Published in J Am Soc Nephrol on January 12, 2012
Proteinase 3 on apoptotic cells disrupts immune silencing in autoimmune vasculitis. J Clin Invest (2015) 1.43
How anti-neutrophil cytoplasmic autoantibodies activate neutrophils. Clin Exp Immunol (2012) 1.07
Inflammasome-independent IL-1β mediates autoinflammatory disease in Pstpip2-deficient mice. Proc Natl Acad Sci U S A (2014) 1.05
Localization and functionality of the inflammasome in neutrophils. J Biol Chem (2014) 1.00
Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition. PLoS Pathog (2016) 0.87
Of Inflammasomes and Alarmins: IL-1β and IL-1α in Kidney Disease. J Am Soc Nephrol (2016) 0.86
Reduced hind limb ischemia-reperfusion injury in Toll-like receptor-4 mutant mice is associated with decreased neutrophil extracellular traps. J Vasc Surg (2013) 0.82
The role of neutrophils and NETosis in autoimmune and renal diseases. Nat Rev Nephrol (2016) 0.82
Phagocyte NADPH oxidase restrains the inflammasome in ANCA-induced GN. J Am Soc Nephrol (2014) 0.82
Neutrophil Elastase Promotes Interleukin-1β Secretion from Human Coronary Endothelium. J Biol Chem (2015) 0.82
T cell-macrophage interactions and granuloma formation in vasculitis. Front Immunol (2014) 0.80
Intermediate monocytes in ANCA vasculitis: increased surface expression of ANCA autoantigens and IL-1β secretion in response to anti-MPO antibodies. Sci Rep (2015) 0.78
CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production. PLoS Pathog (2017) 0.78
Distinct contributions of interleukin-1α (IL-1α) and IL-1β to innate immune recognition of Pseudomonas aeruginosa in the lung. Infect Immun (2014) 0.78
Neutrophil serine proteases exert proteolytic activity on endothelial cells. Kidney Int (2015) 0.78
Neutrophil Extracellular Traps Enhance Early Inflammatory Response in Sendai Virus-Induced Asthma Phenotype. Front Immunol (2016) 0.75
Characterization of the CD177 interaction with the ANCA antigen proteinase 3. Sci Rep (2017) 0.75
Activation of proteinase 3 contributes to Non-alcoholic Fatty Liver Disease (NAFLD) and insulin resistance. Mol Med (2016) 0.75
Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice. PLoS One (2017) 0.75
The inflammasome NLRP3 plays a protective role against a viral immunopathological lesion. J Leukoc Biol (2015) 0.75
The Small Tellurium Compound AS101 Ameliorates Rat Crescentic Glomerulonephritis: Association with Inhibition of Macrophage Caspase-1 Activity via Very Late Antigen-4 Inactivation. Front Immunol (2017) 0.75
Neutrophils and Immunity: From Bactericidal Action to Being Conquered. J Immunol Res (2017) 0.75
Re-Examining Neutrophil Participation in GN. J Am Soc Nephrol (2017) 0.75
The inflammasomes: guardians of the body. Annu Rev Immunol (2009) 12.89
Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science (1995) 11.38
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes. Nature (1992) 9.96
Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med (1988) 8.01
Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature (2002) 7.53
Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc Natl Acad Sci U S A (1990) 7.19
Netting neutrophils in autoimmune small-vessel vasculitis. Nat Med (2009) 6.72
Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J Clin Invest (2002) 5.42
NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta. Cell (2007) 4.56
Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis. Nat Med (1998) 4.04
Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis. J Clin Invest (2002) 2.56
Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo. Proc Natl Acad Sci U S A (1999) 2.48
Converting enzyme-independent release of tumor necrosis factor alpha and IL-1beta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3. Proc Natl Acad Sci U S A (1999) 2.40
Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta. Arthritis Rheum (2009) 2.23
Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation. Arthritis Rheum (2009) 2.16
Degradation of outer membrane protein A in Escherichia coli killing by neutrophil elastase. Science (2000) 1.97
Processing of precursor interleukin 1 beta and inflammatory disease. J Biol Chem (1990) 1.94
