerontol Int (2013) 1.67
Blocking IL-17A promotes the resolution of pulmonary inflammation and fibrosis via TGF-beta1-dependent and -independent mechanisms. J Immunol (2011) 1.65
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Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex. Proc Natl Acad Sci U S A (2007) 1.64
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Targeted proteomic study of the cyclin-Cdk module. Mol Cell (2004) 1.56
Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR. EMBO J (2006) 1.56
Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail. J Am Chem Soc (2003) 1.56
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A novel tracheobronchial reconstruction for right upper lung carcinoma involving the lower trachea: preliminary results. Ann Thorac Surg (2012) 1.54
Increase of success rate for women undergoing embryo transfer by transcutaneous electrical acupoint stimulation: a prospective randomized placebo-controlled study. Fertil Steril (2011) 1.54
Site-specific silencing of regulatory elements as a mechanism of X inactivation. Cell (2012) 1.54
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Analysis of protein phosphorylation by hypothesis-driven multiple-stage mass spectrometry. Anal Chem (2004) 1.52
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An Updated Meta-Analysis Comparing Artificial Cervical Disc Arthroplasty (CDA) Versus Anterior Cervical Discectomy and Fusion (ACDF) for the Treatment of Cervical Degenerative Disc Disease (CDDD). Spine (Phila Pa 1976) (2015) 1.51
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Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin. Endocrinology (2009) 1.49