Published in Clin Epigenetics on February 27, 2012
Gut dysbiosis is linked to hypertension. Hypertension (2015) 1.28
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Histone deacetylase inhibition in the treatment of acute myeloid leukemia: the effects of valproic acid on leukemic cells, and the clinical and experimental evidence for combining valproic acid with other antileukemic agents. Clin Epigenetics (2013) 0.93
Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. PLoS One (2013) 0.92
Butyrate histone deacetylase inhibitors. Biores Open Access (2012) 0.90
Emerging roles of lactic acid bacteria in protection against colorectal cancer. World J Gastroenterol (2014) 0.89
The Potential Therapeutic Efficacy of Lactobacillus GG in Children with Food Allergies. Pharmaceuticals (Basel) (2012) 0.89
Role of the Gut Microbiome in Obstructive Sleep Apnea-Induced Hypertension. Hypertension (2015) 0.88
The influence of early life nutrition on epigenetic regulatory mechanisms of the immune system. Nutrients (2014) 0.87
Probiotics and Alcoholic Liver Disease: Treatment and Potential Mechanisms. Gastroenterol Res Pract (2015) 0.85
Gut microbiota as potential therapeutic target for the treatment of cow's milk allergy. Nutrients (2013) 0.85
The Significance of the Enteric Microbiome on the Development of Childhood Disease: A Review of Prebiotic and Probiotic Therapies in Disorders of Childhood. Clin Med Insights Pediatr (2016) 0.84
Mechanistic insights into the role of microRNAs in cancer: influence of nutrient crosstalk. Front Genet (2012) 0.83
Genotype-dependency of butyrate efficacy in children with congenital chloride diarrhea. Orphanet J Rare Dis (2013) 0.82
General Anesthesia Causes Epigenetic Histone Modulation of c-Fos and Brain-derived Neurotrophic Factor, Target Genes Important for Neuronal Development in the Immature Rat Hippocampus. Anesthesiology (2016) 0.80
Transcriptomic Sequencing Reveals a Set of Unique Genes Activated by Butyrate-Induced Histone Modification. Gene Regul Syst Bio (2016) 0.80
Epigenetics and Cellular Metabolism. Genet Epigenet (2016) 0.80
Epigenetics in male reproduction: effect of paternal diet on sperm quality and offspring health. Nat Rev Urol (2016) 0.79
Role of bioactive fatty acids in nonalcoholic fatty liver disease. Nutr J (2016) 0.79
Differential cellular and molecular effects of butyrate and trichostatin a on vascular smooth muscle cells. Pharmaceuticals (Basel) (2012) 0.79
Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats. BMC Gastroenterol (2016) 0.79
Microbiome-Epigenome Interactions and the Environmental Origins of Inflammatory Bowel Diseases. J Pediatr Gastroenterol Nutr (2016) 0.78
Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. Biochim Biophys Acta (2013) 0.78
Effect of partially protected butyrate used as feed additive on growth and intestinal metabolism in sea bream (Sparus aurata). Fish Physiol Biochem (2013) 0.78
Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors. Curr Top Med Chem (2016) 0.77
Calcium butyrate: Anti-inflammatory effect on experimental colitis in rats and antitumor properties. Biomed Rep (2014) 0.76
Microbiota and Neurological Disorders: A Gut Feeling. Biores Open Access (2016) 0.76
The histone deacetylase inhibitor, sodium butyrate, exhibits neuroprotective effects for ischemic stroke in middle-aged female rats. J Neuroinflammation (2016) 0.76
Augmentation of Cationic Antimicrobial Peptide Production with Histone Deacetylase Inhibitors as a Novel Epigenetic Therapy for Bacterial Infections. Antibiotics (Basel) (2015) 0.76
Shifts in the Gut Microbiota Composition Due to Depleted Bone Marrow Beta Adrenergic Signaling Are Associated with Suppressed Inflammatory Transcriptional Networks in the Mouse Colon. Front Physiol (2017) 0.75
Butyrate alleviates high fat diet-induced obesity through activation of adiponectin-mediated pathway and stimulation of mitochondrial function in the skeletal muscle of mice. Oncotarget (2016) 0.75
Epigenetic Regulation of Enteric Neurotransmission by Gut Bacteria. Front Cell Neurosci (2016) 0.75