C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis. J Am Soc Nephrol (2008) 1.92
Antineutrophil cytoplasm antibodies directed against myeloperoxidase augment leukocyte-microvascular interactions in vivo. Blood (2005) 1.86
Granzyme A is an interleukin 1 beta-converting enzyme. J Exp Med (1995) 1.81
Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase. J Exp Med (1991) 1.79
Aggravation of anti-myeloperoxidase antibody-induced glomerulonephritis by bacterial lipopolysaccharide: role of tumor necrosis factor-alpha. Am J Pathol (2005) 1.65
Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice. J Biol Chem (2001) 1.57
Normal neutrophil function in cathepsin G-deficient mice. Blood (1999) 1.53
Anti-neutrophil cytoplasmic antibodies and effector CD4+ cells play nonredundant roles in anti-myeloperoxidase crescentic glomerulonephritis. J Am Soc Nephrol (2006) 1.49
In situ production of TNF-alpha, IL-1 beta and IL-2R in ANCA-positive glomerulonephritis. Kidney Int (1993) 1.49
Crosslinking of ANCA-antigens stimulates superoxide release by human neutrophils. J Am Soc Nephrol (1997) 1.40
Autoinflammation: the prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses. J Allergy Clin Immunol (2009) 1.38
Bioactive proteinase 3 on the cell surface of human neutrophils: quantification, catalytic activity, and susceptibility to inhibition. J Immunol (2000) 1.38
Critical role of dipeptidyl peptidase I in neutrophil recruitment during the development of experimental abdominal aortic aneurysms. Proc Natl Acad Sci U S A (2007) 1.32
IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis. J Am Soc Nephrol (2010) 1.24
Bone marrow-derived cells are sufficient and necessary targets to mediate glomerulonephritis and vasculitis induced by anti-myeloperoxidase antibodies. J Am Soc Nephrol (2006) 1.20
Reactivity of antineutrophil cytoplasmic autoantibodies with mononuclear phagocytes. J Leukoc Biol (1992) 1.19
Neutrophil serine proteases fine-tune the inflammatory response. Int J Biochem Cell Biol (2007) 1.12
Therapeutic effect of anti-TNF-alpha antibodies in an experimental model of anti-neutrophil cytoplasm antibody-associated systemic vasculitis. J Am Soc Nephrol (2005) 1.09
Anticytoplasmic antibodies in Wegener's granulomatosis. Lancet (1985) 1.09
Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor I to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis. Am J Pathol (2004) 1.06
Increased monocyte transcription of the proteinase 3 gene in small vessel vasculitis. Clin Exp Immunol (2005) 1.06
Dipeptidyl peptidase I regulates the development of collagen-induced arthritis. Arthritis Rheum (2005) 1.04
Antineutrophil cytoplasmic antibodies induce human monocytes to produce oxygen radicals in vitro. Arthritis Rheum (2001) 1.00
Dipeptidyl peptidase I-dependent neutrophil recruitment modulates the inflammatory response to Sendai virus infection. J Immunol (2008) 0.92
Upregulation of CD14 and CD18 on monocytes In vitro by antineutrophil cytoplasmic autoantibodies. J Am Soc Nephrol (2000) 0.91
Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells. Exp Cell Res (2010) 0.78
Allelic variation in gene expression is common in the human genome. Genome Res (2003) 5.50
Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection. N Engl J Med (2005) 4.84
Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles. Nat Mater (2008) 4.81
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell (2012) 4.41
The renal arterial resistance index and renal allograft survival. N Engl J Med (2003) 4.36
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med (2009) 4.07
KLF family members regulate intrinsic axon regeneration ability. Science (2009) 3.80
Increased vascular smooth muscle contractility in TRPC6-/- mice. Mol Cell Biol (2005) 3.28
Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage: a multicenter prospective cohort study. J Am Coll Cardiol (2012) 2.97
Urinary neutrophil gelatinase-associated lipocalin distinguishes pre-renal from intrinsic renal failure and predicts outcomes. Kidney Int (2011) 2.94
Activation of the peripheral endocannabinoid system in human obesity. Diabetes (2005) 2.90
