Published in Am J Hum Biol on January 30, 2012
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Caloric restriction delays disease onset and mortality in rhesus monkeys. Science (2009) 9.84
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Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis. Proc Natl Acad Sci U S A (2009) 2.33
Attenuation of sarcopenia by dietary restriction in rhesus monkeys. J Gerontol A Biol Sci Med Sci (2008) 2.00
Transcriptional profiles associated with aging and middle age-onset caloric restriction in mouse hearts. Proc Natl Acad Sci U S A (2002) 1.97
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Caloric restriction suppresses apoptotic cell death in the mammalian cochlea and leads to prevention of presbycusis. Neurobiol Aging (2006) 1.37
Energy restriction lowers the expression of genes linked to inflammation, the cytoskeleton, the extracellular matrix, and angiogenesis in mouse adipose tissue. J Nutr (2006) 1.36
A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging. Biochem J (2005) 1.35
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Long-term calorie restriction reduces proton leak and hydrogen peroxide production in liver mitochondria. Am J Physiol Endocrinol Metab (2004) 1.32
Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate. Cancer Res (2008) 1.30
Effects of short- and medium-term calorie restriction on muscle mitochondrial proton leak and reactive oxygen species production. Am J Physiol Endocrinol Metab (2004) 1.30
Molecular analyses of mtDNA deletion mutations in microdissected skeletal muscle fibers from aged rhesus monkeys. Aging Cell (2004) 1.27
Metabolic shifts due to long-term caloric restriction revealed in nonhuman primates. Exp Gerontol (2009) 1.26
Intentional weight loss reduces mortality rate in a rodent model of dietary obesity. Obes Res (2005) 1.24
Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss. Hear Res (2006) 1.21
The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase gamma. Neurobiol Aging (2007) 1.19
Age-related impairment of the transcriptional responses to oxidative stress in the mouse heart. Physiol Genomics (2003) 1.19
A design and statistical perspective on microarray gene expression studies in nutrition: the need for playful creativity and scientific hard-mindedness. Nutrition (2003) 1.13
The impact of alpha-lipoic acid, coenzyme Q10 and caloric restriction on life span and gene expression patterns in mice. Free Radic Biol Med (2004) 1.12
Insulin resistance and impaired insulin secretion in prenatally androgenized male rhesus monkeys. J Clin Endocrinol Metab (2004) 1.09
Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle. Exp Gerontol (2010) 1.08
Krebs cycle enzymes from livers of old mice are differentially regulated by caloric restriction. Exp Gerontol (2004) 1.08
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Influence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice. Exp Gerontol (2003) 1.03
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Longitudinal analysis of early stage sarcopenia in aging rhesus monkeys. Exp Gerontol (2008) 0.95
Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. J Gerontol A Biol Sci Med Sci (2012) 0.92
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Auditory function in rhesus monkeys: effects of aging and caloric restriction in the Wisconsin monkeys five years later. Hear Res (2010) 0.91
Impairment of the transcriptional responses to oxidative stress in the heart of aged C57BL/6 mice. Ann N Y Acad Sci (2004) 0.91
A methyl-deficient diet modifies histone methylation and alters Igf2 and H19 repression in the prostate. Prostate (2008) 0.90
A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys. Aging Cell (2013) 0.89
Enzymes of glycerol and glyceraldehyde metabolism in mouse liver: effects of caloric restriction and age on activities. Biosci Rep (2008) 0.87
Effects of caloric restriction on age-related hearing loss in rodents and rhesus monkeys. Curr Aging Sci (2010) 0.86
Assessment of nutritional status in rhesus monkeys: comparison of dual-energy X-ray absorptiometry and stable isotope dilution. J Med Primatol (2005) 0.86
Long-term calorie restriction decreases metabolic cost of movement and prevents decrease of physical activity during aging in rhesus monkeys. Exp Gerontol (2013) 0.86
Gene expression profiling reveals differential effects of sodium selenite, selenomethionine, and yeast-derived selenium in the mouse. Genes Nutr (2011) 0.86
Calorie restriction: progress during mid-2005-mid-2006. Exp Gerontol (2006) 0.85
Gene expression profile of the aging brain. Arch Neurol (2002) 0.84
Serine utilization in mouse liver: influence of caloric restriction and aging. FEBS Lett (2005) 0.82
Fructose metabolizing enzymes from mouse liver: influence of age and caloric restriction. Biochim Biophys Acta (2004) 0.81
Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys. Exp Gerontol (2011) 0.81
Metabolizable energy intake during long-term calorie restriction in rhesus monkeys. Exp Gerontol (2007) 0.81
alpha- and gamma-Tocopherol prevent age-related transcriptional alterations in the heart and brain of mice. J Nutr (2008) 0.80
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Tympanometry in rhesus monkeys: effects of aging and caloric restriction. Int J Audiol (2008) 0.78
Egr-1 and Hipk2 are required for the TrkA to p75(NTR) switch that occurs downstream of IGF1-R. Neurobiol Aging (2008) 0.78
Skeletal effects of long-term caloric restriction in rhesus monkeys. Age (Dordr) (2011) 0.76
Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver. Biogerontology (2008) 0.75