Published in Genet Res on August 01, 1990
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The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes Dev (1998) 4.11
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Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell (1984) 3.56
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Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene. Cell (1991) 3.31
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Replacement of diseased mouse liver by hepatic cell transplantation. Science (1994) 3.18
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Transplantation of testis germinal cells into mouse seminiferous tubules. Int J Dev Biol (1997) 3.10
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Specific expression of an elastase-human growth hormone fusion gene in pancreatic acinar cells of transgenic mice. Nature (1985) 2.77
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Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice. Cell (1984) 2.59
Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development. Science (2001) 2.59
Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene. Development (1998) 2.49
The role of Rab3A in neurotransmitter release. Nature (1994) 2.48
A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. Science (1985) 2.47
Genetically haploid spermatids are phenotypically diploid. Nature (1989) 2.45
Transplantation of male germ line stem cells restores fertility in infertile mice. Nat Med (2000) 2.37
The dopamine beta-hydroxylase gene promoter directs expression of E. coli lacZ to sympathetic and other neurons in adult transgenic mice. Neuron (1991) 2.37
Spermatid-specific expression of protamine 1 in transgenic mice. Proc Natl Acad Sci U S A (1987) 2.36
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell (1988) 2.36
Pancreatic neoplasia induced by SV40 T-antigen expression in acinar cells of transgenic mice. Science (1987) 2.35
Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc Natl Acad Sci U S A (1994) 2.34
Pancreatic neoplasia induced by ras expression in acinar cells of transgenic mice. Cell (1987) 2.32
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Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells. Proc Natl Acad Sci U S A (2000) 2.30
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Production of transgenic rabbits, sheep and pigs by microinjection. Nature (1985) 2.26
High-level erythroid expression of human alpha-globin genes in transgenic mice. Proc Natl Acad Sci U S A (1989) 2.26
Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. Proc Natl Acad Sci U S A (1987) 2.24
Short-term synaptic plasticity is altered in mice lacking synapsin I. Cell (1993) 2.23
Pattern and kinetics of mouse donor spermatogonial stem cell colonization in recipient testes. Biol Reprod (1999) 2.21
Abnormal sexual development in transgenic mice chronically expressing müllerian inhibiting substance. Nature (1990) 2.20
Oncogene-induced liver neoplasia in transgenic mice. Oncogene (1989) 2.20
Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice. Proc Natl Acad Sci U S A (2001) 2.14
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SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice. Nature (1985) 2.10
Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice. Proc Natl Acad Sci U S A (1991) 2.06
A novel MHC class II epitope expressed in thymic medulla but not cortex. Nature (1989) 2.06
Protamine 3'-untranslated sequences regulate temporal translational control and subcellular localization of growth hormone in spermatids of transgenic mice. Genes Dev (1989) 2.06
Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice. J Clin Invest (1998) 2.04
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RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors. EMBO J (1996) 2.02
Reconstitution of spermatogenesis from frozen spermatogonial stem cells. Nat Med (1996) 2.00
Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice. Nature (1984) 2.00