Published in Int J Epidemiol on January 23, 2012
A data-driven approach to preprocessing Illumina 450K methylation array data. BMC Genomics (2013) 3.59
Factors underlying variable DNA methylation in a human community cohort. Proc Natl Acad Sci U S A (2012) 3.20
Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array. Epigenetics Chromatin (2013) 2.93
Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet (2014) 2.58
Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease. Mod Pathol (2013) 1.95
From promises to practical strategies in epigenetic epidemiology. Nat Rev Genet (2013) 1.82
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array. Epigenetics Chromatin (2013) 1.62
Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits. Mol Psychiatry (2013) 1.60
Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs. Aging Cell (2012) 1.55
Breastfeeding effects on DNA methylation in the offspring: A systematic literature review. PLoS One (2017) 1.38
Transgenerational epigenetic inheritance: how important is it? Nat Rev Genet (2013) 1.32
Prenatal famine and genetic variation are independently and additively associated with DNA methylation at regulatory loci within IGF2/H19. PLoS One (2012) 1.24
The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years. Clin Epigenetics (2013) 1.22
The future of genomics for developmentalists. Dev Psychopathol (2013) 1.21
Is epidemiology ready for epigenetics? Int J Epidemiol (2012) 1.17
Childhood exposure to violence and lifelong health: clinical intervention science and stress-biology research join forces. Dev Psychopathol (2013) 1.14
Achievements and challenges in the biology of environmental effects. Proc Natl Acad Sci U S A (2012) 1.12
Epigenetic regulation of the oxytocin receptor gene: implications for behavioral neuroscience. Front Neurosci (2013) 1.08
Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies. Epigenetics (2013) 1.08
DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain. Am J Med Genet B Neuropsychiatr Genet (2014) 1.07
Genome-wide methylomic analysis of monozygotic twins discordant for adolescent depression. Biol Psychiatry (2014) 1.07
Epigenetic epidemiology: promises for public health research. Environ Mol Mutagen (2014) 1.06
Epigenome-wide Association Studies and the Interpretation of Disease -Omics. PLoS Genet (2016) 1.05
Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences. BMC Med (2012) 1.04
Concordant and discordant DNA methylation signatures of aging in human blood and brain. Epigenetics Chromatin (2015) 1.01
The role of longitudinal cohort studies in epigenetic epidemiology: challenges and opportunities. Genome Biol (2012) 1.00
The Role of Epigenetic Change in Autism Spectrum Disorders. Front Neurol (2015) 0.95
Erythrocyte folate concentrations, CpG methylation at genomically imprinted domains, and birth weight in a multiethnic newborn cohort. Epigenetics (2014) 0.93
DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants. J Eur Acad Dermatol Venereol (2012) 0.93
Methylomic analysis of salivary DNA in childhood ADHD identifies altered DNA methylation in VIPR2. J Child Psychol Psychiatry (2015) 0.91
Discordance of DNA methylation variance between two accessible human tissues. Sci Rep (2015) 0.91
Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status. J Epidemiol Community Health (2015) 0.90
Epigenetic studies in Alzheimer's disease: current findings, caveats, and considerations for future studies. Am J Med Genet B Neuropsychiatr Genet (2013) 0.90
Association of maternal and nutrient supply line factors with DNA methylation at the imprinted IGF2/H19 locus in multiple tissues of newborn twins. Epigenetics (2013) 0.89
Epigenetic studies of schizophrenia: progress, predicaments, and promises for the future. Schizophr Bull (2012) 0.89
Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome. Int J Epidemiol (2015) 0.86
Epigenetics of progression of chronic kidney disease: fact or fantasy? Semin Nephrol (2013) 0.86
Physical activity and differential methylation of breast cancer genes assayed from saliva: a preliminary investigation. Ann Behav Med (2013) 0.85
Differential methylation of the oxytocin receptor gene in patients with anorexia nervosa: a pilot study. PLoS One (2014) 0.84
The promise and challenges of blood spot methylomics. Epigenetics (2013) 0.84
The Influences of Genetic and Environmental Factors on Methylome-wide Association Studies for Human Diseases. Curr Genet Med Rep (2014) 0.82
The role of epigenetic mechanisms and processes in autoimmune disorders. Biologics (2012) 0.82
Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model. Mech Ageing Dev (2016) 0.80
Improved reporting of DNA methylation data derived from studies of the human placenta. Epigenetics (2014) 0.79
Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions. Hum Mol Genet (2016) 0.78
Oral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylation. Clin Epigenetics (2014) 0.78
Establishing an analytic pipeline for genome-wide DNA methylation. Clin Epigenetics (2016) 0.77
Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum. Adv Exp Med Biol (2016) 0.77
Transcriptional implications of intragenic DNA methylation in the oestrogen receptor alpha gene in breast cancer cells and tissues. BMC Cancer (2015) 0.77