Effects of supplementation with nondigestible carbohydrates on fecal calprotectin and on epigenetic regulation of SFRP1 expression in the large-bowel mucosa of healthy individuals. Am J Clin Nutr (2017) 0.75
Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells. Redox Biol (2017) 0.75
Histone modifiers and marks define heterogeneous groups of colorectal carcinomas and affect responses to HDAC inhibitors in vitro. Am J Cancer Res (2016) 0.75
Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. PLoS One (2016) 0.75
Alterations in the gut microbiota can elicit hypertension in rats. Physiol Genomics (2016) 0.75
Effects of Non-Starch Polysaccharides on Inflammatory Bowel Disease. Int J Mol Sci (2017) 0.75
Sodium Butyrate and Valproic Acid as Splicing Restoring Agents in Erythroid Cells of β-Thalassemic Patients. Iran J Biotechnol (2016) 0.75
Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A (2003) 59.17
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med (1997) 32.63
Identification of a cancer stem cell in human brain tumors. Cancer Res (2003) 24.02
Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Discov (2006) 14.01
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Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther (2007) 5.47
Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. J Neurosci (2007) 5.02
Apoptotic and autophagic cell death induced by histone deacetylase inhibitors. Proc Natl Acad Sci U S A (2004) 4.20
Specificity of polysaccharide use in intestinal bacteroides species determines diet-induced microbiota alterations. Cell (2010) 3.70
Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells (2010) 3.53
Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study. Lancet (2003) 3.53
Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine. FEMS Microbiol Lett (2009) 3.48
Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes (2009) 3.17
Modulation of long-term memory for object recognition via HDAC inhibition. Proc Natl Acad Sci U S A (2009) 2.81
A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders. N Engl J Med (1993) 2.76
Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease. Blood (1999) 2.66
Intestinal barrier function: molecular regulation and disease pathogenesis. J Allergy Clin Immunol (2009) 2.63
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease. J Biol Chem (2004) 2.43
The butyrate story: old wine in new bottles? Curr Opin Clin Nutr Metab Care (2004) 2.28
Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy. Clin Epigenetics (2010) 2.26
Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol (2011) 2.03
Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling. Oncogene (2002) 2.02
Histone deacetylase inhibitors: molecular mechanisms of action and clinical trials as anti-cancer drugs. Am J Transl Res (2010) 2.01
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Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. Gut (2003) 1.97
Dietary histone deacetylase inhibitors: from cells to mice to man. Semin Cancer Biol (2007) 1.93
Topical butyrate improves efficacy of 5-ASA in refractory distal ulcerative colitis: results of a multicentre trial. Eur J Clin Invest (2003) 1.86
The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain. J Neurochem (2009) 1.53
Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori. Gastroenterology (2003) 1.51
Diet induced epigenetic changes and their implications for health. Acta Physiol (Oxf) (2011) 1.43
Histone-deacetylase inhibitors induce the cathelicidin LL-37 in gastrointestinal cells. Mol Immunol (2004) 1.32
Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenetics (2011) 1.31
Current and future pharmacological treatment strategies in X-linked adrenoleukodystrophy. Brain Pathol (2010) 1.27
Butyrate and other short-chain fatty acids as modulators of immunity: what relevance for health? Curr Opin Clin Nutr Metab Care (2010) 1.27
Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat Res (2009) 1.27
