Published in PLoS One on February 21, 2012
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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell (2005) 10.61
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YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol (2007) 8.11
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell (2009) 7.39
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis (2006) 6.64
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TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat Cell Biol (2008) 3.44
The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes Dev (2010) 3.37
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. J Biol Chem (2009) 3.20
YAP regulates neural progenitor cell number via the TEA domain transcription factor. Genes Dev (2008) 3.16
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Expansion of hematopoietic stem cells in the developing liver of a mouse embryo. Blood (2000) 1.93
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Structural features and ligand binding properties of tandem WW domains from YAP and TAZ, nuclear effectors of the Hippo pathway. Biochemistry (2011) 1.10
FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools. Development (2011) 1.03
Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture. Cell Stem Cell (2008) 0.97
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Orientation-selective adaptation to illusory contours in human visual cortex. J Neurosci (2007) 1.67
Feature-based attention modulates orientation-selective responses in human visual cortex. Neuron (2007) 1.64
Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4. Mol Cell Biol (2003) 1.50
Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion. Dev Biol (2006) 1.50
Signaling via the Tgf-beta type I receptor Alk5 in heart development. Dev Biol (2008) 1.42
Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia. Development (2004) 1.40
Intact signaling by transforming growth factor beta is not required for termination of liver regeneration in mice. Hepatology (2004) 1.33
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia. Blood (2011) 1.28
Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects. BMC Dev Biol (2006) 1.20
Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn (2004) 1.08
Smad7 promotes self-renewal of hematopoietic stem cells. Blood (2006) 1.03
HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development. Blood (2007) 1.02
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Transient disruption of autocrine TGF-beta signaling leads to enhanced survival and proliferation potential in single primitive human hemopoietic progenitor cells. J Immunol (2002) 0.96
TGF-beta type II receptor-deficient thymocytes develop normally but demonstrate increased CD8+ proliferation in vivo. Blood (2005) 0.94
Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling. Physiol Genomics (2005) 0.90
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands. Arthritis Rheum (2007) 0.90
Design and implementation of a point-of-care computerized system for drug therapy in Stockholm metropolitan health region--Bridging the gap between knowledge and practice. Int J Med Inform (2006) 0.90
RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion. Blood (2012) 0.88
Expression of integrin α2 receptor in human cord blood CD34+CD38-CD90+ stem cells engrafting long-term in NOD/SCID-IL2Rγ(c) null mice. Stem Cells (2013) 0.87
Forward RNAi screens in primary human hematopoietic stem/progenitor cells. Blood (2009) 0.87
Neuron-specific TGF-beta signaling deficiency results in retinal detachment and cataracts in mice. Biochem Biophys Res Commun (2006) 0.85
Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5. Dev Biol (2005) 0.84
Identification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem and progenitor cells. Blood (2013) 0.83
Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation. Lab Invest (2009) 0.83
FACS binding assay for analysing GDNF interactions. J Neurosci Methods (2013) 0.78
W41/W41 blastocyst complementation: a system for genetic modeling of hematopoiesis. Blood (2009) 0.78
Problem severity profiles of substance abusing women in European Therapeutic Communities: influence of psychiatric problems. J Subst Abuse Treat (2004) 0.77
Anterior dynamic ultrasound of the infant hip: evaluation of investigator dependence. Acta Radiol (2009) 0.77
RNA interference screening to detect targetable molecules in hematopoietic stem cells. Curr Opin Hematol (2014) 0.77
Implicit representations of luminance and the temporal structure of moving stimuli in multiple regions of human visual cortex revealed by multivariate pattern classification analysis. J Neurophysiol (2013) 0.76
The effect of contrast on perceived speed and flicker. J Vis (2012) 0.76
Joining the stem cell maintenance squad. Blood (2011) 0.75
Forward RNAi screens in human stem cells. Methods Mol Biol (2010) 0.75