Published in Mol Brain on May 20, 2012
Astrocytes, but not microglia, are activated in oxaliplatin and bortezomib-induced peripheral neuropathy in the rat. Neuroscience (2014) 0.91
NFκB-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice. J Neuroinflammation (2014) 0.87
PAR2-mediated upregulation of BDNF contributes to central sensitization in bone cancer pain. Mol Pain (2014) 0.86
Involvement of spinal chemokine CCL2 in the hyperalgesia evoked by bone cancer in mice: a role for astroglia and microglia. Cell Mol Neurobiol (2014) 0.83
Current studies of acupuncture in cancer-induced bone pain animal models. Evid Based Complement Alternat Med (2014) 0.81
ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response. Mol Pain (2014) 0.81
Treatment of Complex Regional Pain Syndrome (CRPS) using low dose naltrexone (LDN). J Neuroimmune Pharmacol (2013) 0.81
Substance P spinal signaling induces glial activation and nociceptive sensitization after fracture. Neuroscience (2015) 0.76
Colocalization of aromatase in spinal cord astrocytes: differences in expression and relationship to mechanical and thermal hyperalgesia in murine models of a painful and a non-painful bone tumor. Neuroscience (2015) 0.76
Minocycline attenuates bone cancer pain in rats by inhibiting NF-κB in spinal astrocytes. Acta Pharmacol Sin (2016) 0.76
The Analgesic and Antineuroinflammatory Effect of Baicalein in Cancer-Induced Bone Pain. Evid Based Complement Alternat Med (2015) 0.75
Effect of the ifenprodil administered into rostral anterior cingulate cortex on pain-related aversion in rats with bone cancer pain. BMC Anesthesiol (2016) 0.75
Levo-Tetrahydropalmatine Attenuates Bone Cancer Pain by Inhibiting Microglial Cells Activation. Mediators Inflamm (2015) 0.75
The Walker 256 Breast Cancer Cell- Induced Bone Pain Model in Rats. Front Pharmacol (2016) 0.75
Downregulation of Spinal G Protein-Coupled Kinase 2 Abolished the Antiallodynic Effect of Electroacupuncture. Evid Based Complement Alternat Med (2015) 0.75
Overexpression of suppressor of cytokine signaling 3 in dorsal root ganglion attenuates cancer-induced pain in rats. Mol Pain (2017) 0.75
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain (1988) 18.17
Ethical guidelines for investigations of experimental pain in conscious animals. Pain (1983) 17.70
Toll-like receptors in the induction of the innate immune response. Nature (2000) 12.23
Efficient analysis of experimental observations. Annu Rev Pharmacol Toxicol (1980) 6.82
Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol (2000) 6.57
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol (2004) 5.15
Glial activation: a driving force for pathological pain. Trends Neurosci (2001) 3.98
Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease. Nat Med (2009) 3.87
Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4. J Immunol (2001) 3.76
The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy. Proc Natl Acad Sci U S A (2005) 3.59
Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells. J Biol Chem (2001) 3.49
Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain (2005) 3.34
Spontaneous astrocytic Ca2+ oscillations in situ drive NMDAR-mediated neuronal excitation. Nat Neurosci (2001) 3.21
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. J Biol Chem (2001) 3.16
The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia. Trends Pharmacol Sci (2009) 3.06
Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats. J Neurosci (2003) 2.87
Malignant bone pain: pathophysiology and treatment. Pain (1997) 2.75
Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4). Eur J Neurosci (2008) 2.65
Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. FASEB J (2001) 2.41
Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia. Neuroscientist (2004) 2.40
Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun (2009) 2.19
Neurochemical and cellular reorganization of the spinal cord in a murine model of bone cancer pain. J Neurosci (1999) 2.19
Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6. J Exp Med (2000) 2.16
A critical role of toll-like receptor 2 in nerve injury-induced spinal cord glial cell activation and pain hypersensitivity. J Biol Chem (2007) 2.05
"Listening" and "talking" to neurons: implications of immune activation for pain control and increasing the efficacy of opioids. Brain Res Rev (2007) 1.62
A rat model of bone cancer pain. Pain (2002) 1.61
