Published in Genomics on June 15, 2012
Epigenetic regulation of the lncRNA MEG3 and its target c-MET in pancreatic neuroendocrine tumors. Mol Endocrinol (2015) 1.01
Kagami-Ogata syndrome: a clinically recognizable upd(14)pat and related disorder affecting the chromosome 14q32.2 imprinted region. J Hum Genet (2015) 0.88
Long noncoding RNAs in imprinting and X chromosome inactivation. Biomolecules (2014) 0.81
Regulation of Mammalian Gene Dosage by Long Noncoding RNAs. Biomolecules (2013) 0.76
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature (2007) 65.18
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature (1998) 18.36
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene. Nature (2000) 14.91
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet (1998) 13.27
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus. Nature (2000) 12.97
Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol Cell Biol (1998) 7.61
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev (1999) 7.58
Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Dev Cell (2003) 7.11
CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. Genes Dev (2006) 6.32
Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev (1998) 6.29
The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev (2004) 6.20
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci U S A (2006) 5.95
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nat Genet (1999) 5.61
Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Nat Genet (1999) 5.58
Imprinted expression of the Igf2r gene depends on an intronic CpG island. Nature (1997) 5.08
The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation. Curr Biol (2005) 4.52
Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12. Nat Genet (2003) 4.25
Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals. Nature (1998) 3.93
Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat Genet (2002) 3.88
Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes. Nat Genet (2004) 3.33
Genome imprinting regulated by the mouse Polycomb group protein Eed. Nat Genet (2003) 2.97
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor. Genes Dev (2001) 2.91
The Dlk1 and Gtl2 genes are linked and reciprocally imprinted. Genes Dev (2000) 2.68
CTCF, a candidate trans-acting factor for X-inactivation choice. Science (2001) 2.59
Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function. Curr Biol (2000) 2.46
A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins. Nat Genet (1997) 2.43
Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes. EMBO J (2002) 2.40
Epigenetic analysis of the Dlk1-Gtl2 imprinted domain on mouse chromosome 12: implications for imprinting control from comparison with Igf2-H19. Hum Mol Genet (2002) 2.33
Delta-like and gtl2 are reciprocally expressed, differentially methylated linked imprinted genes on mouse chromosome 12. Curr Biol (2000) 2.19
Analysis of candidate imprinted genes linked to Dlk1-Gtl2 using a congenic mouse line. Mamm Genome (2002) 2.11
The polycomb group protein EED interacts with YY1, and both proteins induce neural tissue in Xenopus embryos. Mol Cell Biol (2001) 1.98
dlk, a putative mammalian homeotic gene differentially expressed in small cell lung carcinoma and neuroendocrine tumor cell line. J Biol Chem (1993) 1.90
Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q. Genes Cells (2000) 1.90
The mouse Gtl2 gene is differentially expressed during embryonic development, encodes multiple alternatively spliced transcripts, and may act as an RNA. Dev Dyn (1998) 1.74
Deletion of Gtl2, imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice. Hum Mol Genet (2009) 1.72
Trichostatin A causes selective loss of DNA methylation in Neurospora. Proc Natl Acad Sci U S A (1998) 1.66
Epigenetic mechanism of rRNA gene silencing: temporal order of NoRC-mediated histone modification, chromatin remodeling, and DNA methylation. Mol Cell Biol (2005) 1.66
Multiple nucleosome positioning sites regulate the CTCF-mediated insulator function of the H19 imprinting control region. Mol Cell Biol (2002) 1.49
Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker. Mol Cell Biol (2005) 1.43
Loss of imprinting at the Dlk1-Gtl2 locus caused by insertional mutagenesis in the Gtl2 5' region. BMC Genet (2006) 1.37
Gtl2lacZ, an insertional mutation on mouse chromosome 12 with parental origin-dependent phenotype. Mamm Genome (1996) 1.34
Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain. Genes Dev (2006) 1.27
Allele-specific histone modifications regulate expression of the Dlk1-Gtl2 imprinted domain. Genomics (2006) 1.27
Maintenance of paternal methylation and repression of the imprinted H19 gene requires MBD3. PLoS Genet (2007) 1.24
Allele-specific methylation of a functional CTCF binding site upstream of MEG3 in the human imprinted domain of 14q32. Chromosome Res (2005) 1.20
The transcriptional status but not the imprinting control region determines allele-specific histone modifications at the imprinted H19 locus. Mol Cell Biol (2007) 1.07
Allele-specific deposition of macroH2A1 in imprinting control regions. Hum Mol Genet (2006) 1.06
Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res (2006) 1.03
Allele-specific H3K79 Di- versus trimethylation distinguishes opposite parental alleles at imprinted regions. Mol Cell Biol (2010) 1.01
Nonallelic transcriptional roles of CTCF and cohesins at imprinted loci. Mol Cell Biol (2011) 0.96
Analysis of candidate imprinted genes linked to Dlk1-Gtl2 using a congenic mouse line. Mamm Genome (2002) 2.11
Loss of imprinting at the Dlk1-Gtl2 locus caused by insertional mutagenesis in the Gtl2 5' region. BMC Genet (2006) 1.37
Dlk1 is necessary for proper skeletal muscle development and regeneration. PLoS One (2010) 1.28
Allele-specific histone modifications regulate expression of the Dlk1-Gtl2 imprinted domain. Genomics (2006) 1.27
Dlk1 expression marks developing endothelium and sites of branching morphogenesis in the mouse embryo and placenta. Dev Dyn (2006) 1.14
A 178-kb BAC transgene imprints the mouse Gtl2 gene and localizes tissue-specific regulatory elements. Genomics (2004) 0.93
Conditional deletions refine the embryonic requirement for Dlk1. Mech Dev (2012) 0.93
Coordinated diurnal regulation of genes from the Dlk1-Dio3 imprinted domain: implications for regulation of clusters of non-paralogous genes. Hum Mol Genet (2007) 0.86
Oxytocin selectively increases ERalpha mRNA in the neonatal hypothalamus and hippocampus of female prairie voles. Neuropeptides (2006) 0.81
Localizing transcriptional regulatory elements at the mouse Dlk1 locus. PLoS One (2012) 0.79
Novel imprinted transcripts from the Dlk1-Gtl2 intergenic region, Mico1 and Mico1os, show circadian oscillations. Epigenetics (2008) 0.79
Disruption of the mouse Jhy gene causes abnormal ciliary microtubule patterning and juvenile hydrocephalus. Dev Biol (2013) 0.78
Expression of a modified H19 RNA does not cause embryonic lethality in mice. Mamm Genome (2006) 0.76
Imprinting analysis in the Acrodysplasia region of mouse chromosome 12. Biosci Rep (2009) 0.75