Published in J Biol Chem on February 27, 2012
Regulators of G protein signaling RGS7 and RGS11 determine the onset of the light response in ON bipolar neurons. Proc Natl Acad Sci U S A (2012) 1.26
Gβ3 is required for normal light ON responses and synaptic maintenance. J Neurosci (2012) 1.10
GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes. J Cell Biol (2012) 1.06
Mouse b-wave mutants. Doc Ophthalmol (2014) 0.97
GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells. J Neurosci (2014) 0.88
Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons. Invest Ophthalmol Vis Sci (2013) 0.85
Changes in retinal function and morphology are early clinical signs of disease in cattle with bovine spongiform encephalopathy. PLoS One (2015) 0.83
Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements. Invest Ophthalmol Vis Sci (2014) 0.78
G protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalization. PLoS One (2014) 0.76
Lack of mGluR6-related cascade elements leads to retrograde trans-synaptic effects on rod photoreceptor synapses via matrix-associated proteins. Eur J Neurosci (2016) 0.76
Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior. Elife (2015) 0.76
A Naturally Occurring Canine Model of Autosomal Recessive Congenital Stationary Night Blindness. PLoS One (2015) 0.76
Intermolecular Interaction between Anchoring Subunits Specify Subcellular Targeting and Function of RGS Proteins in Retina ON-Bipolar Neurons. J Neurosci (2016) 0.75
G protein signaling in the retina and beyond: the Cogan lecture. Invest Ophthalmol Vis Sci (2014) 0.75
An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina. PLoS One (2013) 0.75
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A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated with Reduced Energy Expenditure in American Indians. Diabetes (2017) 0.75
GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. Annu Rev Biochem (2000) 5.84
RGS expression rate-limits recovery of rod photoresponses. Neuron (2006) 3.48
Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1. Nature (2000) 3.11
TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells. Proc Natl Acad Sci U S A (2009) 2.27
Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5. Proc Natl Acad Sci U S A (2003) 2.25
Phototransduction in mouse rods and cones. Pflugers Arch (2007) 2.23
TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade. Proc Natl Acad Sci U S A (2009) 2.20
A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits. Proc Natl Acad Sci U S A (1998) 1.94
A naturally occurring mouse model of X-linked congenital stationary night blindness. Invest Ophthalmol Vis Sci (1998) 1.76
The metabotropic receptor mGluR6 may signal through G(o), but not phosphodiesterase, in retinal bipolar cells. J Neurosci (1999) 1.66
Live cell analysis of G protein beta5 complex formation, function, and targeting. Mol Pharmacol (2007) 1.62
Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells. J Neurosci (2007) 1.60
How vision begins: an odyssey. Proc Natl Acad Sci U S A (2008) 1.59
A fifth member of the mammalian G-protein beta-subunit family. Expression in brain and activation of the beta 2 isotype of phospholipase C. J Biol Chem (1994) 1.52
Crystal structure of the multifunctional Gbeta5-RGS9 complex. Nat Struct Mol Biol (2008) 1.52
Identification of the gene and the mutation responsible for the mouse nob phenotype. Invest Ophthalmol Vis Sci (2003) 1.47
A novel form of the G protein beta subunit Gbeta5 is specifically expressed in the vertebrate retina. J Biol Chem (1996) 1.42
Rhodopsin-iCre transgenic mouse line for Cre-mediated rod-specific gene targeting. Genesis (2005) 1.40
Retina-specific GTPase accelerator RGS11/G beta 5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons. J Neurosci (2009) 1.38
RGS6, a modulator of parasympathetic activation in heart. Circ Res (2010) 1.32
Gbeta5-RGS complexes co-localize with mGluR6 in retinal ON-bipolar cells. Eur J Neurosci (2007) 1.32
A role for nyctalopin, a small leucine-rich repeat protein, in localizing the TRP melastatin 1 channel to retinal depolarizing bipolar cell dendrites. J Neurosci (2011) 1.24
cGMP-dependent kinase regulates response sensitivity of the mouse on bipolar cell. J Neurosci (2004) 1.21
