Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators.

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Published in Bioorg Med Chem Lett on March 01, 2012

Authors

Martin Pettersson1, Douglas S Johnson, Chakrapani Subramanyam, Kelly R Bales, Christopher W am Ende, Benjamin A Fish, Michael E Green, Gregory W Kauffman, Ricardo Lira, Patrick B Mullins, Thayalan Navaratnam, Subas M Sakya, Cory M Stiff, Tuan P Tran, Beth C Vetelino, Longfei Xie, Liming Zhang, Leslie R Pustilnik, Kathleen M Wood, Christopher J O'Donnell

Author Affiliations

1: Neuroscience Medicinal Chemistry, Pfizer Worldwide Research and Development, Groton, CT 06340, USA. martin.pettersson@pfizer.com

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