Daru Lu

Author PubWeight™ 127.22‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genetic evidence supports demic diffusion of Han culture. Nature 2004 2.92
2 A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet 2011 2.85
3 Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet 2012 2.26
4 Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer Res 2009 1.94
5 Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4. Nat Genet 2012 1.78
6 Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma. Neurosci Res 2006 1.67
7 Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans. Am J Hum Genet 2004 1.57
8 Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin. J Clin Invest 2006 1.53
9 Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. Nat Genet 2012 1.49
10 Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells. Nucleic Acids Res 2013 1.48
11 Rationales, design and recruitment of the Taizhou Longitudinal Study. BMC Public Health 2009 1.39
12 Paternal genetic affinity between Western Austronesians and Daic populations. BMC Evol Biol 2008 1.33
13 A meta-analysis of association between C677T polymorphism in the methylenetetrahydrofolate reductase gene and hypertension. Eur J Hum Genet 2007 1.32
14 Rapid quantification of DNA methylation by measuring relative peak heights in direct bisulfite-PCR sequencing traces. Lab Invest 2009 1.32
15 Systematic confirmation study of reported prostate cancer risk-associated single nucleotide polymorphisms in Chinese men. Cancer Sci 2011 1.32
16 Tagging SNPs in non-homologous end-joining pathway genes and risk of glioma. Carcinogenesis 2007 1.30
17 Polymorphisms of LIG4 and XRCC4 involved in the NHEJ pathway interact to modify risk of glioma. Hum Mutat 2008 1.26
18 Association of sequence variants on chromosomes 20, 11, and 5 (20q13.33, 11q23.3, and 5p15.33) with glioma susceptibility in a Chinese population. Am J Epidemiol 2011 1.17
19 Functional polymorphisms of matrix metalloproteinase-9 are associated with risk of occurrence and metastasis of lung cancer. Clin Cancer Res 2005 1.16
20 Replication and cumulative effects of GWAS-identified genetic variations for prostate cancer in Asians: a case-control study in the ChinaPCa consortium. Carcinogenesis 2011 1.15
21 A novel germline mutation in HOXB13 is associated with prostate cancer risk in Chinese men. Prostate 2012 1.15
22 Genetic variants in the MDM2 promoter and lung cancer risk in a Chinese population. Int J Cancer 2006 1.14
23 A polymorphism of microRNA196a genome region was associated with decreased risk of glioma in Chinese population. J Cancer Res Clin Oncol 2010 1.13
24 Predictive performance of prostate cancer risk in Chinese men using 33 reported prostate cancer risk-associated SNPs. Prostate 2011 1.10
25 REV3L confers chemoresistance to cisplatin in human gliomas: the potential of its RNAi for synergistic therapy. Neuro Oncol 2009 1.09
26 Genetic structure of Hmong-Mien speaking populations in East Asia as revealed by mtDNA lineages. Mol Biol Evol 2004 1.07
27 Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy. Clin Cancer Res 2012 1.05
28 Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility. FASEB J 2009 1.04
29 Association of polymorphisms in one-carbon metabolizing genes and lung cancer risk: a case-control study in Chinese population. Lung Cancer 2008 1.04
30 Analysis of specialized DNA polymerases expression in human gliomas: association with prognostic significance. Neuro Oncol 2010 1.03
31 Predictive value of XRCC1 gene polymorphisms on platinum-based chemotherapy in advanced non-small cell lung cancer patients: a systematic review and meta-analysis. Clin Cancer Res 2012 1.02
32 Genome-wide association study identifies novel loci associated with serum level of vitamin B12 in Chinese men. Hum Mol Genet 2012 1.02
33 Functional promoter -1271G>C variant of HSPB1 predicts lung cancer risk and survival. J Clin Oncol 2010 1.02
34 Effect of mu-opioid receptor gene polymorphisms on heroin-induced subjective responses in a Chinese population. Biol Psychiatry 2006 1.01
