Published in Sci Transl Med on July 04, 2012
Inertial focusing for tumor antigen-dependent and -independent sorting of rare circulating tumor cells. Sci Transl Med (2013) 4.74
Microfluidic, marker-free isolation of circulating tumor cells from blood samples. Nat Protoc (2014) 1.80
Single-cell magnetic imaging using a quantum diamond microscope. Nat Methods (2015) 1.53
Rare cell isolation and analysis in microfluidics. Lab Chip (2014) 1.42
A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria. Nat Nanotechnol (2013) 1.35
Probing circulating tumor cells in microfluidics. Lab Chip (2013) 1.34
Advancing the speed, sensitivity and accuracy of biomolecular detection using multi-length-scale engineering. Nat Nanotechnol (2014) 1.18
Circulating tumor cells: advances in isolation and analysis, and challenges for clinical applications. Pharmacol Ther (2013) 1.15
Circulating tumor cells: getting more from less. Sci Transl Med (2012) 1.07
Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips. Lab Chip (2014) 1.07
Circulating tumor cells and DNA as liquid biopsies. Genome Med (2013) 1.06
Multivalent DNA nanospheres for enhanced capture of cancer cells in microfluidic devices. ACS Nano (2013) 1.05
Magnetic sensing technology for molecular analyses. Lab Chip (2014) 1.01
Emerging role of nanomaterials in circulating tumor cell isolation and analysis. ACS Nano (2014) 1.00
μHall chip for sensitive detection of bacteria. Adv Healthc Mater (2013) 0.96
Micro total analysis systems: fundamental advances and applications in the laboratory, clinic, and field. Anal Chem (2012) 0.92
Detection and isolation of circulating exosomes and microvesicles for cancer monitoring and diagnostics using micro-/nano-based devices. Analyst (2016) 0.89
Characterizing asthma from a drop of blood using neutrophil chemotaxis. Proc Natl Acad Sci U S A (2014) 0.89
Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cells. J Am Chem Soc (2012) 0.88
Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance. Nanomedicine (2013) 0.86
Track-etched magnetic micropores for immunomagnetic isolation of pathogens. Adv Healthc Mater (2014) 0.85
High performance wash-free magnetic bioassays through microfluidically enhanced particle specificity. Sci Rep (2015) 0.85
New generation of ensemble-decision aliquot ranking based on simplified microfluidic components for large-capacity trapping of circulating tumor cells. Anal Chem (2013) 0.83
Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and a miniaturized micro-NMR system. Nanomedicine (2013) 0.82
Enhancing reactivity for bioorthogonal pretargeting by unmasking antibody-conjugated trans-cyclooctenes. Bioconjug Chem (2015) 0.82
Towards the Biological Understanding of CTC: Capture Technologies, Definitions and Potential to Create Metastasis. Cancers (Basel) (2013) 0.82
Biosensors for the detection of circulating tumour cells. Sensors (Basel) (2014) 0.81
Laser micromachined hybrid open/paper microfluidic chips. Biomicrofluidics (2013) 0.81
Dawn of advanced molecular medicine: nanotechnological advancements in cancer imaging and therapy. Crit Rev Oncog (2014) 0.81
Paired diagnostic and pharmacodynamic analysis of rare non-small cell lung cancer cells enabled by the VerIFAST platform. Lab Chip (2014) 0.81
Prognostic relevance of minimal residual disease in colorectal cancer. World J Gastroenterol (2014) 0.81
Dielectrophoretic capture and genetic analysis of single neuroblastoma tumor cells. Front Oncol (2014) 0.81
Current Understanding of Circulating Tumor Cells - Potential Value in Malignancies of the Central Nervous System. Front Neurol (2015) 0.80
A multi-scale PDMS fabrication strategy to bridge the size mismatch between integrated circuits and microfluidics. Lab Chip (2014) 0.80
Microchip-based detection of magnetically labeled cancer biomarkers. Adv Drug Deliv Rev (2013) 0.80
Nanotechnology for enrichment and detection of circulating tumor cells. Nanomedicine (Lond) (2015) 0.80
Detection methods of circulating tumor cells. J Thorac Dis (2012) 0.80
Magnetic fingerprints of rolling cells for quantitative flow cytometry in whole blood. Sci Rep (2016) 0.80
Microfluidic device for mechanical dissociation of cancer cell aggregates into single cells. Lab Chip (2015) 0.80
Applications of microfluidics and microchip electrophoresis for potential clinical biomarker analysis. Anal Bioanal Chem (2015) 0.79
