Anterior cervical discectomy with arthroplasty versus arthrodesis for single-level cervical spondylosis: a systematic review and meta-analysis.

PubWeight™: 1.05‹?› | Rank: Top 15%

🔗 View Article (PMC 3422251)

Published in PLoS One on August 17, 2012

Authors

Aria Fallah1, Elie A Akl, Shanil Ebrahim, George M Ibrahim, Alireza Mansouri, Clary J Foote, Yuqing Zhang, Michael G Fehlings

Author Affiliations

1: Division of Neurosurgery, University of Toronto, Toronto, Canada. aria.fallah@mail.utoronto.ca

Associated clinical trials:

The Norwegian Cervical Arthroplasty Trial (NORCAT) | NCT00735176

Evaluating The Safety and Effectiveness of The NeoDisc™ Versus ACDF in Subjects With Single-Level Cervical Disc Disease (NeoDisc™) | NCT00478088

GRANVIA®-C Cervical Disc Prosthesis Multicenter European Pilot Study | NCT01518582

Arthroplasty Versus Fusion in Anterior Cervical Surgery: Prospective Study of the Impact on the Adjacent Level (PROCERV) | NCT00554528

Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study) | NCT00432159

Articles citing this

Mid- to long-term outcomes after cervical disc arthroplasty compared with anterior discectomy and fusion: a systematic review and meta-analysis of randomized controlled trials. Eur Spine J (2014) 1.11

Hybrid surgery for multilevel cervical degenerative disc diseases: a systematic review of biomechanical and clinical evidence. Eur Spine J (2014) 1.03

Construction and accuracy assessment of patient-specific biocompatible drill template for cervical anterior transpedicular screw (ATPS) insertion: an in vitro study. PLoS One (2013) 0.91

Minimally important difference estimates and methods: a protocol. BMJ Open (2015) 0.83

Magnetic resonance imaging evaluation after implantation of a titanium cervical disc prosthesis: a comparison of 1.5 and 3 Tesla magnet strength. Eur Spine J (2013) 0.83

Cervical spondylosis and hypertension: a clinical study of 2 cases. Medicine (Baltimore) (2015) 0.81

Multi-level cervical disc arthroplasty (CDA) versus single-level CDA for the treatment of cervical disc diseases: a meta-analysis. Eur Spine J (2014) 0.81

Cost Utility Analysis of the Cervical Artificial Disc vs Fusion for the Treatment of 2-Level Symptomatic Degenerative Disc Disease: 5-Year Follow-up. Neurosurgery (2016) 0.79

Quality of systematic reviews: an example of studies comparing artificial disc replacement with fusion in the cervical spine. Libyan J Med (2015) 0.79

Hybrid Surgery Versus Anterior Cervical Discectomy and Fusion in Multilevel Cervical Disc Diseases: A Meta-Analysis. Medicine (Baltimore) (2016) 0.78

CT morphometric analysis to determine the anatomical basis for the use of transpedicular screws during reconstruction and fixations of anterior cervical vertebrae. PLoS One (2013) 0.78

PEEK cages versus PMMA spacers in anterior cervical discectomy: comparison of fusion, subsidence, sagittal alignment, and clinical outcome with a minimum 1-year follow-up. ScientificWorldJournal (2014) 0.78

Cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF) in symptomatic cervical degenerative disc diseases (CDDDs): an updated meta-analysis of prospective randomized controlled trials (RCTs). Springerplus (2016) 0.77

Comparison of 2 Zero-Profile Implants in the Treatment of Single-Level Cervical Spondylotic Myelopathy: A Preliminary Clinical Study of Cervical Disc Arthroplasty versus Fusion. PLoS One (2016) 0.77

Anterior cervical discectomy and fusion versus anterior cervical corpectomy and fusion in multilevel cervical spondylotic myelopathy: A meta-analysis. Medicine (Baltimore) (2016) 0.75

Anterior cervical disc arthroplasty (ACDA) versus anterior cervical discectomy and fusion (ACDF): a systematic review and meta-analysis. J Spine Surg (2015) 0.75

Reoperations Following Cervical Disc Replacement. Asian Spine J (2015) 0.75

Cervical disc replacement - emerging equivalency to anterior cervical discectomy and fusion. Int Orthop (2016) 0.75

Articles cited by this

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol (2009) 17.92

Language bias in randomised controlled trials published in English and German. Lancet (1997) 7.29

GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology. J Clin Epidemiol (2010) 5.78

Clinical and radiographic analysis of cervical disc arthroplasty compared with allograft fusion: a randomized controlled clinical trial. J Neurosurg Spine (2007) 5.27

