Published in Cardiol Res Pract on October 31, 2011
The continuing challenges of translational research: clinician-scientists' perspective. Cardiol Res Pract (2012) 0.86
Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. Arthritis Res Ther (2013) 0.80
Oxidative Stress and Skin Fibrosis. Curr Pathobiol Rep (2014) 0.80
NADPH oxidase enzymes in skin fibrosis: molecular targets and therapeutic agents. Arch Dermatol Res (2013) 0.79
Oxidative damage and antioxidative therapy in systemic sclerosis. Mediators Inflamm (2014) 0.77
Cytokines in the immunopathology of systemic sclerosis. Semin Immunopathol (2015) 0.75
Role of redoximiRs in fibrogenesis. Redox Biol (2015) 0.75
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol (1996) 13.14
Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res (2000) 10.95
TGF-beta signaling and the fibrotic response. FASEB J (2004) 9.81
The myofibroblast: one function, multiple origins. Am J Pathol (2007) 8.64
Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence? Lancet (2004) 6.37
Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest (2007) 5.19
Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci U S A (1997) 4.74
Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis. N Engl J Med (2006) 4.46
Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Res (2006) 3.17
A polymorphism in the CTGF promoter region associated with systemic sclerosis. N Engl J Med (2007) 2.95
The transcription factor NRF2 protects against pulmonary fibrosis. FASEB J (2004) 2.43
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway. Arterioscler Thromb Vasc Biol (2004) 2.18
Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway. Arthritis Rheum (2001) 1.93
Pathogenesis of Raynaud's phenomenon. Rheumatology (Oxford) (2005) 1.88
Evidence for in vivo peroxynitrite production in human acute lung injury. Am J Respir Crit Care Med (1995) 1.84
Sequential dermal microvascular and perivascular changes in the development of scleroderma. J Pathol (1992) 1.81
Nitric oxide regulates transforming growth factor-beta signaling in endothelial cells. Circ Res (2005) 1.79
Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit. FASEB J (1989) 1.79
Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma. Am J Pathol (2004) 1.77
Gene expression profiling of NRF2-mediated protection against oxidative injury. Free Radic Biol Med (2005) 1.76
Nitric oxide and the regulation of gene expression. Trends Cell Biol (2001) 1.76
Mechanisms and consequences of fibrosis in systemic sclerosis. Nat Clin Pract Rheumatol (2006) 1.73
Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp Biol Med (Maywood) (2002) 1.70
Heme oxygenase-1: a novel drug target for atherosclerotic diseases? Circulation (2006) 1.66
S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase. Proc Natl Acad Sci U S A (2002) 1.64
NO modulates NADPH oxidase function via heme oxygenase-1 in human endothelial cells. Hypertension (2006) 1.61
Implications of the mechanisms of action of tea polyphenols as antioxidants in vitro for chemoprevention in humans. Proc Soc Exp Biol Med (1999) 1.60
NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium. Am J Physiol (1996) 1.58
Venodilation in Raynaud's disease. Lancet (1993) 1.54
New developments in fibroblast and myofibroblast biology: implications for fibrosis and scleroderma. Curr Rheumatol Rep (2007) 1.54
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress. Carcinogenesis (2001) 1.48
Nitric oxide and nitric oxide-generating compounds inhibit hepatocyte protein synthesis. FASEB J (1991) 1.48
Nitric oxide-generating compounds inhibit total protein and collagen synthesis in cultured vascular smooth muscle cells. Circ Res (1995) 1.42
Mechanisms of Raynaud's disease. Vasc Med (2005) 1.36
Endothelin, an endothelial-dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action. Arthritis Rheum (1991) 1.36
Endothelial cell apoptosis in systemic sclerosis is induced by antibody-dependent cell-mediated cytotoxicity via CD95. Arthritis Rheum (2000) 1.33
L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie's fibrotic plaque and related fibroblast cultures. Nitric Oxide (2003) 1.31
