Published in Mol Cell Biol on April 01, 2005
Multimegabase silencing in nucleolar dominance involves siRNA-directed DNA methylation and specific methylcytosine-binding proteins. Mol Cell (2008) 1.94
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol (2010) 1.91
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep (2008) 1.64
UBF levels determine the number of active ribosomal RNA genes in mammals. J Cell Biol (2008) 1.57
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A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription. PLoS Genet (2017) 0.75
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A transient histone hyperacetylation signal marks nucleosomes for remodeling at the PHO8 promoter in vivo. Mol Cell (2001) 1.70
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Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin. Mol Cell Biol (2004) 1.15
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The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription. EMBO J (2002) 2.36
The nucleolus as a stress sensor: JNK2 inactivates the transcription factor TIF-IA and down-regulates rRNA synthesis. Genes Dev (2005) 2.13
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TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation. Mol Cell (2009) 1.97
Activation of RNA polymerase I transcription by cockayne syndrome group B protein and histone methyltransferase G9a. Mol Cell (2007) 1.96
CSB is a component of RNA pol I transcription. Mol Cell (2002) 1.93
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol (2010) 1.91
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The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing. Curr Biol (2005) 1.75
The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus. EMBO Rep (2008) 1.64
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The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres. EMBO Rep (2013) 1.55
Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter. EMBO Rep (2002) 1.48
Modulation of RNA polymerase assembly dynamics in transcriptional regulation. Mol Cell (2008) 1.47
TFIIH plays an essential role in RNA polymerase I transcription. Cell (2002) 1.43
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells. Nucleic Acids Res (2007) 1.42
Repression of RNA polymerase I upon stress is caused by inhibition of RNA-dependent deacetylation of PAF53 by SIRT7. Mol Cell (2013) 1.41
The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats. EMBO J (2010) 1.40
AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply. Proc Natl Acad Sci U S A (2009) 1.40
NoRC-dependent nucleosome positioning silences rRNA genes. EMBO J (2006) 1.39
NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells (2013) 1.35
The chromatin remodeling complex NoRC controls replication timing of rRNA genes. EMBO J (2004) 1.34
Reversible acetylation of the chromatin remodelling complex NoRC is required for non-coding RNA-dependent silencing. Nat Cell Biol (2009) 1.30
Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling. J Neurosci (2011) 1.20
The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivo. Nucleic Acids Res (2004) 1.16
Recruitment of the nucleolar remodeling complex NoRC establishes ribosomal DNA silencing in chromatin. Mol Cell Biol (2004) 1.15
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The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions. Proc Natl Acad Sci U S A (2012) 1.13
Activation of an endogenous suicide response after perturbation of rRNA synthesis leads to neurodegeneration in mice. J Neurosci (2008) 1.12
Phosphorylation by casein kinase 2 facilitates rRNA gene transcription by promoting dissociation of TIF-IA from elongating RNA polymerase I. Mol Cell Biol (2008) 1.10
Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans. EMBO Rep (2009) 1.05
Human Cdc14B promotes progression through mitosis by dephosphorylating Cdc25 and regulating Cdk1/cyclin B activity. PLoS One (2011) 1.01
Acetylation of UBF changes during the cell cycle and regulates the interaction of UBF with RNA polymerase I. Nucleic Acids Res (2006) 0.94
Proteasomal ATPases are associated with rDNA: the ubiquitin proteasome system plays a direct role in RNA polymerase I transcription. Biochim Biophys Acta (2008) 0.94
A model for the topology of active ribosomal RNA genes. EMBO Rep (2011) 0.93
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Linking rDNA transcription to the cellular energy supply. Cell Cycle (2010) 0.90
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Development of a species-specific RNA polymerase I-based shRNA expression vector. Nucleic Acids Res (2006) 0.86
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DNA sequence encoded repression of rRNA gene transcription in chromatin. Nucleic Acids Res (2010) 0.84
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