Association between industry funding and statistically significant pro-industry findings in medical and surgical randomized trials. CMAJ (2004) 4.53

Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervical disc disease. Spine J (2008) 4.44

Long-term clinical and radiographic outcomes of cervical disc replacement with the Prestige disc: results from a prospective randomized controlled clinical trial. J Neurosurg Spine (2010) 4.28

Comparison of BRYAN cervical disc arthroplasty with anterior cervical decompression and fusion: clinical and radiographic results of a randomized, controlled, clinical trial. Spine (Phila Pa 1976) (2009) 3.18

Specific instructions for estimating unclearly reported blinding status in randomized trials were reliable and valid. J Clin Epidemiol (2011) 2.69

Prospective, randomized, multicenter study of cervical arthroplasty: 269 patients from the Kineflex|C artificial disc investigational device exemption study with a minimum 2-year follow-up: clinical article. J Neurosurg Spine (2011) 2.58

Artificial disc versus fusion: a prospective, randomized study with 2-year follow-up on 99 patients. Spine (Phila Pa 1976) (2007) 2.55

Results of cervical arthroplasty compared with anterior discectomy and fusion: four-year clinical outcomes in a prospective, randomized controlled trial. J Bone Joint Surg Am (2011) 2.52

Assessment of adjacent-segment disease in patients treated with cervical fusion or arthroplasty: a prospective 2-year study. J Neurosurg Spine (2005) 2.52

Neck Disability Index, short form-36 physical component summary, and pain scales for neck and arm pain: the minimum clinically important difference and substantial clinical benefit after cervical spine fusion. Spine J (2010) 1.94

Clinical practice. Cervical radiculopathy. N Engl J Med (2005) 1.91

Analysis of the three United States Food and Drug Administration investigational device exemption cervical arthroplasty trials. J Neurosurg Spine (2011) 1.75

No justification for cervical disk prostheses in clinical practice: a meta-analysis of randomized controlled trials. Neurosurgery (2010) 1.73

Cervical disc arthroplasty versus fusion for single-level symptomatic cervical disc disease: a meta-analysis of randomized controlled trials. Arch Orthop Trauma Surg (2011) 1.59

Disc replacement using Pro-Disc C versus fusion: a prospective randomised and controlled radiographic and clinical study. Eur Spine J (2006) 1.51

Clinical outcomes of Bryan cervical disc arthroplasty a prospective, randomized, controlled, single site trial with 48-month follow-up. J Spinal Disord Tech (2010) 1.48

Changes in segmental intervertebral motion adjacent to cervical arthrodesis: a prospective study. Spine (Phila Pa 1976) (2004) 1.38

Clinical outcomes of BRYAN cervical disc arthroplasty: a prospective, randomized, controlled, multicenter trial with 24-month follow-up. J Spinal Disord Tech (2007) 1.36

The ProDisc-C prosthesis: clinical and radiological experience 1 year after surgery. Spine (Phila Pa 1976) (2007) 1.29

Total disc arthroplasty does not affect the incidence of adjacent segment degeneration in cervical spine: results of 93 patients in three prospective randomized clinical trials. Spine J (2010) 1.28

Comparison of adverse events between the Bryan artificial cervical disc and anterior cervical arthrodesis. Spine (Phila Pa 1976) (2008) 1.27

Reliability, construct validity, and responsiveness of the neck disability index, patient-specific functional scale, and numeric pain rating scale in patients with cervical radiculopathy. Am J Phys Med Rehabil (2010) 1.23

Lower incidence of dysphagia with cervical arthroplasty compared with ACDF in a prospective randomized clinical trial. J Spinal Disord Tech (2010) 1.16

Clinical outcomes with the Prestige II cervical disc: preliminary results from a prospective randomized clinical trial. Neurosurg Focus (2004) 1.15

Prospective study of cervical arthroplasty in 98 patients involved in 1 of 3 separate investigational device exemption studies from a single investigational site with a minimum 2-year follow-up. Clinical article. J Neurosurg Spine (2010) 1.12

Index and adjacent level kinematics after cervical disc replacement and anterior fusion: in vivo quantitative radiographic analysis. Spine (Phila Pa 1976) (2011) 1.12

Cervical disc prosthesis replacement and interbody fusion: a comparative study. Int Orthop (2006) 1.09

Sagittal cervical alignment after cervical disc arthroplasty and anterior cervical discectomy and fusion: results of a prospective, randomized, controlled trial. Spine (Phila Pa 1976) (2009) 1.09

Prospective randomized controlled study of the Bryan Cervical Disc: early clinical results from a single investigational site. J Neurosurg Spine (2006) 1.06

