Published in Sci Signal on July 17, 2012
Role of ABL family kinases in cancer: from leukaemia to solid tumours. Nat Rev Cancer (2013) 1.92
Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes. Cell Mol Life Sci (2014) 1.15
The capable ABL: what is its biological function? Mol Cell Biol (2014) 1.00
Crk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton. Genes Cancer (2012) 0.86
CRK proteins selectively regulate T cell migration into inflamed tissues. J Clin Invest (2015) 0.84
Multifunctional Abl kinases in health and disease. J Cell Sci (2016) 0.83
Adaptors for disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease. Oncoscience (2014) 0.82
CAS proteins in health and disease: an update. IUBMB Life (2014) 0.82
Abl family kinases regulate endothelial barrier function in vitro and in mice. PLoS One (2013) 0.82
The Emerging Role of ABL Kinases in Solid Tumors. Trends Cancer (2015) 0.81
Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages. J Immunol (2012) 0.81
Preclinical and clinical studies of the NEDD9 scaffold protein in cancer and other diseases. Gene (2015) 0.81
High expression of HEF1 is associated with poor prognosis in urinary bladder carcinoma. Onco Targets Ther (2014) 0.80
The Abl/enabled signaling pathway regulates Golgi architecture in Drosophila photoreceptor neurons. Mol Biol Cell (2014) 0.78
Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility. PLoS One (2015) 0.77
NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer. Oncogene (2014) 0.77
Tyrosine kinases EnAbling adaptor molecules for chemokine-induced Rap1 activation in T cells. Sci Signal (2012) 0.75
Inactivation of ABL kinases suppresses non-small cell lung cancer metastasis. JCI Insight (2016) 0.75
The Role of Crk Adaptor Proteins in T-Cell Adhesion and Migration. Front Immunol (2015) 0.75
Cell migration: (en)ABLing T cell migration. Nat Rev Immunol (2012) 0.75
Orchestrating the orchestrators: chemokines in control of T cell traffic. Nat Immunol (2008) 4.17
Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases. Curr Biol (1995) 3.12
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow. J Cell Biol (2003) 2.40
Integrin signalling: a new Cas(t) of characters enters the stage. Trends Cell Biol (2000) 2.39
Requirement for Abl kinases in T cell receptor signaling. Curr Biol (2004) 2.24
How chemokines invite leukocytes to dance. Nat Immunol (2008) 2.18
Homeostatic chemokine receptors and organ-specific metastasis. Nat Rev Immunol (2011) 1.98
ABL tyrosine kinases: evolution of function, regulation, and specificity. Sci Signal (2010) 1.91
Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts. J Cell Sci (2009) 1.78
Abl tyrosine kinases are required for infection by Shigella flexneri. EMBO J (2003) 1.59
Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion. Mol Cell Biol (2006) 1.53
Defective T cell development and function in the absence of Abelson kinases. J Immunol (2007) 1.49
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse. Blood (2008) 1.48
Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo. Blood (2004) 1.48
G protein-coupled receptors stimulation and the control of cell migration. Cell Signal (2009) 1.46
Molecular basis for HEF1/NEDD9/Cas-L action as a multifunctional co-ordinator of invasion, apoptosis and cell cycle. Cell Biochem Biophys (2007) 1.45
Abl tyrosine kinases regulate cell-cell adhesion through Rho GTPases. Proc Natl Acad Sci U S A (2007) 1.43
Activation of Rap1 promotes prostate cancer metastasis. Cancer Res (2009) 1.41
Essential role for Rap1 GTPase and its guanine exchange factor CalDAG-GEFI in LFA-1 but not VLA-4 integrin mediated human T-cell adhesion. Blood (2007) 1.41
First-line treatment for chronic myeloid leukemia: dasatinib, nilotinib, or imatinib. J Hematol Oncol (2010) 1.40
The Par polarity complex regulates Rap1- and chemokine-induced T cell polarization. J Cell Biol (2007) 1.38
Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions. Blood (2005) 1.33
Adhesion-dependent regulation of p190RhoGAP in the developing brain by the Abl-related gene tyrosine kinase. Curr Biol (2004) 1.30
The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1. J Cell Biol (2008) 1.23
Abl kinases are required for invadopodia formation and chemokine-induced invasion. J Biol Chem (2010) 1.20
Intracellular mediators of CXCR4-dependent signaling in T cells. Immunol Lett (2007) 1.19
The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking. Immunity (2006) 1.15
Critical roles for Rac GTPases in T-cell migration to and within lymph nodes. Blood (2010) 1.11
Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes. J Biol Chem (1994) 1.10
Abl tyrosine kinases in T-cell signaling. Immunol Rev (2009) 1.04
Lck is required for stromal cell-derived factor 1 alpha (CXCL12)-induced lymphoid cell chemotaxis. Blood (2002) 1.02
Cellular polarization induced by chemokines: a mechanism for leukocyte recruitment? Immunol Today (1996) 0.97
The non-receptor tyrosine kinase Lyn controls neutrophil adhesion by recruiting the CrkL-C3G complex and activating Rap1 at the leading edge. J Cell Sci (2011) 0.92
Imatinib mesylate both prevents and treats the arthritis induced by type II collagen antibody in mice. Mod Rheumatol (2007) 0.92
Arg kinase regulates epithelial cell polarity by targeting β1-integrin and small GTPase pathways. Curr Biol (2011) 0.92
Comparative suppressive effects of tyrosine kinase inhibitors imatinib and nilotinib in models of autoimmune arthritis. Mod Rheumatol (2010) 0.90
Fyn and Lck tyrosine kinases regulate tyrosine phosphorylation of p105CasL, a member of the p130Cas docking protein family, in T-cell receptor-mediated signalling. Immunology (1999) 0.86
Imatinib mesylate inhibited rat adjuvant arthritis and PDGF-dependent growth of synovial fibroblast via interference with the Akt signaling pathway. Mod Rheumatol (2009) 0.83
The differential role of L-selectin and ICAM-1 in Th1-type and Th2-type contact hypersensitivity. J Invest Dermatol (2010) 0.81
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci U S A (2006) 5.95
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. Nat Med (2002) 5.18
Identification and functional analysis of in vivo phosphorylation sites of the Arabidopsis BRASSINOSTEROID-INSENSITIVE1 receptor kinase. Plant Cell (2005) 3.48
CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator. EMBO Rep (2005) 2.80
Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture. Nat Biotechnol (2009) 2.69
BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma. Proc Natl Acad Sci U S A (2002) 2.62
Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance. Mol Cell Biol (2004) 2.24
Requirement for Abl kinases in T cell receptor signaling. Curr Biol (2004) 2.24
An integrated clinico-metabolomic model improves prediction of death in sepsis. Sci Transl Med (2013) 2.23
Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes. Cancer Res (2005) 2.08
Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction. Nat Neurosci (2003) 2.03
Role of ABL family kinases in cancer: from leukaemia to solid tumours. Nat Rev Cancer (2013) 1.92
Site-specific analysis of protein S-acylation by resin-assisted capture. J Lipid Res (2010) 1.77
ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol (2004) 1.70
Abl tyrosine kinases are required for infection by Shigella flexneri. EMBO J (2003) 1.59
A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1. Nat Cell Biol (2003) 1.53
Association of calcineurin with the COPI protein Sec28 and the COPII protein Sec13 revealed by quantitative proteomics. PLoS One (2011) 1.52
Quantitative proteomics reveals metabolic and pathogenic properties of Chlamydia trachomatis developmental forms. Mol Microbiol (2011) 1.51
Defective T cell development and function in the absence of Abelson kinases. J Immunol (2007) 1.49