Evidence for glutamate-mediated activation of hippocampal neurons by glial calcium waves. J Neurobiol (1995) 1.55
Implications of immune-to-brain communication for sickness and pain. Proc Natl Acad Sci U S A (1999) 1.52
Glial TLR4 receptor as new target to treat neuropathic pain: efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice. Glia (2008) 1.44
Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia. Pain (2005) 1.37
The innate immunity of the central nervous system in chronic pain: the role of Toll-like receptors. Cell Mol Life Sci (2007) 1.36
Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta. Neuroscience (2010) 1.33
Morphine analgesia suppresses tumor growth and metastasis in a mouse model of cancer pain produced by orthotopic tumor inoculation. Eur J Pharmacol (2002) 1.32
Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences. Neuroscience (2010) 1.22
Different tumors in bone each give rise to a distinct pattern of skeletal destruction, bone cancer-related pain behaviors and neurochemical changes in the central nervous system. Int J Cancer (2003) 1.15
Retracted Toll-like receptor 3 contributes to spinal glial activation and tactile allodynia after nerve injury. J Neurochem (2008) 1.14
A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells. Biochem Biophys Res Commun (2006) 1.14
Differential activation of spinal cord glial cells in murine models of neuropathic and cancer pain. Eur J Pain (2008) 1.09
Could chronic pain and spread of pain sensation be induced and maintained by glial activation? Acta Physiol (Oxf) (2006) 1.07
Down-regulation of Toll-like receptor 4 gene expression by short interfering RNA attenuates bone cancer pain in a rat model. Mol Pain (2010) 1.04
Blocking EphB1 receptor forward signaling in spinal cord relieves bone cancer pain and rescues analgesic effect of morphine treatment in rodents. Cancer Res (2011) 1.02
Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats. Neuroscience (2009) 1.02
The role of TLR2 in nerve injury-induced neuropathic pain is essentially mediated through macrophages in peripheral inflammatory response. Glia (2011) 1.01
Malignant bone pain: pathophysiology and treatments. Curr Rev Pain (2000) 1.01
Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: comparison of different mouse strains. Brain Behav Immun (2011) 0.97
Puncture of a lumbar intervertebral disc induces changes in spontaneous pain behavior: an experimental study in rats. Spine (Phila Pa 1976) (2008) 0.96
Spinal microglial expression and mechanical hypersensitivity in a postoperative pain model: comparison with a neuropathic pain model. Anesthesiology (2009) 0.95
Disruption of glial function enhances electroacupuncture analgesia in arthritic rats. Exp Neurol (2006) 0.92
Tibia tumor-induced cancer pain involves spinal p38 mitogen-activated protein kinase activation via TLR4-dependent mechanisms. Brain Res (2010) 0.92
Toll-like receptors in peripheral nerve injury and neuropathic pain. Curr Top Microbiol Immunol (2009) 0.88
Naloxone ameliorates retinal lesions in Ccl2/Cx3cr1 double-deficient mice via modulation of microglia. Invest Ophthalmol Vis Sci (2011) 0.87
Beta-adrenoceptor mediated surgery-induced production of pro-inflammatory cytokines in rat microglia cells. J Neuroimmunol (2010) 0.87
Electroacupuncture downregulates TLR2/4 and pro-inflammatory cytokine expression after surgical trauma stress without adrenal glands involvement. Brain Res Bull (2009) 0.82
Chromosome 7p11.2 (EGFR) variation influences glioma risk. Hum Mol Genet (2011) 1.83
Global analysis of the transcriptional response of whitefly to tomato yellow leaf curl China virus reveals the relationship of coevolved adaptations. J Virol (2011) 1.54
Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis. J Cell Biochem (2009) 1.18
Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. EMBO J (2013) 1.15
A rat model of bone cancer pain induced by intra-tibia inoculation of Walker 256 mammary gland carcinoma cells. Biochem Biophys Res Commun (2006) 1.14
Who and what should we rely on in early diagnosis of idiopathic pulmonary fibrosis? Eur Respir J (2013) 1.11
Predictive and prognostic factors for gliomas. Expert Rev Anticancer Ther (2011) 1.05
rAAV-mediated stable expression of heme oxygenase-1 in stellate cells: a new approach to attenuate liver fibrosis in rats. Hepatology (2005) 1.04
