Published in Aging Cell on April 05, 2012
Comet-FISH with strand-specific probes reveals transcription-coupled repair of 8-oxoGuanine in human cells. Nucleic Acids Res (2013) 1.13
Oxidative DNA damage and nucleotide excision repair. Antioxid Redox Signal (2012) 0.99
Blinded by the UV light: how the focus on transcription-coupled NER has distracted from understanding the mechanisms of Cockayne syndrome neurologic disease. DNA Repair (Amst) (2013) 0.99
DNA repair diseases: What do they tell us about cancer and aging? Genet Mol Biol (2014) 0.98
Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies. Oxid Med Cell Longev (2014) 0.95
Diseases associated with defective responses to DNA damage. Cold Spring Harb Perspect Biol (2012) 0.94
Mitochondrial deficiency in Cockayne syndrome. Mech Ageing Dev (2013) 0.92
Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1. Nucleic Acids Res (2013) 0.89
Mitochondrial reactive oxygen species are scavenged by Cockayne syndrome B protein in human fibroblasts without nuclear DNA damage. Proc Natl Acad Sci U S A (2014) 0.86
Mitochondrial DNA damage induced autophagy, cell death, and disease. Front Biosci (Landmark Ed) (2016) 0.84
Cockayne syndrome-derived neurons display reduced synapse density and altered neural network synchrony. Hum Mol Genet (2016) 0.81
Photosensitivity syndrome brings to light a new transcription-coupled DNA repair cofactor. Nat Genet (2012) 0.81
UVSSA and USP7, a new couple in transcription-coupled DNA repair. Chromosoma (2013) 0.81
The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis. Cell Death Dis (2016) 0.80
Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome. Proc Natl Acad Sci U S A (2015) 0.79
The CSB chromatin remodeler and CTCF architectural protein cooperate in response to oxidative stress. Nucleic Acids Res (2015) 0.77
Oxidative and energy metabolism as potential clues for clinical heterogeneity in nucleotide excision repair disorders. J Invest Dermatol (2014) 0.76
Cockayne syndrome: Clinical features, model systems and pathways. Ageing Res Rev (2016) 0.76
Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA. Proc Natl Acad Sci U S A (2016) 0.75
Lack of XPC leads to a shift between respiratory complexes I and II but sensitizes cells to mitochondrial stress. Sci Rep (2017) 0.75
Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods (2005) 6.23
Glycolytic enzymes can modulate cellular life span. Cancer Res (2005) 3.78
Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol Biol (2006) 2.87
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Mol Cell Biol (2004) 2.65
Energy metabolism in human pluripotent stem cells and their differentiated counterparts. PLoS One (2011) 2.64
A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A. Nat Genet (2004) 2.54
Prokaryotic nucleotide excision repair: the UvrABC system. Chem Rev (2006) 2.37
The INTERPHONE study: design, epidemiological methods, and description of the study population. Eur J Epidemiol (2007) 2.30
Multicenter comparative multimodality surveillance of women at genetic-familial high risk for breast cancer (HIBCRIT study): interim results. Radiology (2007) 2.22
Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. Blood (2004) 2.19
Microsatellite instability as a marker of prognosis and response to therapy: a meta-analysis of colorectal cancer survival data. Eur J Cancer (2010) 2.16
Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients. Mol Cell (2003) 2.12
Alterations of choline phospholipid metabolism in ovarian tumor progression. Cancer Res (2005) 2.11
Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. DNA Repair (Amst) (2008) 2.02
Integrating phenotypic and expression profiles to map arsenic-response networks. Genome Biol (2004) 1.90
High-mobility group box 1 is essential for mitochondrial quality control. Cell Metab (2011) 1.89
Adipose tissue and adipocytes support tumorigenesis and metastasis. Biochim Biophys Acta (2013) 1.85
Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD. PLoS Biol (2008) 1.81
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair. Nature (2011) 1.80
Genome-wide expression profile of sporadic gastric cancers with microsatellite instability. Eur J Cancer (2008) 1.78
Role of mitochondria in toxic oxidative stress. Mol Interv (2005) 1.76
Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells. Cancer Res (2010) 1.65
DNA nucleotide excision repair-dependent signaling to checkpoint activation. Proc Natl Acad Sci U S A (2006) 1.64
Xeroderma pigmentosum. Orphanet J Rare Dis (2011) 1.62
Alterations in bioenergetics due to changes in mitochondrial DNA copy number. Methods (2010) 1.62
NIEHS extramural global environmental health portfolio: opportunities for collaboration. Environ Health Perspect (2008) 1.61
New functions of XPC in the protection of human skin cells from oxidative damage. EMBO J (2006) 1.60
Mitochondrial dysfunction in neurodegenerative diseases and cancer. Environ Mol Mutagen (2010) 1.60
Mitochondrial DNA repair and aging. Mutat Res (2002) 1.60
Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways. DNA Repair (Amst) (2006) 1.59
pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity. Int J Cancer (2010) 1.58
The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool. Curr Biol (2002) 1.53
Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia. Am J Hum Genet (2013) 1.52
Structural basis for DNA recognition and processing by UvrB. Nat Struct Mol Biol (2006) 1.51
Cell sorting experiments link persistent mitochondrial DNA damage with loss of mitochondrial membrane potential and apoptotic cell death. J Biol Chem (2002) 1.49
Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species. PLoS One (2011) 1.48
Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells. J Biol Chem (2010) 1.46
