Published in J Chem Biol on January 08, 2011
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Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide. Br J Biomed Sci (2010) 0.94
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Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells. Biomed Sci Instrum (2006) 0.83
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Effect of thymoquinone on mouse dendritic cells. Cell Physiol Biochem (2010) 0.82
The physiological effect of conventional treatment with epigallocatechin-3-gallate, thymoquinone, and tannic acid on the LNCaP cell line. Biomed Sci Instrum (2006) 0.81
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A comparison of the morphological changes associated with conventional and sustained treatment with pigallocatechin3gallate, thymoquinone, and tannic acid on lncap cells. Biomed Sci Instrum (2008) 0.79
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Applying linear and non-linear methods for parallel prediction of volume of distribution and fraction of unbound drug. PLoS One (2013) 1.43
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5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms. J Pharmacol Exp Ther (2004) 1.27
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Lack of p53 augments thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells. Cancer Biol Ther (2007) 1.23
Reactive oxygen species mediate thymoquinone-induced apoptosis and activate ERK and JNK signaling. Apoptosis (2010) 1.21
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Targeting hypoxia for sensitization of tumors to radio- and chemotherapy. Curr Cancer Drug Targets (2013) 1.17
Three-dimensional structures of thermophilic beta-1,4-xylanases from Chaetomium thermophilum and Nonomuraea flexuosa. Comparison of twelve xylanases in relation to their thermal stability. Eur J Biochem (2003) 1.15
Influence of tamsulosin on the iris and its implications for cataract surgery. Invest Ophthalmol Vis Sci (2006) 1.15
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Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models. J Cell Mol Med (2008) 1.10
Transscleral drug delivery to the posterior eye: prospects of pharmacokinetic modeling. Adv Drug Deliv Rev (2006) 1.09
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Structure-activity relationships of poly(L-lysines): effects of pegylation and molecular shape on physicochemical and biological properties in gene delivery. J Control Release (2002) 1.07
Crystal structure of uronate dehydrogenase from Agrobacterium tumefaciens. J Biol Chem (2011) 1.06
Computing positional isotopomer distributions from tandem mass spectrometric data. Metab Eng (2002) 1.06
The effect and role of carbon atoms in poly(β-amino ester)s for DNA binding and gene delivery. J Am Chem Soc (2013) 1.06
Determination of tamsulosin in human aqueous humor and serum by liquid chromatography-electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal (2006) 1.05
Preclinical evaluation of rapeseed, raspberry, and pine bark phenolics for health related effects. J Agric Food Chem (2005) 1.03
Interfacing an aspiration ion mobility spectrometer to a triple quadrupole mass spectrometer. Rev Sci Instrum (2007) 1.02
Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family. Biochem J (2007) 1.00
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DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides. Mol Cell Biol (2008) 0.99
Extracellular and intracellular barriers in non-viral gene delivery. J Control Release (2003) 0.97
Efflux protein expression in human retinal pigment epithelium cell lines. Pharm Res (2009) 0.97
Analysis of acetylcholine and choline in microdialysis samples by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom (2005) 0.96
Overview of major classes of plant-derived anticancer drugs. Int J Biomed Sci (2009) 0.96
Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity. Eur J Pharm Sci (2004) 0.96
Alginate-based microencapsulation of retinal pigment epithelial cell line for cell therapy. Biomaterials (2007) 0.95
Dehydration studies using a novel multichamber microscale fluid bed dryer with in-line near-infrared measurement. J Pharm Sci (2003) 0.95
p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells. Mol Vis (2010) 0.95
Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer. J Gene Med (2004) 0.95
Computational prediction of oral drug absorption based on absorption rate constants in humans. J Med Chem (2006) 0.94
Effluxing ABC transporters in human corneal epithelium. J Pharm Sci (2010) 0.93
Microchip technology in mass spectrometry. Mass Spectrom Rev (2010) 0.92
Effect of glycosylation and additional domains on the thermostability of a family 10 xylanase produced by Thermopolyspora flexuosa. Appl Environ Microbiol (2009) 0.92
Desorption electrospray ionization mass spectrometry for the analysis of pharmaceuticals and metabolites. Rapid Commun Mass Spectrom (2006) 0.92
Transient dimers of allergens. PLoS One (2010) 0.92
Gold-embedded photosensitive liposomes for drug delivery: triggering mechanism and intracellular release. J Control Release (2010) 0.91
Comparison of rat epidermal keratinocyte organotypic culture (ROC) with intact human skin: lipid composition and thermal phase behavior of the stratum corneum. Biochim Biophys Acta (2008) 0.91
Vitreous is a barrier in nonviral gene transfer by cationic lipids and polymers. Pharm Res (2003) 0.90
Regulation of the human tyrosinase gene in retinal pigment epithelium cells: the significance of transcription factor orthodenticle homeobox 2 and its polymorphic binding site. Mol Vis (2012) 0.90
Analysis of small molecules by ultra thin-layer chromatography-atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry. J Am Soc Mass Spectrom (2005) 0.90
Mechanisms of polyethylenimine-mediated DNA delivery: free carrier helps to overcome the barrier of cell-surface glycosaminoglycans. J Gene Med (2011) 0.90
Barrier analysis of periocular drug delivery to the posterior segment. J Control Release (2010) 0.90
Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G₂ checkpoint arrest. J Cell Mol Med (2011) 0.89
Bradavidin II from Bradyrhizobium japonicum: a new avidin-like biotin-binding protein. Biochim Biophys Acta (2008) 0.89
Desorption atmospheric pressure photoionization. Anal Chem (2007) 0.88
HPLC micro-fractionation coupled to a cell-based assay for automated on-line primary screening of calcium antagonistic components in plant extracts. Anal Bioanal Chem (2004) 0.88
Precisely defined protein-polymer conjugates: construction of synthetic DNA binding domains on proteins by using multivalent dendrons. ACS Nano (2007) 0.88
Simultaneous analysis of prostanoids using liquid chromatography/high-field asymmetric waveform ion mobility spectrometry/tandem mass spectrometry. Rapid Commun Mass Spectrom (2006) 0.88
DUSP5 and DUSP6 modulate corneal epithelial cell proliferation. Mol Vis (2010) 0.88
Simultaneous determination of eight beta-blockers by gradient high-performance liquid chromatography with combined ultraviolet and fluorescence detection in corneal permeability studies in vitro. J Chromatogr B Analyt Technol Biomed Life Sci (2002) 0.88
Polyplex-mediated gene transfer and cell cycle: effect of carrier on cellular uptake and intracellular kinetics, and significance of glycosaminoglycans. J Gene Med (2007) 0.88
Paracellular porosity and pore size of the human intestinal epithelium in tissue and cell culture models. J Pharm Sci (2010) 0.87
Analysis of intact glucuronides and sulfates of serotonin, dopamine, and their phase I metabolites in rat brain microdialysates by liquid chromatography-tandem mass spectrometry. Anal Chem (2009) 0.87
Protective effect of vitamin E on ultraviolet B light-induced damage in keratinocytes. Mol Carcinog (2002) 0.87
Freeze-drying of cationic polymer DNA complexes enables their long-term storage and reverse transfection of post-mitotic cells. J Control Release (2005) 0.87
A de novo designed N-terminal disulphide bridge stabilizes the Trichoderma reesei endo-1,4-beta-xylanase II. J Biotechnol (2004) 0.87
Rational modification of ligand-binding preference of avidin by circular permutation and mutagenesis. Chembiochem (2008) 0.87
Evidence for conserved function of γ-glutamyltranspeptidase in Helicobacter genus. PLoS One (2012) 0.87
Generation of hESC-derived retinal pigment epithelium on biopolymer coated polyimide membranes. Biomaterials (2012) 0.87
Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells. Radiat Oncol (2007) 0.87
'All-in-one' analysis for metabolite identification using liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry with collision energy switching. Rapid Commun Mass Spectrom (2005) 0.87
Inhibition of tumor promotion by parthenolide: epigenetic modulation of p21. Cancer Prev Res (Phila) (2012) 0.87
Binding of betaxolol, metoprolol and oligonucleotides to synthetic and bovine ocular melanin, and prediction of drug binding to melanin in human choroid-retinal pigment epithelium. Pharm Res (2007) 0.87
Radiosensitization of EMT6 mammary carcinoma cells by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide. Radiother Oncol (2007) 0.87
Permeability characteristics and membrane affinity of flavonoids and alkyl gallates in Caco-2 cells and in phospholipid vesicles. Arch Biochem Biophys (2004) 0.87
Characterization of the in vitro metabolic profile of amlodipine in rat using liquid chromatography-mass spectrometry. Eur J Pharm Sci (2007) 0.87
Fully microfabricated and integrated SU-8-based capillary electrophoresis-electrospray ionization microchips for mass spectrometry. Anal Chem (2007) 0.86
Gallotannin inhibits NFĸB signaling and growth of human colon cancer xenografts. Cancer Biol Ther (2011) 0.86
Dioleoyl phosphatidylethanolamine and PEG-lipid conjugates modify DNA delivery mediated by 1,4-dihydropyridine amphiphiles. J Control Release (2004) 0.86
High-throughput screening of cell responses to biomaterials. Eur J Pharm Sci (2008) 0.86
Comparison of different amino acid derivatives and analysis of rat brain microdialysates by liquid chromatography tandem mass spectrometry. Anal Chim Acta (2008) 0.86
Evaluation of novel starch acetate-diltiazem controlled release tablets in healthy human volunteers. J Control Release (2004) 0.85
Nanofibrillar cellulose hydrogel promotes three-dimensional liver cell culture. J Control Release (2012) 0.85
Pre-targeting and direct immunotargeting of liposomal drug carriers to ovarian carcinoma. PLoS One (2012) 0.85
Determination of Serotonin and Dopamine Metabolites in Human Brain Microdialysis and Cerebrospinal Fluid Samples by UPLC-MS/MS: Discovery of Intact Glucuronide and Sulfate Conjugates. PLoS One (2013) 0.85
Role of polyplex intermediate species on gene transfer efficiency: polyethylenimine-DNA complexes and time-resolved fluorescence spectroscopy. J Phys Chem B (2011) 0.85
Time-resolved fluorescence spectroscopy reveals functional differences of cationic polymer-DNA complexes. J Am Chem Soc (2008) 0.85
Feasibility of using atmospheric pressure matrix-assisted laser desorption/ionization with ion trap mass spectrometry in the analysis of acetylated xylooligosaccharides derived from hardwoods and Arabidopsis thaliana. Anal Bioanal Chem (2011) 0.85
Alpha terpineol: a potential anticancer agent which acts through suppressing NF-kappaB signalling. Anticancer Res (2010) 0.85
Effect of cell differentiation and passage number on the expression of efflux proteins in wild type and vinblastine-induced Caco-2 cell lines. Eur J Pharm Biopharm (2007) 0.85
Isolation and identification of oligomeric procyanidins from Crataegus leaves and flowers. Phytochemistry (2002) 0.85
The role of cell cycle on polyplex-mediated gene transfer into a retinal pigment epithelial cell line. J Gene Med (2005) 0.85
In vivo treatment of acute Chlamydia pneumoniae infection with the flavonoids quercetin and luteolin and an alkyl gallate, octyl gallate, in a mouse model. Biochem Pharmacol (2005) 0.84