Published in Theriogenology on March 22, 2012
The sequence of the human genome. Science (2001) 101.55
Translational control is required for the unfolded protein response and in vivo glucose homeostasis. Mol Cell (2001) 11.21
FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell (1994) 7.66
Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. J Biol Chem (2001) 7.03
LDL-receptor-related proteins in Wnt signal transduction. Nature (2000) 6.94
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science (2000) 6.44
KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma. Nat Med (1996) 5.96
Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. J Virol (2000) 5.44
gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand. J Exp Med (1998) 5.24
Cre-mediated gene deletion in the mammary gland. Nucleic Acids Res (1997) 4.89
American College of Rheumatology classification criteria for Sjögren's syndrome: a data-driven, expert consensus approach in the Sjögren's International Collaborative Clinical Alliance cohort. Arthritis Care Res (Hoboken) (2012) 4.82
Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity. Science (2011) 4.72
A 1.5 million-base pair inversion polymorphism in families with Williams-Beuren syndrome. Nat Genet (2001) 4.58
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression. Proc Natl Acad Sci U S A (1994) 4.44
Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013. Euro Surveill (2013) 4.37
Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature (2000) 4.31
The effects of frequent nocturnal home hemodialysis: the Frequent Hemodialysis Network Nocturnal Trial. Kidney Int (2011) 4.27
Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease. Nat Med (2000) 4.18
Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay. Mol Cell Biol (1996) 4.10
Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science (1994) 3.98
Smoking cessation with and without assistance: a population-based analysis. Am J Prev Med (2000) 3.92
15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. Proc Natl Acad Sci U S A (2000) 3.89
A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas. Oncogene (2006) 3.89
Genome-wide association study of bipolar disorder in European American and African American individuals. Mol Psychiatry (2009) 3.64
High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus. Genes Immun (2007) 3.59
Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron (1998) 3.59
Ballistic 2-d imaging through scattering walls using an ultrafast optical kerr gate. Science (1991) 3.53
ETR2 is an ETR1-like gene involved in ethylene signaling in Arabidopsis. Proc Natl Acad Sci U S A (1998) 3.48
Assembly of the mitochondrial membrane system: sequences of yeast mitochondrial valine and an unusual threonine tRNA gene. Cell (1979) 3.39
Pyrazole ligands: structure-affinity/activity relationships and estrogen receptor-alpha-selective agonists. J Med Chem (2000) 3.34
AAPM protocol for 40-300 kV x-ray beam dosimetry in radiotherapy and radiobiology. Med Phys (2001) 3.32
Estrogen receptor-beta potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues. J Med Chem (2001) 3.24
Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain. Cell (1998) 3.22
RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae. Genes Dev (1993) 3.18
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radic Biol Med (2005) 3.13
Codon recognition rules in yeast mitochondria. Proc Natl Acad Sci U S A (1980) 3.11
High-dose intravenous immune globulin for stiff-person syndrome. N Engl J Med (2001) 3.04
Characterization of ionomycin as a calcium ionophore. J Biol Chem (1978) 3.00
Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013. Euro Surveill (2013) 2.99
Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease. Nature (1999) 2.97
Evidence for in vivo but not in vitro expression of a Borrelia burgdorferi outer surface protein F (OspF) homologue. Mol Microbiol (1995) 2.92
Nanostructured high-strength molybdenum alloys with unprecedented tensile ductility. Nat Mater (2013) 2.90
Alcohol drinking and all cancer mortality: a meta-analysis. Ann Oncol (2012) 2.83
Identification of the paromomycin-resistance mutation in the 15 S rRNA gene of yeast mitochondria. J Biol Chem (1982) 2.70
Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function. Oncogene (2007) 2.68
Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities. J Biol Chem (2001) 2.62
Bactericidal activity of deptomycin (LY146032) compared with those of ciprofloxacin, vancomycin, and ampicillin against enterococci as determined by kill-kinetic studies. Antimicrob Agents Chemother (1987) 2.59
Molecular characterization and transcriptional analysis of type 8 capsule genes in Staphylococcus aureus. J Bacteriol (1997) 2.58
Three distinct regions of the murine gammaherpesvirus 68 genome are transcriptionally active in latently infected mice. J Virol (1999) 2.56
Fusion of two novel genes, RBM15 and MKL1, in the t(1;22)(p13;q13) of acute megakaryoblastic leukemia. Nat Genet (2001) 2.55
Orally absorbed reactive glycation products (glycotoxins): an environmental risk factor in diabetic nephropathy. Proc Natl Acad Sci U S A (1997) 2.53
