Published in Biosens Bioelectron on November 10, 2011
Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Res (2014) 0.78
Real-time surface plasmon resonance study of biomolecular interactions between polymerase and bulky mutagenic DNA lesions. Chem Res Toxicol (2014) 0.76
A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. Science (2008) 29.99
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
International network of cancer genome projects. Nature (2010) 20.35
A human protein-protein interaction network: a resource for annotating the proteome. Cell (2005) 18.97
Transcriptome analysis by strand-specific sequencing of complementary DNA. Nucleic Acids Res (2009) 9.40
Transcriptome and genome sequencing uncovers functional variation in humans. Nature (2013) 8.89
The DNA sequence of the human X chromosome. Nature (2005) 6.97
5S Ribosomal RNA Database. Nucleic Acids Res (2002) 5.95
The genome of a songbird. Nature (2010) 5.90
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol (2011) 4.84
Dissecting the genomic complexity underlying medulloblastoma. Nature (2012) 4.77
Mutations in DNAH5 cause primary ciliary dyskinesia and randomization of left-right asymmetry. Nat Genet (2002) 4.64
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet (2012) 4.27
Prediction of alternative isoforms from exon expression levels in RNA-Seq experiments. Nucleic Acids Res (2010) 3.36
A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. Mol Cell (2004) 3.26
BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells (2010) 3.17
Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell (2013) 3.08
Automated Gene Ontology annotation for anonymous sequence data. Nucleic Acids Res (2003) 3.02
Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications. Genome Res (2004) 3.02
GOblet: a platform for Gene Ontology annotation of anonymous sequence data. Nucleic Acids Res (2004) 2.99
The ConsensusPathDB interaction database: 2013 update. Nucleic Acids Res (2012) 2.94
Construction and analysis of a human-chimpanzee comparative clone map. Science (2002) 2.83
ConsensusPathDB: toward a more complete picture of cell biology. Nucleic Acids Res (2010) 2.79
ConsensusPathDB--a database for integrating human functional interaction networks. Nucleic Acids Res (2008) 2.77
A gene expression map of human chromosome 21 orthologues in the mouse. Nature (2002) 2.76
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress. J Biol (2007) 2.70
Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage. Genome Res (2010) 2.61
Design of antisense oligonucleotides stabilized by locked nucleic acids. Nucleic Acids Res (2002) 2.58
Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica. Nature (2004) 2.54
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proc Natl Acad Sci U S A (2007) 2.50
T cells become licensed in the lung to enter the central nervous system. Nature (2012) 2.45
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma. Nat Genet (2013) 2.42
Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules. Mol Biol Cell (2007) 2.30
Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome. Genome Res (2004) 2.29
Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics (2011) 2.24
A comparison of oligonucleotide and cDNA-based microarray systems. Physiol Genomics (2004) 2.21
On the origin of the chordate central nervous system: expression of onecut in the sea urchin embryo. Evol Dev (2004) 2.19
Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells. Stem Cells (2006) 2.18
MicroRNA profiling of clear cell renal cell cancer identifies a robust signature to define renal malignancy. J Cell Mol Med (2009) 2.12
Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis. PLoS One (2010) 2.10
Characterizing the mouse ES cell transcriptome with Illumina sequencing. Genomics (2008) 2.09
Genome-wide massively parallel sequencing of formaldehyde fixed-paraffin embedded (FFPE) tumor tissues for copy-number- and mutation-analysis. PLoS One (2009) 2.04
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
Mechanistic insights into the superoxide-cytochrome c reaction by lysine surface scanning. J Biol Inorg Chem (2013) 1.97
Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes Dev (2008) 1.96
Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal. Stem Cells (2006) 1.88
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays. PLoS Med (2005) 1.88
Plasticity of animal genome architecture unmasked by rapid evolution of a pelagic tunicate. Science (2010) 1.86
Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions. J Mol Biol (2005) 1.86
TLR2 has a detrimental role in mouse transient focal cerebral ischemia. Biochem Biophys Res Commun (2007) 1.84
An efficient and economic enhancer mix for PCR. Biochem Biophys Res Commun (2006) 1.82