Localization and differential interaction of R7 RGS proteins with their membrane anchors R7BP and R9AP in neurons of vertebrate retina. Mol Cell Neurosci (2007) 1.19
Two R7 regulator of G-protein signaling proteins shape retinal bipolar cell signaling. J Neurosci (2009) 1.15
RGS7 and -11 complexes accelerate the ON-bipolar cell light response. Invest Ophthalmol Vis Sci (2009) 1.10
Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites. Invest Ophthalmol Vis Sci (2009) 1.08
Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice. J Neurochem (2011) 1.01
The vertebrate phototransduction cascade: amplification and termination mechanisms. Rev Physiol Biochem Pharmacol (2005) 1.00
G protein beta 5 subunit interactions with alpha subunits and effectors. Biochemistry (2000) 0.89
The genome sequence of taurine cattle: a window to ruminant biology and evolution. Science (2009) 8.23
RGS expression rate-limits recovery of rod photoresponses. Neuron (2006) 3.48
Retinal remodeling triggered by photoreceptor degenerations. J Comp Neurol (2003) 3.04
Evidence for two apoptotic pathways in light-induced retinal degeneration. Nat Genet (2002) 2.49
Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. Cancer Res (2006) 2.42
Transducin translocation in rods is triggered by saturation of the GTPase-activating complex. J Neurosci (2007) 2.09
Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects. Am J Physiol Heart Circ Physiol (2007) 1.99
Overexpression of the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) in skeletal muscle repatterns energy metabolism in the mouse. J Biol Chem (2007) 1.85
Mutation of the HEXIM1 gene results in defects during heart and vascular development partly through downregulation of vascular endothelial growth factor. Circ Res (2007) 1.85
Photoreceptor cGMP phosphodiesterase delta subunit (PDEdelta) functions as a prenyl-binding protein. J Biol Chem (2003) 1.80
Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH. Cell Metab (2010) 1.80
D2 dopamine receptors colocalize regulator of G-protein signaling 9-2 (RGS9-2) via the RGS9 DEP domain, and RGS9 knock-out mice develop dyskinesias associated with dopamine pathways. J Neurosci (2005) 1.74
Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells. J Neurosci (2007) 1.60
The DEP domain determines subcellular targeting of the GTPase activating protein RGS9 in vivo. J Neurosci (2003) 1.51
Desmoid tumor: analysis of prognostic factors and outcomes in a surgical series. Ann Surg Oncol (2012) 1.51
Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization. J Biol Chem (2010) 1.45
Rhodopsin-iCre transgenic mouse line for Cre-mediated rod-specific gene targeting. Genesis (2005) 1.40
Prolonged photoresponses and defective adaptation in rods of Gbeta5-/- mice. J Neurosci (2003) 1.38
Subunit dissociation and diffusion determine the subcellular localization of rod and cone transducins. J Neurosci (2007) 1.35
Light-dependent redistribution of visual arrestins and transducin subunits in mice with defective phototransduction. Mol Vis (2003) 1.35
Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2. J Biol Chem (2008) 1.33
RGS6, a modulator of parasympathetic activation in heart. Circ Res (2010) 1.32
GAP-independent termination of photoreceptor light response by excess gamma subunit of the cGMP-phosphodiesterase. J Neurosci (2006) 1.30
Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases. J Neurosci (2007) 1.28
Phosphoenolpyruvate carboxykinase and the critical role of cataplerosis in the control of hepatic metabolism. Nutr Metab (Lond) (2005) 1.25
Trafficking of membrane proteins to cone but not rod outer segments is dependent on heterotrimeric kinesin-II. J Neurosci (2009) 1.21
Role of LPA4/p2y9/GPR23 in negative regulation of cell motility. Mol Biol Cell (2008) 1.20
Novel form of adaptation in mouse retinal rods speeds recovery of phototransduction. J Gen Physiol (2003) 1.20
Long-term results of Phase II study of high dose photon/proton radiotherapy in the management of spine chordomas, chondrosarcomas, and other sarcomas. J Surg Oncol (2014) 1.17
Deactivation of phosphorylated and nonphosphorylated rhodopsin by arrestin splice variants. J Neurosci (2006) 1.16