The beta -hairpin motif of UvrB is essential for DNA binding, damage processing, and UvrC-mediated incisions. J Biol Chem (2001) 1.46
Reduced level of the repair/transcription factor TFIIH in trichothiodystrophy. Hum Mol Genet (2002) 1.46
True XP group E patients have a defective UV-damaged DNA binding protein complex and mutations in DDB2 which reveal the functional domains of its p48 product. Hum Mol Genet (2003) 1.45
Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans. Genome Biol (2007) 1.41
Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. Mol Cell (2010) 1.40
Metabolic symbiosis in cancer: refocusing the Warburg lens. Mol Carcinog (2012) 1.40
Measuring oxidative mtDNA damage and repair using quantitative PCR. Methods Mol Biol (2002) 1.40
Environmental burden of disease in Europe: assessing nine risk factors in six countries. Environ Health Perspect (2014) 1.39
Multicenter surveillance of women at high genetic breast cancer risk using mammography, ultrasonography, and contrast-enhanced magnetic resonance imaging (the high breast cancer risk italian 1 study): final results. Invest Radiol (2011) 1.39
Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. Nat Genet (2012) 1.38
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage. Aging Cell (2004) 1.37
Terminally differentiated muscle cells are defective in base excision DNA repair and hypersensitive to oxygen injury. Proc Natl Acad Sci U S A (2007) 1.34
Air pollution and lung function among susceptible adult subjects: a panel study. Environ Health (2006) 1.33
Mitochondrial localization of telomerase as a determinant for hydrogen peroxide-induced mitochondrial DNA damage and apoptosis. Hum Mol Genet (2006) 1.32
Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: cellular model of pathology. PLoS Genet (2010) 1.32
Structural insights into the first incision reaction during nucleotide excision repair. EMBO J (2005) 1.30
Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins. Nucleic Acids Res (2007) 1.30
Mitochondrial hyperfusion induced by loss of the fission protein Drp1 causes ATM-dependent G2/M arrest and aneuploidy through DNA replication stress. J Cell Sci (2012) 1.30
Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells. J Biol Chem (2009) 1.29
Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases. Cancer Res (2004) 1.29
The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells. Mol Cell Biol (2004) 1.29
Conceptual model of comprehensive research metrics for improved human health and environment. Environ Health Perspect (2008) 1.29
Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand. J Immunol (2002) 1.28
Recall bias in the assessment of exposure to mobile phones. J Expo Sci Environ Epidemiol (2008) 1.27
Immune surveillance properties of human NK cell-derived exosomes. J Immunol (2012) 1.26
A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage. Proc Natl Acad Sci U S A (2009) 1.26
Somatic PTPN11 mutations in childhood acute myeloid leukaemia. Br J Haematol (2005) 1.25
Reduction in frataxin causes progressive accumulation of mitochondrial damage. Hum Mol Genet (2003) 1.24
Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer. Mutagenesis (2010) 1.23
Double-strand break formation during nucleotide excision repair of a DNA interstrand cross-link. Biochemistry (2009) 1.23
Two new XPD patients compound heterozygous for the same mutation demonstrate diverse clinical features. J Invest Dermatol (2005) 1.21
UvrB domain 4, an autoinhibitory gate for regulation of DNA binding and ATPase activity. J Biol Chem (2006) 1.20
Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proc Natl Acad Sci U S A (2002) 1.20
Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells. Cancer Res (2008) 1.19
Initiation of repair of DNA-polypeptide cross-links by the UvrABC nuclease. Biochemistry (2005) 1.19
Asbestos induces mitochondrial DNA damage and dysfunction linked to the development of apoptosis. Am J Physiol Lung Cell Mol Physiol (2003) 1.18
Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair. J Biol Chem (2011) 1.18
Inhibiting systemic autophagy during interleukin 2 immunotherapy promotes long-term tumor regression. Cancer Res (2012) 1.17
Inhibition of phosphatidylcholine-specific phospholipase C downregulates HER2 overexpression on plasma membrane of breast cancer cells. Breast Cancer Res (2010) 1.16
p8/TTD-A as a repair-specific TFIIH subunit. Mol Cell (2006) 1.16
Prokaryotic nucleotide excision repair. Cold Spring Harb Perspect Biol (2013) 1.16
Mitochondrial and nuclear DNA defects in Saccharomyces cerevisiae with mutations in DNA polymerase gamma associated with progressive external ophthalmoplegia. Hum Mol Genet (2005) 1.16
The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase beta defective mammalian cells. Nucleic Acids Res (2005) 1.16
Probing for DNA damage with β-hairpins: similarities in incision efficiencies of bulky DNA adducts by prokaryotic and human nucleotide excision repair systems in vitro. DNA Repair (Amst) (2011) 1.15
Children's health in Latin America: the influence of environmental exposures. Environ Health Perspect (2014) 1.15
Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair. EMBO J (2004) 1.15
Glycolytic phenotype and AMP kinase modify the pathologic response of tumor xenografts to VEGF neutralization. Cancer Res (2011) 1.14
MR evaluation of response to targeted treatment in cancer cells. NMR Biomed (2011) 1.14
Transcription-associated breaks in xeroderma pigmentosum group D cells from patients with combined features of xeroderma pigmentosum and Cockayne syndrome. Mol Cell Biol (2005) 1.13
Analysis of DNA damage and repair in nuclear and mitochondrial DNA of animal cells using quantitative PCR. Methods Mol Biol (2012) 1.13
Risk factors for reduced glomerular filtration rate in a Nicaraguan community affected by Mesoamerican nephropathy. MEDICC Rev (2014) 1.12