Published in J Amino Acids on December 22, 2010
Structural basis for a bispecific NADP+ and CoA binding site in an archaeal malonyl-coenzyme A reductase. J Biol Chem (2013) 0.81
Elaboration of a fragment library hit produces potent and selective aspartate semialdehyde dehydrogenase inhibitors. Bioorg Med Chem (2015) 0.79
Construction of a synthetic metabolic pathway for biosynthesis of the non-natural methionine precursor 2,4-dihydroxybutyric acid. Nat Commun (2017) 0.79
Structural Insights into the Tetrameric State of Aspartate-β-semialdehyde Dehydrogenases from Fungal Species. Sci Rep (2016) 0.78
Systematic Analysis of Intracellular-targeting Antimicrobial Peptides, Bactenecin 7, Hybrid of Pleurocidin and Dermaseptin, Proline-Arginine-rich Peptide, and Lactoferricin B, by Using Escherichia coli Proteome Microarrays. Mol Cell Proteomics (2016) 0.77
Structure of homoserine O-acetyltransferase from Staphylococcus aureus: the first Gram-positive ortholog structure. Acta Crystallogr F Struct Biol Commun (2014) 0.77
Identification of potential leads against 4-hydroxytetrahydrodipicolinate synthase from Mycobacterium tuberculosis. Bioinformation (2016) 0.75
Structural identification of a bacterial quorum-sensing signal containing boron. Nature (2002) 8.11
Worldwide emergence of extensively drug-resistant tuberculosis. Emerg Infect Dis (2007) 6.41
Comparison of super-secondary structures in proteins. J Mol Biol (1973) 4.85
Community-associated methicillin-resistant Staphylococcus aureus isolates causing healthcare-associated infections. Emerg Infect Dis (2007) 3.12
Cloning and characterization of the asd gene of Salmonella typhimurium: use in stable maintenance of recombinant plasmids in Salmonella vaccine strains. Gene (1990) 2.80
Recent advances in the formation of the bacterial peptidoglycan monomer unit. Nat Prod Rep (2001) 2.51
Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria. Peptides (2004) 2.05
Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii. J Bacteriol (2008) 2.02
Structure of holo-glyceraldehyde-3-phosphate dehydrogenase from Bacillus stearothermophilus at 1.8 A resolution. J Mol Biol (1987) 1.90
The activity reaction core and plasticity of metabolic networks. PLoS Comput Biol (2005) 1.66
Identification of a new gene essential for germination of Bacillus subtilis spores with Ca2+-dipicolinate. J Bacteriol (2003) 1.55
The central enzymes of the aspartate family of amino acid biosynthesis. Acc Chem Res (2001) 1.41
The role of sulfhydryl groups in the activity of D-glyceraldehyde 3-phosphate dehydrogenase. J Biol Chem (1953) 1.38
Bacterial amino acid transport proteins: occurrence, functions, and significance for biotechnological applications. Appl Microbiol Biotechnol (2001) 1.22
Crystal structure of Mycobacterium tuberculosis diaminopimelate decarboxylase, an essential enzyme in bacterial lysine biosynthesis. J Biol Chem (2003) 1.15
Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis. J Mol Biol (1999) 1.10
Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J Biol Chem (2006) 1.03
A structural basis for the mechanism of aspartate-beta-semialdehyde dehydrogenase from Vibrio cholerae. Protein Sci (2003) 1.02
Capture of an intermediate in the catalytic cycle of L-aspartate-beta-semialdehyde dehydrogenase. Proc Natl Acad Sci U S A (2003) 1.01
A new branch in the family: structure of aspartate-beta-semialdehyde dehydrogenase from Methanococcus jannaschii. J Mol Biol (2005) 1.01
Active site analysis of the potential antimicrobial target aspartate semialdehyde dehydrogenase. Biochemistry (2001) 0.99
Use of structural comparisons to select mutagenic targets in aspartate-beta-semialdehyde dehydrogenase. Biochemistry (1995) 0.94
Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog. Acta Crystallogr D Biol Crystallogr (2010) 0.93
Identification of an essential cysteine in the reaction catalyzed by aspartate-beta-semialdehyde dehydrogenase from Escherichia coli. Biochim Biophys Acta (1992) 0.92
Identification of selective enzyme inhibitors by fragment library screening. J Biomol Screen (2010) 0.89
Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr D Biol Crystallogr (2004) 0.88
Oxyanion Specificity of Aspartate-beta-semialdehyde Dehydrogenase. Inorg Chem (1999) 0.87
The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae. Acta Crystallogr D Biol Crystallogr (2008) 0.85
The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr D Biol Crystallogr (2004) 0.83
Critical catalytic functional groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr D Biol Crystallogr (2004) 0.83
Aspartate-beta-semialdehyde dehydrogenase from Escherichia coli. Affinity labeling with the substrate analogue L-2-amino-4-oxo-5-chloropentanoic acid: an example of half-site reactivity. Eur J Biochem (1980) 0.82