Abl tyrosine kinases regulate cell-cell adhesion through Rho GTPases. Proc Natl Acad Sci U S A (2007) 1.43
Restraint of apoptosis during mitosis through interdomain phosphorylation of caspase-2. EMBO J (2009) 1.42
Elevated expression of a subset of interferon inducible genes in primary bone marrow cells expressing p185 Bcr-Abl versus p210 Bcr-Abl by DNA microarray analysis. Leuk Res (2004) 1.41
Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels. Mol Cell Biol (2004) 1.38
Abl tyrosine kinase regulates endocytosis of the epidermal growth factor receptor. J Biol Chem (2006) 1.38
Exploiting the complementary nature of LC/MALDI/MS/MS and LC/ESI/MS/MS for increased proteome coverage. J Am Soc Mass Spectrom (2003) 1.37
The protein expression landscape of the Arabidopsis root. Proc Natl Acad Sci U S A (2012) 1.36
Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. Curr Biol (2006) 1.35
Regulation of cell-cell adhesion by Abi/Diaphanous complexes. Mol Cell Biol (2009) 1.33
Abl kinases regulate actin comet tail elongation via an N-WASP-dependent pathway. Mol Cell Biol (2005) 1.31
Abl kinases regulate autophagy by promoting the trafficking and function of lysosomal components. J Biol Chem (2008) 1.25
Identification of S-nitrosylated targets of thioredoxin using a quantitative proteomic approach. Biochemistry (2010) 1.23
Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis. Infect Immun (2010) 1.22
Abl kinases are required for invadopodia formation and chemokine-induced invasion. J Biol Chem (2010) 1.20
Abl tyrosine kinases modulate cadherin-dependent adhesion upstream and downstream of Rho family GTPases. Cell Cycle (2007) 1.16
Bidirectional signaling links the Abelson kinases to the platelet-derived growth factor receptor. Mol Cell Biol (2004) 1.14
Bcr-Abl variants: biological and clinical aspects. Leuk Res (2002) 1.11
Targeting N-cadherin enhances antitumor activity of cytotoxic therapies in melanoma treatment. Cancer Res (2008) 1.11
A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2. Mol Cell (2011) 1.09
The PICALM protein plays a key role in iron homeostasis and cell proliferation. PLoS One (2012) 1.06
Abl tyrosine kinases in T-cell signaling. Immunol Rev (2009) 1.04
Quantitative label-free phosphoproteomics strategy for multifaceted experimental designs. Anal Chem (2011) 1.04
Nitric oxide reduces NADPH oxidase 5 (Nox5) activity by reversible S-nitrosylation. Free Radic Biol Med (2012) 1.02
Kinetic characterization of Salmonella FliK-FlhB interactions demonstrates complexity of the Type III secretion substrate-specificity switch. Biochemistry (2010) 1.01
Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival. Proc Natl Acad Sci U S A (2013) 1.01
Proteomic profiling of a layered tissue reveals unique glycolytic specializations of photoreceptor cells. Mol Cell Proteomics (2010) 1.01
Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium. Blood (2011) 1.00
Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C. PLoS One (2011) 0.98
Resistance to ErbB2 tyrosine kinase inhibitors in breast cancer is mediated by calcium-dependent activation of RelA. Mol Cancer Ther (2010) 0.98
Iron deprivation in cancer--potential therapeutic implications. Nutrients (2013) 0.98
Analysis of oxygen/glucose-deprivation-induced changes in SUMO3 conjugation using SILAC-based quantitative proteomics. J Proteome Res (2011) 0.98
Expression of a testis-specific form of Gal3st1 (CST), a gene essential for spermatogenesis, is regulated by the CTCF paralogous gene BORIS. Mol Cell Biol (2010) 0.96
Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus. Biochem Biophys Res Commun (2013) 0.94
Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin. Proc Natl Acad Sci U S A (2010) 0.94
Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus. PLoS Pathog (2013) 0.94
NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration. PLoS One (2012) 0.93
