Published in Sci Signal on January 03, 2012
Occult HBV infection. Semin Immunopathol (2012) 1.37
Hepatitis B virus X protein-induced aberrant epigenetic modifications contributing to human hepatocellular carcinoma pathogenesis. Mol Cell Biol (2013) 1.10
Adeno-associated virus-mediated gene transfer leads to persistent hepatitis B virus replication in mice expressing HLA-A2 and HLA-DR1 molecules. J Virol (2013) 1.03
Regulation of hepatitis B virus replication by epigenetic mechanisms and microRNAs. Front Genet (2013) 0.99
The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1. PLoS Pathog (2014) 0.96
Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription. J Virol (2013) 0.89
LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis. Mol Cell Biol (2013) 0.87
HBx induced AFP receptor expressed to activate PI3K/AKT signal to promote expression of Src in liver cells and hepatoma cells. BMC Cancer (2015) 0.83
Somatic mutations, viral integration and epigenetic modification in the evolution of hepatitis B virus-induced hepatocellular carcinoma. Curr Genomics (2014) 0.82
Role and functional domain of hepatitis B virus X protein in regulating HBV transcription and replication in vitro and in vivo. Viruses (2013) 0.82
Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling. PLoS Pathog (2015) 0.81
Requirement of CRTC1 coactivator for hepatitis B virus transcription. Nucleic Acids Res (2014) 0.81
Single-Nucleotide Resolution Mapping of Hepatitis B Virus Promoters in Infected Human Livers and Hepatocellular Carcinoma. J Virol (2016) 0.76
Genome-wide identification of direct HBx genomic targets. BMC Genomics (2017) 0.75
Protein Phosphatases Involved in Regulating Mitosis: Facts and Hypotheses. Mol Cells (2016) 0.75
Protein Phosphatase-1 regulates Rift Valley fever virus replication. Antiviral Res (2016) 0.75
Protein phosphatase 1 abrogates IRF7-mediated type I IFN response in antiviral immunity. Eur J Immunol (2016) 0.75
The human SWI/SNF subunit Brm is a regulator of alternative splicing. Nat Struct Mol Biol (2005) 6.60
Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway. Nat Cell Biol (2008) 4.68
Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function. Cell (2004) 3.73
SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells. Retrovirology (2007) 3.51
Statements from the Taormina expert meeting on occult hepatitis B virus infection. J Hepatol (2008) 3.50
An injected bacterial effector targets chromatin access for transcription factor NF-kappaB to alter transcription of host genes involved in immune responses. Nat Immunol (2006) 3.41
TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. Cancer Cell (2010) 3.25
Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer. Proc Natl Acad Sci U S A (2010) 2.91
Reprogramming of miRNA networks in cancer and leukemia. Genome Res (2010) 2.65
Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair. Genome Res (2013) 2.60
Infectious agents and cancer: criteria for a causal relation. Semin Cancer Biol (2004) 2.20
SWI/SNF chromatin remodeling and cancer. Curr Opin Genet Dev (2002) 2.00
Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction. Mol Cell Biol (2004) 1.95
Splicing, transcription, and chromatin: a ménage à trois. Curr Opin Genet Dev (2008) 1.92
Histone H3 lysine 9 trimethylation and HP1γ favor inclusion of alternative exons. Nat Struct Mol Biol (2011) 1.86
Histone modifications induced by a family of bacterial toxins. Proc Natl Acad Sci U S A (2007) 1.86
Argonaute proteins couple chromatin silencing to alternative splicing. Nat Struct Mol Biol (2012) 1.80
Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer. Cancer Cell (2008) 1.70
SWI/SNF chromatin-remodeling factors induce changes in DNA methylation to promote transcriptional activation. Cancer Res (2005) 1.68
Identification of the LIM protein FHL2 as a coactivator of beta-catenin. J Biol Chem (2002) 1.61
HBV induced carcinogenesis. J Clin Virol (2005) 1.56
Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer. Cancer Res (2007) 1.56
Altered expression of E-cadherin in hepatocellular carcinoma: correlations with genetic alterations, beta-catenin expression, and clinical features. Hepatology (2002) 1.55
Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3. EMBO Rep (2004) 1.48
SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity. Mol Biol Cell (2009) 1.41
Characterization of the early steps of infection of primary blood monocytes by human immunodeficiency virus type 1. J Virol (2008) 1.41
Transcriptional activation of interleukin-8 by beta-catenin-Tcf4. J Biol Chem (2002) 1.40
Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-catenin. Mol Cell Biol (2004) 1.37
A novel histone exchange factor, protein phosphatase 2Cgamma, mediates the exchange and dephosphorylation of H2A-H2B. J Cell Biol (2006) 1.34
Regulation of an inducible promoter by an HP1beta-HP1gamma switch. EMBO Rep (2008) 1.33
Hepatitis B virus X protein molecular functions and its role in virus life cycle and pathogenesis. Adv Cancer Res (2009) 1.32
