Published in Int J Radiat Biol on March 01, 2012
Radiation dose-rate effects on gene expression for human biodosimetry. BMC Med Genomics (2015) 0.88
A network-based method to assess the statistical significance of mild co-regulation effects. PLoS One (2013) 0.86
Toward the development of transcriptional biodosimetry for the identification of irradiated individuals and assessment of absorbed radiation dose. Radiat Environ Biophys (2015) 0.83
MicroRNA Expression for Early Prediction of Late Occurring Hematologic Acute Radiation Syndrome in Baboons. PLoS One (2016) 0.82
Effect of irradiation on the expression of DNA repair genes studied in human fibroblasts by real-time qPCR using three methods of reference gene validation. Radiat Environ Biophys (2013) 0.81
Radiation-induced alternative transcription and splicing events and their applicability to practical biodosimetry. Sci Rep (2016) 0.78
GDF-15 gene expression alterations in human lymphoblastoid cells and peripheral blood lymphocytes following exposure to ionizing radiation. Mol Med Rep (2017) 0.75
Radiation Metabolomics: Current Status and Future Directions. Front Oncol (2016) 0.75
Dose-Response Curves of the FDXR and RAD51 Genes with 6 and 18 MV Beam Energies in Human Peripheral Blood Lymphocytes. Iran Red Crescent Med J (2016) 0.75
Do simple models lead to generality in ecology? Trends Ecol Evol (2013) 2.88
Systems medicine and integrated care to combat chronic noncommunicable diseases. Genome Med (2011) 1.78
Minimum Information About a Simulation Experiment (MIASE). PLoS Comput Biol (2011) 1.48
Investigations into the analysis and modeling of the TNF alpha-mediated NF-kappa B-signaling pathway. Genome Res (2003) 1.12
Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease. EMBO J (2011) 1.10
Optimal sampling time selection for parameter estimation in dynamic pathway modeling. Biosystems (2004) 1.08
Analysing the impact of nucleo-cytoplasmic shuttling of β-catenin and its antagonists APC, Axin and GSK3 on Wnt/β-catenin signalling. Cell Signal (2013) 1.02
Mathematical modelling of interferon-gamma signalling in pancreatic stellate cells reflects and predicts the dynamics of STAT1 pathway activity. Cell Signal (2009) 1.02
Computational analysis of target hub gene repression regulated by multiple and cooperative miRNAs. Nucleic Acids Res (2012) 1.00
Kinetic modeling-based detection of genetic signatures that provide chemoresistance via the E2F1-p73/DNp73-miR-205 network. Cancer Res (2013) 0.98
MicroRNA-mRNA interactions in colorectal cancer and their role in tumor progression. Genes Chromosomes Cancer (2015) 0.97
Systems biology of JAK-STAT signalling in human malignancies. Prog Biophys Mol Biol (2011) 0.96
Gene expression in low- and high-dose-irradiated human peripheral blood lymphocytes: possible applications for biodosimetry. Radiat Res (2012) 0.94
A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture. BMC Syst Biol (2011) 0.93
Approximations and their consequences for dynamic modelling of signal transduction pathways. Math Biosci (2006) 0.93
Microarray data clustering based on temporal variation: FCV with TSD preclustering. Appl Bioinformatics (2003) 0.93
Switching feedback mechanisms realize the dual role of MCIP in the regulation of calcineurin activity. FEBS Lett (2006) 0.92
Oxidative stress-induced cytotoxic and genotoxic effects of nano-sized titanium dioxide particles in human HaCaT keratinocytes. Toxicology (2012) 0.91
The multikinase inhibitor Sorafenib displays significant antiproliferative effects and induces apoptosis via caspase 3, 7 and PARP in B- and T-lymphoblastic cells. BMC Cancer (2010) 0.91
Studies on mechanisms of interferon-gamma action in pancreatic cancer using a data-driven and model-based approach. Mol Cancer (2011) 0.91
Dynamic energy budget approaches for modelling organismal ageing. Philos Trans R Soc Lond B Biol Sci (2010) 0.89
Power-law models of signal transduction pathways. Cell Signal (2007) 0.89
In vivo versus in vitro individual radiosensitivity analysed in healthy donors and in prostate cancer patients with and without severe side effects after radiotherapy. Int J Radiat Biol (2012) 0.89
2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells. Proteomics (2007) 0.89
Investigating dynamics of inhibitory and feedback loops in ERK signalling using power-law models. Mol Biosyst (2010) 0.89
Improving the reuse of computational models through version control. Bioinformatics (2013) 0.89