Computational analysis and experimental validation of tumor-associated alternative RNA splicing in human cancer. Cancer Res (2003) 2.84
Weight loss and the renin-angiotensin-aldosterone system. Hypertension (2005) 2.58
Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis. J Clin Invest (2002) 2.56
Immunosuppressive treatment protects against angiotensin II-induced renal damage. Am J Pathol (2002) 2.50
Haplotypes and SNPs in 13 lipid-relevant genes explain most of the genetic variance in high-density lipoprotein and low-density lipoprotein cholesterol. Hum Mol Genet (2004) 2.45
Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries. Hypertension (2004) 2.41
Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients. Hypertension (2010) 2.38
Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance. Cell Metab (2013) 2.38
Divalent metal nanoparticles. Science (2007) 2.37
Periadventitial fat releases a vascular relaxing factor. FASEB J (2002) 2.29
Vascular endothelial cell-specific NF-kappaB suppression attenuates hypertension-induced renal damage. Circ Res (2007) 2.25
Genome-wide association study in esophageal cancer using GeneChip mapping 10K array. Cancer Res (2005) 2.22
A new era for cancer treatment: gold-nanoparticle-mediated thermal therapies. Small (2010) 2.21
Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia. Hypertension (2007) 2.17
Retinol-binding protein 4 in human obesity. Diabetes (2006) 2.17
AT1 receptor agonistic antibodies from preeclamptic patients stimulate NADPH oxidase. Circulation (2003) 2.15
Association of specific haplotypes of D2 dopamine receptor gene with vulnerability to heroin dependence in 2 distinct populations. Arch Gen Psychiatry (2004) 2.12
Acquired Brugada syndrome. Am J Cardiol (2003) 2.05
Association between adiponectin and mediators of inflammation in obese women. Diabetes (2003) 2.05
Prorenin receptor is essential for podocyte autophagy and survival. J Am Soc Nephrol (2011) 2.04
Long-term outcomes in acute renal failure patients treated with continuous renal replacement therapies. Am J Kidney Dis (2002) 2.01
Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats. Hypertension (2010) 2.01
The XIST noncoding RNA functions independently of BRCA1 in X inactivation. Cell (2007) 2.00
Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity. Am J Physiol Cell Physiol (2007) 1.99
The sympathetic nervous system in hypertension: assessment by blood pressure variability and ganglionic blockade. J Hypertens (2003) 1.98
Genetic variations at loci involved in the immune response are risk factors for hepatocellular carcinoma. Hepatology (2010) 1.97
Forgetting is regulated through Rac activity in Drosophila. Cell (2010) 1.94
Phosphatidylinositol 3-kinase controls antineutrophil cytoplasmic antibodies-induced respiratory burst in human neutrophils. J Am Soc Nephrol (2002) 1.92
Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. J Clin Invest (2013) 1.92
C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis. J Am Soc Nephrol (2008) 1.92
Regulation of 11beta-HSD genes in human adipose tissue: influence of central obesity and weight loss. Obes Res (2004) 1.91
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization. Cardiovasc Res (2003) 1.89
Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension (2005) 1.89
Resistin gene expression in human adipocytes is not related to insulin resistance. Obes Res (2002) 1.86
Autonomic nervous system and blood pressure regulation in RGS2-deficient mice. Am J Physiol Regul Integr Comp Physiol (2005) 1.84
Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids. J Biol Chem (2010) 1.83
Involvement of functional autoantibodies against vascular receptors in systemic sclerosis. Ann Rheum Dis (2010) 1.83
Nephrogenesis is induced by partial nephrectomy in the elasmobranch Leucoraja erinacea. J Am Soc Nephrol (2003) 1.83
Novel baroreflex activation therapy in resistant hypertension: results of a European multi-center feasibility study. J Am Coll Cardiol (2010) 1.82
Neutrophil-derived cathelicidin promotes adhesion of classical monocytes. Circ Res (2013) 1.80
Pathophysiology of abdominal aortic aneurysms: insights from the elastase-induced model in mice with different genetic backgrounds. Ann N Y Acad Sci (2006) 1.80