Affinity labeling of the Escherichia coli aspartate-beta-semialdehyde dehydrogenase with an alkylating coenzyme analogue. Half-site reactivity and competition with the substrate alkylating analogue. Eur J Biochem (1980) 0.81
Ultrasensitive detection of scrapie prion protein using seeded conversion of recombinant prion protein. Nat Methods (2007) 3.74
Simplified ultrasensitive prion detection by recombinant PrP conversion with shaking. Nat Methods (2008) 2.56
Immunohistochemical localization of aspartoacylase in the rat central nervous system. J Comp Neurol (2004) 1.47
Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects. J Biol Chem (2007) 1.37
Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death. Immunity (2013) 1.07
Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J Biol Chem (2006) 1.03
A structural basis for the mechanism of aspartate-beta-semialdehyde dehydrogenase from Vibrio cholerae. Protein Sci (2003) 1.02
Capture of an intermediate in the catalytic cycle of L-aspartate-beta-semialdehyde dehydrogenase. Proc Natl Acad Sci U S A (2003) 1.01
Isolation of novel synthetic prion strains by amplification in transgenic mice coexpressing wild-type and anchorless prion proteins. J Virol (2012) 1.01
The initial step in the archaeal aspartate biosynthetic pathway catalyzed by a monofunctional aspartokinase. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.99
Purification and preliminary characterization of brain aspartoacylase. Arch Biochem Biophys (2003) 0.98
Conformational change in rhomboid protease GlpG induced by inhibitor binding to its S' subsites. Biochemistry (2012) 0.96
Role of cyclophilin A from brains of prion-infected mice in stimulation of cytokine release by microglia and astroglia in vitro. J Biol Chem (2011) 0.95
Hemin interactions and alterations of the subcellular localization of prion protein. J Biol Chem (2007) 0.94
Expansion of the aspartate beta-semialdehyde dehydrogenase family: the first structure of a fungal ortholog. Acta Crystallogr D Biol Crystallogr (2010) 0.93
Recombinant prion protein refolded with lipid and RNA has the biochemical hallmarks of a prion but lacks in vivo infectivity. PLoS One (2013) 0.90
Structural characterization of the E2 domain of APL-1, a Caenorhabditis elegans homolog of human amyloid precursor protein, and its heparin binding site. J Biol Chem (2009) 0.90
The E2 domains of APP and APLP1 share a conserved mode of dimerization. Biochemistry (2011) 0.89
Identification of selective enzyme inhibitors by fragment library screening. J Biomol Screen (2010) 0.89
Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg Med Chem Lett (2009) 0.89
Structural characterization of inhibitors with selectivity against members of a homologous enzyme family. Chem Biol Drug Des (2011) 0.88
Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr D Biol Crystallogr (2004) 0.88
The structural basis for allosteric inhibition of a threonine-sensitive aspartokinase. J Biol Chem (2008) 0.87
A rapid method for the purification of methanol dehydrogenase from Methylobacterium extorquens. Protein Expr Purif (2005) 0.86
4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase. J Med Chem (2007) 0.86
Human polyomavirus JC small regulatory agnoprotein forms highly stable dimers and oligomers: implications for their roles in agnoprotein function. Virology (2011) 0.85
The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae. Acta Crystallogr D Biol Crystallogr (2008) 0.85
Critical catalytic functional groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr D Biol Crystallogr (2004) 0.83
The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase. Acta Crystallogr D Biol Crystallogr (2004) 0.83
Dissociation of recombinant prion protein fibrils into short protofilaments: implications for the endocytic pathway and involvement of the N-terminal domain. Biochemistry (2012) 0.81
Aspartoacylase catalytic deficiency as the cause of Canavan disease: a structural perspective. Biochemistry (2014) 0.80
Combination of amino acid/dipeptide with nitric oxide donating oleanolic acid derivatives as PepT1 targeting antitumor prodrugs. J Med Chem (2014) 0.79
Identification of prion inhibitors by a fluorescence-polarization-based competitive binding assay. Anal Biochem (2006) 0.78
Synthesis and evaluation of alternative substrates for arginase. Bioorg Chem (2002) 0.77
Correction: The Distribution of Prion Protein Allotypes Differs Between Sporadic and Iatrogenic Creutzfeldt-Jakob Disease Patients. PLoS Pathog (2016) 0.75
Professionalism considerations. Anesthesiology (2009) 0.75
Nonsolvent-assisted fabrication of multi-scaled polylactide as superhydrophobic surfaces. Soft Matter (2016) 0.75
[Clinical performance of antigen-specific interferon-gamma assay for the diagnosis of latent tuberculosis in risky hospital-based populations]. Med Clin (Barc) (2008) 0.75
Electric-field response of discotic hexabenzocoronene (HBC) liquid crystals. Molecules (2011) 0.75