PubRank

Brendan W Wren

Author PubWeight™ 156.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet 2006 8.02
2 The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat Genet 2005 6.22
3 Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nat Genet 2012 4.10
4 N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science 2002 4.04
5 Protein glycosylation in bacterial mucosal pathogens. Nat Rev Microbiol 2005 3.75
6 Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol 2009 3.66
7 Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. Infect Immun 2009 3.36
8 The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081. PLoS Genet 2006 3.33
9 Evolutionary dynamics of Clostridium difficile over short and long time scales. Proc Natl Acad Sci U S A 2010 3.18
10 Bacterial pathogenomics. Nature 2007 3.16
11 Application of DNA microarrays to study the evolutionary genomics of Yersinia pestis and Yersinia pseudotuberculosis. Genome Res 2003 2.51
12 Re-annotation and re-analysis of the Campylobacter jejuni NCTC11168 genome sequence. BMC Genomics 2007 2.31
13 Bacterial epidemiology and biology--lessons from genome sequencing. Genome Biol 2011 2.18
14 Functional analysis of the Campylobacter jejuni N-linked protein glycosylation pathway. Mol Microbiol 2005 2.16
15 Campylobacter--a tale of two protein glycosylation systems. Trends Microbiol 2003 2.10
16 Comparative phylogenomics of the food-borne pathogen Campylobacter jejuni reveals genetic markers predictive of infection source. Proc Natl Acad Sci U S A 2005 2.04
17 The Clostridium difficile spo0A gene is a persistence and transmission factor. Infect Immun 2012 2.02
18 A novel paralogous gene family involved in phase-variable flagella-mediated motility in Campylobacter jejuni. Microbiology 2002 1.84
19 Parallel independent evolution of pathogenicity within the genus Yersinia. Proc Natl Acad Sci U S A 2014 1.83
20 Analysis of Campylobacter jejuni capsular loci reveals multiple mechanisms for the generation of structural diversity and the ability to form complex heptoses. Mol Microbiol 2005 1.79
21 Adaptation of Campylobacter jejuni NCTC11168 to high-level colonization of the avian gastrointestinal tract. Infect Immun 2004 1.77
22 Identification of N-acetylgalactosamine-containing glycoproteins PEB3 and CgpA in Campylobacter jejuni. Mol Microbiol 2002 1.62
23 Comparative analysis of BI/NAP1/027 hypervirulent strains reveals novel toxin B-encoding gene (tcdB) sequences. J Med Microbiol 2008 1.54
24 Effect of chicken meat environment on gene expression of Campylobacter jejuni and its relevance to survival in food. Int J Food Microbiol 2010 1.49
25 Invertebrates as a source of emerging human pathogens. Nat Rev Microbiol 2004 1.45
26 Macro and micro diversity of Clostridium difficile isolates from diverse sources and geographical locations. PLoS One 2012 1.40
27 Campylobacter jejuni glycosylation island important in cell charge, legionaminic acid biosynthesis, and colonization of chickens. Infect Immun 2009 1.35
28 Application of comparative phylogenomics to study the evolution of Yersinia enterocolitica and to identify genetic differences relating to pathogenicity. J Bacteriol 2006 1.29
29 Revised nomenclature of Clostridium difficile toxins and associated genes. J Med Microbiol 2005 1.28
30 Galleria mellonella as an alternative infection model for Yersinia pseudotuberculosis. Microbiology 2009 1.23
31 Characterisation of Clostridium difficile biofilm formation, a role for Spo0A. PLoS One 2012 1.21
32 Explorative multifactor approach for investigating global survival mechanisms of Campylobacter jejuni under environmental conditions. Appl Environ Microbiol 2005 1.20
33 Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress. J Med Microbiol 2008 1.20
34 Comparative phylogenomics of pathogenic bacteria by microarray analysis. Curr Opin Microbiol 2005 1.20
35 The RovA regulons of Yersinia enterocolitica and Yersinia pestis are distinct: evidence that many RovA-regulated genes were acquired more recently than the core genome. Mol Microbiol 2007 1.18
36 Mucosal immunization with a urease B DNA vaccine induces innate and cellular immune responses against Helicobacter pylori. Helicobacter 2006 1.18
37 The second century of Campylobacter research: recent advances, new opportunities and old problems. Curr Opin Infect Dis 2007 1.17
38 Commonality and biosynthesis of the O-methyl phosphoramidate capsule modification in Campylobacter jejuni. J Biol Chem 2007 1.16
39 Serotype differences and lack of biofilm formation characterize Yersinia pseudotuberculosis infection of the Xenopsylla cheopis flea vector of Yersinia pestis. J Bacteriol 2006 1.16
40 Intestinal innate immunity to Campylobacter jejuni results in induction of bactericidal human beta-defensins 2 and 3. Infect Immun 2005 1.16
41 Emergence of new PCR ribotypes from the hypervirulent Clostridium difficile 027 lineage. J Med Microbiol 2011 1.16