Contribution of activin receptor-like kinase 5 (transforming growth factor beta receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts. Arthritis Rheum (2006) 1.30
The basics about nitric oxide. Mol Aspects Med (2005) 1.27
Platelet-derived growth factor and reactive oxygen species (ROS) regulate Ras protein levels in primary human fibroblasts via ERK1/2. Amplification of ROS and Ras in systemic sclerosis fibroblasts. J Biol Chem (2005) 1.26
Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection. Cardiovasc Hematol Disord Drug Targets (2007) 1.25
Systemic sclerosis: current views of its pathogenesis. Autoimmun Rev (2003) 1.23
Role of repeated lung injury and genetic background in bleomycin-induced fibrosis. Am J Respir Cell Mol Biol (2003) 1.21
FAK is required for TGFbeta-induced JNK phosphorylation in fibroblasts: implications for acquisition of a matrix-remodeling phenotype. Mol Biol Cell (2007) 1.19
Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target. Biochem J (1997) 1.13
Gene transfection of H25A mutant heme oxygenase-1 protects cells against hydroperoxide-induced cytotoxicity. J Biol Chem (2002) 1.13
Serial circulating adhesion molecule levels reflect disease severity in systemic sclerosis. Br J Rheumatol (1995) 1.12
Antifibrotic role of inducible nitric oxide synthase. Nitric Oxide (2002) 1.11
Epigallocathechin-3 gallate inhibits cardiac hypertrophy through blocking reactive oxidative species-dependent and -independent signal pathways. Free Radic Biol Med (2006) 1.10
Clinical evidence of peroxynitrite formation in chronic renal failure patients with septic shock. Free Radic Biol Med (1997) 1.07
Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha. EMBO Rep (2002) 1.07
UV-induced immune suppression and photocarcinogenesis: chemoprevention by dietary botanical agents. Cancer Lett (2007) 1.05
Regulation of cardiac fibroblast extracellular matrix production by bradykinin and nitric oxide. J Mol Cell Cardiol (1999) 1.04
Vascular endothelial cell regulation of extracellular matrix collagen: role of nitric oxide. Arterioscler Thromb Vasc Biol (1998) 1.03
Serum levels of 8-isoprostane, a marker of oxidative stress, are elevated in patients with systemic sclerosis. Rheumatology (Oxford) (2006) 1.02
Nitric oxide inhibition of transforming growth factor-beta and collagen synthesis in mesangial cells. Diabetes (1997) 1.01
Evidence of free radical-mediated injury (isoprostane overproduction) in scleroderma. Arthritis Rheum (1996) 1.01
Nitric oxide stimulates the activity of a 72-kDa neutral matrix metalloproteinase in cultured rat mesangial cells. Biochem Biophys Res Commun (1996) 1.00
Scleroderma autoantigens are uniquely fragmented by metal-catalyzed oxidation reactions: implications for pathogenesis. J Exp Med (1997) 1.00
Effect of nitric oxide on the differentiation of fibroblasts into myofibroblasts in the Peyronie's fibrotic plaque and in its rat model. Nitric Oxide (2002) 0.99
Endothelial expression of nitric oxide synthases and nitrotyrosine in systemic sclerosis skin. J Pathol (1999) 0.99
Studies of the microvascular endothelium in uninvolved skin of patients with systemic sclerosis: direct evidence for a generalized microangiopathy. Br J Dermatol (1992) 0.99
Nitric oxide production and inducible nitric oxide synthase expression in systemic sclerosis. J Rheumatol (1998) 0.98
Correlation between increased nitric oxide production and markers of endothelial activation in systemic sclerosis: findings with the soluble adhesion molecules E-selectin, intercellular adhesion molecule 1, and vascular cell adhesion molecule 1. Arthritis Rheum (2000) 0.98
Beauty and the beast. The nitric oxide paradox in systemic sclerosis. Rheumatology (Oxford) (2002) 0.98
The antifibrogenic effect of (-)-epigallocatechin gallate results from the induction of de novo synthesis of glutathione in passaged rat hepatic stellate cells. Lab Invest (2006) 0.97
Green tea polyphenol epigallocatechin-3-gallate inhibits oxidative damage and preventive effects on carbon tetrachloride-induced hepatic fibrosis. J Nutr Biochem (2007) 0.96