Screening and Molecular Analysis of Single Circulating Tumor Cells Using Micromagnet Array. Sci Rep (2015) 0.79
Recent Advances in the Analysis of Single Cells. Anal Chem (2016) 0.78
Detection of circulating tumor cells. Scientifica (Cairo) (2014) 0.78
Diagnostic technologies for circulating tumour cells and exosomes. Biosci Rep (2015) 0.77
Rational Design of Materials Interface for Efficient Capture of Circulating Tumor Cells. Adv Sci (Weinh) (2015) 0.77
Supervised discriminant analysis for droplet micro-magnetofluidics. Microfluid Nanofluidics (2015) 0.77
Point-of-care rare cell cancer diagnostics. Methods Mol Biol (2015) 0.77
Magnetic ligation method for quantitative detection of microRNAs. Adv Healthc Mater (2014) 0.76
Single cell analysis of cancer cells using an improved RT-MLPA method has potential for cancer diagnosis and monitoring. Sci Rep (2015) 0.75
Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood. Nanomedicine (2016) 0.75
Tumor-selective replication herpes simplex virus-based technology significantly improves clinical detection and prognostication of viable circulating tumor cells. Oncotarget (2016) 0.75
Circulating Tumor Cells in Metastatic Breast Cancer: A Prognostic and Predictive Marker. J Patient Cent Res Rev (2014) 0.75
Magnetic Nickel iron Electroformed Trap (MagNET): a master/replica fabrication strategy for ultra-high throughput (>100 mL h(-1)) immunomagnetic sorting. Lab Chip (2016) 0.75
A magnetic micropore chip for rapid (<1 hour) unbiased circulating tumor cell isolation and in situ RNA analysis. Lab Chip (2017) 0.75
Circulating Tumor DNA as Biomarkers for Cancer Detection. Genomics Proteomics Bioinformatics (2017) 0.75
Isolation of rare circulating tumour cells in cancer patients by microchip technology. Nature (2007) 19.33
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science (2011) 15.45
A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature (2003) 7.69
Surface plasmon resonance sensors for detection of chemical and biological species. Chem Rev (2008) 5.59
Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood. Nat Biotechnol (2008) 4.40
Chip-NMR biosensor for detection and molecular analysis of cells. Nat Med (2008) 4.29
Matrix-insensitive protein assays push the limits of biosensors in medicine. Nat Med (2009) 3.58
Rapid detection and profiling of cancer cells in fine-needle aspirates. Proc Natl Acad Sci U S A (2009) 2.75
Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection. Nat Nanotechnol (2010) 2.49
Quantification of protein interactions and solution transport using high-density GMR sensor arrays. Nat Nanotechnol (2011) 2.26
Multitarget magnetic activated cell sorter. Proc Natl Acad Sci U S A (2008) 2.21
Micro-NMR for rapid molecular analysis of human tumor samples. Sci Transl Med (2011) 1.96
Holographic pixel super-resolution in portable lensless on-chip microscopy using a fiber-optic array. Lab Chip (2011) 1.92
Two simple and rugged designs for creating microfluidic sheath flow. Lab Chip (2008) 1.64
Quantifying colorimetric assays in paper-based microfluidic devices by measuring the transmission of light through paper. Anal Chem (2009) 1.61
The force acting on a superparamagnetic bead due to an applied magnetic field. Lab Chip (2007) 1.61
Antibody-based proteomics: fast-tracking molecular diagnostics in oncology. Nat Rev Cancer (2010) 1.54
Association with HSP90 inhibits Cbl-mediated down-regulation of mutant epidermal growth factor receptors. Cancer Res (2006) 1.54
Highly magnetic core-shell nanoparticles with a unique magnetization mechanism. Angew Chem Int Ed Engl (2011) 1.34
Microfluidics closes in on point-of-care assays. Nat Biotechnol (2008) 1.21
Magnetoresistive chip cytometer. Lab Chip (2011) 1.12
High speed multi-frequency impedance analysis of single particles in a microfluidic cytometer using maximum length sequences. Lab Chip (2007) 1.09
Integrated microfluidic bioprocessor for solid phase capture immunoassays. Lab Chip (2011) 1.04
Supramolecular host-guest interaction for labeling and detection of cellular biomarkers. Angew Chem Int Ed Engl (2011) 1.02
Carboxymethylated polyvinyl alcohol stabilizes doped ferrofluids for biological applications. Adv Mater (2010) 0.99
