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1
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Mechanisms of leptin action and leptin resistance.
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Annu Rev Physiol
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2008
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4.72
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2
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A guide to analysis of mouse energy metabolism.
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Nat Methods
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2011
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3.82
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3
|
Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding.
|
Cell Metab
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2009
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3.07
|
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4
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The geometry of leptin action in the brain: more complicated than a simple ARC.
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Cell Metab
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2009
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2.69
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5
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Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.
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J Clin Invest
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2006
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2.38
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6
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Leptin receptor signaling and action in the central nervous system.
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Obesity (Silver Spring)
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2006
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1.92
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7
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Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function.
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J Clin Invest
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2007
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1.91
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8
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Critical role for hypothalamic mTOR activity in energy balance.
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Cell Metab
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2009
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1.90
|
|
9
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Direct innervation of GnRH neurons by metabolic- and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus.
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J Neurosci
|
2009
|
1.85
|
|
10
|
Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits.
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J Neurosci
|
2011
|
1.82
|
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11
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FGF21 is an endocrine signal of protein restriction.
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J Clin Invest
|
2014
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1.76
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12
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The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms.
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J Biol Chem
|
2007
|
1.53
|
|
13
|
Differential accessibility of circulating leptin to individual hypothalamic sites.
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Endocrinology
|
2007
|
1.48
|
|
14
|
The lateral hypothalamus as integrator of metabolic and environmental needs: from electrical self-stimulation to opto-genetics.
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Physiol Behav
|
2011
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1.47
|
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15
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Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging.
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Cell Metab
|
2013
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1.45
|
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16
|
Ventral tegmental area leptin receptor neurons specifically project to and regulate cocaine- and amphetamine-regulated transcript neurons of the extended central amygdala.
|
J Neurosci
|
2010
|
1.43
|
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17
|
Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation.
|
Cell Metab
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2007
|
1.39
|
|
18
|
Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.
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J Neurosci
|
2009
|
1.32
|
|
19
|
Critical roles for the TSC-mTOR pathway in β-cell function.
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Am J Physiol Endocrinol Metab
|
2009
|
1.20
|
|
20
|
Complex regulation of mammalian target of rapamycin complex 1 in the basomedial hypothalamus by leptin and nutritional status.
|
Endocrinology
|
2009
|
1.19
|
|
21
|
GLP-1 receptor signaling is not required for reduced body weight after RYGB in rodents.
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Am J Physiol Regul Integr Comp Physiol
|
2014
|
1.16
|
|
22
|
Neural and metabolic regulation of macronutrient intake and selection.
|
Proc Nutr Soc
|
2012
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1.04
|
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23
|
Early-life exposure to testosterone programs the hypothalamic melanocortin system.
|
Endocrinology
|
2011
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1.01
|
|
24
|
N-acetylation of hypothalamic alpha-melanocyte-stimulating hormone and regulation by leptin.
|
Proc Natl Acad Sci U S A
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2004
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1.00
|
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25
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Leptin receptor neurons in the mouse hypothalamus are colocalized with the neuropeptide galanin and mediate anorexigenic leptin action.
|
Am J Physiol Endocrinol Metab
|
2013
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1.00
|
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26
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gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor.
|
Proc Natl Acad Sci U S A
|
2006
|
0.99
|
|
27
|
Role of signal transducer and activator of transcription 3 in regulation of hypothalamic trh gene expression by leptin.
|
Endocrinology
|
2004
|
0.98
|
|
28
|
Impaired branched chain amino acid metabolism alters feeding behavior and increases orexigenic neuropeptide expression in the hypothalamus.
|
J Endocrinol
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2011
|
0.86
|
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29
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Integration of sensory information via central thermoregulatory leptin targets.
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Physiol Behav
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2013
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0.84
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|
30
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Reversible hyperphagia and obesity in rats with gastric bypass by central MC3/4R blockade.
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Obesity (Silver Spring)
|
2014
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0.83
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31
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Capricious Cre: the devil is in the details.
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Endocrinology
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2012
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0.82
|
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32
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Central mechanisms of adiposity in adult female mice with androgen excess.
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Obesity (Silver Spring)
|
2014
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0.82
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33
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Novel aspects of brown adipose tissue biology.
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Endocrinol Metab Clin North Am
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2012
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0.78
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34
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The Hypothalamic Preoptic Area and Body Weight Control.
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Neuroendocrinology
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2017
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0.75
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