Intracellular signaling network as a prime chemopreventive target of (-)-epigallocatechin gallate. Mol Nutr Food Res (2006) 0.96
The emerging problem of oxidative stress and the role of antioxidants in systemic sclerosis. Clin Exp Rheumatol (2001) 0.96
Green tea extract and (-)-epigallocatechin-3-gallate inhibit mast cell-stimulated type I collagen expression in keloid fibroblasts via blocking PI-3K/AkT signaling pathways. J Invest Dermatol (2006) 0.96
Induction of cell proliferation and collagen synthesis in human small intestinal lamina propria fibroblasts by lipopolysaccharide: possible involvement of nitric oxide. Biochem Biophys Res Commun (1997) 0.95
Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis. Toxicology (2000) 0.94
The antioxidant (-)-epigallocatechin-3-gallate inhibits activated hepatic stellate cell growth and suppresses acetaldehyde-induced gene expression. Biochem J (2002) 0.93
Nitric oxide modulates the synthesis of extracellular matrix proteins in cultured rat mesangial cells. Biochem Biophys Res Commun (1995) 0.93
Effect of nitric oxide and peroxynitrite on type I collagen synthesis in normal and scleroderma dermal fibroblasts. Free Radic Biol Med (2007) 0.91
Anti-endothelial cell antibodies in systemic sclerosis: significant association with vascular involvement and alveolo-capillary impairment. Clin Exp Rheumatol (1998) 0.91
Increased susceptibility to oxidation of low-density lipoproteins isolated from patients with systemic sclerosis. Arthritis Rheum (1995) 0.91
The aetiology of Raynaud's phenomenon. Cardiovasc Surg (1998) 0.91
Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenols. Biochem Biophys Res Commun (1997) 0.91
Monocytes of patients wiht systemic sclerosis (scleroderma spontaneously release in vitro increased amounts of superoxide anion. J Invest Dermatol (1999) 0.90
Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate. Rheumatology (Oxford) (2010) 0.90
Asymmetric dimethylarginine (ADMA): a key regulator of nitric oxide synthase. Atheroscler Suppl (2003) 0.90
(-)-Epigallocatechin gallate prevents carbon tetrachloride-induced rat hepatic fibrosis by inhibiting the expression of the PDGFRbeta and IGF-1R. Chem Biol Interact (2009) 0.90
Inhibition of NADPH oxidase subunits translocation by tea catechin EGCG in mast cell. Biochem Biophys Res Commun (2007) 0.90
Serum nitric oxide (NO) levels in systemic sclerosis patients: correlation between NO levels and clinical features. Clin Exp Immunol (2003) 0.89
Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90. J Hepatol (2004) 0.89
Antioxidants and CVD. Proc Nutr Soc (2008) 0.87
Intravenous N-acetylcysteine for treatment of Raynaud's phenomenon secondary to systemic sclerosis: a pilot study. J Rheumatol (2001) 0.86
Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine. Rheumatology (Oxford) (2006) 0.86
The role of protein nitration in the inhibition of platelet activation by peroxynitrite. FEBS Lett (2002) 0.84
Significant changes of peripheral perfusion and plasma adrenomedullin levels in N-acetylcysteine long term treatment of patients with sclerodermic Raynauds phenomenon. Int J Immunopathol Pharmacol (2006) 0.84
Impaired cholinergic dilator response of resistance arteries isolated from patients with Raynaud's disease. Br J Clin Pharmacol (1999) 0.84
Increased nitric oxide production in patients with systemic sclerosis. Nitric Oxide (2000) 0.83
Overexpression of nitric oxide synthase by the endothelium attenuates bleomycin-induced lung fibrosis and impairs MMP-9/TIMP-1 balance. Respirology (2006) 0.83
Antibodies against oxidized low-density lipoproteins in systemic sclerosis. Rheumatology (Oxford) (2001) 0.83
Nitric oxide modulates the c-Jun N-terminal kinase/stress-activated protein kinase activity through activating c-Jun N-terminal kinase kinase. Biochemistry (1997) 0.83
Nitric oxide and mechanisms of redox signalling: matrix and matrix-metabolizing enzymes as prime nitric oxide targets. Eur J Pharmacol (2001) 0.82
Increased urinary F2-isoprostanes in systemic sclerosis, but not in primary Raynaud's phenomenon: effect of cold exposure. Arthritis Rheum (2002) 0.82