Increasing fecal butyrate in ulcerative colitis patients by diet: controlled pilot study. Inflamm Bowel Dis (2003) 1.16
Congenital diarrheal disorders: improved understanding of gene defects is leading to advances in intestinal physiology and clinical management. J Pediatr Gastroenterol Nutr (2010) 1.16
'Gut health': a new objective in medicine? BMC Med (2011) 1.15
Butyrate and Wnt signaling: a possible solution to the puzzle of dietary fiber and colon cancer risk? Cell Cycle (2008) 1.14
Sodium butyrate up-regulates cathelicidin gene expression via activator protein-1 and histone acetylation at the promoter region in a human lung epithelial cell line, EBC-1. Mol Immunol (2006) 1.10
Phase II trial of the histone deacetylase inhibitor pivaloyloxymethyl butyrate (Pivanex, AN-9) in advanced non-small cell lung cancer. Lung Cancer (2004) 1.10
Dietary manipulation of histone structure and function. Annu Rev Nutr (2008) 1.02
Effects of histone deacetylase inhibitors on HIF-1. Cell Cycle (2006) 1.01
Modulation of xenobiotic metabolising enzymes by anticarcinogens -- focus on glutathione S-transferases and their role as targets of dietary chemoprevention in colorectal carcinogenesis. Mutat Res (2005) 1.01
Epigenetic mechanisms elicited by nutrition in early life. Nutr Res Rev (2011) 1.00
Butyrate as an effective treatment of congenital chloride diarrhea. Gastroenterology (2004) 0.98
The significance of the gut barrier in disease. Gut (2008) 0.98
Epigenome targeting by probiotic metabolites. Gut Pathog (2010) 0.92
Butyrate, an HDAC inhibitor, stimulates interplay between different posttranslational modifications of histone H3 and differently alters G1-specific cell cycle proteins in vascular smooth muscle cells. Biomed Pharmacother (2010) 0.89
Epigenetic regulation of the immune system in health and disease. Tissue Antigens (2010) 0.89
Gene expression analysis of a human enterocyte cell line reveals downregulation of cholesterol biosynthesis in response to short-chain fatty acids. IUBMB Life (2008) 0.86
Future pharmacological treatment of cystic fibrosis. Respiration (2000) 0.84
Sodium butyrate inhibits the self-renewal capacity of endometrial tumor side-population cells by inducing a DNA damage response. Mol Cancer Ther (2011) 0.83
Formula selection for management of children with cow's milk allergy influences the rate of acquisition of tolerance: a prospective multicenter study. J Pediatr (2013) 2.08
Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol (2011) 2.03
Effect of Lactobacillus GG on tolerance acquisition in infants with cow's milk allergy: a randomized trial. J Allergy Clin Immunol (2011) 1.97
Epigenetic mechanisms elicited by nutrition in early life. Nutr Res Rev (2011) 1.00
Congenital diarrheal disorders: an updated diagnostic approach. Int J Mol Sci (2012) 0.96
The Potential Therapeutic Efficacy of Lactobacillus GG in Children with Food Allergies. Pharmaceuticals (Basel) (2012) 0.89
Gut microbiota as potential therapeutic target for the treatment of cow's milk allergy. Nutrients (2013) 0.85
Crenotherapy modulates the expression of proinflammatory cytokines and immunoregulatory peptides in nasal secretions of children with chronic rhinosinusitis. Am J Rhinol Allergy (2012) 0.83
Effects of a Lactobacillus paracasei B21060 based synbiotic on steatosis, insulin signaling and toll-like receptor expression in rats fed a high-fat diet. J Nutr Biochem (2013) 0.81
The effects of dietary counseling on children with food allergy: a prospective, multicenter intervention study. J Acad Nutr Diet (2014) 0.79
Tolerance to a new free amino acid-based formula in children with IgE or non-IgE-mediated cow's milk allergy: a randomized controlled clinical trial. BMC Pediatr (2013) 0.77
Calcium and vitamin D intakes in children: a randomized controlled trial. BMC Pediatr (2013) 0.76
Amino Acid-based Formula in Cow's Milk Allergy: Long-term Effects on Body Growth and Protein Metabolism. J Pediatr Gastroenterol Nutr (2017) 0.75
Food allergy diagnostic practice in Italian children. J Allergy Clin Immunol (2012) 0.75