Differential Notch1 and Notch2 expression and frequent activation of Notch signaling in gastric cancers. Arch Pathol Lab Med (2011) 1.03
Regulatory effects of emodin on NF-kappaB activation and inflammatory cytokine expression in RAW 264.7 macrophages. Int J Mol Med (2005) 1.02
Diversity of secondary endosymbionts among different putative species of the whitefly Bemisia tabaci. Insect Sci (2012) 1.02
Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts. Cancer Gene Ther (2003) 1.02
Diagnostic criteria for locating acquired arteriovenous fistulas with color Doppler sonography. J Clin Ultrasound (2002) 1.00
Transcriptomic analysis of the salivary glands of an invasive whitefly. PLoS One (2012) 0.99
Additive anti-hyperalgesia of electroacupuncture and intrathecal antisense oligodeoxynucleotide to interleukin-1 receptor type I on carrageenan-induced inflammatory pain in rats. Brain Res Bull (2008) 0.97
Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and -independent antitumor effects. Cancer Gene Ther (2003) 0.97
Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects. Diabetes (2003) 0.97
c-Myc downregulation: a critical molecular event in resveratrol-induced cell cycle arrest and apoptosis of human medulloblastoma cells. J Neurooncol (2006) 0.94
Bifunctional N-acyl-aminophosphine-catalyzed asymmetric [4+2] cycloadditions of allenoates and imines. Chemistry (2011) 0.94
Resveratrol promotes differentiation and induces Fas-independent apoptosis of human medulloblastoma cells. Neurosci Lett (2003) 0.94
The characteristics and expression profiles of the mitochondrial genome for the Mediterranean species of the Bemisia tabaci complex. BMC Genomics (2013) 0.93
Separate cis-trans pathways post-transcriptionally regulate murine CD154 (CD40 ligand) expression: a novel function for CA repeats in the 3'-untranslated region. J Biol Chem (2008) 0.93
Clomipramine treatment reversed the glial pathology in a chronic unpredictable stress-induced rat model of depression. Eur Neuropsychopharmacol (2009) 0.92
Differential expression patterns of hyaluronan receptors CD44 and RHAMM in transitional cell carcinomas of urinary bladder. Oncol Rep (2002) 0.92
Diagnostic value of anti-cyclic citrullinated peptide antibodies in northern Chinese Han patients with rheumatoid arthritis and its correlation with disease activity. Clin Rheumatol (2010) 0.90
Changes of expression of glial cell line-derived neurotrophic factor and its receptor in dorsal root ganglions and spinal dorsal horn during electroacupuncture treatment in neuropathic pain rats. Neurosci Lett (2005) 0.90
Glia atrophy in the hippocampus of chronic unpredictable stress-induced depression model rats is reversed by electroacupuncture treatment. J Affect Disord (2011) 0.90
Study of the cost-benefit analysis of electronic medical record systems in general hospital in China. J Med Syst (2012) 0.88
Activation of c-jun N-terminal kinase in spinal cord contributes to breast cancer induced bone pain in rats. Mol Brain (2012) 0.88
Characterization of a newly discovered symbiont of the whitefly Bemisia tabaci (Hemiptera: Aleyrodidae). Appl Environ Microbiol (2012) 0.88
Involvement of spinal neurotrophin-3 in electroacupuncture analgesia and inhibition of spinal glial activation in rat model of monoarthritis. J Pain (2011) 0.87
Beta-adrenoceptor mediated surgery-induced production of pro-inflammatory cytokines in rat microglia cells. J Neuroimmunol (2010) 0.87
Differential caspase-3 expression in noncancerous, premalignant and cancer tissues of stomach and its clinical implication. Cancer Detect Prev (2006) 0.87
Research progress on interleukin-33 and its roles in the central nervous system. Neurosci Bull (2011) 0.87
Chronic clomipramine treatment restores hippocampal expression of glial cell line-derived neurotrophic factor in a rat model of depression. J Affect Disord (2012) 0.87
Differential signature of fecal microRNAs in patients with pancreatic cancer. Mol Med Rep (2012) 0.87
Antimicrobial peptaibols from Trichoderma pseudokoningii induce programmed cell death in plant fungal pathogens. Microbiology (2011) 0.86
2-(4-Methoxy-phen-yl)-1H-indene. Acta Crystallogr Sect E Struct Rep Online (2008) 0.86
Changes in expression of nociceptin/orphanin FQ and its receptor in spinal dorsal horn during electroacupuncture treatment for peripheral inflammatory pain in rats. Peptides (2007) 0.85