Segmental kinematics and adjacent level degeneration following disc replacement versus fusion: RCT with three years of follow-up. J Long Term Eff Med Implants (2007) 1.06

Segmental contribution toward total cervical range of motion: a comparison of cervical disc arthroplasty and fusion. Spine (Phila Pa 1976) (2011) 1.04

Prevalence of heterotopic ossification after cervical total disc arthroplasty: a meta-analysis. Eur Spine J (2011) 1.04

Multi-center, prospective, randomized, controlled investigational device exemption clinical trial comparing Mobi-C Cervical Artificial Disc to anterior discectomy and fusion in the treatment of symptomatic degenerative disc disease in the cervical spine. Int J Spine Surg (2014) 1.03

Results at 24 months from the prospective, randomized, multicenter Investigational Device Exemption trial of ProDisc-C versus anterior cervical discectomy and fusion with 4-year follow-up and continued access patients. SAS J (2010) 1.02

A systematic review of randomized trials on the effect of cervical disc arthroplasty on reducing adjacent-level degeneration. Neurosurg Focus (2010) 1.02

Motion analysis of bryan cervical disc arthroplasty versus anterior discectomy and fusion: results from a prospective, randomized, multicenter, clinical trial. J Spinal Disord Tech (2008) 1.01

Assessment of adjacent-segment mobility after cervical disc replacement versus fusion: RCT with 1 year's results. Eur Spine J (2011) 0.99

Cervical disc arthroplasty: a controlled randomized prospective study with intermediate follow-up results. Invited submission from the joint section meeting on disorders of the spine and peripheral nerves, March 2005. J Neurosurg Spine (2005) 0.92

Systematic review and meta-analysis of randomized controlled trials: comparison of total disk replacement with anterior cervical decompression and fusion. Orthopedics (2011) 0.91

[Clinical outcomes of single level Bryan cervical disc arthroplasty: a prospective controlled study]. Zhonghua Wai Ke Za Zhi (2008) 0.90

Comparison of short-term SF-36 results between total joint arthroplasty and cervical spine decompression and fusion or arthroplasty. Spine (Phila Pa 1976) (2009) 0.88

Comparison of single-level cervical fusion and a metal-on-metal cervical disc replacement device. Am J Orthop (Belle Mead NJ) (2008) 0.86

Effect of modified techniques in Bryan cervical disc arthroplasty. Spine (Phila Pa 1976) (2009) 0.84

Sagittal alignment after Bryan cervical arthroplasty. Spine (Phila Pa 1976) (2011) 0.82

Re: McAfee PC, Reah C, Gilder K, et al. A meta-analysis of comparative outcomes following cervical arthroplasty or anterior cervical fusion: results from four prospective multi-center randomized clinical trials and up to 1226 patients. Spine (Phila Pa 1976) 2012;37:943–52. Spine (Phila Pa 1976) (2012) 0.79

Articles by these authors

GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol (2010) 11.77

Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 10.75

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis. JAMA (2010) 5.90

Executive summary: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 5.88

GRADE guidelines: 4. Rating the quality of evidence--study limitations (risk of bias). J Clin Epidemiol (2011) 5.10

Prevention of VTE in nonsurgical patients: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 5.02

European Society of Hypertension position paper on ambulatory blood pressure monitoring. J Hypertens (2013) 4.28

Association between radiographic features of knee osteoarthritis and pain: results from two cohort studies. BMJ (2009) 3.99

Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or =60 y. Am J Clin Nutr (2004) 3.76

A new classification of thoracolumbar injuries: the importance of injury morphology, the integrity of the posterior ligamentous complex, and neurologic status. Spine (Phila Pa 1976) (2005) 3.68

Increasing prevalence of knee pain and symptomatic knee osteoarthritis: survey and cohort data. Ann Intern Med (2011) 3.65

GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations. J Clin Epidemiol (2013) 3.58

The vexing problem of guidelines and conflict of interest: a potential solution. Ann Intern Med (2010) 3.47

Comparative efficacy, acceptability, and tolerability of augmentation agents in treatment-resistant depression: systematic review and network meta-analysis. J Clin Psychiatry (2015) 3.46

GRADE guidelines: 5. Rating the quality of evidence--publication bias. J Clin Epidemiol (2011) 3.44

Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis. BMJ (2009) 3.39

GRADE guidelines: 9. Rating up the quality of evidence. J Clin Epidemiol (2011) 3.30

The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients. J Hypertens (2005) 3.27

Validity of composite end points in clinical trials. BMJ (2005) 3.26

Methodology for the development of antithrombotic therapy and prevention of thrombosis guidelines: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 3.14

Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled trials. BMJ (2007) 3.06

Antivirals for treatment of influenza: a systematic review and meta-analysis of observational studies. Ann Intern Med (2012) 3.05

GRADE guidelines: 7. Rating the quality of evidence--inconsistency. J Clin Epidemiol (2011) 3.02

Oral direct Factor Xa inhibitors versus low-molecular-weight heparin to prevent venous thromboembolism in patients undergoing total hip or knee replacement: a systematic review and meta-analysis. Ann Intern Med (2012) 2.91

GRADE guidelines: 8. Rating the quality of evidence--indirectness. J Clin Epidemiol (2011) 2.83

Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis. Arthritis Rheum (2006) 2.81

Self-assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injury. J Neurosci (2008) 2.79

Risk for cardiovascular disease early and late after a diagnosis of giant-cell arteritis: a cohort study. Ann Intern Med (2014) 2.76

Credibility of claims of subgroup effects in randomised controlled trials: systematic review. BMJ (2012) 2.69

A new approach yields high rates of radiographic progression in knee osteoarthritis. J Rheumatol (2008) 2.63

The effect of body weight on progression of knee osteoarthritis is dependent on alignment. Arthritis Rheum (2004) 2.58

Antithrombotic and thrombolytic therapy for ischemic stroke: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 2.55

Primary and secondary prevention of cardiovascular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 2.50

The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration. J Neurotrauma (2004) 2.48

Vertebral compression fracture (VCF) after spine stereotactic body radiation therapy (SBRT): analysis of predictive factors. Int J Radiat Oncol Biol Phys (2012) 2.45

Surgical management of tethered cord syndrome in adults: indications, techniques, and long-term outcomes in 60 patients. J Neurosurg Spine (2006) 2.43

Antihypertensive drugs and risk of incident gout among patients with hypertension: population based case-control study. BMJ (2012) 2.39

Current status of acute spinal cord injury pathophysiology and emerging therapies: promise on the horizon. Neurosurg Focus (2008) 2.37

Reliability of the spinal instability neoplastic scale among radiologists: an assessment of instability secondary to spinal metastases. AJR Am J Roentgenol (2014) 2.28

Increasing incidence of shoulder arthroplasty in the United States. J Bone Joint Surg Am (2011) 2.15

Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. J Neurosci (2006) 2.13

Effect of recreational physical activities on the development of knee osteoarthritis in older adults of different weights: the Framingham Study. Arthritis Rheum (2007) 2.12

Ethics and legalities associated with independent medical evaluations. CMAJ (2014) 2.11

Knee alignment does not predict incident osteoarthritis: the Framingham osteoarthritis study. Arthritis Rheum (2007) 2.11

Toward the Development of a Universal Outcome Instrument for Spine Trauma: A Systematic Review and Content Comparison of Outcome Measures Used in Spine Trauma Research Using the ICF as Reference. Spine (Phila Pa 1976) (2016) 2.05

Comparative effectiveness of surgical versus nonoperative management of unilateral, nondisplaced, subaxial cervical spine facet fractures without evidence of spinal cord injury: clinical article. J Neurosurg Spine (2014) 1.97

The Longitudinal Examination of Arthritis Pain (LEAP) study: relationships between weekly fluctuations in patient-rated joint pain and other health outcomes. J Rheumatol (2007) 1.95

Tibiofemoral joint osteoarthritis: risk factors for MR-depicted fast cartilage loss over a 30-month period in the multicenter osteoarthritis study. Radiology (2009) 1.95

A systematic review of cellular transplantation therapies for spinal cord injury. J Neurotrauma (2010) 1.95

Proposal of a modified, treatment-oriented classification of odontoid fractures. Spine J (2005) 1.94

Frequency and predictors of inappropriate management of recurrent gout attacks in a longitudinal study. J Rheumatol (2005) 1.93

Structural factors associated with malalignment in knee osteoarthritis: the Boston osteoarthritis knee study. J Rheumatol (2005) 1.93

A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group. Spine (Phila Pa 1976) (2010) 1.91

Clinical practice. Cervical radiculopathy. N Engl J Med (2005) 1.91

GRADE guidelines: 11. Making an overall rating of confidence in effect estimates for a single outcome and for all outcomes. J Clin Epidemiol (2012) 1.90

Intraoperative adverse events and related postoperative complications in spine surgery: implications for enhancing patient safety founded on evidence-based protocols. Spine (Phila Pa 1976) (2006) 1.89

Spinal cord injury: time to move? J Neurosci (2007) 1.87

Injury of the posterior ligamentous complex of the thoracolumbar spine: a prospective evaluation of the diagnostic accuracy of magnetic resonance imaging. Spine (Phila Pa 1976) (2009) 1.86