Clinico-pathologic function of cerebral ABC transporters - implications for the pathogenesis of Alzheimer's disease. Curr Alzheimer Res (2008) 0.88
Dynamics of biological systems: role of systems biology in medical research. Expert Rev Mol Diagn (2006) 0.88
SBML export interface for the systems biology toolbox for MATLAB. Bioinformatics (2007) 0.87
How Modeling Standards, Software, and Initiatives Support Reproducibility in Systems Biology and Systems Medicine. IEEE Trans Biomed Eng (2016) 0.87
A shift in the dominant phenotype governs the pH-induced metabolic switch of Clostridium acetobutylicumin phosphate-limited continuous cultures. Appl Microbiol Biotechnol (2013) 0.86
A systems biology approach to analyse amplification in the JAK2-STAT5 signalling pathway. BMC Syst Biol (2008) 0.86
Non-coding RNA detection methods combined to improve usability, reproducibility and precision. BMC Bioinformatics (2010) 0.86
Identification of immunogenic consensus T-cell epitopes in globally distributed influenza-A H1N1 neuraminidase. Infect Genet Evol (2010) 0.86
A unified framework for unraveling the functional interaction structure of a biomolecular network based on stimulus-response experimental data. FEBS Lett (2005) 0.86
MicroRNA-regulated networks: the perfect storm for classical molecular biology, the ideal scenario for systems biology. Adv Exp Med Biol (2013) 0.86
Parameter identifiability and sensitivity analysis predict targets for enhancement of STAT1 activity in pancreatic cancer and stellate cells. PLoS Comput Biol (2012) 0.86
Association of RHAMM with E2F1 promotes tumour cell extravasation by transcriptional up-regulation of fibronectin. J Pathol (2014) 0.85
PLMaddon: a power-law module for the Matlab SBToolbox. Bioinformatics (2007) 0.85
Modeling miRNA regulation in cancer signaling systems: miR-34a regulation of the p53/Sirt1 signaling module. Methods Mol Biol (2012) 0.84
Intracellular delay limits cyclic changes in gene expression. Math Biosci (2006) 0.84
Modeling the Calvin-Benson cycle. BMC Syst Biol (2011) 0.84
Report on EU-USA workshop: how systems biology can advance cancer research (27 October 2008). Mol Oncol (2008) 0.84
Dynamical effects of epigenetic silencing of 14-3-3sigma expression. Mol Biosyst (2009) 0.83
Coenzyme A-transferase-independent butyrate re-assimilation in Clostridium acetobutylicum-evidence from a mathematical model. Appl Microbiol Biotechnol (2014) 0.83
Analysis of DNA microarray data. Curr Top Med Chem (2004) 0.83
A mathematical analysis of nuclear intensity dynamics for Mig1-GFP under consideration of bleaching effects and background noise in Saccharomyces cerevisiae. Mol Biosyst (2010) 0.83
Transcriptome alterations in zebrafish embryos after exposure to environmental estrogens and anti-androgens can reveal endocrine disruption. Reprod Toxicol (2013) 0.82
Integration in action. EMBO Rep (2012) 0.82
Inbred mouse strains reveal biomarkers that are pro-longevity, antilongevity or role switching. Aging Cell (2014) 0.82
How mathematical modelling elucidates signalling in Bacillus subtilis. Mol Microbiol (2010) 0.82
Stochastic approaches in systems biology. Wiley Interdiscip Rev Syst Biol Med (2010) 0.82
Glucose de-repression by yeast AMP-activated protein kinase SNF1 is controlled via at least two independent steps. FEBS J (2014) 0.81
Glycogen synthase kinase-3beta regulates differentiation-induced apoptosis of human neural progenitor cells. Int J Dev Neurosci (2012) 0.81
Phosphoglycerate mutases function as reverse regulated isoenzymes in Synechococcus elongatus PCC 7942. PLoS One (2013) 0.81
Multi-compartmental modeling of SORLA's influence on amyloidogenic processing in Alzheimer's disease. BMC Syst Biol (2012) 0.81
Influence of 50 Hz electromagnetic fields in combination with a tumour promoting phorbol ester on protein kinase C and cell cycle in human cells. Mol Cell Biochem (2002) 0.81
Integrative modelling of pH-dependent enzyme activity and transcriptomic regulation of the acetone-butanol-ethanol fermentation of Clostridium acetobutylicum in continuous culture. Microb Biotechnol (2013) 0.81
Novel broad host range shuttle vectors for expression in Escherichia coli, Bacillus subtilis and Pseudomonas putida. J Biotechnol (2012) 0.81
Advanced significance analysis of microarray data based on weighted resampling: a comparative study and application to gene deletions in Mycobacterium bovis. Bioinformatics (2004) 0.80