42 Structural characterization of lipo-oligosaccharide (LOS) from Yersinia pestis: regulation of LOS structure by the PhoPQ system. Mol Microbiol 2002 1.15
43 Gene content and diversity of the loci encoding biosynthesis of capsular polysaccharides of the 15 serovar reference strains of Haemophilus parasuis. J Bacteriol 2013 1.13
44 Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection. PLoS One 2010 1.13
45 Insect infection model for Campylobacter jejuni reveals that O-methyl phosphoramidate has insecticidal activity. J Infect Dis 2010 1.13
46 Campylobacter jejuni-mediated disease pathogenesis: an update. Trans R Soc Trop Med Hyg 2007 1.13
47 A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni. Cell Microbiol 2007 1.11
48 The Campylobacter jejuni glycome. FEMS Microbiol Rev 2005 1.11
49 Characterization of the Burkholderia pseudomallei K96243 capsular polysaccharide I coding region. Infect Immun 2012 1.07
50 Clostridium difficile--a continually evolving and problematic pathogen. Infect Genet Evol 2009 1.06
51 The Campylobacter jejuni transcriptional regulator Cj1556 plays a role in the oxidative and aerobic stress response and is important for bacterial survival in vivo. J Bacteriol 2011 1.05
52 Neutrophil extracellular traps exhibit antibacterial activity against burkholderia pseudomallei and are influenced by bacterial and host factors. Infect Immun 2012 1.04
53 Genomic variations define divergence of water/wildlife-associated Campylobacter jejuni niche specialists from common clonal complexes. Environ Microbiol 2011 1.04
54 Hypervirulent Clostridium difficile PCR-ribotypes exhibit resistance to widely used disinfectants. PLoS One 2011 0.99
55 Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells. Infect Immun 2012 0.98
56 Characterization of the structurally diverse N-linked glycans of Campylobacter species. J Bacteriol 2012 0.97
57 Deletion of a previously uncharacterized flagellar-hook-length control gene fliK modulates the sigma54-dependent regulon in Campylobacter jejuni. Microbiology 2007 0.96
58 Numerical analysis of DNA microarray data of Campylobacter jejuni strains correlated with survival, cytolethal distending toxin and haemolysin analyses. Int J Med Microbiol 2006 0.95
59 The agr locus regulates virulence and colonization genes in Clostridium difficile 027. J Bacteriol 2013 0.95
60 Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system. BMC Microbiol 2010 0.94
61 Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. MBio 2014 0.94
62 Development of a self-replicating plasmid system for Mycoplasma hyopneumoniae. Vet Res 2013 0.93
63 The identification of two protective DNA vaccines from a panel of five plasmid constructs encoding Brucella melitensis 16M genes. Vaccine 2006 0.92
64 In-depth genetic analysis of Clostridium difficile PCR-ribotype 027 strains reveals high genome fluidity including point mutations and inversions. Gut Microbes 2010 0.92
65 Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores. PLoS One 2013 0.92
66 Genomic epidemiology of Vibrio cholerae O1 associated with floods, Pakistan, 2010. Emerg Infect Dis 2014 0.92
67 The analysis of para-cresol production and tolerance in Clostridium difficile 027 and 012 strains. BMC Microbiol 2011 0.92
68 Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli. Infect Immun 2013 0.92
69 Yersinia pseudotuberculosis mntH functions in intracellular manganese accumulation, which is essential for virulence and survival in cells expressing functional Nramp1. Microbiology 2010 0.91
70 Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis. Open Biol 2013 0.90
71 Transposon mutagenesis in Mycoplasma hyopneumoniae using a novel mariner-based system for generating random mutations. Vet Res 2013 0.89
72 The continually evolving Clostridium difficile species. Future Microbiol 2012 0.89
73 Helicobacter pylori adherence to gastric epithelial cells: a role for non-adhesin virulence genes. J Med Microbiol 2002 0.89
74 Clostridium difficile modulates host innate immunity via toxin-independent and dependent mechanism(s). PLoS One 2013 0.88
75 Genes to genetic immunization: identification of bacterial vaccine candidates. Methods 2003 0.88
76 Administration of capsule-selective endosialidase E minimizes upregulation of organ gene expression induced by experimental systemic infection with Escherichia coli K1. Microbiology 2010 0.87
77 Steps toward broad-spectrum therapeutics: discovering virulence-associated genes present in diverse human pathogens. BMC Genomics 2009 0.87
78 Increase in Campylobacter jejuni invasion of intestinal epithelial cells under low-oxygen coculture conditions that reflect the in vivo environment. Infect Immun 2012 0.87
79 The Campylobacter jejuni NCTC11168 capsule prevents excessive cytokine production by dendritic cells. Med Microbiol Immunol 2011 0.86