35 Association of XPD polymorphisms with severe toxicity in non-small cell lung cancer patients in a Chinese population. Clin Cancer Res 2009 1.00
36 Association of ABCC2 polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients. Lung Cancer 2010 1.00
37 Evaluation of reported prostate cancer risk-associated SNPs from genome-wide association studies of various racial populations in Chinese men. Prostate 2013 1.00
38 Hypermethylation of hepatic glucokinase and L-type pyruvate kinase promoters in high-fat diet-induced obese rats. Endocrinology 2011 0.98
39 Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese. Am J Hum Genet 2012 0.98
40 XRCC3 haplotypes and risk of gliomas in a Chinese population: a hospital-based case-control study. Int J Cancer 2009 0.97
41 Expression analyses of 27 DNA repair genes in astrocytoma by TaqMan low-density array. Neurosci Lett 2006 0.96
42 Upregulation of miR-15b in NAFLD models and in the serum of patients with fatty liver disease. Diabetes Res Clin Pract 2012 0.95
43 Dinucleotide polymorphism of p73 gene is associated with a reduced risk of lung cancer in a Chinese population. Int J Cancer 2005 0.93
44 Atoh8, a bHLH transcription factor, is required for the development of retina and skeletal muscle in zebrafish. PLoS One 2010 0.93
45 Polymorphisms in hMLH1 and risk of early-onset lung cancer in a southeast Chinese population. Lung Cancer 2007 0.92
46 Genetic polymorphisms in DNA double-strand break repair genes XRCC5, XRCC6 and susceptibility to hepatocellular carcinoma. Carcinogenesis 2011 0.91
47 Fine-mapping of a region of chromosome 5p15.33 (TERT-CLPTM1L) suggests a novel locus in TERT and a CLPTM1L haplotype are associated with glioma susceptibility in a Chinese population. Int J Cancer 2012 0.91
48 Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis. Lung Cancer 2008 0.91
49 Two polymorphisms in NEDD4L gene and essential hypertension in Chinese Hans - a population-based case-control study. Clin Exp Hypertens 2008 0.91
50 Fine mapping analysis of a region of 20q13.33 identified five independent susceptibility loci for glioma in a Chinese Han population. Carcinogenesis 2012 0.90
51 Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in han chinese. PLoS Genet 2013 0.90
52 Synergy between IL-6 and TGF-β signaling promotes FOXP3 degradation. Int J Clin Exp Pathol 2012 0.90
53 Genetic variant in TP63 on locus 3q28 is associated with risk of lung adenocarcinoma among never-smoking females in Asia. Hum Genet 2012 0.90
54 Allele 2 of the interleukin-1 receptor antagonist gene (IL1RN*2) is associated with a decreased risk of primary lung cancer. Cancer Lett 2005 0.89
55 Prediction of lung cancer risk in a Chinese population using a multifactorial genetic model. BMC Med Genet 2012 0.89
56 SPP1 promoter polymorphisms and glioma risk in a Chinese Han population. J Hum Genet 2010 0.89
57 Association of human aryl hydrocarbon receptor gene polymorphisms with risk of lung cancer among cigarette smokers in a Chinese population. Pharmacogenet Genomics 2009 0.89
58 Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: a haplotype-based analysis. Hum Mutat 2007 0.88
59 Locked nucleic acid pentamers as universal PCR primers for genomic DNA amplification. PLoS One 2008 0.88
60 Polymorphisms in the two helicases ERCC2/XPD and ERCC3/XPB of the transcription factor IIH complex and risk of lung cancer: a case-control analysis in a Chinese population. Cancer Epidemiol Biomarkers Prev 2006 0.87
61 A promoter polymorphism (-77T>C) of DNA repair gene XRCC1 is associated with risk of lung cancer in relation to tobacco smoking. Pharmacogenet Genomics 2005 0.87
62 Genetic variants in peroxisome proliferator-activated receptor-gamma gene are associated with risk of lung cancer in a Chinese population. Carcinogenesis 2008 0.87
63 A two-SNP IL-6 promoter haplotype is associated with increased lung cancer risk. J Cancer Res Clin Oncol 2012 0.87
64 Effect of polymorphisms in XPD on clinical outcomes of platinum-based chemotherapy for Chinese non-small cell lung cancer patients. PLoS One 2012 0.87