Transducin activation state controls its light-dependent translocation in rod photoreceptors. J Biol Chem (2005) 1.16
Proton-beam, intensity-modulated, and/or intraoperative electron radiation therapy combined with aggressive anterior surgical resection for retroperitoneal sarcomas. Ann Surg Oncol (2010) 1.11
Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation. Proc Natl Acad Sci U S A (2008) 1.10
Functional redundancy of R7 RGS proteins in ON-bipolar cell dendrites. Invest Ophthalmol Vis Sci (2009) 1.08
Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants. J Biol Chem (2003) 1.07
Nicotinic excitatory postsynaptic potentials in hippocampal CA1 interneurons are predominantly mediated by nicotinic receptors that contain α4 and β2 subunits. Neuropharmacology (2011) 1.07
CCAAT/enhancer-binding protein beta and delta binding to CIITA promoters is associated with the inhibition of CIITA expression in response to Mycobacterium tuberculosis 19-kDa lipoprotein. J Immunol (2007) 1.03
Cardiac angiosarcoma management and outcomes: 20-year single-institution experience. Ann Surg Oncol (2012) 1.03
Optogenetic stimulation of the corticothalamic pathway affects relay cells and GABAergic neurons differently in the mouse visual thalamus. PLoS One (2012) 1.02
Phase II study of neoadjuvant bevacizumab and radiotherapy for resectable soft tissue sarcomas. Int J Radiat Oncol Biol Phys (2010) 1.02
Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice. J Neurochem (2011) 1.01
Proton-based radiotherapy for unresectable or incompletely resected osteosarcoma. Cancer (2011) 1.01
Regulator of G protein signaling 6 mediates doxorubicin-induced ATM and p53 activation by a reactive oxygen species-dependent mechanism. Cancer Res (2011) 1.01
Long-term follow-up of patients treated with neoadjuvant chemotherapy and radiotherapy for large, extremity soft tissue sarcomas. Cancer (2011) 1.00
RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity. J Biol Chem (2004) 0.98
RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6. J Biol Chem (2002) 0.98
Perforated acute appendicitis resulting from appendiceal villous adenoma presenting with small bowel obstruction: a case report. BMC Gastroenterol (2011) 0.98
Regulator of G protein signaling 6 (RGS6) induces apoptosis via a mitochondrial-dependent pathway not involving its GTPase-activating protein activity. J Biol Chem (2010) 0.97
Amyand's hernia with scrotal abscess presenting as acute scrotum. J Chin Med Assoc (2012) 0.95
Relationships between alanine aminotransferase levels, abnormal liver echogenicity, and metabolic syndrome. J Am Board Fam Med (2011) 0.94
β-Catenin mutation status and outcomes in sporadic desmoid tumors. Oncologist (2013) 0.94
Regulator of G protein signaling 6 (RGS6) protein ensures coordination of motor movement by modulating GABAB receptor signaling. J Biol Chem (2011) 0.93
Japanese encephalitis virus non-coding RNA inhibits activation of interferon by blocking nuclear translocation of interferon regulatory factor 3. Vet Microbiol (2013) 0.93
Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration. Proc Natl Acad Sci U S A (2013) 0.92
G-protein inactivator RGS6 mediates myocardial cell apoptosis and cardiomyopathy caused by doxorubicin. Cancer Res (2013) 0.92
The relationship between thyroid function and bone mineral density in euthyroid healthy subjects in Taiwan. Endocr Res (2011) 0.92
In vitro evidence for role of ERK, p38, and JNK in exocrine pancreatic cytokine production. J Gastrointest Surg (2006) 0.91
Rod outer segment retinol formation is independent of Abca4, arrestin, rhodopsin kinase, and rhodopsin palmitylation. Invest Ophthalmol Vis Sci (2011) 0.91
Mild heat and proteotoxic stress promote unique subcellular trafficking and nucleolar accumulation of RGS6 and other RGS proteins. Role of the RGS domain in stress-induced trafficking of RGS proteins. J Biol Chem (2003) 0.90
The relationship between slow photoresponse recovery rate and temporal resolution of vision. J Neurosci (2012) 0.90
Multiple penile schwannomas and their magnetic resonance imaging characteristics. J Androl (2011) 0.90