Molecular profiling and prognostic relevance of circulating tumor cells in the blood of ovarian cancer patients at primary diagnosis and after platinum-based chemotherapy. Int J Gynecol Cancer (2011) 0.98
A microfluidic microprocessor: controlling biomimetic containers and cells using hybrid integrated circuit/microfluidic chips. Lab Chip (2010) 0.91
Nanogap field-effect transistor biosensors for electrical detection of avian influenza. Small (2009) 0.89
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med (2008) 14.47
Restoration of p53 function leads to tumour regression in vivo. Nature (2007) 12.62
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med (2007) 11.51
Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science (2009) 10.47
Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett (2006) 10.12
Looking and listening to light: the evolution of whole-body photonic imaging. Nat Biotechnol (2005) 9.57
Noninvasive detection of clinically occult lymph-node metastases in prostate cancer. N Engl J Med (2003) 9.09
Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata. J Clin Invest (2007) 8.65
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell (2012) 7.36
Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. Eur Radiol (2002) 6.06
Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther (2005) 6.04
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A (2006) 5.90
Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano (2008) 5.68
Fluorescence molecular tomography resolves protease activity in vivo. Nat Med (2002) 5.53
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell (2006) 5.34
Arthritis critically dependent on innate immune system players. Immunity (2002) 5.31
Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell (2002) 5.11
The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha. Cell (2010) 5.11
Myocardial infarction accelerates atherosclerosis. Nature (2012) 4.48
Chip-NMR biosensor for detection and molecular analysis of cells. Nat Med (2008) 4.29
Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo. Circulation (2007) 4.20
Local proliferation dominates lesional macrophage accumulation in atherosclerosis. Nat Med (2013) 4.14
Magnetic relaxation switches capable of sensing molecular interactions. Nat Biotechnol (2002) 4.13
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A (2004) 4.12
Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy. Nat Med (2012) 4.11
A spatially and temporally restricted mouse model of soft tissue sarcoma. Nat Med (2007) 3.96
Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat Biotechnol (2011) 3.95
Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjug Chem (2008) 3.93
Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation. Immunity (2006) 3.92
Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis. Circulation (2007) 3.85
Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angew Chem Int Ed Engl (2009) 3.63
Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis. Circulation (2006) 3.57
Multimodality molecular imaging identifies proteolytic and osteogenic activities in early aortic valve disease. Circulation (2007) 3.51
Molecular imaging in drug discovery and development. Nat Rev Drug Discov (2003) 3.44
Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A (2006) 3.38
Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev (2008) 3.34
A secreted luciferase for ex vivo monitoring of in vivo processes. Nat Methods (2008) 3.31
Intravital imaging. Cell (2011) 3.18
Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs. Small (2007) 3.05
Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J Exp Med (2012) 2.92
Multivalent effects of RGD peptides obtained by nanoparticle display. J Med Chem (2006) 2.91
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res (2007) 2.90
Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J Am Coll Cardiol (2010) 2.90
Near-infrared fluorescence: application to in vivo molecular imaging. Curr Opin Chem Biol (2009) 2.89
An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles. Nat Mater (2006) 2.84
The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism. Cell (2012) 2.78
Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct. Circ Res (2007) 2.77
Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc Natl Acad Sci U S A (2004) 2.77
Rapid detection and profiling of cancer cells in fine-needle aspirates. Proc Natl Acad Sci U S A (2009) 2.75
