Published in Nat Neurosci on July 29, 2012
Growth and folding of the mammalian cerebral cortex: from molecules to malformations. Nat Rev Neurosci (2014) 1.44
Insights into the biological functions of Dock family guanine nucleotide exchange factors. Genes Dev (2014) 1.15
Dynein recruitment to nuclear pores activates apical nuclear migration and mitotic entry in brain progenitor cells. Cell (2013) 1.13
Altered thermogenesis and impaired bone remodeling in Misty mice. J Bone Miner Res (2013) 0.99
TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types. Mol Biol Cell (2014) 0.93
The centrosomal adaptor TACC3 and the microtubule polymerase chTOG interact via defined C-terminal subdomains in an Aurora-A kinase-independent manner. J Biol Chem (2013) 0.91
Regulation of chandelier cell cartridge and bouton development via DOCK7-mediated ErbB4 activation. Cell Rep (2014) 0.90
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation. Biol Open (2015) 0.88
Extra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders. Genes Cells (2013) 0.87
Post-transcriptional regulatory elements and spatiotemporal specification of neocortical stem cells and projection neurons. Neuroscience (2013) 0.86
Mutations in DOCK7 in individuals with epileptic encephalopathy and cortical blindness. Am J Hum Genet (2014) 0.85
Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development. Front Neurosci (2015) 0.84
PKA modulation of Rac in neuronal cells. Front Cell Neurosci (2014) 0.84
The fetal brain transcriptome and neonatal behavioral phenotype in the Ts1Cje mouse model of Down syndrome. Am J Med Genet A (2015) 0.83
A genome-wide association analysis for porcine serum lipid traits reveals the existence of age-specific genetic determinants. BMC Genomics (2014) 0.83
Association between the DOCK7, PCSK9 and GALNT2 Gene Polymorphisms and Serum Lipid levels. Sci Rep (2016) 0.82
The emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases. Front Cell Neurosci (2014) 0.81
Regulating Rac in the nervous system: molecular function and disease implication of Rac GEFs and GAPs. Biomed Res Int (2015) 0.81
Nuclear envelope: positioning nuclei and organizing synapses. Curr Opin Cell Biol (2015) 0.80
Live imaging of mitosis in the developing mouse embryonic cortex. J Vis Exp (2014) 0.80
The Silencing Effect of microRNA miR-17 on p21 Maintains the Neural Progenitor Pool in the Developing Cerebral Cortex. Front Neurol (2014) 0.79
The atypical guanine nucleotide exchange factor Dock4 regulates neurite differentiation through modulation of Rac1 GTPase and actin dynamics. J Biol Chem (2013) 0.78
Regulation of cerebral cortex development by Rho GTPases: insights from in vivo studies. Front Cell Neurosci (2015) 0.78
Microtubule plus-end tracking proteins in neuronal development. Cell Mol Life Sci (2016) 0.77
MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex. Elife (2016) 0.77
Association of the variants and haplotypes in the DOCK7, PCSK9 and GALNT2 genes and the risk of hyperlipidaemia. J Cell Mol Med (2015) 0.77
Report of a patient and further clinical and molecular characterization of interstitial 4p16.3 microduplication. Mol Cytogenet (2015) 0.77
Morphological and functional aspects of progenitors perturbed in cortical malformations. Front Cell Neurosci (2015) 0.76
Protein expression profiles characterize distinct features of mouse cerebral cortices at different developmental stages. PLoS One (2015) 0.75
Regulation of neural stem cell proliferation and differentiation by Kinesin family member 2a. PLoS One (2017) 0.75
Spontaneous mutation of Dock7 results in lower trabecular bone mass and impaired periosteal expansion in aged female Misty mice. Bone (2017) 0.75
Potential mechanisms of Zika-linked microcephaly. Wiley Interdiscip Rev Dev Biol (2017) 0.75
Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases. Nat Neurosci (2004) 9.72
The cell biology of neurogenesis. Nat Rev Mol Cell Biol (2005) 9.35
Neurons derived from radial glial cells establish radial units in neocortex. Nature (2001) 7.95
Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis. Proc Natl Acad Sci U S A (2004) 4.95