RGS12TS-S localizes at nuclear matrix-associated subnuclear structures and represses transcription: structural requirements for subnuclear targeting and transcriptional repression. Mol Cell Biol (2002) 0.89
Bile-pancreatic juice exclusion promotes Akt/NF-kappaB activation and chemokine production in ligation-induced acute pancreatitis. J Gastrointest Surg (2006) 0.89
Phototransduction in a transgenic mouse model of Nougaret night blindness. J Neurosci (2006) 0.88
Cellular oxidant stress and advanced glycation endproducts of albumin: caveats of the dichlorofluorescein assay. Arch Biochem Biophys (2002) 0.87
Neoadjuvant chemoradiotherapy for patients with high-risk extremity and truncal sarcomas: a 10-year single institution retrospective study. Eur J Cancer (2012) 0.87
Identification of conserved regulatory elements in mammalian promoter regions: a case study using the PCK1 promoter. Genomics Proteomics Bioinformatics (2008) 0.86
Role of sentinel lymph node biopsy in the staging of synovial, epithelioid, and clear cell sarcomas. Ann Surg Oncol (2009) 0.86
RGS Proteins in Heart: Brakes on the Vagus. Front Physiol (2012) 0.86
Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors. J Neurosci (2013) 0.85
Association between thyroid function and metabolic syndrome in elderly subjects. J Am Geriatr Soc (2010) 0.85
Synaptic muscarinic response types in hippocampal CA1 interneurons depend on different levels of presynaptic activity and different muscarinic receptor subtypes. Neuropharmacology (2013) 0.84
Magnetic mesocrystal-assisted magnetoresistance in manganite. Nano Lett (2014) 0.84
Extra-adrenal paraganglioma of the prostate. Can Urol Assoc J (2013) 0.84
Regulator of g protein signaling 3 modulates wnt5b calcium dynamics and somite patterning. PLoS Genet (2010) 0.83
Predictive value of serum uric acid levels for the diagnosis of metabolic syndrome in adolescents. J Pediatr (2012) 0.83
Regulator of G protein signaling 6 is a novel suppressor of breast tumor initiation and progression. Carcinogenesis (2013) 0.83
Monascuspiloin induces apoptosis and autophagic cell death in human prostate cancer cells via the Akt and AMPK signaling pathways. J Agric Food Chem (2012) 0.83
On the mechanisms of arrhythmias in the myocardium of mXinalpha-deficient murine left atrial-pulmonary veins. Life Sci (2008) 0.82
Elevated fasting glucose levels within normal range are associated with an increased risk of metabolic syndrome in older women. Eur J Intern Med (2013) 0.82
Prognostic significance of treatment-induced pathologic necrosis in extremity and truncal soft tissue sarcoma after neoadjuvant chemoradiotherapy. Cancer (2014) 0.81
Role of post-operative radiation boost for soft tissue sarcomas with positive margins following pre-operative radiation and surgery. J Surg Oncol (2014) 0.81
Signal transducer and activator of transcription 3 as molecular therapy for non-small-cell lung cancer. J Thorac Oncol (2014) 0.81
Function of phosphoenolpyruvate carboxykinase in mammary gland epithelial cells. J Lipid Res (2011) 0.81
Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis. FASEB J (2014) 0.81
Monascuspiloin enhances the radiation sensitivity of human prostate cancer cells by stimulating endoplasmic reticulum stress and inducing autophagy. PLoS One (2012) 0.81
Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism. J Neurosci (2010) 0.81
MRI surveillance following treatment of extremity soft tissue sarcoma. J Surg Oncol (2013) 0.81
Efficacy of Proton Beam Therapy in the Treatment of Ewing's Sarcoma of the Paranasal Sinuses and Anterior Skull Base. Skull Base (2009) 0.80
Mesenteric phlebosclerosis: an unexpected cause of abdominal pain. J Gastrointestin Liver Dis (2012) 0.80
Retroperitoneal sarcoma (RPS) high risk gross tumor volume boost (HR GTV boost) contour delineation agreement among NRG sarcoma radiation and surgical oncologists. Ann Surg Oncol (2015) 0.79
Baculovirus transduction of rat articular chondrocytes: roles of cell cycle. J Gene Med (2007) 0.79
Is lower uric acid level better? A combined cross-sectional and longitudinal study in the elderly. Endocrine (2014) 0.79
Evaluation of second phase insulin secretion with simple surrogates derived from the mixed meal tolerance test in patients with type 2 diabetes. Endocr J (2013) 0.79