Published in Genes Chromosomes Cancer on July 01, 1990
Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell (2012) 5.44
Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation. Mol Cell Biol (2007) 1.90
Targeting oncogenic Ras signaling in hematologic malignancies. Blood (2012) 1.67
The role of transgenic mouse models in carcinogen identification. Environ Health Perspect (2003) 0.91
Prognostic Significance of NRAS Gene Mutations in Children with Acute Myelogenous Leukemia. Mediterr J Hematol Infect Dis (2011) 0.81
Genetic alterations during colorectal-tumor development. N Engl J Med (1988) 26.82
Mutations in the p53 gene occur in diverse human tumour types. Nature (1989) 13.62
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science (1989) 11.53
Identification of FAP locus genes from chromosome 5q21. Science (1991) 11.41
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science (1992) 10.12
Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (1990) 8.32
p53 function and dysfunction. Cell (1992) 7.73
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science (1991) 6.15
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res (1990) 5.70
Allelotype of colorectal carcinomas. Science (1989) 5.54
The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol (1986) 5.27
The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nat Genet (1996) 4.59
Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells. J Immunol (1984) 4.55
CD34: structure, biology, and clinical utility. Blood (1996) 4.41
Postoperative chemotherapy and delayed radiation in children less than three years of age with malignant brain tumors. N Engl J Med (1993) 4.28
Clonal analysis using recombinant DNA probes from the X-chromosome. Cancer Res (1987) 4.25
Monitoring for anthracycline cardiotoxicity. Pediatrics (1994) 4.05
Effects of health insurance and race on early detection of cancer. J Natl Cancer Inst (1999) 3.99
Clonal origin bladder cancer. N Engl J Med (1992) 3.97
Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac. Nat Genet (2001) 3.65
A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells. Blood (1992) 3.18
Complications of cardiac resuscitation. Chest (1987) 2.42
Racial differences in the survival of childhood B-precursor acute lymphoblastic leukemia: a Pediatric Oncology Group Study. J Clin Oncol (2000) 2.40
Effects of health insurance and race on breast carcinoma treatments and outcomes. Cancer (2000) 2.39
Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor. EMBO J (1997) 2.26
Effects of health insurance and race on colorectal cancer treatments and outcomes. Am J Public Health (2000) 2.26
The effects of physician supply on the early detection of colorectal cancer. J Fam Pract (1999) 2.22
Outcome of unrelated donor bone marrow transplantation in 40 children with Hurler syndrome. Blood (1996) 2.19
Red cells from glutathione peroxidase-1-deficient mice have nearly normal defenses against exogenous peroxides. Blood (2000) 2.19
Flow cytometric analysis of human bone marrow. II. Normal B lymphocyte development. Blood (1987) 2.15
Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies. Cancer Res (1997) 2.12
Hinges, swivels and switches: the role of prolines in signalling via transmembrane alpha-helices. Trends Pharmacol Sci (2000) 2.08
Poly(A) tail shortening is the translation-dependent step in c-myc mRNA degradation. Mol Cell Biol (1990) 2.06
Drug product selection: the Florida experience. Am J Public Health (1980) 2.02
Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility. J Biol Chem (1997) 2.01
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498. Blood (1992) 1.97
Direct demonstration of elevated aldehyde dehydrogenase in human hematopoietic progenitor cells. Blood (1990) 1.88
Relevance of correlates of infant deaths for significant morbidity at 1 year of age. Am J Obstet Gynecol (1980) 1.85
Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol (2001) 1.82
The role of a conserved proline residue in mediating conformational changes associated with voltage gating of Cx32 gap junctions. Biophys J (1999) 1.82
Work-based antipoverty programs for parents can enhance the school performance and social behavior of children. Child Dev (2001) 1.81
Second malignancies in young children with primary brain tumors following treatment with prolonged postoperative chemotherapy and delayed irradiation: a Pediatric Oncology Group study. Ann Neurol (1998) 1.76
Clinical severity and quality of life in children and adolescents with Rett syndrome. Neurology (2011) 1.72
Interval between symptom onset and diagnosis of pediatric solid tumors. J Pediatr (1991) 1.71
Long-term survival in Hodgkin's disease relative impact of mortality, second tumors, infection, and cardiovascular disease. Cancer J Sci Am (2006) 1.70
Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias. Blood (1996) 1.70
The spectrum of Evans' syndrome. Arch Dis Child (1997) 1.69
Comparison of viable cell counts and fluorescence in situ hybridization using specific rRNA-based probes for the quantification of human fecal bacteria. FEMS Microbiol Lett (2000) 1.65
Carrier detection in X-linked agammaglobulinemia by analysis of X-chromosome inactivation. N Engl J Med (1987) 1.63
Flow cytometric analysis of human bone marrow: I. Normal erythroid development. Blood (1987) 1.60
Confrontation visual field techniques in the detection of anterior visual pathway lesions. Ann Neurol (1981) 1.59