Up-regulation by human recombinant transforming growth factor beta-1 of collagen production in cultured dermal fibroblasts is mediated by the inhibition of nitric oxide signaling. J Am Coll Surg (1999) 0.82
TGF-beta signaling and the fibrotic response. FASEB J (2004) 9.81
Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence? Lancet (2004) 6.37
All in the CCN family: essential matricellular signaling modulators emerge from the bunker. J Cell Sci (2006) 5.18
A polymorphism in the CTGF promoter region associated with systemic sclerosis. N Engl J Med (2007) 2.95
Identification of PLOD2 as telopeptide lysyl hydroxylase, an important enzyme in fibrosis. J Biol Chem (2003) 2.63
Connective tissue growth factor gene regulation. Requirements for its induction by transforming growth factor-beta 2 in fibroblasts. J Biol Chem (2003) 2.35
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts. Mol Biol Cell (2004) 2.29
Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis. Am J Clin Nutr (2006) 2.24
Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis. Thorax (2013) 2.17
Efficacy of the specific endothelin a receptor antagonist zibotentan (ZD4054) in colorectal cancer: a preclinical study. Mol Cancer Ther (2013) 2.05
CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. J Biol Chem (2006) 1.96
Inducible lineage-specific deletion of TbetaRII in fibroblasts defines a pivotal regulatory role during adult skin wound healing. J Invest Dermatol (2008) 1.92
Constitutive ALK5-independent c-Jun N-terminal kinase activation contributes to endothelin-1 overexpression in pulmonary fibrosis: evidence of an autocrine endothelin loop operating through the endothelin A and B receptors. Mol Cell Biol (2006) 1.87
CCN2 (connective tissue growth factor) promotes fibroblast adhesion to fibronectin. Mol Biol Cell (2004) 1.83
Shared expression of phenotypic markers in systemic sclerosis indicates a convergence of pericytes and fibroblasts to a myofibroblast lineage in fibrosis. Arthritis Res Ther (2005) 1.81
The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology. Biochem Cell Biol (2003) 1.80
CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC. Kidney Int (2002) 1.77
An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptor. Am J Respir Crit Care Med (2010) 1.76
Mechanisms and consequences of fibrosis in systemic sclerosis. Nat Clin Pract Rheumatol (2006) 1.73
Platelet-derived growth factor-beta receptor activation is essential for fibroblast and pericyte recruitment during cutaneous wound healing. Am J Pathol (2006) 1.70
Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen. Arthritis Rheum (2009) 1.65
Prostacyclin derivatives prevent the fibrotic response to TGF-beta by inhibiting the Ras/MEK/ERK pathway. FASEB J (2002) 1.64
Genetic variation at the SLC23A1 locus is associated with circulating concentrations of L-ascorbic acid (vitamin C): evidence from 5 independent studies with >15,000 participants. Am J Clin Nutr (2010) 1.61
CCN2 is necessary for the function of mouse embryonic fibroblasts. Exp Cell Res (2006) 1.57
Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts. Respir Res (2004) 1.55
Endothelin-1 induces expression of matrix-associated genes in lung fibroblasts through MEK/ERK. J Biol Chem (2004) 1.52
Insights into the molecular mechanism of chronic fibrosis: the role of connective tissue growth factor in scleroderma. J Invest Dermatol (2004) 1.52
The effect of dietary nitrate on salivary, plasma, and urinary nitrate metabolism in humans. Free Radic Biol Med (2003) 1.48
Retracted GSK-3beta in mouse fibroblasts controls wound healing and fibrosis through an endothelin-1-dependent mechanism. J Clin Invest (2008) 1.46
CCN2 is required for bleomycin-induced skin fibrosis in mice. Arthritis Rheum (2011) 1.46
Endogenous endothelin-1 signaling contributes to type I collagen and CCN2 overexpression in fibrotic fibroblasts. Matrix Biol (2007) 1.46
Endothelin is a downstream mediator of profibrotic responses to transforming growth factor beta in human lung fibroblasts. Arthritis Rheum (2007) 1.45
Regulation of collagen type I in vascular smooth muscle cells by competition between Nkx2.5 and deltaEF1/ZEB1. Mol Cell Biol (2004) 1.32