Identification of a key lysine residue in heat shock protein 90 required for azole and echinocandin resistance in Aspergillus fumigatus. Antimicrob Agents Chemother (2014) 0.93
Arg kinase regulates epithelial cell polarity by targeting β1-integrin and small GTPase pathways. Curr Biol (2011) 0.92
Quantitative proteomics of bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis. J Proteome Res (2015) 0.91
A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis. Blood (2013) 0.90
The Caenorhabditis elegans ABL-1 tyrosine kinase is required for Shigella flexneri pathogenesis. Appl Environ Microbiol (2006) 0.89
Activation and signaling of the Abl tyrosine kinase: bidirectional link with phosphoinositide signaling. Cell Cycle (2003) 0.89
Role of unusual P loop ejection and autophosphorylation in HipA-mediated persistence and multidrug tolerance. Cell Rep (2012) 0.87
Abi-1 forms an epidermal growth factor-inducible complex with Cbl: role in receptor endocytosis. Cell Signal (2007) 0.86
Mass spectrometry-based thermal shift assay for protein-ligand binding analysis. Anal Chem (2010) 0.86
A novel mechanism for CTCF in the epigenetic regulation of Bax in breast cancer cells. Neoplasia (2013) 0.84
Characterization of a new family of protein kinases from Arabidopsis containing phosphoinositide 3/4-kinase and ubiquitin-like domains. Biochem J (2008) 0.84
Proteomic analysis of an unculturable bacterial endosymbiont (Blochmannia) reveals high abundance of chaperonins and biosynthetic enzymes. J Proteome Res (2012) 0.84
Proteomic characterization of the cellular response to nitrosative stress mediated by s-nitrosoglutathione reductase inhibition. J Proteome Res (2012) 0.84
Novel protein purification system utilizing an N-terminal fusion protein and a caspase-3 cleavable linker. Protein Expr Purif (2005) 0.84
A novel interface for variable flow nanoscale LC/MS/MS for improved proteome coverage. J Am Soc Mass Spectrom (2002) 0.84
SH3 domain-based phototrapping in living cells reveals Rho family GAP signaling complexes. Sci Signal (2011) 0.84
Proteomic analysis of human bronchoalveolar lavage fluid after subsgemental exposure. J Proteome Res (2013) 0.83
Proteomic analysis of the NOS2 interactome in human airway epithelial cells. Nitric Oxide (2013) 0.83
Phosphorylation of c-Abl by protein kinase Pak2 regulates differential binding of ABI2 and CRK. Biochemistry (2007) 0.82
Microproteomics: quantitative proteomic profiling of small numbers of laser-captured cells. Cold Spring Harb Protoc (2011) 0.82
Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats. Anesthesiology (2016) 0.81
Abl family kinases regulate FcγR-mediated phagocytosis in murine macrophages. J Immunol (2012) 0.81
Automated, reproducible, titania-based phosphopeptide enrichment strategy for label-free quantitative phosphoproteomics. J Biomol Tech (2013) 0.81
Metaprotein expression modeling for label-free quantitative proteomics. BMC Bioinformatics (2012) 0.81
Location and role of free cysteinyl residues in the Sindbis virus E1 and E2 glycoproteins. J Virol (2007) 0.81
Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest (2016) 0.80
Identification and Quantitation of Coding Variants and Isoforms of Pulmonary Surfactant Protein A. J Proteome Res (2014) 0.80
Longitudinal study of differential protein expression in an Alzheimer's mouse model lacking inducible nitric oxide synthase. J Proteome Res (2013) 0.80
Stress and death: breaking up the c-Abl/14-3-3 complex in apoptosis. Nat Cell Biol (2005) 0.80
Solid-phase capture for the detection and relative quantification of S-nitrosoproteins by mass spectrometry. Methods (2012) 0.79
A mass spectrometry-based proteomic approach to study Marek's Disease Virus gene expression. J Virol Methods (2006) 0.79
Peptide array X-linking (PAX): a new peptide-protein identification approach. PLoS One (2012) 0.78
Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation. Biochemistry (2011) 0.78