65 Single nucleotide polymorphisms in IL-4Ra, IL-13 and STAT6 genes occurs in brain glioma. Front Biosci (Elite Ed) 2011 0.86
66 Tagging single nucleotide polymorphisms in excision repair cross-complementing group 1 (ERCC1) and risk of primary lung cancer in a Chinese population. Pharmacogenet Genomics 2007 0.86
67 Sequence variations in DNA repair gene XPC is associated with lung cancer risk in a Chinese population: a case-control study. BMC Cancer 2007 0.86
68 Associations of common polymorphisms in GCKR with type 2 diabetes and related traits in a Han Chinese population: a case-control study. BMC Med Genet 2011 0.86
69 A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population. BMC Cancer 2011 0.86
70 Polymorphisms in excision repair cross-complementing group 4 (ERCC4) and susceptibility to primary lung cancer in a Chinese Han population. Lung Cancer 2008 0.86
71 Significant association of 5p15.33 (TERT-CLPTM1L genes) with lung cancer in Chinese Han population. Exp Lung Res 2013 0.86
72 Effects of O6-methylguanine-DNA methyltransferase (MGMT) polymorphisms on cancer: a meta-analysis. Mutagenesis 2009 0.85
73 Association between CASP8 and CASP10 polymorphisms and toxicity outcomes with platinum-based chemotherapy in Chinese patients with non-small cell lung cancer. Oncologist 2012 0.85
74 Association between EGF +61 G/A and glioma risk in a Chinese population. BMC Cancer 2010 0.85
75 The influence of metabolic gene polymorphisms on urinary 1-hydroxypyrene concentrations in Chinese coke oven workers. Sci Total Environ 2007 0.85
76 Polymorphisms in DNA damage binding protein 2 (DDB2) and susceptibility of primary lung cancer in the Chinese: a case-control study. Carcinogenesis 2006 0.85
77 Association of the variable number of tandem repeats polymorphism in the promoter region of the SMYD3 gene with risk of esophageal squamous cell carcinoma in relation to tobacco smoking. Cancer Sci 2008 0.85
78 Association of prostate cancer risk with SNPs in regions containing androgen receptor binding sites captured by ChIP-On-chip analyses. Prostate 2011 0.85
79 Hsa-miR-196a2 functional SNP is associated with severe toxicity after platinum-based chemotherapy of advanced nonsmall cell lung cancer patients in a Chinese population. J Clin Lab Anal 2012 0.85
80 Pax4 paired domain mediates direct protein transduction into mammalian cells. Endocrinology 2007 0.84
81 A novel type of PTD, common helix-loop-helix motif, could efficiently mediate protein transduction into mammalian cells. Biochem Biophys Res Commun 2006 0.84
82 Hypermethylation reduces expression of tumor-suppressor PLZF and regulates proliferation and apoptosis in non-small-cell lung cancers. FASEB J 2013 0.84
83 Genetic polymorphisms in XRCC1, APE1, ADPRT, XRCC2, and XRCC3 and risk of chronic benzene poisoning in a Chinese occupational population. Cancer Epidemiol Biomarkers Prev 2005 0.84
84 A common polymorphism rs3781637 in MTNR1B is associated with type 2 diabetes and lipids levels in Han Chinese individuals. Cardiovasc Diabetol 2011 0.84
85 Association of POLK polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients. Cell Biochem Biophys 2014 0.84
86 Genetic susceptibility of lung cancer associated with common variants in the 3' untranslated regions of the adenosine triphosphate-binding cassette B1 (ABCB1) and ABCC1 candidate transporter genes for carcinogen export. Cancer 2009 0.83
87 The rs522616 polymorphism in the matrix metalloproteinase-3 (MMP-3) gene is associated with sporadic brain arteriovenous malformation in a Chinese population. J Clin Neurosci 2010 0.83
88 Functionally significant nicotine acetylcholine receptor subunit α5 promoter haplotypes are associated with susceptibility to lung cancer in Chinese. Cancer 2011 0.83
89 A variant in the CHEK2 promoter at a methylation site relieves transcriptional repression and confers reduced risk of lung cancer. Carcinogenesis 2010 0.82
90 Common polymorphism rs11191548 near the CYP17A1 gene is associated with hypertension and systolic blood pressure in the Han Chinese population. Am J Hypertens 2013 0.81
