Published in Gastroenterology on August 21, 2012
Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat Commun (2013) 4.22
Hippo pathway activity influences liver cell fate. Cell (2014) 2.24
Extensive conversion of hepatic biliary epithelial cells to hepatocytes after near total loss of hepatocytes in zebrafish. Gastroenterology (2013) 2.14
Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer. Cell (2015) 1.89
Adult hepatocytes are generated by self-duplication rather than stem cell differentiation. Cell Stem Cell (2014) 1.88
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Bipotential adult liver progenitors are derived from chronically injured mature hepatocytes. Cell Stem Cell (2014) 1.61
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Progenitor cell expansion and impaired hepatocyte regeneration in explanted livers from alcoholic hepatitis. Gut (2015) 1.54
Hepatic progenitor cells of biliary origin with liver repopulation capacity. Nat Cell Biol (2015) 1.45
Emerging roles of Notch signaling in liver disease. Hepatology (2014) 1.39
Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury. Hepatology (2014) 1.32
Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy. Gut (2013) 1.26
Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling. Proc Natl Acad Sci U S A (2013) 1.20
The biliary epithelium gives rise to liver progenitor cells. Hepatology (2014) 1.19
Utility of osteopontin in lineage tracing experiments. Gastroenterology (2013) 1.13
FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev (2013) 1.05
Combined hepatocellular-cholangiocarcinoma with stem cell features, ductal plate malformation subtype: a case report and proposal of a new subtype. Int J Clin Exp Pathol (2013) 1.05
Osteopontin neutralisation abrogates the liver progenitor cell response and fibrogenesis in mice. Gut (2014) 1.03
Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers. EMBO J (2014) 1.03
Sry HMG box protein 9-positive (Sox9+) epithelial cell adhesion molecule-negative (EpCAM-) biphenotypic cells derived from hepatocytes are involved in mouse liver regeneration. J Biol Chem (2014) 1.02
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Differentiation of progenitors in the liver: a matter of local choice. J Clin Invest (2013) 1.00
Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury. Hepatology (2014) 0.99
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Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J Clin Invest (2015) 0.95
The origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells. Curr Top Dev Biol (2014) 0.93
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Stem cells versus plasticity in liver and pancreas regeneration. Nat Cell Biol (2016) 0.92
The roles of transforming growth factor-β, Wnt, Notch and hypoxia on liver progenitor cells in primary liver tumours (Review). Int J Oncol (2014) 0.88
Ablation of Foxl1-Cre-labeled hepatic progenitor cells and their descendants impairs recovery of mice from liver injury. Gastroenterology (2014) 0.88
Liver repopulation and regeneration: new approaches to old questions. Curr Opin Organ Transplant (2013) 0.85
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Nuclear double-fluorescent reporter for in vivo and ex vivo analyses of biological transitions in mouse nuclei. Mamm Genome (2013) 0.85
Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling. Genes Dev (2013) 0.84
Fibroblast growth factor signaling regulates the expansion of A6-expressing hepatocytes in association with AKT-dependent β-catenin activation. J Hepatol (2013) 0.83
Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids. Stem Cell Reports (2015) 0.81
The plastic liver: differentiated cells, stem cells, every cell? J Clin Invest (2014) 0.81
Modeling human liver biology using stem cell-derived hepatocytes. Int J Mol Sci (2013) 0.80
Pancreatic duct glands (PDGs) are a progenitor compartment responsible for pancreatic ductal epithelial repair. Stem Cell Res (2015) 0.80
Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration. J Hepatol (2015) 0.79
Rat liver regeneration following ablation with irreversible electroporation. PeerJ (2016) 0.79
Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration. Stem Cells Int (2016) 0.79
The plastic cellular states of liver cells: Are EpCAM and Lgr5 fit for purpose? Hepatology (2016) 0.78
Hepatic progenitor cells in canine and feline medicine: potential for regenerative strategies. BMC Vet Res (2014) 0.78
A modified choline-deficient, ethionine-supplemented diet reduces morbidity and retains a liver progenitor cell response in mice. Dis Model Mech (2015) 0.78
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Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis Tissue Repair (2015) 0.78
Myofibroblasts Derived from Hepatic Progenitor Cells Create the Tumor Microenvironment. Stem Cell Reports (2016) 0.77
Cell turnover in the repopulated rat liver: distinct lineages for hepatocytes and the biliary epithelium. Cell Tissue Res (2014) 0.77
Advances in hepatic stem/progenitor cell biology. EXCLI J (2015) 0.77
Repair of liver mediated by adult mouse liver neuro-glia antigen 2-positive progenitor cell transplantation in a mouse model of cirrhosis. Sci Rep (2016) 0.77
Adult Hepatic Progenitor Cell Niche: How it affects the Progenitor Cell Fate. Middle East J Dig Dis (2014) 0.77
A disintegrin and metalloprotease with thrombospondin type I motif 7: a new protease for connective tissue growth factor in hepatic progenitor/oval cell niche. Am J Pathol (2015) 0.77
MBSJ MCC Young Scientist Award 2012 Liver regeneration: a unique and flexible reaction depending on the type of injury. Genes Cells (2014) 0.76
Activin A-Smad Signaling Mediates Connective Tissue Growth Factor Synthesis in Liver Progenitor Cells. Int J Mol Sci (2016) 0.76
Cellular plasticity in the adult liver and stomach. J Physiol (2016) 0.76
Role of Osteopontin in Liver Diseases. Int J Biol Sci (2016) 0.76
Genetic lineage tracing analysis of the cell of origin of hepatotoxin-induced liver tumors in mice. Hepatology (2016) 0.76
Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells. Cell Rep (2017) 0.76
Immunohistochemical Analysis of the Stem Cell Marker LGR5 in Pediatric Liver Disease. Pediatr Dev Pathol (2017) 0.75
Environmental Ligands of the Aryl Hydrocarbon Receptor and Their Effects in Models of Adult Liver Progenitor Cells. Stem Cells Int (2016) 0.75
Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice. Sci Rep (2016) 0.75
A Transcriptomic Signature of Mouse Liver Progenitor Cells. Stem Cells Int (2016) 0.75
Pigment epithelium-derived factor (PEDF) peptide promotes the expansion of hepatic stem/progenitor cells via ERK and STAT3-dependent signaling. Am J Transl Res (2017) 0.75
A label-retaining but unipotent cell population resides in biliary compartment of mammalian liver. Sci Rep (2017) 0.75
Inflammation Shapes Stem Cells and Stemness during Infection and Beyond. Front Cell Dev Biol (2016) 0.75
Experimental Model for Successful Liver Cell Therapy by Lenti TTR-YapERT2 Transduced Hepatocytes with Tamoxifen Control of Yap Subcellular Location. Sci Rep (2016) 0.75
Progressive induction of hepatocyte progenitor cells in chronically injured liver. Sci Rep (2017) 0.75
Liver-derived human mesenchymal stem cells: a novel therapeutic source for liver diseases. Stem Cell Res Ther (2016) 0.75
Imatinib accelerates progenitor cell-mediated liver regeneration in choline-deficient ethionine-supplemented diet-fed mice. Int J Exp Pathol (2016) 0.75
Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease. PLoS One (2017) 0.75
Next generation of ALDH substrates and their potential to study maturational lineage biology in stem and progenitor cells. Am J Physiol Gastrointest Liver Physiol (2015) 0.75
Lipopolysaccharide induces the differentiation of hepatic progenitor cells into myofibroblasts via activation of the Hedgehog signalling pathway. Cell Cycle (2017) 0.75
Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes. Stem Cell Reports (2017) 0.75
The diversity and plasticity of adult hepatic progenitor cells and their niche. Liver Int (2017) 0.75
Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation. Stem Cell Res Ther (2017) 0.75
Y-box Protein-1 Regulates the Expression of Collagen I in Hepatic Progenitor Cells via PDGFR-β/ERK/p90RSK Signalling. Stem Cells Int (2017) 0.75
Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria. Am J Hum Genet (2004) 4.08
Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology (2011) 3.19
Expression of miR-33 from an SREBP2 intron inhibits cholesterol export and fatty acid oxidation. J Biol Chem (2010) 2.99
Identification of the cell lineage at the origin of basal cell carcinoma. Nat Cell Biol (2010) 2.97
The onecut transcription factor HNF6 is required for normal development of the biliary tract. Development (2002) 2.89
Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology (2009) 2.33
MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells. J Biol Chem (2006) 2.29
Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J Cell Biol (2009) 2.24
Identifying the cellular origin of squamous skin tumors. Proc Natl Acad Sci U S A (2011) 2.24
Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury. Hepatology (2009) 2.23
The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology (2006) 2.10
Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. Genes Dev (2005) 2.02
Multipotent and unipotent progenitors contribute to prostate postnatal development. Nat Cell Biol (2012) 1.89
Kupffer cell activation is a causal factor for hepatic insulin resistance. Am J Physiol Gastrointest Liver Physiol (2009) 1.85
A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesis. Hepatology (2011) 1.84
Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences. J Hepatol (2007) 1.75
Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation. Genome Res (2010) 1.67
Biliary differentiation and bile duct morphogenesis in development and disease. Int J Biochem Cell Biol (2009) 1.47
A feedback loop between the liver-enriched transcription factor network and miR-122 controls hepatocyte differentiation. Gastroenterology (2011) 1.44
Attenuation of the effect of the FTO rs9939609 polymorphism on total and central body fat by physical activity in adolescents: the HELENA study. Arch Pediatr Adolesc Med (2010) 1.35
The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration. Dev Biol (2007) 1.20
Sterol regulatory element binding protein-1c expression and action in rat muscles: insulin-like effects on the control of glycolytic and lipogenic enzymes and UCP3 gene expression. Diabetes (2002) 1.17
Expression of the alpha7 isoform of hepatocyte nuclear factor (HNF) 4 is activated by HNF6/OC-2 and HNF1 and repressed by HNF4alpha1 in the liver. J Biol Chem (2004) 1.14
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia. Gut (2012) 1.14
A vHNF1/TCF2-HNF6 cascade regulates the transcription factor network that controls generation of pancreatic precursor cells. Diabetes (2006) 1.13
Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1. BMC Dev Biol (2009) 1.09
Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1. Nucleic Acids Res (2006) 1.08
Kupffer cell depletion prevents but has no therapeutic effect on metabolic and inflammatory changes induced by a high-fat diet. FASEB J (2011) 1.04
Epithelial: Endothelial cross-talk regulates exocrine differentiation in developing pancreas. Dev Biol (2010) 1.04
Why and How Meet n-3 PUFA Dietary Recommendations? Gastroenterol Res Pract (2010) 1.04
Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study. J Alzheimers Dis (2010) 1.03
Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets. PLoS One (2011) 1.03
Successful isolation of liver progenitor cells by aldehyde dehydrogenase activity in naïve mice. Hepatology (2012) 1.02
Phosphoserine aminotransferase deficiency: a novel disorder of the serine biosynthesis pathway. Am J Hum Genet (2007) 1.00
The metabolic syndrome: how it may influence hepatic stellate cell activation and hepatic fibrosis. Curr Opin Clin Nutr Metab Care (2009) 0.99
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment. J Clin Invest (2015) 0.95
Single-nucleotide polymorphism of CD36 locus and obesity in European adolescents. Obesity (Silver Spring) (2009) 0.95
NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis. J Hepatol (2006) 0.93
MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2. Biochem Biophys Res Commun (2009) 0.93
Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6. Gastroenterology (2013) 0.92
The transcription factor hepatocyte nuclear factor-6/Onecut-1 controls the expression of its paralog Onecut-3 in developing mouse endoderm. J Biol Chem (2004) 0.92
Increased protein glycation in fructosamine 3-kinase-deficient mice. Biochem J (2006) 0.91
Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment. Development (2014) 0.91
Gene transfer into mouse prepancreatic endoderm by whole embryo electroporation. JOP (2005) 0.90
The nuclear orphan receptor Nur77 is a lipotoxicity sensor regulating glucose-induced insulin secretion in pancreatic β-cells. Mol Endocrinol (2012) 0.90
Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation. Dev Biol (2007) 0.90
Distribution of human beta-defensin polymorphisms in various control and cystic fibrosis populations. Genomics (2005) 0.89
Role of vascular endothelial growth factor in the pathophysiology of nonalcoholic steatohepatitis in two rodent models. Hepatology (2013) 0.89
Prevention of steatohepatitis by pioglitazone: implication of adiponectin-dependent inhibition of SREBP-1c and inflammation. J Hepatol (2008) 0.88
Peroxisome proliferated-activated receptor gamma ligand, Pioglitazone, does not prevent hepatic fibrosis in mice. Int J Mol Med (2007) 0.86
Participation of liver progenitor cells in liver regeneration: lack of evidence in the AAF/PH rat model. Lab Invest (2011) 0.84
OC-3, a novel mammalian member of the ONECUT class of transcription factors. Biochem Biophys Res Commun (2002) 0.83
Suggestive evidence of associations between liver X receptor β polymorphisms with type 2 diabetes mellitus and obesity in three cohort studies: HUNT2 (Norway), MONICA (France) and HELENA (Europe). BMC Med Genet (2010) 0.82
HNF1B deficiency causes ciliary defects in human cholangiocytes. Hepatology (2012) 0.82
Transcriptional mechanisms of EphA7 gene expression in the developing cerebral cortex. Cereb Cortex (2011) 0.81
Liver and systemic insulin resistance. Hepatology (2014) 0.81
Clodronate liposomes: all sites of injection are not equal. Hepatology (2010) 0.80
Prometheus' little helper, a novel role for fibroblast growth factor 15 in compensatory liver growth. J Hepatol (2013) 0.80
Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats. Chem Biol Interact (2010) 0.80
Impact of PPAR-α induction on glucose homoeostasis in alcohol-fed mice. Clin Sci (Lond) (2013) 0.79
The genetic programme of pancreatic beta-cells: basic science for the development of beta-cell therapy. Workshop on programming pancreatic beta-cells. EMBO Rep (2007) 0.79
Influence of surface charge and inner composition of nanoparticles on intracellular delivery of proteins in airway epithelial cells. Biomaterials (2012) 0.78
Maged1, a new regulator of skeletal myogenic differentiation and muscle regeneration. BMC Cell Biol (2010) 0.78
Mutations in phenotypically mild D-2-hydroxyglutaric aciduria. Ann Neurol (2005) 0.78
Reply: To PMID 22922013. Gastroenterology (2013) 0.78
Hepatic Stellate Cells Improve Engraftment of Human Primary Hepatocytes: A Preclinical Transplantation Study in an Animal Model. Cell Transplant (2015) 0.78
Study of the genetic variability of ZAC1 (PLAGL1) in French population-based samples. J Hypertens (2009) 0.77
Development of hepatic fibrosis occurs normally in AMPK-deficient mice. Clin Sci (Lond) (2009) 0.76
Yin Yang 1 and farnesoid X receptor: a balancing act in non-alcoholic fatty liver disease? Gut (2013) 0.75
Pro-oxidants or anti-oxidant defenses? Which one to blame in non-alcoholic steatohepatitis pathogenesis? J Gastroenterol Hepatol (2012) 0.75
Adiponectin in non-alcoholic steatohepatitis: an ideal culprit, but what are the proofs of its guilt? J Gastroenterol Hepatol (2009) 0.75
Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis. Development (2016) 0.75
Association between a thyroid hormone receptor-α gene polymorphism and blood pressure but not with coronary heart disease risk. Am J Hypertens (2011) 0.75
Inhibition of early preneoplastic events in the rat liver by the somatostatin analog lanreotide. Cancer Sci (2007) 0.75