80 N-linked glycosylation in bacteria: an unexpected application. Future Microbiol 2009 0.86
81 Recent developments in bacterial protein glycan coupling technology and glycoconjugate vaccine design. J Med Microbiol 2012 0.86
82 Assessing the role of p-cresol tolerance in Clostridium difficile. J Med Microbiol 2008 0.85
83 Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching. BMC Genomics 2010 0.85
84 Biofilm development on Caenorhabditis elegans by Yersinia is facilitated by quorum sensing-dependent repression of type III secretion. PLoS Pathog 2011 0.85
85 Comparative genome analyses of the pathogenic Yersiniae based on the genome sequence of Yersinia enterocolitica strain 8081. Adv Exp Med Biol 2007 0.85
86 Development and application of the active surveillance of pathogens microarray to monitor bacterial gene flux. BMC Microbiol 2008 0.85
87 Glycoproteomics: a powerful tool for characterizing the diverse glycoforms of bacterial pilins and flagellins. Biochem Soc Trans 2010 0.84
88 The importance of the Rcs phosphorelay in the survival and pathogenesis of the enteropathogenic yersiniae. Microbiology 2008 0.83
89 Campylobacter jejuni lipooligosaccharide sialylation, phosphorylation, and amide/ester linkage modifications fine-tune human Toll-like receptor 4 activation. J Biol Chem 2013 0.82
90 Population biology of Streptococcus pneumoniae in West Africa: multilocus sequence typing of serotypes that exhibit different predisposition to invasive disease and carriage. PLoS One 2013 0.82
91 The post-translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence. Mol Microbiol 2014 0.82
92 Improved bacterial mutagenesis by high-frequency allele exchange, demonstrated in Clostridium difficile and Streptococcus suis. Appl Environ Microbiol 2013 0.82
93 Generation of a Tn5 transposon library in Haemophilus parasuis and analysis by transposon-directed insertion-site sequencing (TraDIS). Vet Microbiol 2013 0.81
94 Yersinia enterocolitica provides the link between thyroid-stimulating antibodies and their germline counterparts in Graves' disease. J Immunol 2013 0.81
95 Gene function hypotheses for the Campylobacter jejuni glycome generated by a logic-based approach. J Mol Biol 2012 0.80
96 Identification of possible virulence marker from Campylobacter jejuni isolates. Emerg Infect Dis 2014 0.80
97 Growth inhibition of pathogenic bacteria by sulfonylurea herbicides. Antimicrob Agents Chemother 2012 0.80
98 YtxR acts as an overriding transcriptional off switch for the Yersinia enterocolitica Ysc-Yop type 3 secretion system. J Bacteriol 2008 0.80
99 Comparative phylogenomics of Streptococcus pneumoniae isolated from invasive disease and nasopharyngeal carriage from West Africans. BMC Genomics 2012 0.80
100 Identification of immunogenic and virulence-associated Campylobacter jejuni proteins. Clin Vaccine Immunol 2011 0.80
101 Phenotypic and genotypic characterizations of Campylobacter jejuni isolated from the broiler meat production process. Curr Microbiol 2012 0.79
102 Signature-tagged mutagenesis of Yersinia pestis. Adv Exp Med Biol 2003 0.79
103 Identification and characterisation of a novel adhesin Ifp in Yersinia pseudotuberculosis. BMC Microbiol 2011 0.79
104 Liposomal delivery of p-ialB and p-omp25 DNA vaccines improves immunogenicity but fails to provide full protection against B. melitensis challenge. Genet Vaccines Ther 2010 0.78
105 New levels of sophistication in the transcriptional landscape of bacteria. Genome Biol 2009 0.78
106 Recent advances in systems microbiology. Curr Opin Microbiol 2009 0.78
107 The twin arginine translocation system is essential for aerobic growth and full virulence of Burkholderia thailandensis. J Bacteriol 2013 0.78
108 Evidence of Yersinia pestis DNA from fleas in an endemic plague area of Zambia. BMC Res Notes 2012 0.78
109 Bacteria like sharing their sweets. Mol Microbiol 2013 0.77
110 BμG@Sbase--a microbial gene expression and comparative genomic database. Nucleic Acids Res 2011 0.77
111 Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays. Environ Microbiol 2013 0.77
112 Clostridium difficile comes of age. Future Microbiol 2006 0.77
113 Escherichia coli pathotypes in Pakistan from consecutive floods in 2010 and 2011. Am J Trop Med Hyg 2013 0.76
114 Systems analysis of bacterial glycomes. Biochem Soc Trans 2010 0.76
115 Deciphering tsetse's secret partner. Nat Genet 2002 0.76
116 Erratum: Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. Nat Commun 2015 0.76
117 Enteric bacterial invasion of intestinal epithelial cells in vitro is dramatically enhanced using a vertical diffusion chamber model. J Vis Exp 2013 0.75
118 Microarray analysis of campylobacter jejuni: to the guts of the problem! Comp Funct Genomics 2002 0.75
119 Shared characteristics between Mycobacterium tuberculosis and fungi contribute to virulence. Future Microbiol 2014 0.75