Published in J Biol Chem on July 09, 2012
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Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis. EMBO J (2015) 1.03
AUTOPHAGY-RELATED11 plays a critical role in general autophagy- and senescence-induced mitophagy in Arabidopsis. Plant Cell (2014) 0.98
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Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy. Autophagy (2016) 0.80
PI3P binding by Atg21 organises Atg8 lipidation. EMBO J (2015) 0.79
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Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p. J Biol Chem (2010) 1.34
The ATG1/ATG13 protein kinase complex is both a regulator and a target of autophagic recycling in Arabidopsis. Plant Cell (2011) 1.26
Autophosphorylation within the Atg1 activation loop is required for both kinase activity and the induction of autophagy in Saccharomyces cerevisiae. Genetics (2010) 1.17
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Autophagy-related protein 32 acts as autophagic degron and directly initiates mitophagy. J Biol Chem (2012) 1.09
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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci (2004) 9.20
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Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion. Cell (2007) 7.11
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci (2003) 6.50
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy. J Biol Chem (2007) 6.28
Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells (2007) 6.14
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy. Dev Cell (2009) 5.85
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Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem (2002) 4.27
Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell (2005) 4.02
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Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene. Plant Physiol (2002) 3.47
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Processing of ATG8s, ubiquitin-like proteins, and their deconjugation by ATG4s are essential for plant autophagy. Plant Cell (2004) 3.17
Tor directly controls the Atg1 kinase complex to regulate autophagy. Mol Cell Biol (2009) 2.86
Atg8-family interacting motif crucial for selective autophagy. FEBS Lett (2010) 2.83
Yeast autophagosomes: de novo formation of a membrane structure. Trends Cell Biol (2002) 2.69
Autophagy is required for maintenance of amino acid levels and protein synthesis under nitrogen starvation. J Biol Chem (2005) 2.64
Assortment of phosphatidylinositol 3-kinase complexes--Atg14p directs association of complex I to the pre-autophagosomal structure in Saccharomyces cerevisiae. Mol Biol Cell (2006) 2.63
Organization of the pre-autophagosomal structure responsible for autophagosome formation. Mol Biol Cell (2008) 2.49
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Mol Cell Biol (2005) 2.44
Autophagy negatively regulates cell death by controlling NPR1-dependent salicylic acid signaling during senescence and the innate immune response in Arabidopsis. Plant Cell (2009) 2.32
The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy. EMBO J (2009) 2.25
In vivo and in vitro reconstitution of Atg8 conjugation essential for autophagy. J Biol Chem (2004) 2.21
Structure of Atg5.Atg16, a complex essential for autophagy. J Biol Chem (2006) 2.18
Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J Cell Biol (2012) 2.12
AtATG genes, homologs of yeast autophagy genes, are involved in constitutive autophagy in Arabidopsis root tip cells. Plant Cell Physiol (2006) 2.06
The crystal structure of microtubule-associated protein light chain 3, a mammalian homologue of Saccharomyces cerevisiae Atg8. Genes Cells (2004) 1.98
Autophagy in development and stress responses of plants. Autophagy (2006) 1.93
Mobilization of rubisco and stroma-localized fluorescent proteins of chloroplasts to the vacuole by an ATG gene-dependent autophagic process. Plant Physiol (2008) 1.91
Functional cooperation and separation of translocators in protein import into mitochondria, the double-membrane bounded organelles. J Cell Sci (2003) 1.90
The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function. J Biol Chem (2008) 1.89
Cis1/Atg31 is required for autophagosome formation in Saccharomyces cerevisiae. Biochem Biophys Res Commun (2007) 1.87
The early secretory pathway contributes to autophagy in yeast. Cell Struct Funct (2003) 1.83
Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae. Genes Cells (2008) 1.74
Organelle degradation during the lens and erythroid differentiation is independent of autophagy. Biochem Biophys Res Commun (2005) 1.73