DNA methylation and substance-use risk: a prospective, genome-wide study spanning gestation to adolescence. Transl Psychiatry (2016) 0.76
How to make DNA methylome wide association studies more powerful. Epigenomics (2016) 0.76
Reliability of DNA methylation measures from dried blood spots and mononuclear cells using the HumanMethylation450k BeadArray. Sci Rep (2016) 0.76
Epigenetics of Osteoporosis: Critical Analysis of Epigenetic Epidemiology Studies. Curr Genomics (2015) 0.76
Putting the 'epi' into epigenetics research in psychiatry. J Epidemiol Community Health (2013) 0.76
Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide. Transl Psychiatry (2017) 0.75
Epigenetic evidence for involvement of the oxytocin receptor gene in obsessive-compulsive disorder. BMC Neurosci (2016) 0.75
Accounting for Life-Course Exposures in Epigenetic Biomarker Association Studies: Early Life Socioeconomic Position, Candidate Gene DNA Methylation, and Adult Cardiometabolic Risk. Am J Epidemiol (2016) 0.75
Techniques and Approaches to Genetic Analyses in Nephrological Disorders. J Pediatr Genet (2015) 0.75
Gene, Environment and Methylation (GEM): a tool suite to efficiently navigate large scale epigenome wide association studies and integrate genotype and interaction between genotype and environment. BMC Bioinformatics (2016) 0.75
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet (2009) 18.90
The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol (2010) 13.99
A global test for groups of genes: testing association with a clinical outcome. Bioinformatics (2004) 10.82
Principles and challenges of genomewide DNA methylation analysis. Nat Rev Genet (2010) 10.71
Analyzing gene expression data in terms of gene sets: methodological issues. Bioinformatics (2007) 9.87
Epigenome-wide association studies for common human diseases. Nat Rev Genet (2011) 7.96
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics (2011) 7.38
Parental origin of sequence variants associated with complex diseases. Nature (2009) 7.21
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol (2010) 7.00
Quantitative comparison of genome-wide DNA methylation mapping technologies. Nat Biotechnol (2010) 5.96
Tobacco-smoking-related differential DNA methylation: 27K discovery and replication. Am J Hum Genet (2011) 5.18
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific. Hum Mol Genet (2009) 4.25
Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome. Genome Res (2010) 3.17
Allelic skewing of DNA methylation is widespread across the genome. Am J Hum Genet (2010) 3.17
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum Mol Genet (2011) 2.99
Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. FASEB J (2010) 2.74
Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics (2006) 2.68
Associations with early-life socio-economic position in adult DNA methylation. Int J Epidemiol (2011) 2.67
Cell type-specific DNA methylation at intragenic CpG islands in the immune system. Genome Res (2011) 2.51
Moving AHEAD with an international human epigenome project. Nature (2008) 2.38
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet (2010) 2.33
Epigenetic epidemiology of common complex disease: prospects for prediction, prevention, and treatment. PLoS Med (2010) 2.20
A longitudinal study of epigenetic variation in twins. Epigenetics (2010) 2.06
Aging and chronic sun exposure cause distinct epigenetic changes in human skin. PLoS Genet (2010) 2.03
Tissue-specific dysregulation of DNA methylation in aging. Aging Cell (2010) 1.90
The epigenome: archive of the prenatal environment. Epigenetics (2009) 1.82
Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans. Epigenetics (2011) 1.55
The thrifty epigenotype: an acquired and heritable predisposition for obesity and diabetes? Bioessays (2008) 1.47
Allele-specific methylation in the human genome: implications for genetic studies of complex disease. Epigenetics (2010) 1.37
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science (2003) 28.61
Role of genotype in the cycle of violence in maltreated children. Science (2002) 13.50
Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature (2011) 10.16
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet (2012) 4.05
A data-driven approach to preprocessing Illumina 450K methylation array data. BMC Genomics (2013) 3.59
Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biol (2012) 3.31
Allelic skewing of DNA methylation is widespread across the genome. Am J Hum Genet (2010) 3.17
Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum Mol Genet (2011) 2.99
A longitudinal study of epigenetic variation in twins. Epigenetics (2010) 2.06
Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus. PLoS One (2010) 1.93
Protection from genetic diathesis in attention-deficit/hyperactivity disorder: possible complementary roles of exercise. J Am Acad Child Adolesc Psychiatry (2013) 1.54
Epigenetic mediation of environmental influences in major psychotic disorders. Schizophr Bull (2009) 1.47
Allele-specific methylation in the human genome: implications for genetic studies of complex disease. Epigenetics (2010) 1.37
Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. Genome Biol (2014) 1.37