Assessing the effect of surface chemistry on gold nanorod uptake, toxicity, and gene expression in mammalian cells. Small (2008) 2.74
Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. ACS Nano (2008) 2.73
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proc Natl Acad Sci U S A (2006) 2.72
Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle. Circ Res (2005) 2.67
Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice. Gastroenterology (2002) 2.64
In vivo imaging of proteolytic activity in atherosclerosis. Circulation (2002) 2.62
Molecular imaging in the clinical arena. JAMA (2005) 2.59
A submillimeter resolution fluorescence molecular imaging system for small animal imaging. Med Phys (2003) 2.58
Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg (2006) 2.58
Imaging survival and function of transplanted cardiac resident stem cells. J Am Coll Cardiol (2009) 2.58
miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells. Cancer Cell (2008) 2.57
Bioorthogonal turn-on probes for imaging small molecules inside living cells. Angew Chem Int Ed Engl (2010) 2.57
Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo. Circulation (2006) 2.56
A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation. Cancer Res (2003) 2.55
Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis. Circulation (2008) 2.52
Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection. Nat Nanotechnol (2010) 2.49
One-Pot Synthesis of New Symmetric and Asymmetric Xanthene Dyes. Tetrahedron Lett (2007) 2.49
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci U S A (2009) 2.47
Effect of tumor microenvironment modulation on the efficacy of oncolytic virus therapy. J Natl Cancer Inst (2007) 2.46
Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Circulation (2005) 2.45
Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes. Bioconjug Chem (2002) 2.45
Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions. Circulation (2011) 2.45
Origins of tumor-associated macrophages and neutrophils. Proc Natl Acad Sci U S A (2012) 2.42
PET/MRI of inflammation in myocardial infarction. J Am Coll Cardiol (2012) 2.39
Identification of the target self-antigens in reperfusion injury. J Exp Med (2006) 2.38
Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line. ACS Nano (2010) 2.36
Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. ACS Nano (2009) 2.36
Molecular imaging of cardiovascular disease. Circulation (2007) 2.33
Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice. Radiology (2007) 2.29
PepBank--a database of peptides based on sequence text mining and public peptide data sources. BMC Bioinformatics (2007) 2.27
Quantitative real-time catheter-based fluorescence molecular imaging in mice. Radiology (2007) 2.26
Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor. Circulation (2007) 2.20
Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo. Circulation (2007) 2.19
18F-4V for PET-CT imaging of VCAM-1 expression in atherosclerosis. JACC Cardiovasc Imaging (2009) 2.17
Hybrid PET-optical imaging using targeted probes. Proc Natl Acad Sci U S A (2010) 2.17
Volumetric tomography of fluorescent proteins through small animals in vivo. Proc Natl Acad Sci U S A (2005) 2.16
Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors. Arterioscler Thromb Vasc Biol (2009) 2.15
Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol (2006) 2.12
In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors. Cancer Res (2003) 2.12
Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging. Nat Immunol (2012) 2.11
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Proc Natl Acad Sci U S A (2009) 2.11
Biocompatibility, biodistribution, and drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals. Small (2010) 2.10
Biomedical applications of tetrazine cycloadditions. Acc Chem Res (2011) 2.10
Innate response activator B cells protect against microbial sepsis. Science (2012) 2.07
Arterial and aortic valve calcification abolished by elastolytic cathepsin S deficiency in chronic renal disease. Circulation (2009) 2.07
Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med (2008) 2.06
Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A (2008) 2.04
Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle. Magn Reson Med (2005) 2.03