Autophagy plays a role in chloroplast degradation during senescence in individually darkened leaves. Plant Physiol (2008) 1.72
Current knowledge of the pre-autophagosomal structure (PAS). FEBS Lett (2010) 1.72
Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy. EMBO Rep (2006) 1.72
Tertiary structure-function analysis reveals the pathogenic signaling potentiation mechanism of Helicobacter pylori oncogenic effector CagA. Cell Host Microbe (2012) 1.72
Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy. J Biol Chem (2005) 1.70
Identification of Tim40 that mediates protein sorting to the mitochondrial intermembrane space. J Biol Chem (2004) 1.69
Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae. Dev Cell (2002) 1.68
Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly. J Cell Biol (2004) 1.66
The crystal structure of plant ATG12 and its biological implication in autophagy. Autophagy (2005) 1.63
Starvation triggers the delivery of the endoplasmic reticulum to the vacuole via autophagy in yeast. Traffic (2005) 1.62
Ald6p is a preferred target for autophagy in yeast, Saccharomyces cerevisiae. J Biol Chem (2004) 1.60
SKD1 AAA ATPase-dependent endosomal transport is involved in autolysosome formation. Cell Struct Funct (2002) 1.58
The crystal structure of Atg3, an autophagy-related ubiquitin carrier protein (E2) enzyme that mediates Atg8 lipidation. J Biol Chem (2007) 1.55
Characterization of a novel autophagy-specific gene, ATG29. Biochem Biophys Res Commun (2005) 1.54
Crystallographic and NMR evidence for flexibility in oligosaccharyltransferases and its catalytic significance. Structure (2012) 1.52
Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis. Autophagy (2012) 1.52
Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction. PLoS One (2011) 1.51
Atg17 recruits Atg9 to organize the pre-autophagosomal structure. Genes Cells (2009) 1.50
PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans. J Clin Invest (2008) 1.45
Characterization of the Atg17-Atg29-Atg31 complex specifically required for starvation-induced autophagy in Saccharomyces cerevisiae. Biochem Biophys Res Commun (2009) 1.44
An Arabidopsis homolog of yeast ATG6/VPS30 is essential for pollen germination. Plant Physiol (2007) 1.44
In vitro reconstitution of plant Atg8 and Atg12 conjugation systems essential for autophagy. J Biol Chem (2007) 1.43
Tim23-Tim50 pair coordinates functions of translocators and motor proteins in mitochondrial protein import. J Cell Biol (2009) 1.42
Fine mapping of autophagy-related proteins during autophagosome formation in Saccharomyces cerevisiae. J Cell Sci (2013) 1.42
Structural basis of Atg8 activation by a homodimeric E1, Atg7. Mol Cell (2011) 1.38
Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p. J Biol Chem (2010) 1.34
Structure-function relationship of Atg12, a ubiquitin-like modifier essential for autophagy. Autophagy (2005) 1.32
Identification of Tam41 maintaining integrity of the TIM23 protein translocator complex in mitochondria. J Cell Biol (2006) 1.30
Interrelationships among Atg proteins during autophagy in Saccharomyces cerevisiae. Yeast (2004) 1.28
A sorting nexin PpAtg24 regulates vacuolar membrane dynamics during pexophagy via binding to phosphatidylinositol-3-phosphate. Mol Biol Cell (2004) 1.26
The first molecular evidence that autophagy relates rimmed vacuole formation in chloroquine myopathy. J Biochem (2002) 1.24
Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method. FEBS Lett (2002) 1.22
Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b. Proc Natl Acad Sci U S A (2011) 1.21
Autophagy-related protein 8 (Atg8) family interacting motif in Atg3 mediates the Atg3-Atg8 interaction and is crucial for the cytoplasm-to-vacuole targeting pathway. J Biol Chem (2010) 1.20
Modification of a ubiquitin-like protein Paz2 conducted micropexophagy through formation of a novel membrane structure. Mol Biol Cell (2003) 1.20
Highly oxidized peroxisomes are selectively degraded via autophagy in Arabidopsis. Plant Cell (2013) 1.18
Dimeric coiled-coil structure of Saccharomyces cerevisiae Atg16 and its functional significance in autophagy. J Biol Chem (2009) 1.17
Role of the Apg12 conjugation system in mammalian autophagy. Int J Biochem Cell Biol (2003) 1.15
Structure-based analyses reveal distinct binding sites for Atg2 and phosphoinositides in Atg18. J Biol Chem (2012) 1.13
Atg12-Atg5 conjugate enhances E2 activity of Atg3 by rearranging its catalytic site. Nat Struct Mol Biol (2013) 1.11
PtdIns 3-Kinase Orchestrates Autophagosome Formation in Yeast. J Lipids (2011) 1.11
Lap3 is a selective target of autophagy in yeast, Saccharomyces cerevisiae. Biochem Biophys Res Commun (2008) 1.10
Autophagy-related protein 32 acts as autophagic degron and directly initiates mitophagy. J Biol Chem (2012) 1.09