A centrosome-independent role for gamma-TuRC proteins in the spindle assembly checkpoint. Science (2006) 1.76
High throughput identification of potential Arabidopsis mitogen-activated protein kinases substrates. Mol Cell Proteomics (2005) 1.75
Genetic analysis of the mouse brain proteome. Nat Genet (2002) 1.73
Alternative pathways as mechanism for the negative effects associated with overexpression of superoxide dismutase. J Theor Biol (2005) 1.71
Primary differentiation in the human blastocyst: comparative molecular portraits of inner cell mass and trophectoderm cells. Stem Cells (2005) 1.68
No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis. Oncotarget (2011) 1.68
New evidence for genome-wide duplications at the origin of vertebrates using an amphioxus gene set and completed animal genomes. Genome Res (2003) 1.65
Targeted enrichment of genomic DNA regions for next-generation sequencing. Brief Funct Genomics (2011) 1.63
Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity. J Exp Med (2012) 1.57
Application of locked nucleic acids to improve aptamer in vivo stability and targeting function. Nucleic Acids Res (2004) 1.54
A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth. Proc Natl Acad Sci U S A (2008) 1.54
Detection of angiotensin II in supernatants of stimulated mononuclear leukocytes by matrix-assisted laser desorption ionization time-of-flight/time-of-flight mass analysis. Hypertension (2005) 1.52
Clone-based systematic haplotyping (CSH): a procedure for physical haplotyping of whole genomes. Genome Res (2003) 1.45
Miniaturization in functional genomics and proteomics. Nat Rev Genet (2005) 1.44
Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA. Nucleic Acids Res (2003) 1.42
Human induced pluripotent stem cells harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining human embryonic stem cell-like metabolic reprogramming. Stem Cells (2011) 1.42
Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells. Cell Metab (2011) 1.40
The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. J Biol Chem (2011) 1.36
Probing the SELEX process with next-generation sequencing. PLoS One (2011) 1.34
A new frontier for molecular medicine: noncoding RNAs. Biochim Biophys Acta (2005) 1.31
A nonredundant human protein chip for antibody screening and serum profiling. Mol Cell Proteomics (2003) 1.31
The pentose phosphate pathway is a metabolic redox sensor and regulates transcription during the antioxidant response. Antioxid Redox Signal (2011) 1.31
A data integration approach to mapping OCT4 gene regulatory networks operative in embryonic stem cells and embryonal carcinoma cells. PLoS One (2010) 1.31
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay. Proc Natl Acad Sci U S A (2002) 1.30
High heterogeneity within the ribosomal proteins of the Arabidopsis thaliana 80S ribosome. Plant Mol Biol (2005) 1.30
Toward optimized antibody microarrays: a comparison of current microarray support materials. Anal Biochem (2002) 1.29
Noncoding regulatory RNAs database. Nucleic Acids Res (2003) 1.29
Genome-wide array analysis of normal and malformed human hearts. Circulation (2003) 1.28
Generation of high density protein microarrays by cell-free in situ expression of unpurified PCR products. Mol Cell Proteomics (2006) 1.28
Proteomic and functional analysis of the mitotic Drosophila centrosome. EMBO J (2010) 1.27
Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells. EMBO Mol Med (2012) 1.27
An integrative approach to gain insights into the cellular function of human ataxin-2. J Mol Biol (2004) 1.26
Reverse engineering of gene regulatory networks: a comparative study. EURASIP J Bioinform Syst Biol (2009) 1.22
Silencing of core transcription factors in human EC cells highlights the importance of autocrine FGF signaling for self-renewal. BMC Dev Biol (2007) 1.21
Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways. Hum Mol Genet (2005) 1.21
Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discov (2012) 1.21
5 S rRNA: structure and interactions. Biochem J (2003) 1.20
Next generation of protein microarray support materials: evaluation for protein and antibody microarray applications. J Chromatogr A (2003) 1.20
Engineered superoxide dismutase monomers for superoxide biosensor applications. Anal Chem (2006) 1.20
Regulatory crosstalk of the metabolic network. Trends Biochem Sci (2010) 1.20
A global view of gene expression in lithium and zinc treated sea urchin embryos: new components of gene regulatory networks. Genome Biol (2007) 1.19
Control of early fate decisions in human ES cells by distinct states of TGFbeta pathway activity. Stem Cells Dev (2008) 1.19
Application of housekeeping npcRNAs for quantitative expression analysis of human transcriptome by real-time PCR. RNA (2009) 1.17