Overexpression of S-adenosyl-L-methionine synthetase increased tomato tolerance to alkali stress through polyamine metabolism. Plant Biotechnol J (2014) 0.85
Lipoxins and aspirin-triggered lipoxin alleviate bone cancer pain in association with suppressing expression of spinal proinflammatory cytokines. J Neuroinflammation (2012) 0.85
Expression and functional characterisation of a soluble form of Tomato yellow leaf curl virus coat protein. Pest Manag Sci (2014) 0.85
Involvement of EphB1 receptor/ephrinB1 ligand in bone cancer pain. Neurosci Lett (2011) 0.85
Prognostic markers in gliomas. Future Oncol (2010) 0.85
Electroacupuncture combined with clomipramine enhances antidepressant effect in rodents. Neurosci Lett (2007) 0.85
Astrocyte-conditioned medium protecting hippocampal neurons in primary cultures against corticosterone-induced damages via PI3-K/Akt signal pathway. Brain Res (2006) 0.85
[Effects of intracerebroventricular injection of delta-opioid receptor agonist TAN-67 or antagonist naltrindole on acute cerebral ischemia in rat]. Sheng Li Xue Bao (2008) 0.85
Stage-dependent anti-allodynic effects of intrathecal Toll-like receptor 4 antagonists in a rat model of cancer induced bone pain. J Physiol Sci (2013) 0.85
Ascaris suum enolase is a potential vaccine candidate against ascariasis. Vaccine (2012) 0.84
Nuclear translocations of beta-catenin and TCF4 in gastric cancers correlate with lymph node metastasis but probably not with CD44 expression. Hum Pathol (2005) 0.84
Expression of 5-HT1A receptor mRNA in rat lumbar spinal dorsal horn neurons after peripheral inflammation. Pain (2002) 0.84
Draft genome sequence of "Candidatus Hamiltonella defensa," an endosymbiont of the whitefly Bemisia tabaci. J Bacteriol (2012) 0.84
Stage-dependent analgesia of electro-acupuncture in a mouse model of cutaneous cancer pain. Eur J Pain (2005) 0.83
Prognostic Value of Coronary Artery Stenoses, Markis Class, and Ectasia Ratio in Patients with Coronary Artery Ectasia. Cardiology (2015) 0.83
Linking inflammation to acute rejection in small-for-size liver allografts: the potential role of early macrophage activation. Am J Transplant (2004) 0.83
Molecular characterization and oxidative stress response of an intracellular Cu/Zn superoxide dismutase (CuZnSOD) of the whitefly, Bemisia tabaci. Arch Insect Biochem Physiol (2011) 0.83
T-cell-dependent antitumor effects produced by CD40 ligand expressed on mouse lung carcinoma cells are linked with the maturation of dendritic cells and secretion of a variety of cytokines. Cancer Gene Ther (2003) 0.83
Comparative genomics provide insights into evolution of trichoderma nutrition style. Genome Biol Evol (2014) 0.82
Cloning, expression and characterization of mitochondrial manganese superoxide dismutase from the Whitefly, Bemisia tabaci. Int J Mol Sci (2013) 0.82
Electroacupuncture downregulates TLR2/4 and pro-inflammatory cytokine expression after surgical trauma stress without adrenal glands involvement. Brain Res Bull (2009) 0.82
Involvement of serotonin 2A receptors in the analgesic effect of tramadol in mono-arthritic rats. Brain Res (2008) 0.82
Analysis of whitefly transcriptional responses to Beauveria bassiana infection reveals new insights into insect-fungus interactions. PLoS One (2013) 0.82
Combination of nucleic acid and protein isolation with tissue array construction: using defined histologic regions in single frozen tissue blocks for multiple research purposes. Int J Mol Med (2003) 0.82
Lipopolysaccharide-induced protein kinase D activation mediated by interleukin-1beta and protein kinase C. Brain Res (2007) 0.82
Synergistic anti-hyperalgesia of electroacupuncture and low dose of celecoxib in monoarthritic rats: involvement of the cyclooxygenase activity in the spinal cord. Brain Res Bull (2008) 0.82
Analysis of the transcriptional differences between indigenous and invasive whiteflies reveals possible mechanisms of whitefly invasion. PLoS One (2013) 0.82
Dietary variability in the western black crested gibbon (Nomascus concolor) inhabiting an isolated and disturbed forest fragment in Southern Yunnan, China. Am J Primatol (2013) 0.81
A rat model of bone inflammation-induced pain by intra-tibial complete Freund's adjuvant injection. Neurosci Lett (2010) 0.81
Selection of endogenous reference genes for gene expression analysis in the Mediterranean species of the Bemisia tabaci (Hemiptera: Aleyrodidae) complex. J Econ Entomol (2013) 0.81