Published in Clin Epigenetics on April 10, 2011
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Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes. Mol Cell Biol (2001) 2.88
LINE-1 hypomethylation is inversely associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. Int J Cancer (2008) 2.87
A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers. Gastroenterology (2009) 2.56
Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer. PLoS Genet (2010) 2.27
Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum (1990) 2.27
Precision of pyrosequencing assay to measure LINE-1 methylation in colon cancer, normal colonic mucosa, and peripheral blood cells. J Mol Diagn (2010) 2.15
Implications of LINE1 methylation for bladder cancer risk in women. Clin Cancer Res (2010) 2.10
DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity. Cancer Res (2008) 2.08
DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage. Int J Cancer (2007) 1.97
Hypermethylation of CpG island loci and hypomethylation of LINE-1 and Alu repeats in prostate adenocarcinoma and their relationship to clinicopathological features. J Pathol (2007) 1.96
Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans. Genome Res (2010) 1.94
Hypomethylation of retrotransposable elements correlates with genomic instability in non-small cell lung cancer. Int J Cancer (2009) 1.94
Retracted Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene (2005) 1.91
DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas. Br J Cancer (1999) 1.86
The relationship between global methylation level, loss of heterozygosity, and microsatellite instability in sporadic colorectal cancer. Clin Cancer Res (2005) 1.85
Hypomethylation of LINE1 retrotransposon in human hepatocellular carcinomas, but not in surrounding liver cirrhosis. Jpn J Clin Oncol (2000) 1.84
Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription. Oncogene (2010) 1.72
Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue. Int J Colorectal Dis (2003) 1.69
Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences. Physiol Genomics (2010) 1.67
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Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors. Genome Res (2011) 1.60
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DNA methylation predicts recurrence from resected stage III proximal colon cancer. Cancer (2010) 1.55
Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors. Mol Cancer (2010) 1.50
LINE-1 hypomethylation level as a potential prognostic factor for epithelial ovarian cancer. Int J Gynecol Cancer (2007) 1.50
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Aberrant DNA methylation in hereditary nonpolyposis colorectal cancer without mismatch repair deficiency. Gastroenterology (2010) 1.46
Aberrant promoter hypermethylation and genomic hypomethylation in tumor, adjacent normal tissues and blood from breast cancer patients. Anticancer Res (2010) 1.46
Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression. Gut (2010) 1.44
Coordinate hypermethylation at specific genes in prostate carcinoma precedes LINE-1 hypomethylation. Br J Cancer (2004) 1.41
High frequency of alterations in DNA methylation in adenocarcinoma of the prostate. Prostate (1999) 1.40
Genome-wide tracking of unmethylated DNA Alu repeats in normal and cancer cells. Nucleic Acids Res (2007) 1.38
Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage. Clin Cancer Res (2011) 1.38
Serum LINE-1 hypomethylation as a potential prognostic marker for hepatocellular carcinoma. Clin Chim Acta (2007) 1.38
LINE-1 methylation patterns of different loci in normal and cancerous cells. Nucleic Acids Res (2008) 1.35
CpG island methylation profiling in human melanoma cell lines. Melanoma Res (2009) 1.35
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DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. Clin Cancer Res (2009) 1.33
Intertumor and intratumor NY-ESO-1 expression heterogeneity is associated with promoter-specific and global DNA methylation status in ovarian cancer. Clin Cancer Res (2008) 1.32
Prognostic implications of and relationship between CpG island hypermethylation and repetitive DNA hypomethylation in hepatocellular carcinoma. Clin Cancer Res (2009) 1.31
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Genomewide DNA hypomethylation is associated with alterations on chromosome 8 in prostate carcinoma. Genes Chromosomes Cancer (2002) 1.28
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Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer. Int J Cancer (2006) 1.23
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Differential repetitive DNA methylation in multiple myeloma molecular subgroups. Carcinogenesis (2009) 1.18
DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage. BMC Med Genomics (2008) 1.17
LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors. Epigenetics (2009) 1.17
Repetitive DNA hypomethylation in the advanced phase of chronic myeloid leukemia. Leuk Res (2007) 1.15
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A novel correlation between LINE-1 hypomethylation and the malignancy of gastrointestinal stromal tumors. Clin Cancer Res (2010) 1.14
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Specific hypermethylation of LINE-1 elements during abnormal overgrowth and differentiation of human placenta. Oncogene (2006) 1.11
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Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia. Epigenetics (2011) 1.05
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Genome-wide analysis of DNA methylation status of CpG islands in embryoid bodies, teratomas, and fetuses. Biochem Biophys Res Commun (2003) 1.03
Comparative analysis of promoter methylation and gene expression endpoints between tumorous and non-tumorous tissues from HCV-positive patients with hepatocellular carcinoma. Mutat Res (2010) 1.03
Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis. Oncogene (2004) 3.50
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Hypomethylation of intragenic LINE-1 represses transcription in cancer cells through AGO2. PLoS One (2011) 1.18