Activated N-ras controls the transformed phenotype of HT1080 human fibrosarcoma cells. Cell (1987) 1.58
Increasing supplies of dermatologists and family physicians are associated with earlier stage of melanoma detection. J Am Acad Dermatol (2000) 1.57
The estrogen receptor CpG island is methylated in most hematopoietic neoplasms. Cancer Res (1996) 1.56
An automated communication system in a contact registry for persons with rare diseases: scalable tools for identifying and recruiting clinical research participants. Contemp Clin Trials (2008) 1.52
Complications of CPR. Crit Care Med (1981) 1.52
Frequent detection of tumor cells in hematopoietic grafts in neuroblastoma and Ewing's sarcoma. Bone Marrow Transplant (1998) 1.51
Levels of p53 protein increase with maturation in human hematopoietic cells. Cancer Res (1991) 1.49
Aortic valve replacement with stentless porcine aortic bioprosthesis. J Thorac Cardiovasc Surg (1990) 1.46
The DCC gene: structural analysis and mutations in colorectal carcinomas. Genomics (1994) 1.46
Prognostic importance of immunophenotyping in adults with acute myelocytic leukaemia: the significance of the stem-cell glycoprotein CD34 (My10) Br J Haematol (1990) 1.45
Prognostic factors for patients with Hodgkin disease in first relapse. Cancer (1993) 1.42
Low or absent SPARC expression in acute myeloid leukemia with MLL rearrangements is associated with sensitivity to growth inhibition by exogenous SPARC protein. Leukemia (2006) 1.42
Comparison of iodine-125-BMIPP and thallium-201 in myocardial hypoperfusion. J Nucl Med (1995) 1.40
The treatment of malignant brain tumors in infants and very young children: an update of the Pediatric Oncology Group experience. Neuro Oncol (1999) 1.40
Prognostic factors for positive surgical staging in patients with Hodgkin's disease. J Clin Oncol (1990) 1.39
Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria. Diabetes (2001) 1.38
Functional microdomains in G-protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor. J Biol Chem (1998) 1.37
Molecular mechanisms of ligand interaction with the gonadotropin-releasing hormone receptor. Endocr Rev (1997) 1.37
Indexes of severity: underlying concepts. Health Serv Res (1976) 1.36
Human AML cells in NOD/SCID mice: engraftment potential and gene expression. Leukemia (2002) 1.30
Functional role of a conserved motif in TM6 of the rat mu opioid receptor: constitutively active and inactive receptors result from substitutions of Thr6.34(279) with Lys and Asp. Biochemistry (2001) 1.29
Flow cytometric analysis of human bone marrow. IV. Differential quantitative expression of T-200 common leukocyte antigen during normal hemopoiesis. J Immunol (1988) 1.29
First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes. J Pediatr (2001) 1.29
Antagonism of histamine-activated adenylate cyclase in brain by D-lysergic acid diethylamide. Proc Natl Acad Sci U S A (1977) 1.29
Interactive construction of residue-based diagrams of proteins: the RbDe web service. Protein Eng (2000) 1.29
Structure and dynamics of calmodulin in solution. Biophys J (1998) 1.27
A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor. Mol Pharmacol (1994) 1.25
Rituximab and FAB/LMB 96 chemotherapy in children with Stage III/IV B-cell non-Hodgkin lymphoma: a Children's Oncology Group report. Leukemia (2012) 1.25
Prokink: a protocol for numerical evaluation of helix distortions by proline. Protein Eng (2000) 1.24
Antigenic analysis of hematopoiesis. V. Characterization of My-10 antigen expression by normal lymphohematopoietic progenitor cells. Exp Hematol (1986) 1.24
Has the breast cancer gene been found? Cell (1994) 1.23
Hemoglobin autoxidation and regulation of endogenous H2O2 levels in erythrocytes. Free Radic Biol Med (2005) 1.23
My-1, the human myeloid-specific antigen detected by mouse monoclonal antibodies, is a sugar sequence found in lacto-N-fucopentaose III. Blood (1983) 1.23
Myeloid and megakaryocytic properties of K-562 cell lines. Cancer Res (1983) 1.23
Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis. J Clin Invest (1999) 1.23
A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice. Biochemistry (1998) 1.21
Altered cytoplasmic/nuclear distribution of the c-myc protein in differentiating ML-1 human myeloid leukemia cells. Cell Growth Differ (1993) 1.21
A detailed interpretation of OH radical footprints in a TBP-DNA complex reveals the role of dynamics in the mechanism of sequence-specific binding. J Mol Biol (2000) 1.21
Purification of human erythroid colony-forming units and demonstration of specific binding of erythropoietin. J Clin Invest (1987) 1.21
Final results of a study of escalating doses of hyperfractionated radiotherapy in brain stem tumors in children: a Pediatric Oncology Group study. Int J Radiat Oncol Biol Phys (1993) 1.20
Inhibition of FLT3-mediated transformation by use of a tyrosine kinase inhibitor. Leukemia (2001) 1.20
Antigenic analysis of hematopoiesis. VI. Flow cytometric characterization of My-10-positive progenitor cells in normal human bone marrow. Exp Hematol (1987) 1.19
Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains. Biophys J (1992) 1.19
Myeloblasts from Down syndrome children with acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin. Leukemia (1997) 1.18
Eight lipooligosaccharides of Neisseria meningitidis react with a monoclonal antibody which binds lacto-N-neotetraose (Gal beta 1-4GlcNAc beta 1-3Gal beta 1-4Glc). Infect Immun (1991) 1.18