Insights into erlotinib action in pancreatic cancer cells using a combined experimental and mathematical approach. World J Gastroenterol (2012) 0.80
Studying the effects of genistein on gene expression of fish embryos as an alternative testing approach for endocrine disruption. Comp Biochem Physiol C Toxicol Pharmacol (2012) 0.80
Dynamic properties of a delayed protein cross talk model. Biosystems (2007) 0.79
System approaches of Weiss and Bertalanffy and their relevance for systems biology today. Semin Cancer Biol (2011) 0.79
Simulations of stressosome activation emphasize allosteric interactions between RsbR and RsbT. BMC Syst Biol (2013) 0.79
Persisting ring chromosomes detected by mFISH in lymphocytes of a cancer patient-a case report. Mutat Res (2013) 0.79
Nucleo-cytoplasmic shuttling of APC can maximize β-catenin/TCF concentration. J Theor Biol (2011) 0.79
Tracing organizing principles: learning from the history of systems biology. Hist Philos Life Sci (2013) 0.79
A multi-level model accounting for the effects of JAK2-STAT5 signal modulation in erythropoiesis. Comput Biol Chem (2009) 0.78
A model-based strategy to investigate the role of microRNA regulation in cancer signalling networks. Theory Biosci (2010) 0.78
A hybrid systems framework for cellular processes. Biosystems (2005) 0.78
Systems biology to battle vascular disease. Nephrol Dial Transplant (2010) 0.78
The role of dynamic stimulation pattern in the analysis of bistable intracellular networks. Biosystems (2008) 0.78
A system biology approach to understand functional activity of cell communication systems. Methods Cell Biol (2008) 0.78
Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic. Biochim Biophys Acta (2013) 0.78
Alterations in the cell cycle and in the protein level of cyclin D1, p21CIP1, and p16INK4a after exposure to 50 Hz MF in human cells. Radiat Environ Biophys (2002) 0.77
Web resources for microRNA research. Adv Exp Med Biol (2013) 0.77
Principal difference between stability and structural stability (robustness) as used in systems biology. Nonlinear Dynamics Psychol Life Sci (2007) 0.77
The systems biology of mitochondrial fission and fusion and implications for disease and aging. Biogerontology (2014) 0.77
Thresholds in transient dynamics of signal transduction pathways. J Theor Biol (2010) 0.77
Investigating the two-moment characterisation of subcellular biochemical networks. J Theor Biol (2009) 0.76
Analysis of cell adhesion during early stages of colon cancer based on an extended multi-valued logic approach. Mol Biosyst (2012) 0.76
Tumors as chaotic attractors. Mol Biosyst (2014) 0.76
Proteolysis of beta-galactosidase following SigmaB activation in Bacillus subtilis. Mol Biosyst (2012) 0.76
The RNA world in the 21st century-a systems approach to finding non-coding keys to clinical questions. Brief Bioinform (2015) 0.76
Baccoside A suppresses epileptic-like seizure/convulsion in Caenorhabditis elegans. Seizure (2010) 0.76
Naïve Bayes classifier predicts functional microRNA target interactions in colorectal cancer. Mol Biosyst (2015) 0.76
How quantitative measures unravel design principles in multi-stage phosphorylation cascades. J Theor Biol (2008) 0.76
Modeling of cellular processes: methods, data, and requirements. Methods Mol Biol (2011) 0.76
Personalized cancer immunotherapy using Systems Medicine approaches. Brief Bioinform (2015) 0.76
Cytotoxic effects and specific gene expression alterations induced by I-125-labeled triplex-forming oligonucleotides. Int J Radiat Biol (2012) 0.76
Anti-inflammatory effects of reactive oxygen species - a multi-valued logical model validated by formal concept analysis. BMC Syst Biol (2014) 0.75
Dynamics of receptor and protein transducer homodimerisation. BMC Syst Biol (2008) 0.75
Systems biology and pediatric research. Pediatr Res (2013) 0.75
Information-theoretic analysis of protein sequences shows that amino acids self-cluster. J Theor Biol (2002) 0.75
Chromosomal radiosensitivity analyzed by FISH in lymphocytes of prostate cancer patients and healthy donors. Radiat Res (2013) 0.75
Systems biology approaches in aging research. Interdiscip Top Gerontol (2014) 0.75
The statistical distribution of the intensity of pixels within spots of DNA microarrays: what is the appropriate single-value representative? Appl Bioinformatics (2003) 0.75
Computational analysis and modeling the effectiveness of 'Zanamivir' targeting neuraminidase protein in pandemic H1N1 strains. Infect Genet Evol (2011) 0.75