Sentinel lymph node biopsy in colon cancer: a prospective multicenter trial. Ann Surg (2007) 1.79
Hormonal regulation of the human adipose-tissue renin-angiotensin system: relationship to obesity and hypertension. J Hypertens (2002) 1.79
Regulatory T cells ameliorate angiotensin II-induced cardiac damage. Circulation (2009) 1.77
Mast cell dipeptidyl peptidase I mediates survival from sepsis. J Clin Invest (2004) 1.75
Agonistic autoantibodies to the AT1 receptor in a transgenic rat model of preeclampsia. Hypertension (2005) 1.74
Plasma exchange for primary autoimmune autonomic failure. N Engl J Med (2005) 1.71
Allele-specific chromatin immunoprecipitation studies show genetic influence on chromatin state in human genome. PLoS Genet (2007) 1.71
Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes (2002) 1.70
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex. Development (2010) 1.68
Identification of hypertension-related genes through an integrated genomic-transcriptomic approach. Circ Res (2005) 1.67
The BK channel beta1 subunit gene is associated with human baroreflex and blood pressure regulation. J Hypertens (2002) 1.65
Pseudo-pseudo Meigs' syndrome. Lancet (2005) 1.63
Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose. J Biol Chem (2008) 1.62
Donor-specific anti-HLA Abs and graft failure in matched unrelated donor hematopoietic stem cell transplantation. Blood (2011) 1.61
PTK7 as a novel marker for favorable gastric cancer patient survival. J Surg Oncol (2012) 1.60
Decreased catecholamine degradation associates with shock and kidney injury after cardiac surgery. J Am Soc Nephrol (2009) 1.60
Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo. Circulation (2005) 1.59
Influence of sibutramine treatment on sympathetic vasomotor tone in obese subjects. Clin Pharmacol Ther (2006) 1.59
Mechanisms of ADRF release from rat aortic adventitial adipose tissue. Am J Physiol Heart Circ Physiol (2003) 1.57
Plasmonic nanobubbles as transient vapor nanobubbles generated around plasmonic nanoparticles. ACS Nano (2010) 1.57
Agonistic angiotensin II type 1 receptor autoantibodies in postpartum women with a history of preeclampsia. Hypertension (2007) 1.56
ERG oncogene modulates prostaglandin signaling in prostate cancer cells. Cancer Biol Ther (2011) 1.56
The seroprevalence of pandemic influenza H1N1 (2009) virus in China. PLoS One (2011) 1.54
Adiponectin is a novel humoral vasodilator. Cardiovasc Res (2007) 1.52
Mutation in the ARH gene and a chromosome 13q locus influence cholesterol levels in a new form of digenic-recessive familial hypercholesterolemia. Circ Res (2002) 1.52
Chronic cyclooxygenase-2 inhibition does not alter blood pressure and kidney function in renovascular hypertensive rats. J Hypertens (2004) 1.51
Bone marrow edema syndrome of the femoral head: treatment with the prostacyclin analogue iloprost vs. core decompression: an MRI-controlled study. Wien Klin Wochenschr (2005) 1.51
23Na magnetic resonance imaging-determined tissue sodium in healthy subjects and hypertensive patients. Hypertension (2013) 1.51
Insulin resistance in healthy prepubertal twins. J Pediatr (2004) 1.49
Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation. Biochem J (2007) 1.49
Agonistic antibodies directed at the angiotensin II, AT1 receptor in preeclampsia. J Soc Gynecol Investig (2006) 1.49
An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction. Am J Hum Genet (2007) 1.48
Hypertension, sodium retention, calcium excretion and osteopenia in Dahl rats. J Hypertens (2004) 1.48
TNF-alpha--accelerated apoptosis abrogates ANCA-mediated neutrophil respiratory burst by a caspase-dependent mechanism. Kidney Int (2002) 1.48
Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. Hypertension (2008) 1.48
Efficacy of different technical procedures for sentinel lymph node biopsy in gastric cancer staging. Ann Surg Oncol (2007) 1.46
Response to preoperative short-course radiotherapy in locally advanced rectal cancer: value of f-fluorodeoxyglucose positron emission tomography. Onkologie (2008) 1.46
Proteomic identification of FHL1 as the protein mutated in human reducing body myopathy. J Clin Invest (2008) 1.46