Global gene expression profile of nasopharyngeal carcinoma by laser capture microdissection and complementary DNA microarrays. Clin Cancer Res (2004) 1.17
Replication independent DNA double-strand break retention may prevent genomic instability. Mol Cancer (2010) 1.09
Hypomethylation of LINE-1 but not Alu in lymphocyte subsets of systemic lupus erythematosus patients. Clin Chim Acta (2011) 1.07
Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer. BMC Cancer (2006) 1.04
Demographic changes and marker properties affect detection of human population differentiation. BMC Genet (2007) 1.00
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Line-1 hypomethylation in multistage carcinogenesis of the uterine cervix. Asian Pac J Cancer Prev (2007) 0.99
LINE-1 methylation in the peripheral blood mononuclear cells of cancer patients. Clin Chim Acta (2012) 0.99
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Epstein-Barr virus infection-associated smooth-muscle tumors in patients with AIDS. Clin Infect Dis (2005) 0.94
Long interspersed nuclear element-1 hypomethylation and oxidative stress: correlation and bladder cancer diagnostic potential. PLoS One (2012) 0.94
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Improved measurement of LINE-1 sequence methylation for cancer detection. Clin Chim Acta (2010) 0.93
Inter-rater reliability and concurrent validity of DSM-IV opioid dependence in a Hmong isolate using the Thai version of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA). Addict Behav (2010) 0.93
Patterns and possible roles of LINE-1 methylation changes in smoke-exposed epithelia. PLoS One (2012) 0.92
SHP-1 promoter 2 methylation in normal epithelial tissues and demethylation in psoriasis. J Mol Med (Berl) (2005) 0.91
Identification of population substructure among Jews using STR markers and dependence on reference populations included. BMC Genet (2010) 0.91
A gene conversion hotspot in the human growth hormone (GH1) gene promoter. Hum Mutat (2009) 0.90
Detection of LINE-1s hypomethylation in oral rinses of oral squamous cell carcinoma patients. Oral Oncol (2008) 0.90
DNA methylation of human endogenous retrovirus in systemic lupus erythematosus. J Hum Genet (2013) 0.90
Promoter hypermethylation of CCNA1, RARRES1, and HRASLS3 in nasopharyngeal carcinoma. Oral Oncol (2007) 0.88
Hypomethylation of Alu elements in post-menopausal women with osteoporosis. PLoS One (2013) 0.88
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The impact of non-tumor-derived circulating nucleic acids implicates the prognosis of non-small cell lung cancer. J Cancer Res Clin Oncol (2012) 0.85
Differences in LINE-1 methylation between endometriotic ovarian cyst and endometriosis-associated ovarian cancer. Int J Gynecol Cancer (2014) 0.85
LINE-1 insertion dimorphisms identification by PCR. Biotechniques (2004) 0.85
HERV-K hypomethylation in ovarian clear cell carcinoma is associated with a poor prognosis and platinum resistance. Int J Gynecol Cancer (2011) 0.83
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Oxidative stress induces hypomethylation of LINE-1 and hypermethylation of the RUNX3 promoter in a bladder cancer cell line. Asian Pac J Cancer Prev (2013) 0.82
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Clinical features of methamphetamine-induced paranoia and preliminary genetic association with DBH-1021C→T in a Thai treatment cohort. Addiction (2014) 0.80
LINE-1 and Alu hypomethylation in mucoepidermoid carcinoma. BMC Clin Pathol (2013) 0.80
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Parakeratosis in skin is associated with loss of inhibitor of differentiation 4 via promoter methylation. Hum Pathol (2011) 0.80
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LINE-1 and Alu methylation patterns in lymph node metastases of head and neck cancers. Asian Pac J Cancer Prev (2012) 0.79
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XRCC1 gene polymorphisms and risk of ameloblastoma. Arch Oral Biol (2012) 0.79
CCNA1 promoter methylation: a potential marker for grading Papanicolaou smear cervical squamous intraepithelial lesions. Asian Pac J Cancer Prev (2014) 0.77
Alu methylation in serum from patients with nasopharyngeal carcinoma. Asian Pac J Cancer Prev (2014) 0.77
Targeted therapies for rare gynaecological cancers. Lancet Oncol (2010) 0.77
Upstream mononucleotide A-repeats play a cis-regulatory role in mammals through the DICER1 and Ago proteins. Nucleic Acids Res (2013) 0.77
Candidate cancer-targeting agents identified by expression-profiling arrays. Onco Targets Ther (2013) 0.76
Alu hypomethylation in smoke-exposed epithelia and oral squamous carcinoma. Asian Pac J Cancer Prev (2013) 0.76
Codon72 polymorphism in the p53 tumor suppressor gene in oral lichen planus lesions in a Thai population. Asian Pac J Cancer Prev (2010) 0.76
Association of interferon-gamma gene polymorphisms with susceptibility to oral lichen planus in the Thai population. Arch Oral Biol (2011) 0.76
The role of SHP-1 promoter 2 hypermethylation detection of lymph node micrometastasis in resectable stage I non-small cell lung cancer as a prognostic marker of disease recurrence. Int J Clin Oncol (2013) 0.76
Identification of Pancreatic Cancer in Biliary Obstruction Patients by FRY Site-specific Methylation. Asian Pac J Cancer Prev (2016) 0.75
Alterations in the LINE-1 methylation pattern in patients with lichen simplex chronicus. Asian Pac J Allergy Immunol (2013) 0.75
Future cancer management with stem cell knowledge and technology. J Med Assoc Thai (2006) 0.75
Sex Steroids Regulate Expression of Genes Containing Long Interspersed Elements-1s in Breast Cancer Cells. Asian Pac J Cancer Prev (2016) 0.75
Epithelial-Specific SHP1-P2 Methylation - a Novel Universal Tumor Marker for Detection of Colorectal Cancer Lymph Node Metastasis. Asian Pac J Cancer Prev (2016) 0.75
Survey of human papillomavirus infection in cervical intraepithelial neoplasia in Thai women. J Med Assoc Thai (2002) 0.75
P53 polymorphism at codon 72 is associated with keratocystic odontogenic tumors in the Thai population. Asian Pac J Cancer Prev (2015) 0.75