Asymmetric inheritance of radial glial fibers by cortical neurons. Neuron (2001) 4.31
Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage. Development (2000) 4.14
Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells. Development (2004) 3.68
The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell (2009) 3.60
Cell-cycle control and cortical development. Nat Rev Neurosci (2007) 3.59
Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron (2004) 3.58
Neural stem cells: balancing self-renewal with differentiation. Development (2008) 3.39
Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration. Nature (2001) 3.24
LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages. J Cell Biol (2005) 3.11
Asymmetric centrosome inheritance maintains neural progenitors in the neocortex. Nature (2009) 3.03
Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient. Cell (2008) 2.97
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J Cell Sci (2002) 2.91
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nat Neurosci (2006) 2.87
Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors. Cell Stem Cell (2009) 2.81
Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis. J Comp Neurol (2008) 2.62
Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. Neuron (2007) 2.53
The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18. Neuron (2006) 2.49
Constructing the cerebral cortex: neurogenesis and fate determination. Neuron (1995) 2.46
Oblique radial glial divisions in the developing mouse neocortex induce self-renewing progenitors outside the germinal zone that resemble primate outer subventricular zone progenitors. J Neurosci (2011) 2.40
CZH proteins: a new family of Rho-GEFs. J Cell Sci (2005) 2.29
The TACC domain identifies a family of centrosomal proteins that can interact with microtubules. Proc Natl Acad Sci U S A (2000) 2.27
Mammalian Par3 regulates progenitor cell asymmetric division via notch signaling in the developing neocortex. Neuron (2009) 2.23
GSK-3 is a master regulator of neural progenitor homeostasis. Nat Neurosci (2009) 2.11
The leaving or Q fraction of the murine cerebral proliferative epithelium: a general model of neocortical neuronogenesis. J Neurosci (1996) 2.04
The TACC proteins: TACC-ling microtubule dynamics and centrosome function. Trends Cell Biol (2008) 1.85
The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. Proc Natl Acad Sci U S A (2008) 1.85
Interkinetic nuclear migration and the selection of neurogenic cell divisions during vertebrate retinogenesis. J Neurosci (2007) 1.68
Kinesin 3 and cytoplasmic dynein mediate interkinetic nuclear migration in neural stem cells. Nat Neurosci (2010) 1.66
The cell biology of neural stem and progenitor cells and its significance for their proliferation versus differentiation during mammalian brain development. Curr Opin Cell Biol (2008) 1.63
Myosin II is required for interkinetic nuclear migration of neural progenitors. Proc Natl Acad Sci U S A (2009) 1.53
Neural progenitor nuclei IN motion. Neuron (2010) 1.51
Radial glia is a progenitor of neocortical neurons in the developing cerebral cortex. Neurosci Res (2001) 1.49
Interkinetic nuclear movement may provide spatial clues to the regulation of neurogenesis. Mol Cell Neurosci (2002) 1.46
What disorders of cortical development tell us about the cortex: one plus one does not always make two. Curr Opin Genet Dev (2011) 1.45
Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain. EMBO J (2011) 1.44
Gap junctions/hemichannels modulate interkinetic nuclear migration in the forebrain precursors. J Neurosci (2010) 1.37
ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration. J Cell Biol (2008) 1.37
Centriolar satellites: busy orbits around the centrosome. Eur J Cell Biol (2011) 1.30
Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis. Neuron (2010) 1.26
Lentiviral delivery of RNAi in hippocampal neurons. Methods Enzymol (2006) 1.22
Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells. Nat Neurosci (2009) 1.19
Cellular signaling of Dock family proteins in neural function. Cell Signal (2009) 1.10
Rac is involved in the interkinetic nuclear migration of cortical progenitor cells. Neurosci Res (2009) 1.08