Differential epigenomic and transcriptomic responses in subcutaneous adipose tissue between low and high responders to caloric restriction. Am J Clin Nutr (2009) 1.30
Bisulfite-based epityping on pooled genomic DNA provides an accurate estimate of average group DNA methylation. Epigenetics Chromatin (2009) 1.29
Epigenetic studies of psychosis: current findings, methodological approaches, and implications for postmortem research. Biol Psychiatry (2010) 1.24
The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression. BMC Med Genet (2006) 1.24
Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model. PLoS One (2009) 1.19
Trajectories leading to autism spectrum disorders are affected by paternal age: findings from two nationally representative twin studies. J Child Psychol Psychiatry (2010) 1.14
Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes. Am J Hum Genet (2004) 1.12
Drugs and addiction: an introduction to epigenetics. Addiction (2011) 1.12
Functional effects of a tandem duplication polymorphism in the 5'flanking region of the DRD4 gene. Biol Psychiatry (2004) 1.10
Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities. Int J Neuropsychopharmacol (2013) 1.09
Application of microarrays to the analysis of the inactivation status of human X-linked genes expressed in lymphocytes. Eur J Hum Genet (2004) 1.07
Sleep quality and diurnal preference in a sample of young adults: associations with 5HTTLPR, PER3, and CLOCK 3111. Am J Med Genet B Neuropsychiatr Genet (2011) 1.06
Stochastic choice of allelic expression in human neural stem cells. Stem Cells (2012) 1.06
DNA pooling analysis of 21 norepinephrine transporter gene SNPs with attention deficit hyperactivity disorder: no evidence for association. Am J Med Genet B Neuropsychiatr Genet (2005) 1.04
Current status and future prospects for epigenetic psychopharmacology. Epigenetics (2012) 0.96
Family-based association study between brain-derived neurotrophic factor gene polymorphisms and attention deficit hyperactivity disorder in UK and Taiwanese samples. Am J Med Genet B Neuropsychiatr Genet (2007) 0.94
Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition. Brain (2011) 0.93
DNA methylation profiling using bisulfite-based epityping of pooled genomic DNA. Methods (2010) 0.93
A longitudinal twin study of skewed X chromosome-inactivation. PLoS One (2011) 0.93
Eating disorders, gene-environment interactions and epigenetics. Neurosci Biobehav Rev (2010) 0.92
Epigenetics, genomic mutations and cognitive function. Cogn Neuropsychiatry (2009) 0.92
Decreased methylation of the NK3 receptor coding gene (TACR3) after cocaine-induced place preference in marmoset monkeys. Addict Biol (2011) 0.91
SORL1 and SIRT1 mRNA expression and promoter methylation levels in aging and Alzheimer's Disease. Neurochem Int (2012) 0.90
Epigenetic studies in Alzheimer's disease: current findings, caveats, and considerations for future studies. Am J Med Genet B Neuropsychiatr Genet (2013) 0.90
Epigenetic studies of schizophrenia: progress, predicaments, and promises for the future. Schizophr Bull (2012) 0.89
Hypermethylation in the ZBTB20 gene is associated with major depressive disorder. Genome Biol (2014) 0.88
The XVth World Congress of Psychiatric Genetics, October 7-11, 2007: Rapporteur summaries of oral presentations. Am J Med Genet B Neuropsychiatr Genet (2008) 0.88
Epigenetic and genetic variation at the IGF2/H19 imprinting control region on 11p15.5 is associated with cerebellum weight. Epigenetics (2012) 0.84
A genetic association study of DNA methylation levels in the DRD4 gene region finds associations with nearby SNPs. Behav Brain Funct (2012) 0.83
Anxiety sensitivity in adolescence and young adulthood: the role of stressful life events, 5HTTLPR and their interaction. Depress Anxiety (2012) 0.83
The mitochondrial epigenome: a role in Alzheimer's disease? Epigenomics (2014) 0.83
Association study of promoter polymorphisms at the dopamine transporter gene in Attention Deficit Hyperactivity Disorder. BMC Psychiatry (2009) 0.82
Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease. Mol Neurodegener (2014) 0.82
Family-based association study of serotonin transporter gene polymorphisms in attention deficit hyperactivity disorder: no evidence for association in UK and Taiwanese samples. Am J Med Genet B Neuropsychiatr Genet (2005) 0.81
Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients. J Alzheimers Dis (2014) 0.81
CNP and DPYSL2 mRNA expression and promoter methylation levels in brain of Alzheimer's disease patients. J Alzheimers Dis (2013) 0.79
DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice. Mol Brain (2012) 0.77
Quantitative promoter DNA methylation analysis of four candidate genes in anorexia nervosa: a pilot study. J Psychiatr Res (2012) 0.76
Rapid Down-Regulation of Glucocorticoid Receptor Gene Expression in the Dentate Gyrus after Acute Stress in vivo: Role of DNA Methylation and MicroRNA Activity. Neuroendocrinology (2016) 0.76
Research Highlights: epigenetic changes to serotonin receptor gene expression in schizophrenia and bipolar disorder. Epigenomics (2011) 0.75
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS. Sci Transl Med (2022) 0.75