Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men.

PubWeight™: 1.02‹?› | Rank: Top 15%

🔗 View Article (PMID 22367966)

Published in Hum Mol Genet on February 24, 2012

Authors

Xiaoling Lin1, Daru Lu, Yong Gao, Sha Tao, Xiaobo Yang, Junjie Feng, Aihua Tan, Haiying Zhang, Yanling Hu, Xue Qin, Seong-Tae Kim, Tao Peng, Li Li, Linjian Mo, Shijun Zhang, Jeffrey M Trent, Zengnan Mo, S Lilly Zheng, Jianfeng Xu, Jielin Sun

Author Affiliations

1: Fudan Institute of Urology, Huashan Hospital, School of Life Sciences, Fudan University, Shanghai, China.

Articles citing this

Distribution and medical impact of loss-of-function variants in the Finnish founder population. PLoS Genet (2014) 2.89

Applying personal genetic data to injury risk assessment in athletes. PLoS One (2015) 1.42

Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nat Commun (2015) 1.23

Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets. PLoS Genet (2013) 1.04

Systems Epidemiology: A New Direction in Nutrition and Metabolic Disease Research. Curr Nutr Rep (2013) 0.87

CLYBL is a polymorphic human enzyme with malate synthase and β-methylmalate synthase activity. Hum Mol Genet (2013) 0.81

Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial. Front Public Health (2014) 0.79

Transcriptomic profile reveals gender-specific molecular mechanisms driving multiple sclerosis progression. PLoS One (2014) 0.79

Genetic variations affecting serum carcinoembryonic antigen levels and status of regional lymph nodes in patients with sporadic colorectal cancer from Southern China. PLoS One (2014) 0.78

A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin. Am J Hum Genet (2016) 0.77

Genetic determinants of serum vitamin B12 and their relation to body mass index. Eur J Epidemiol (2016) 0.76

A genetic variant in vitamin B12 metabolic genes that reduces the risk of congenital heart disease in Han Chinese populations. PLoS One (2014) 0.75

Micronutrient deficiencies in patients with chronic atrophic autoimmune gastritis: A review. World J Gastroenterol (2017) 0.75

Opportunism: a panacea for implementation of whole-genome sequencing studies in nutrigenomics research? Genes Nutr (2014) 0.75

Articles by these authors

The diploid genome sequence of an Asian individual. Nature (2008) 46.29

A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med (2003) 26.05

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08

Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18

Direct multiplexed measurement of gene expression with color-coded probe pairs. Nat Biotechnol (2008) 15.90

The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76

Cumulative association of five genetic variants with prostate cancer. N Engl J Med (2008) 15.34

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev (2007) 13.05

Diverse somatic mutation patterns and pathway alterations in human cancers. Nature (2010) 10.83

High frequency of BRAF mutations in nevi. Nat Genet (2002) 9.95

TEAD mediates YAP-dependent gene induction and growth control. Genes Dev (2008) 9.88

Inflammation in prostate carcinogenesis. Nat Rev Cancer (2007) 9.08

Regulation of TORC1 by Rag GTPases in nutrient response. Nat Cell Biol (2008) 8.92

The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94

ZDOCK: an initial-stage protein-docking algorithm. Proteins (2003) 7.52

Gene discovery and annotation using LCM-454 transcriptome sequencing. Genome Res (2006) 7.10

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08

A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Hum Mol Genet (2003) 6.82

Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer. Nat Med (2009) 6.61

Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination. Vaccine (2009) 6.30

PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res (2003) 6.19

Distinctive chromatin in human sperm packages genes for embryo development. Nature (2009) 6.18

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet (2008) 6.10

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev (2010) 6.05

SNP discovery via 454 transcriptome sequencing. Plant J (2007) 5.92

MicroRNA-mediated conversion of human fibroblasts to neurons. Nature (2011) 5.59

Germline mutations in HOXB13 and prostate-cancer risk. N Engl J Med (2012) 5.49

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev (2010) 5.38

The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. Cancer Cell (2002) 5.23

A porous supramolecular architecture from a copper(II) coordination polymer with a 3D four-connected 8(6) net. Inorg Chem (2003) 5.16

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol (2007) 5.09

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med (2007) 4.95

Stability of the regulatory T cell lineage in vivo. Science (2010) 4.89

Two genome-wide association studies of aggressive prostate cancer implicate putative prostate tumor suppressor gene DAB2IP. J Natl Cancer Inst (2007) 4.85

Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med (2007) 4.80

Advancing translational research with the Semantic Web. BMC Bioinformatics (2007) 4.38

The Plasmodium genome database. Nature (2002) 4.36

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Mol Cell Biol (2002) 4.27

Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans. J Natl Cancer Inst (2007) 4.24

Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat Rev Drug Discov (2009) 4.12

Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisition. Nat Med (2009) 4.03

Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood (2003) 3.98

Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. Am J Clin Nutr (2004) 3.96

RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases. Nat Genet (2002) 3.87

Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements. Nat Genet (2010) 3.83

Germline gain-of-function mutations in SOS1 cause Noonan syndrome. Nat Genet (2006) 3.81

Common sequence variants on 20q11.22 confer melanoma susceptibility. Nat Genet (2008) 3.79

Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat Genet (2009) 3.76

Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol (2006) 3.75

Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell (2002) 3.71

Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med (2002) 3.68

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev (2012) 3.48

Mutations in SLC20A2 link familial idiopathic basal ganglia calcification with phosphate homeostasis. Nat Genet (2012) 3.34

ToxoDB: accessing the Toxoplasma gondii genome. Nucleic Acids Res (2003) 3.24

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition. J Biol Chem (2007) 3.24

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med (2012) 3.21

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev (2011) 3.15

Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12. Nat Genet (2008) 3.14

A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol (2010) 3.09

Gene density, transcription, and insulators contribute to the partition of the Drosophila genome into physical domains. Mol Cell (2012) 3.08

Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol (2003) 3.02

Acetylation of Smc3 by Eco1 is required for S phase sister chromatid cohesion in both human and yeast. Mol Cell (2008) 3.01

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma. Nature (2011) 2.96

Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype. Virology (2002) 2.96

Genetic evidence supports demic diffusion of Han culture. Nature (2004) 2.92

Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol (2012) 2.91

The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop. Genet Med (2009) 2.91

Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity (2004) 2.89

A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet (2011) 2.85

Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome. Immunity (2009) 2.84

Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol (2009) 2.84

Alpha-methylacyl-CoA racemase: a new molecular marker for prostate cancer. Cancer Res (2002) 2.84

Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet (2002) 2.76

Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy. Cancer Res (2011) 2.71

Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet (2011) 2.70

Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70

A highly sensitive CMOS digital Hall sensor for low magnetic field applications. Sensors (Basel) (2012) 2.69

Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia. Blood (2006) 2.69

Mutations in myosin light chain kinase cause familial aortic dissections. Am J Hum Genet (2010) 2.67