Published in Science on January 05, 2012
A-to-I RNA editing: effects on proteins key to neural excitability. Neuron (2012) 1.52
The ADAR protein family. Genome Biol (2012) 1.39
Mammalian conserved ADAR targets comprise only a small fragment of the human editosome. Genome Biol (2014) 1.26
Voltage-gated potassium channels and the diversity of electrical signalling. J Physiol (2012) 1.22
Targeting potassium channels in cancer. J Cell Biol (2014) 1.15
The majority of transcripts in the squid nervous system are extensively recoded by A-to-I RNA editing. Elife (2015) 0.95
Analysis and design of RNA sequencing experiments for identifying RNA editing and other single-nucleotide variants. RNA (2013) 0.92
Many parameter sets in a multicompartment model oscillator are robust to temperature perturbations. J Neurosci (2014) 0.91
Dark matter RNA: an intelligent scaffold for the dynamic regulation of the nuclear information landscape. Front Genet (2012) 0.88
Comparative RNA editing in autistic and neurotypical cerebella. Mol Psychiatry (2012) 0.88
A role for A-to-I RNA editing in temperature adaptation. Physiology (Bethesda) (2012) 0.87
Dynamic response of RNA editing to temperature in Drosophila. BMC Biol (2015) 0.87
Novel RNA regulatory mechanisms revealed in the epitranscriptome. RNA Biol (2013) 0.86
Alternative applications for distinct RNA sequencing strategies. Brief Bioinform (2014) 0.85
Conduits of life's spark: a perspective on ion channel research since the birth of neuron. Neuron (2013) 0.84
Caste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior. Nat Commun (2014) 0.83
Using multiplex single-base extension typing to screen for mutants defective in RNA editing. Nat Protoc (2012) 0.83
Reciprocal regulation of A-to-I RNA editing and the vertebrate nervous system. Front Neurosci (2013) 0.83
From the ultrasonic to the infrared: molecular evolution and the sensory biology of bats. Front Physiol (2013) 0.83
The emerging role of RNA editing in plasticity. J Exp Biol (2015) 0.83
Cephalopod genomics: A plan of strategies and organization. Stand Genomic Sci (2012) 0.83
Genome-wide A-to-I RNA editing in fungi independent of ADAR enzymes. Genome Res (2016) 0.82
Blue blood on ice: modulated blood oxygen transport facilitates cold compensation and eurythermy in an Antarctic octopod. Front Zool (2015) 0.82
RNA editing in eag potassium channels: biophysical consequences of editing a conserved S6 residue. Channels (Austin) (2012) 0.82
New Insights into the Biological Role of Mammalian ADARs; the RNA Editing Proteins. Biomolecules (2015) 0.81
Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes. PeerJ (2013) 0.79
The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection. PLoS Genet (2016) 0.79
Regulation of Ion Channel and Transporter Function Through RNA Editing. Curr Issues Mol Biol (2014) 0.77
Parallel Evolution and Lineage-Specific Expansion of RNA Editing in Ctenophores. Integr Comp Biol (2015) 0.77
RBP-Var: a database of functional variants involved in regulation mediated by RNA-binding proteins. Nucleic Acids Res (2015) 0.76
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats. Mol Biol Evol (2016) 0.75
Discriminative Prediction of A-To-I RNA Editing Events from DNA Sequence. PLoS One (2016) 0.75
RNA-DNA sequence differences in Saccharomyces cerevisiae. Genome Res (2016) 0.75
Condition-specific RNA editing in the coral symbiont Symbiodinium microadriaticum. PLoS Genet (2017) 0.75
Biochemistry. A cold editor makes the adaptation. Science (2012) 0.75
Transcriptomic changes in an animal-bacterial symbiosis under modeled microgravity conditions. Sci Rep (2017) 0.75
RNA editing differently affects protein-coding genes in D. melanogaster and H. sapiens. Sci Rep (2015) 0.75
Adaptation of A-to-I RNA editing in Drosophila. PLoS Genet (2017) 0.75
Transcriptomic changes in brain development. Int Rev Neurobiol (2014) 0.75
A-to-I RNA editing is developmentally regulated and generally adaptive for sexual reproduction in Neurospora crassa. Proc Natl Acad Sci U S A (2017) 0.75
ADAR RNA editing below the backbone. RNA (2017) 0.75
Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo. J Physiol (1952) 137.36
The effect of temperature on the electrical activity of the giant axon of the squid. J Physiol (1949) 66.32
Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science (2005) 17.70
Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature (2007) 12.35
The developmental transcriptome of Drosophila melanogaster. Nature (2010) 11.85
Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs. Neuron (1992) 10.25