Connective tissue growth factor: a new and important player in the pathogenesis of fibrosis. Curr Rheumatol Rep (2002) 1.31
Contribution of activin receptor-like kinase 5 (transforming growth factor beta receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts. Arthritis Rheum (2006) 1.30
Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice. J Biol Chem (2003) 1.29
Loss of beta1 integrin in mouse fibroblasts results in resistance to skin scleroderma in a mouse model. Arthritis Rheum (2009) 1.25
Constitutive connective tissue growth factor expression in scleroderma fibroblasts is dependent on Sp1. J Biol Chem (2003) 1.24
Expression of integrin beta1 by fibroblasts is required for tissue repair in vivo. J Cell Sci (2010) 1.21
FAK is required for TGFbeta-induced JNK phosphorylation in fibroblasts: implications for acquisition of a matrix-remodeling phenotype. Mol Biol Cell (2007) 1.19
Loss of peroxisome proliferator-activated receptor gamma in mouse fibroblasts results in increased susceptibility to bleomycin-induced skin fibrosis. Arthritis Rheum (2009) 1.11
Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site. J Cell Biol (2002) 1.10
Monocyte chemoattractant protein 3 as a mediator of fibrosis: Overexpression in systemic sclerosis and the type 1 tight-skin mouse. Arthritis Rheum (2003) 1.07
Ghrelin can bind to a species of high density lipoprotein associated with paraoxonase. J Biol Chem (2003) 1.03
Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts. Arthritis Rheum (2008) 1.02
Loss of PTEN expression by dermal fibroblasts causes skin fibrosis. J Invest Dermatol (2011) 1.00
Requirement of transforming growth factor beta-activated kinase 1 for transforming growth factor beta-induced alpha-smooth muscle actin expression and extracellular matrix contraction in fibroblasts. Arthritis Rheum (2009) 0.99
Serum interleukin 6 is predictive of early functional decline and mortality in interstitial lung disease associated with systemic sclerosis. J Rheumatol (2013) 0.99
Angiogenic effects of stromal cell-derived factor-1 (SDF-1/CXCL12) variants in vitro and the in vivo expressions of CXCL12 variants and CXCR4 in human critical leg ischemia. J Vasc Surg (2010) 0.97
Rosiglitazone alleviates the persistent fibrotic phenotype of lesional skin scleroderma fibroblasts. Rheumatology (Oxford) (2009) 0.96
Endothelin-1 stimulates colon cancer adjacent fibroblasts. Int J Cancer (2011) 0.96
Epithelial cells promote fibroblast activation via IL-1alpha in systemic sclerosis. J Invest Dermatol (2010) 0.96
Rac inhibition reverses the phenotype of fibrotic fibroblasts. PLoS One (2009) 0.94
Fibroblast adhesion results in the induction of a matrix remodeling gene expression program. Matrix Biol (2008) 0.93
Oral L-arginine does not improve endothelial dysfunction in children with chronic renal failure. Kidney Int (2002) 0.93
Effect of vein graft harvesting on endothelial nitric oxide synthase and nitric oxide production. Ann Thorac Surg (2005) 0.93
Morphometric analysis of intralobular, interlobular and pleural lymphatics in normal human lung. J Anat (2012) 0.92
Anticoagulant and antiplatelet agents: their clinical and device application(s) together with usages to engineer surfaces. Biomacromolecules (2004) 0.92
Increased endogenous angiogenic response and hypoxia-inducible factor-1alpha in human critical limb ischemia. J Vasc Surg (2006) 0.92
Effect of nitric oxide and peroxynitrite on type I collagen synthesis in normal and scleroderma dermal fibroblasts. Free Radic Biol Med (2007) 0.91
Microarray profiling reveals suppressed interferon stimulated gene program in fibroblasts from scleroderma-associated interstitial lung disease. Respir Res (2013) 0.91
Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k). J Biol Chem (2005) 0.91
Cross-talk between MCP-3 and TGFbeta promotes fibroblast collagen biosynthesis. Exp Cell Res (2008) 0.91
Modulation of collagen type I, fibronectin and dermal fibroblast function and activity, in systemic sclerosis by the antioxidant epigallocatechin-3-gallate. Rheumatology (Oxford) (2010) 0.90