Guidelines 2.0: systematic development of a comprehensive checklist for a successful guideline enterprise. CMAJ (2013) 1.86

GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes. J Clin Epidemiol (2012) 1.86

Patient values and preferences in decision making for antithrombotic therapy: a systematic review: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 1.85

Randomisation to protect against selection bias in healthcare trials. Cochrane Database Syst Rev (2011) 1.82

The thoracolumbar injury severity score: a proposed treatment algorithm. J Spinal Disord Tech (2005) 1.82

Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression. Proc Natl Acad Sci U S A (2007) 1.81

Acute cervical traumatic spinal cord injury: MR imaging findings correlated with neurologic outcome--prospective study with 100 consecutive patients. Radiology (2007) 1.81

Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice. Brain (2003) 1.81

Recent diuretic use and the risk of recurrent gout attacks: the online case-crossover gout study. J Rheumatol (2006) 1.79

The surgical approach to subaxial cervical spine injuries: an evidence-based algorithm based on the SLIC classification system. Spine (Phila Pa 1976) (2007) 1.78

Pharmacological approaches to repair the injured spinal cord. J Neurotrauma (2006) 1.77

Myelination of congenitally dysmyelinated spinal cord axons by adult neural precursor cells results in formation of nodes of Ranvier and improved axonal conduction. J Neurosci (2007) 1.74

Incidence and prevalence of spinal cord injury in Canada: a national perspective. Neuroepidemiology (2012) 1.74

Surgical management of cervical degenerative disease: the evidence related to indications, impact, and outcome. J Neurosurg Spine (2009) 1.72

A case-control study of oral contraceptive use and incident breast cancer. Am J Epidemiol (2008) 1.72

Spinal instability neoplastic score: an analysis of reliability and validity from the spine oncology study group. J Clin Oncol (2011) 1.69

Interpreting the results of patient reported outcome measures in clinical trials: the clinician's perspective. Health Qual Life Outcomes (2006) 1.64

Bone marrow lesions in the knee are associated with increased local bone density. Arthritis Rheum (2005) 1.64

Blood pressure reduction for the secondary prevention of stroke: a Chinese trial and a systematic review of the literature. Hypertens Res (2009) 1.63

Obesity and the risk of psoriatic arthritis: a population-based study. Ann Rheum Dis (2012) 1.63

Presence of MRI-detected joint effusion and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30-month follow-up: the MOST study. Ann Rheum Dis (2011) 1.63

Introduction to the ninth edition: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest (2012) 1.63

Incretin treatment and risk of pancreatitis in patients with type 2 diabetes mellitus: systematic review and meta-analysis of randomised and non-randomised studies. BMJ (2014) 1.63

Autonomic dysreflexia in acute spinal cord injury: an under-recognized clinical entity. J Neurotrauma (2003) 1.63

Ischemic insults direct glutamate receptor subunit 2-lacking AMPA receptors to synaptic sites. J Neurosci (2006) 1.63

Guidance for evidence-informed policies about health systems: assessing how much confidence to place in the research evidence. PLoS Med (2012) 1.62

Hypothermia for spinal cord injury. Spine J (2008) 1.61

Epidemiology of osteoarthritis. Rheum Dis Clin North Am (2012) 1.61

Radiation-induced vertebral compression fracture following spine stereotactic radiosurgery: clinicopathological correlation. J Neurosurg Spine (2013) 1.61

MicroRNA-196: critical roles and clinical applications in development and cancer. J Cell Mol Med (2011) 1.59

Pregnancy outcomes in women with chronic kidney disease: a systematic review. Clin J Am Soc Nephrol (2011) 1.59

Os odontoideum: etiology and surgical management. Neurosurgery (2010) 1.59

Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord. J Neurosci (2010) 1.59

European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring. J Hypertens (2014) 1.58

Pathophysiology of cervical myelopathy. Spine J (2006) 1.56

Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury. Neurosurg Focus (2008) 1.56

Timing of decompressive surgery of spinal cord after traumatic spinal cord injury: an evidence-based examination of pre-clinical and clinical studies. J Neurotrauma (2010) 1.54

A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury. J Neurotrauma (2010) 1.54

Diagnosis and management of metastatic spine disease. A review. J Neurosurg Spine (2010) 1.52

Cardiovascular complications after acute spinal cord injury: pathophysiology, diagnosis, and management. Neurosurg Focus (2008) 1.51

Effect of birth cohort on risk of hip fracture: age-specific incidence rates in the Framingham Study. Am J Public Health (2002) 1.50