91 pH-sensitive poly(glutamic acid) grafted mesoporous silica nanoparticles for drug delivery. Int J Pharm 2013 0.81
92 Selective histonedeacetylase inhibitor M344 intervenes in HIV-1 latency through increasing histone acetylation and activation of NF-kappaB. PLoS One 2012 0.81
93 Fine mapping of a region of chromosome 11q23.3 reveals independent locus associated with risk of glioma. PLoS One 2012 0.81
94 ERCC6/CSB gene polymorphisms and lung cancer risk. Cancer Lett 2008 0.81
95 Association between polymorphisms in the GSTA4 gene and risk of lung cancer: a case-control study in a Southeastern Chinese population. Mol Carcinog 2009 0.81
96 Multifractal Analysis of Genomic Sequences CGR Images. Conf Proc IEEE Eng Med Biol Soc 2005 0.80
97 Myostatin gene mutated mice induced with tale nucleases. Anim Biotechnol 2015 0.80
98 Methyl-CpG binding domain 1 gene polymorphisms and lung cancer risk in a Chinese population. Biomarkers 2008 0.80
99 Allelic variation of the MMP3 promoter affects transcription activity through the transcription factor C-MYB in human brain arteriovenous malformations. PLoS One 2013 0.80
100 Tagging single nucleotide polymorphisms in MBD4 are associated with risk of lung cancer in a Chinese population. Lung Cancer 2008 0.79
101 [Multifractal analysis of genomes sequences' CGR graph]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2007 0.79
102 Cloning, expression, and functional characterization of zebrafish Mist1. Biochem Biophys Res Commun 2007 0.79
103 Association between genetic variations of vascular endothelial growth factor receptor 2 and glioma in the Chinese Han population. J Mol Neurosci 2012 0.79
104 Beta-2 adrenergic receptor gene (ADRB2) polymorphism and risk for lung adenocarcinoma: a case-control study in a Chinese population. Cancer Lett 2005 0.79
105 A novel CCM1 gene mutation causes cerebral cavernous malformation in a Chinese family. J Clin Neurosci 2010 0.79
106 Genetic variants in GTF2H1 and risk of lung cancer: a case-control analysis in a Chinese population. Lung Cancer 2008 0.79
107 Inhibition of hepatitis B virus (HBV) by LNA-mediated nuclear interference with HBV DNA transcription. Biochem Biophys Res Commun 2011 0.79
108 Possible association between genetic variants in the H2AFX promoter region and risk of adult glioma in a Chinese Han population. J Neurooncol 2011 0.79
109 Molecular cloning and expression of two closely related GTP-binding proteins from zebrafish. DNA Seq 2004 0.79
110 Molecular cloning, characterization, and developmental expression of foxp1 in zebrafish. Dev Genes Evol 2007 0.79
111 Single nucleotide polymorphisms of matrix metallopeptidase 3 and risk of gliomas in a Chinese Han population. Mol Carcinog 2011 0.78
112 Polymorphisms of the vascular endothelial growth factor A gene and susceptibility to sporadic brain arteriovenous malformation in a Chinese population. J Clin Neurosci 2011 0.78
113 Association of CASP3 polymorphism with hematologic toxicity in patients with advanced non-small-cell lung carcinoma treated with platinum-based chemotherapy. Cancer Sci 2012 0.78
114 Complete sequence data support lack of balancing selection on PRNP in a natural Chinese population. J Hum Genet 2006 0.78
115 Association study of four activity SNPs of CYP3A4 with the precocious puberty in Chinese girls. Neurosci Lett 2005 0.78
116 Overexpression of SLC7A7 predicts poor progression-free and overall survival in patients with glioblastoma. Med Oncol 2013 0.77
117 Transplantation of rat islets transduced with human heme oxygenase-1 gene using adenovirus vector. Pancreas 2006 0.77
118 GSTP1 A1578G (Ile105Val) polymorphism in benzidine-exposed workers: an association with cytological grading of exfoliated urothelial cells. Pharmacogenetics 2003 0.77
119 Heterozygote advantage of methylenetetrahydrofolate reductase polymorphisms on clinical outcomes in advanced non-small cell lung cancer (NSCLC) patients treated with platinum-based chemotherapy. Tumour Biol 2014 0.77