Role of Rac1 in a bleomycin-induced scleroderma model using fibroblast-specific Rac1-knockout mice. Arthritis Rheum (2008) 0.89
Transgenic analysis of scleroderma: understanding key pathogenic events in vivo. Autoimmun Rev (2004) 0.89
Pericytes display increased CCN2 expression upon culturing. J Cell Commun Signal (2009) 0.88
Does periadventitial fat-derived nitric oxide play a role in improved saphenous vein graft patency in patients undergoing coronary artery bypass surgery? J Vasc Res (2007) 0.87
Possible implication of the effector CD4+ T-cell subpopulation TH17 in the pathogenesis of systemic scleroderma. Nat Clin Pract Rheumatol (2007) 0.87
Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis. Blood (2002) 0.87
mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis. Arthritis Res Ther (2011) 0.87
Fibroblast-specific perturbation of transforming growth factor beta signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: exaggerated response to alveolar epithelial injury in a novel mouse model. Arthritis Rheum (2008) 0.87
Perivascular fat-derived leptin: a potential role in improved vein graft performance in coronary artery bypass surgery. Interact Cardiovasc Thorac Surg (2010) 0.86
Loss of protein kinase Cepsilon results in impaired cutaneous wound closure and myofibroblast function. J Cell Sci (2008) 0.86
Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts. Rheumatology (Oxford) (2012) 0.85
Failed degradation of JunB contributes to overproduction of type I collagen and development of dermal fibrosis in patients with systemic sclerosis. Arthritis Rheumatol (2015) 0.84
The role of protein nitration in the inhibition of platelet activation by peroxynitrite. FEBS Lett (2002) 0.84
Lymphatic and blood vessels in scleroderma skin, a morphometric analysis. Hum Pathol (2009) 0.82
Observational versus randomised trial evidence. Lancet (2004) 0.82
Hammerhead ribozyme-mediated silencing of the mutant fibrillin-1 of tight skin mouse: insight into the functional role of mutant fibrillin-1. Exp Cell Res (2006) 0.82
Signaling pathways regulating intercellular adhesion molecule 1 expression by endothelin 1: comparison with interleukin-1beta in normal and scleroderma dermal fibroblasts. Arthritis Rheum (2006) 0.82
Hypoxia-inducible factor 1 in lower limb ischemia. Vascular (2006) 0.82
Stem cells of the lower limb: their role and potential in management of critical limb ischemia. Exp Biol Med (Maywood) (2013) 0.81
Potential of Novel EPO Derivatives in Limb Ischemia. Cardiol Res Pract (2012) 0.81
Elevated CCN2 expression in scleroderma: a putative role for the TGFβ accessory receptors TGFβRIII and endoglin. J Cell Commun Signal (2011) 0.81
The nitration of proteins in platelets: significance in platelet function. Free Radic Biol Med (2002) 0.80
Temporal relationships between circulating levels of CC and CXC chemokines and developing atherosclerosis in apolipoprotein E*3 Leiden mice. Arterioscler Thromb Vasc Biol (2003) 0.80
Differential functions of tissue factor in the trans-activation of cellular signalling pathways. Atherosclerosis (2006) 0.79
Cyclic mechanical stress downregulates endothelin-1 and its responsive genes independently of TGFβ1 in dermal fibroblasts. Exp Dermatol (2012) 0.78
Development of an in vitro model of myotube ischemia. Lab Invest (2011) 0.76
Review of the role of erythropoietin in critical leg ischemia. Angiology (2010) 0.76
The state of macrophage differentiation determines the TNF alpha response to nitrated lipoprotein uptake. Atherosclerosis (2003) 0.76
Cell signalling pathways leading to novel therapeutic strategies in cardiovascular disease. Cardiol Res Pract (2012) 0.75
Agonistic anti-ICAM-1 antibodies in scleroderma: activation of endothelial pro-inflammatory cascades. Vascul Pharmacol (2013) 0.75
Roles for prostaglandins in the steroidogenic response of human granulosa cells to high-density lipoproteins. Mol Cell Endocrinol (2004) 0.75
Nitric oxide signaling in platelets. Methods Mol Biol (2004) 0.75
Smoking has no effect on the amino acid composition of apolipoprotein B100 of LDL while directly influencing the antioxidant status. Biochem Biophys Res Commun (2002) 0.75