Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for glioma.

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Published in Hum Gene Ther on September 24, 2012

Authors

Richard A Morgan1, Laura A Johnson, Jeremy L Davis, Zhili Zheng, Kevin D Woolard, Elizabeth A Reap, Steven A Feldman, Nachimuthu Chinnasamy, Chien-Tsun Kuan, Hua Song, Wei Zhang, Howard A Fine, Steven A Rosenberg

Author Affiliations

1: Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. rmorgan@mail.nih.gov

Associated clinical trials:

CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII | NCT01454596

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