120 Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility. Clin Cancer Res 2008 0.77
121 CTLA4 A49G polymorphism shows significant association with glioma risk in a Chinese population. Biochem Genet 2010 0.77
122 Association of CASP7 polymorphisms and survival of patients with non-small cell lung cancer with platinum-based chemotherapy treatment. Chest 2012 0.77
123 Iodoacetic acid activates Nrf2-mediated antioxidant response in vitro and in vivo. Environ Sci Technol 2014 0.76
124 Muscle injection of rAAV/mFIX to secrete clotting factor IX corrects the hemorrhagic tendencies in hemophilia B mice. Sci China C Life Sci 2003 0.76
125 Association study of six activity SNPS in adrenal steroid hormone metabolism and IBM related genes with precocious puberty in Chinese girls. Neuro Endocrinol Lett 2006 0.76
126 Polymorphisms of CAK genes and risk for lung cancer: a case-control study in Chinese population. Lung Cancer 2007 0.76
127 Possible association between polymorphisms of human vascular endothelial growth factor A gene and susceptibility to glioma in a Chinese population. Int J Cancer 2011 0.76
128 Genetic variants in N-myc (and STAT) interactor and susceptibility to glioma in a Chinese Han population. Tumour Biol 2014 0.76
129 The rs9509 polymorphism of MMP-9 is associated with risk of hemorrhage in brain arteriovenous malformations. J Clin Neurosci 2012 0.76
130 Improvement of combination chemotherapy tolerance by introduction of polycistronic retroviral vector drug resistance genes MGMT and MDR1 into human umbilical cord blood CD34+ cells. Leuk Res 2002 0.76
131 Common genetic variations of the cytochrome P450 1A1 gene and risk of hepatocellular carcinoma in a Chinese population. Eur J Cancer 2008 0.75
132 Facile phase transfer of hydrophobic nanoparticles with poly(ethylene glycol) grafted hyperbranched poly(amido amine). Nanotechnology 2009 0.75
133 Matrix metalloproteinase-2 polymorphisms and clinical outcome of Chinese patients with nonsmall cell lung cancer treated with first-line, platinum-based chemotherapy. Cancer 2011 0.75
134 [Alignment-free biomolecular sequence comparison method]. Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 2005 0.75
135 Association of genetic variants in the retinoblastoma binding protein 6 gene with the risk of glioma: a case-control study in a Chinese Han population. J Neurosurg 2014 0.75
136 [Analysis of mutation sites of BRCA1 gene in Chinese patients with breast cancer]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2002 0.75
137 [Analysis of three Y-STR loci polymorphism in isolated populations]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2002 0.75
138 [Two single nucleotide polymorphisms of beta 2-adrenoceptor gene in elderly patients with hypertension]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2002 0.75
139 [Construction and Expression of Retroviral Vector Encoding Enhanced Green Fluorescent Protein] Zhongguo Shi Yan Xue Ye Xue Za Zhi 2000 0.75
140 Redox- and temperature-controlled drug release from hollow mesoporous silica nanoparticles. Chemistry 2013 0.75
141 Recombinant MafA protein containing its own protein transduction domain stimulates insulin gene expression in IEC-6 cells. Life Sci 2011 0.75
142 A preliminary genetic distinctness of four Coilia fishes (Clupeiformes: Engraulidae) inferred from mitochondrial DNA sequences. Genetika 2008 0.75
143 Overexpression of eukaryotic elongation factor 1 alpha-2 is associated with poorer prognosis in patients with gastric cancer. J Cancer Res Clin Oncol 2015 0.75
144 Enhancement of recombinant human ADAM15 disintegrin domain expression level by releasing the rare codons and amino acids restriction. Appl Biochem Biotechnol 2008 0.75
145 Association of CDC25 phosphatase family polymorphisms with the efficacy/toxicity of platinum-based chemotherapy in Chinese advanced NSCLC patients. Future Oncol 2014 0.75
146 Expression, purification, and characterization of formaldehyde dehydrogenase from Pseudomonas aeruginosa. Protein Expr Purif 2013 0.75