The hepatitis B virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription. J Biol Chem (2006) 1.28
Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65). PLoS One (2007) 1.28
The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation. Genes Dev (2009) 1.24
The SWI/SNF chromatin-remodeling complex subunit SNF5 is essential for hepatocyte differentiation. EMBO J (2005) 1.23
The SWI/SNF ATPase Brm is a gatekeeper of proliferative control in prostate cancer. Cancer Res (2008) 1.21
Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression. PLoS Genet (2009) 1.19
Roles of Brahma and Brahma/SWI2-related gene 1 in hypoxic induction of the erythropoietin gene. J Biol Chem (2004) 1.19
Cyclin A repression in quiescent cells is associated with chromatin remodeling of its promoter and requires Brahma/SNF2alpha. Mol Cell (2004) 1.16
SNR1 is an essential subunit in a subset of Drosophila brm complexes, targeting specific functions during development. Dev Biol (2003) 1.15
The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver. Oncogene (2002) 1.13
Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia. Hum Mol Genet (2009) 1.11
Growth inhibition by the mammalian SWI-SNF subunit Brm is regulated by acetylation. EMBO J (2003) 1.10
An in vivo replication-important function in the second coding exon of Tat is constrained against mutation despite cytotoxic T lymphocyte selection. J Biol Chem (2003) 1.09
Coregulators: transducing signal from transcription to alternative splicing. Trends Endocrinol Metab (2007) 1.09
Anthrax lethal toxin impairs IL-8 expression in epithelial cells through inhibition of histone H3 modification. PLoS Pathog (2009) 1.04
Citrullination of histone H3 interferes with HP1-mediated transcriptional repression. PLoS Genet (2012) 1.04
Adeno-associated virus-mediated gene transfer leads to persistent hepatitis B virus replication in mice expressing HLA-A2 and HLA-DR1 molecules. J Virol (2013) 1.03
Arginine methylation controls the subcellular localization and functions of the oncoprotein splicing factor SF2/ASF. Mol Cell Biol (2010) 1.03
Integration of woodchuck hepatitis and N-myc rearrangement determine size and histologic grade of hepatic tumors. Hepatology (2004) 1.02
The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation. J Biol Chem (2008) 0.98
Human BAHD1 promotes heterochromatic gene silencing. Proc Natl Acad Sci U S A (2009) 0.98
Role for Brm in cell growth control. Cancer Res (2006) 0.97
Systematic identification of proteins binding to chromatin-embedded ubiquitylated H2B reveals recruitment of SWI/SNF to regulate transcription. Cell Rep (2013) 0.94
Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins. J Cell Biol (2014) 0.94
Polo-like kinase 1 inhibition suppresses hepatitis B virus X protein-induced transformation in an in vitro model of liver cancer progression. Hepatology (2009) 0.92
S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration. Proc Natl Acad Sci U S A (2013) 0.91
Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo. Blood (2010) 0.89
Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription. J Virol (2013) 0.89
The absence of Brm exacerbates photocarcinogenesis. Exp Dermatol (2012) 0.88
Diverse roles of hepatitis B virus in liver cancer. Curr Opin Virol (2012) 0.87
LIM-only protein FHL2 activates NF-κB signaling in the control of liver regeneration and hepatocarcinogenesis. Mol Cell Biol (2013) 0.87
Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses. J Biomed Sci (2012) 0.86
Characterization of the calcium binding protein family in zebrafish. PLoS One (2013) 0.84
The four and a half LIM-only protein 2 regulates liver homeostasis and contributes to carcinogenesis. J Hepatol (2012) 0.84
Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice. PLoS One (2010) 0.82
The win locus involved in activation of the distal N-myc2 gene upon WHV integration in woodchuck liver tumors harbors S/MAR elements. Virology (2004) 0.82
Immunogenic HLA-B*0702-restricted epitopes derived from human telomerase reverse transcriptase that elicit antitumor cytotoxic T-cell responses. Clin Cancer Res (2006) 0.82
The four and a half LIM-only protein 2 (FHL2) activates transforming growth factor β (TGF-β) signaling by regulating ubiquitination of the E3 ligase Arkadia. J Biol Chem (2012) 0.81
A novel Plasmodium falciparum SR protein is an alternative splicing factor required for the parasites' proliferation in human erythrocytes. Nucleic Acids Res (2012) 0.81
10-million-years AGO: argonaute on chromatin in yeast and human, a conserved mode of action? Transcription (2013) 0.78
The LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways. PLoS One (2008) 0.77
Liver cell transformation in chronic HBV infection. Viruses (2009) 0.76
Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress. Carcinogenesis (2015) 0.75
A few thoughts about catalyzing transcription. Epigenomics (2010) 0.75