Destruction of sodium conductance inactivation in squid axons perfused with pronase. J Gen Physiol (1973) 8.53
Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature (1997) 7.92
An unwinding activity that covalently modifies its double-stranded RNA substrate. Cell (1988) 5.93
Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science (1994) 5.21
Single channel recordings of K+ currents in squid axons. Nature (1980) 4.48
Novel voltage clamp to record small, fast currents from ion channels expressed in Xenopus oocytes. Biophys J (1992) 3.75
Specification of subunit assembly by the hydrophilic amino-terminal domain of the Shaker potassium channel. Science (1992) 3.53
Closing in on the resting state of the Shaker K(+) channel. Neuron (2007) 3.49
Coupling between voltage sensors and activation gate in voltage-gated K+ channels. J Gen Physiol (2002) 3.16
Crystal structure of the tetramerization domain of the Shaker potassium channel. Nature (1998) 2.56
Functional interactions at the interface between voltage-sensing and pore domains in the Shaker K(v) channel. Neuron (2006) 2.25
Control of human potassium channel inactivation by editing of a small mRNA hairpin. Nat Struct Mol Biol (2004) 2.25
Maximum likelihood estimation of ion channel kinetics from macroscopic currents. Biophys J (2005) 2.18
Synthetic polynucleotides and the amino acid code. V. Proc Natl Acad Sci U S A (1962) 2.01
The polar T1 interface is linked to conformational changes that open the voltage-gated potassium channel. Cell (2000) 1.90
RNA editing generates a diverse array of transcripts encoding squid Kv2 K+ channels with altered functional properties. Neuron (1997) 1.71
Voltage gating of Shaker K+ channels. The effect of temperature on ionic and gating currents. J Gen Physiol (1998) 1.66
Hanging gondola structure of the T1 domain in a voltage-gated K(+) channel. Biochemistry (2000) 1.55
Impact of Antarctic Circumpolar Current development on late Paleogene ocean structure. Science (2011) 1.50
Potassium conductance of the squid giant axon. Single-channel studies. J Gen Physiol (1988) 1.38
Editing of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR-B pre-mRNA in vitro reveals site-selective adenosine to inosine conversion. J Biol Chem (1995) 1.34
Extensive editing of mRNAs for the squid delayed rectifier K+ channel regulates subunit tetramerization. Neuron (2002) 1.33
Voltage dependent activation of potassium channels is coupled to T1 domain structure. Nat Struct Biol (2000) 1.29
Model-based fitting of single-channel dwell-time distributions. Biophys J (2004) 1.13
Properties of sodium and potassium channels of the squid giant axon far below 0 degrees C. J Membr Biol (1982) 1.00
Molecular identification of SqKv1A. A candidate for the delayed rectifier K channel in squid giant axon. J Gen Physiol (1996) 0.96
An accurate fluorescent assay for quantifying the extent of RNA editing. RNA (2006) 0.93
Control of human potassium channel inactivation by editing of a small mRNA hairpin. Nat Struct Mol Biol (2004) 2.25
An extra double-stranded RNA binding domain confers high activity to a squid RNA editing enzyme. RNA (2009) 1.00
Structural basis of Na(+)/K(+)-ATPase adaptation to marine environments. Nat Struct Mol Biol (2007) 0.98
Editing of human K(V)1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity. Nat Commun (2011) 0.98
Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways. J Neurochem (2005) 0.95
Regulation of Na+/K+ ATPase transport velocity by RNA editing. PLoS Biol (2010) 0.94
An accurate fluorescent assay for quantifying the extent of RNA editing. RNA (2006) 0.93
Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects. Nucleic Acids Res (2011) 0.93
A role for A-to-I RNA editing in temperature adaptation. Physiology (Bethesda) (2012) 0.87
Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squid. Proc Natl Acad Sci U S A (2011) 0.87
Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing. Proc Natl Acad Sci U S A (2013) 0.85
Extra double-stranded RNA binding domain (dsRBD) in a squid RNA editing enzyme confers resistance to high salt environment. J Biol Chem (2012) 0.83
Cephalopod genomics: A plan of strategies and organization. Stand Genomic Sci (2012) 0.83
Physiological adaptation of an Antarctic Na+/K+-ATPase to the cold. J Exp Biol (2011) 0.80
Regulation of Ion Channel and Transporter Function Through RNA Editing. Curr Issues Mol Biol (2014) 0.77
Temperature compensation of aerobic capacity and performance in the Antarctic pteropod, Clione antarctica, compared with its northern congener, C. limacina. J Exp Biol (2012) 0.76