Loss of modifier of cell adhesion reveals a pathway leading to axonal degeneration. J Neurosci (2009) 1.06
Cell cycle control of Notch signaling and the functional regionalization of the neuroepithelium during vertebrate neurogenesis. Int J Dev Biol (2009) 1.02
Cell biological regulation of division fate in vertebrate neuroepithelial cells. Dev Dyn (2011) 1.02
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function. Proc Natl Acad Sci U S A (2009) 1.01
Mechanisms that regulate the number of neurons during mouse neocortical development. Curr Opin Neurobiol (2010) 1.01
Stem cells niches during development--lessons from the cerebral cortex. Curr Opin Neurobiol (2010) 0.98
Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell (2002) 4.50
The role of the Rho GTPases in neuronal development. Genes Dev (2005) 4.47
The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18. Neuron (2006) 2.49
The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nat Neurosci (2004) 2.26
Rho GTPases, dendritic structure, and mental retardation. J Neurobiol (2005) 2.19
Control of cell adhesion dynamics by Rap1 signaling. Curr Opin Cell Biol (2009) 1.68
Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin. Structure (2007) 1.53
The role of Rho GTPases in disease development. Gene (2002) 1.51
Importance of the Sir3 N terminus and its acetylation for yeast transcriptional silencing. Genetics (2004) 1.49
Rho-linked genes and neurological disorders. Pflugers Arch (2007) 1.39
The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. Genes Dev (2009) 1.35
The role of Rho GTPase proteins in CNS neuronal migration. Dev Neurobiol (2011) 1.28
The AF-6 homolog canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics (2003) 1.27
Role of Dok-1 and Dok-2 in leukemia suppression. J Exp Med (2004) 1.23
Lentiviral delivery of RNAi in hippocampal neurons. Methods Enzymol (2006) 1.22
Regulators of Rho GTPases in neuronal development. J Neurosci (2006) 1.11
Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins. J Biol Chem (2011) 1.10
Regulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders. J Neurosci (2010) 1.08
The Rap GTPase activator Drosophila PDZ-GEF regulates cell shape in epithelial migration and morphogenesis. Mol Cell Biol (2007) 1.06
Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Mol Cell Biol (2006) 1.05
The Rho-linked mental retardation protein OPHN1 controls synaptic vesicle endocytosis via endophilin A1. Curr Biol (2009) 1.05
Functional analysis of the protein phosphatase activity of PTEN. Biochem J (2012) 1.01
Rapid synthesis of the X-linked mental retardation protein OPHN1 mediates mGluR-dependent LTD through interaction with the endocytic machinery. Neuron (2011) 0.98
Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells. J Cell Biochem (2014) 0.90
Characterization of oligophrenin-1, a RhoGAP lost in patients affected with mental retardation: lentiviral injection in organotypic brain slice cultures. Methods Enzymol (2008) 0.89
Structural basis for allosteric stimulation of Sir2 activity by Sir4 binding. Genes Dev (2013) 0.87
Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Mol Cell Biol (2011) 0.87
WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. PLoS One (2013) 0.86
PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest (2015) 0.84
Dialogue between RhoA/ROCK and members of the Par complex in cell polarity. Dev Cell (2008) 0.81
Promoter strength influences the S phase requirement for establishment of silencing at the Saccharomyces cerevisiae silent mating type Loci. Genetics (2010) 0.80
The RASputin effect. Genes Dev (2002) 0.79
Driving actin dynamics under the influence of alcohol. Cell (2006) 0.78
DOK2 inhibits EGFR-mutated lung adenocarcinoma. PLoS One (2013) 0.78
Introduction to the ECR special issue on the roles of small GTPases. Exp Cell Res (2013) 0.75
Using cDNA-representational difference analysis (cDNA-RDA) in combination with microarrays to identify Rac regulated genes. Methods Mol Biol (2002) 0.75
Signaling mechanisms. Curr Opin Neurobiol (2010) 0.75
Signaling and gradients: what's going down? Curr Opin Cell Biol (2012) 0.75