Published in Mol Nutr Food Res on December 01, 2011
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Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. Nat Med (2010) 2.76
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
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Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis. J Clin Invest (2007) 2.03
Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis. BMC Syst Biol (2007) 2.01
Differential lipid partitioning between adipocytes and tissue macrophages modulates macrophage lipotoxicity and M2/M1 polarization in obese mice. Diabetes (2011) 1.91
Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans. PLoS Biol (2011) 1.89
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The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform. Diabetes (2005) 1.76
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CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance. Cell Metab (2009) 1.68
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Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway. J Biol Chem (2009) 1.60
Serum vitamin D concentration does not predict insulin action or secretion in European subjects with the metabolic syndrome. Diabetes Care (2010) 1.59
IGF-binding protein-2 protects against the development of obesity and insulin resistance. Diabetes (2007) 1.56
Effect of acute dietary standardization on the urinary, plasma, and salivary metabolomic profiles of healthy humans. Am J Clin Nutr (2006) 1.53
Response to a urate-lowering diet according to polymorphisms in the apolipoprotein AI-CIII-AIV cluster. J Rheumatol (2005) 1.53
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ETO/MTG8 is an inhibitor of C/EBPbeta activity and a regulator of early adipogenesis. Mol Cell Biol (2004) 1.52
Using brown adipose tissue to treat obesity - the central issue. Trends Mol Med (2011) 1.51
Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta. PLoS One (2008) 1.50
Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers. Am J Clin Nutr (2012) 1.49
Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies. Front Endocrinol (Lausanne) (2013) 1.47
Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia. Cardiovasc Res (2011) 1.46
The nodule inception-like protein 7 modulates nitrate sensing and metabolism in Arabidopsis. Plant J (2008) 1.46
Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese. Biochem Soc Trans (2008) 1.45
Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am J Clin Nutr (2004) 1.44
Fats, inflammation and insulin resistance: insights to the role of macrophage and T-cell accumulation in adipose tissue. Proc Nutr Soc (2011) 1.43
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Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice. Diabetes (2006) 1.39
Docosahexaenoic acid induces an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophages more effectively than eicosapentaenoic acid. J Nutr Biochem (2006) 1.38
Visfatin: the missing link between intra-abdominal obesity and diabetes? Trends Mol Med (2005) 1.37
Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages. J Nutr Biochem (2009) 1.37
Informatics and computational strategies for the study of lipids. Mol Biosyst (2007) 1.37
DNA damage links mitochondrial dysfunction to atherosclerosis and the metabolic syndrome. Circ Res (2010) 1.36
Digenic inheritance of severe insulin resistance in a human pedigree. Nat Genet (2002) 1.36
Beyond the sympathetic tone: the new brown fat activators. Cell Metab (2013) 1.32
Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue. Diabetes (2007) 1.31
PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy. Circ Res (2011) 1.31
Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis. Diabetes (2011) 1.30
Decreased brown adipocyte recruitment and thermogenic capacity in mice with impaired peroxisome proliferator-activated receptor (P465L PPARgamma) function. Endocrinology (2006) 1.29
Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. Diabetes (2012) 1.28
Assessment and clinical relevance of non-fasting and postprandial triglycerides: an expert panel statement. Curr Vasc Pharmacol (2011) 1.27
Regional differences in the response of human pre-adipocytes to PPARgamma and RXRalpha agonists. Diabetes (2002) 1.27
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice. Free Radic Biol Med (2009) 1.26
Characterisation of the phosphorylation of beta-catenin at the GSK-3 priming site Ser45. Biochem Biophys Res Commun (2002) 1.26
A MUFA-rich diet improves posprandial glucose, lipid and GLP-1 responses in insulin-resistant subjects. J Am Coll Nutr (2007) 1.26
Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis. J Biol Chem (2003) 1.25
The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr (2005) 1.24
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Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender. FASEB J (2010) 1.16
Hemoglobin A1c versus oral glucose tolerance test in postpartum diabetes screening. Diabetes Care (2012) 1.15
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The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects. Br J Nutr (2002) 1.14
Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet. Cell Metab (2013) 1.14
Benefits of polyphenols on gut microbiota and implications in human health. J Nutr Biochem (2013) 1.13
The gene expression of the main lipogenic enzymes is downregulated in visceral adipose tissue of obese subjects. Obesity (Silver Spring) (2009) 1.12
Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels. PLoS One (2013) 1.12
Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver. Physiol Genomics (2009) 1.11
Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men. Atherosclerosis (2008) 1.11
Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction. J Immunol (2005) 1.11
Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA. J Nutr Biochem (2011) 1.11
The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ApoE-/- mice. Free Radic Biol Med (2011) 1.10
Metabolic phenotyping of a model of adipocyte differentiation. Physiol Genomics (2009) 1.10
Below thermoneutrality, changes in activity do not drive changes in total daily energy expenditure between groups of mice. Cell Metab (2012) 1.10
Adipose tissue gene expression of factors related to lipid processing in obesity. PLoS One (2011) 1.10
Adipogenesis and lipotoxicity: role of peroxisome proliferator-activated receptor gamma (PPARgamma) and PPARgammacoactivator-1 (PGC1). Public Health Nutr (2007) 1.09
Stimulation of mitochondrial proton conductance by hydroxynonenal requires a high membrane potential. Biosci Rep (2008) 1.09
Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability. Endocrinology (2008) 1.08
Regulation of adiponectin expression in human adipocytes: effects of adiposity, glucocorticoids, and tumor necrosis factor alpha. Obes Res (2005) 1.08
The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA. Proc Nutr Soc (2010) 1.06
Mediterranean diet reduces endothelial damage and improves the regenerative capacity of endothelium. Am J Clin Nutr (2010) 1.06
Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis. FASEB J (2005) 1.06