Clinical manifestations and diagnosis of acute pyrethroid poisoning. Arch Toxicol (1989) 2.50
Singleton deletions throughout the genome increase risk of bipolar disorder. Mol Psychiatry (2008) 2.50
Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys. Neurotoxicol Teratol (2011) 2.41
The skeletal muscle calcium release channel: coupled O2 sensor and NO signaling functions. Cell (2000) 2.41
Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus. Nat Med (1998) 2.38
The gut as a portal of entry for bacteremia. Role of protein malnutrition. Ann Surg (1987) 2.38
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1. EMBO J (2001) 2.32
The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing. J Cell Biol (1995) 2.26
Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity (1996) 2.24
NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation. Oncogene (2011) 2.22
The clinical spectrum of anti-GAD antibody-positive patients with stiff-person syndrome. Neurology (2000) 2.20
A clustering approach to multireference alignment of single-particle projections in electron microscopy. J Struct Biol (2010) 2.19
CREB-binding protein sequestration by expanded polyglutamine. Hum Mol Genet (2000) 2.18
Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity. Cell (2000) 2.15
Characterization of human tracheal epithelial cells transformed by an origin-defective simian virus 40. Proc Natl Acad Sci U S A (1988) 2.15
Borrelia burgdorferi supercoiled plasmids encode multicopy tandem open reading frames and a lipoprotein gene family. J Bacteriol (1996) 2.14
Rapid identification of 11 human intestinal Lactobacillus species by multiplex PCR assays using group- and species-specific primers derived from the 16S-23S rRNA intergenic spacer region and its flanking 23S rRNA. FEMS Microbiol Lett (2000) 2.13
Lung cancer proliferation correlates with [F-18]fluorodeoxyglucose uptake by positron emission tomography. Clin Cancer Res (2000) 2.13
Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke. J Natl Cancer Inst (1999) 2.11
Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring (V600E)BRAF. Oncogene (2011) 2.10
Occurrence of both unipolar memory and threshold resistance switching in a NiO film. Phys Rev Lett (2009) 2.10
Cytoplasmic dynein function is essential in Drosophila melanogaster. Genetics (1996) 2.10
Predictors of smoking cessation in U.S. adolescents. Am J Prev Med (1999) 2.09
Dietetic guidelines on food and nutrition in the secondary prevention of cardiovascular disease - evidence from systematic reviews of randomized controlled trials (second update, January 2006). J Hum Nutr Diet (2006) 2.09
Multiple imputation for multivariate data with missing and below-threshold measurements: time-series concentrations of pollutants in the Arctic. Biometrics (2001) 2.05
Use of the UGA terminator as a tryptophan codon in yeast mitochondria. Proc Natl Acad Sci U S A (1979) 2.05
IMPACT trial results should not change current standard of care of 100 days for cytomegalovirus prophylaxis. Am J Transplant (2010) 2.05
Activation of HER4 by heparin-binding EGF-like growth factor stimulates chemotaxis but not proliferation. EMBO J (1997) 2.02
Recombinant influenza A virus vaccines for the pathogenic human A/Hong Kong/97 (H5N1) viruses. J Infect Dis (1999) 2.02
Further characterization of endometrial integrins during the menstrual cycle and in pregnancy. Fertil Steril (1994) 1.99
Regulation of transport of the dopamine D1 receptor by a new membrane-associated ER protein. Nat Cell Biol (2001) 1.99
Smoking, air pollution, and the high rates of lung cancer in Shenyang, China. J Natl Cancer Inst (1989) 1.99
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene (2010) 1.97
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Proc Natl Acad Sci U S A (1999) 1.95
Prevalence of Staphylococcus aureus carrying Panton-Valentine leukocidin genes among isolates from hospitalised patients in China. Clin Microbiol Infect (2008) 1.95
Indoor radon and lung cancer in China. J Natl Cancer Inst (1990) 1.95
Solution structure of the extended neuronal nitric oxide synthase PDZ domain complexed with an associated peptide. Nat Struct Biol (1999) 1.95
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma. Nature (2000) 1.93
Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system. J Cell Biochem (1995) 1.93
Pseudomonas aeruginosa ExoS and ExoT. Rev Physiol Biochem Pharmacol (2004) 1.91
PR39, a peptide regulator of angiogenesis. Nat Med (2000) 1.90
Reverse transcriptase in a clinical strain of Escherichia coli: production of branched RNA-linked msDNA. Science (1989) 1.89
A phospholipid acts as a chaperone in assembly of a membrane transport protein. J Biol Chem (1996) 1.89
Association study of neuregulin 1 gene with schizophrenia. Mol Psychiatry (2003) 1.89
Modified sutureless sclerotomies in pars plana vitrectomy. Am J Ophthalmol (1999) 1.89
Transformation of NIH 3T3 cells by HER3 or HER4 receptors requires the presence of HER1 or HER2. J Biol Chem (1996) 1.87
Effects of pyrethroid insecticides on subjects engaged in packaging pyrethroids. Br J Ind Med (1988) 1.87