Imaging enzyme-triggered self-assembly of small molecules inside live cells.

D-amino acids boost the selectivity and confer supramolecular hydrogels of a nonsteroidal anti-inflammatory drug (NSAID). J Am Chem Soc (2012) 1.25

Dephosphorylation of D-peptide derivatives to form biofunctional, supramolecular nanofibers/hydrogels and their potential applications for intracellular imaging and intratumoral chemotherapy. J Am Chem Soc (2013) 1.20

Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials. Chem Rev (2015) 1.03

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo. Nat Chem (2014) 0.98

Prion-like nanofibrils of small molecules (PriSM) selectively inhibit cancer cells by impeding cytoskeleton dynamics. J Biol Chem (2014) 0.96

Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics. ACS Nano (2015) 0.95

Caspase-responsive smart gadolinium-based contrast agent for magnetic resonance imaging of drug-induced apoptosis. Chem Sci (2014) 0.90

Enzyme-Instructed Intracellular Molecular Self-Assembly to Boost Activity of Cisplatin against Drug-Resistant Ovarian Cancer Cells. Angew Chem Int Ed Engl (2015) 0.90

Ligand-receptor interaction catalyzes the aggregation of small molecules to induce cell necroptosis. J Am Chem Soc (2014) 0.88

In vivo covalent cross-linking of photon-converted rare-earth nanostructures for tumour localization and theranostics. Nat Commun (2016) 0.87

Probing nanoscale self-assembly of nonfluorescent small molecules inside live mammalian cells. ACS Nano (2013) 0.87

Taurine Boosts Cellular Uptake of Small D-Peptides for Enzyme-Instructed Intracellular Molecular Self-Assembly. J Am Chem Soc (2015) 0.85

A redox responsive, fluorescent supramolecular metallohydrogel consists of nanofibers with single-molecule width. J Am Chem Soc (2013) 0.85

Imaging self-assembly dependent spatial distribution of small molecules in a cellular environment. Langmuir (2013) 0.85

Enzyme-Instructed Self-Assembly of Small d-Peptides as a Multiple-Step Process for Selectively Killing Cancer Cells. J Am Chem Soc (2016) 0.85

Supramolecular hydrogels made of basic biological building blocks. Chem Asian J (2014) 0.83

Nanoscale Assemblies of Small Molecules Control the Fate of Cells. Nano Today (2015) 0.81

Enhanced cellular entry and efficacy of tat conjugates by rational design of the auxiliary segment. Mol Pharm (2014) 0.81

Biocompatible fluorescent supramolecular nanofibrous hydrogel for long-term cell tracking and tumor imaging applications. Sci Rep (2015) 0.79

Cooperative self-assembly of peptide gelators and proteins. Biomacromolecules (2013) 0.78

Enzyme transformation to modulate the ligand-receptor interactions between small molecules. Chem Commun (Camb) (2015) 0.78

Variable gelation time and stiffness of low-molecular-weight hydrogels through catalytic control over self-assembly. Nat Protoc (2014) 0.78

Supramolecular Glycosylation Accelerates Proteolytic Degradation of Peptide Nanofibrils. J Am Chem Soc (2015) 0.78

Enzyme-Instructed Self-Assembly for Spatiotemporal Profiling of the Activities of Alkaline Phosphatases on Live Cells. Chem (2016) 0.77

Self-assembly mechanisms of nanofibers from peptide amphiphiles in solution and on substrate surfaces. Nanoscale (2016) 0.77

Enzymatic Dissolution of Biocomposite Solids Consisting of Phosphopeptides to Form Supramolecular Hydrogels. Chemistry (2015) 0.77

Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance. J Am Chem Soc (2016) 0.76

Peptide-drug conjugates as effective prodrug strategies for targeted delivery. Adv Drug Deliv Rev (2016) 0.76

A slippery molecular assembly allows water as a self-erasable security marker. Sci Rep (2015) 0.75

The Enzyme-instructed assembly of the core of yeast prion Sup35 to form supramolecular hydrogels. J Mater Chem B Mater Biol Med (2016) 0.75

DEVD-based hydrogelator minimizes cellular apoptosis induction. Sci Rep (2013) 0.75

Chemical reactions directed Peptide self-assembly. Int J Mol Sci (2015) 0.75

Far-red/near-infrared fluorescence light-up probes for specific in vitro and in vivo imaging of a tumour-related protein. Sci Rep (2016) 0.75

Nanonets Collect Cancer Secretome from Pericellular Space. PLoS One (2016) 0.75

Smart Nanotransformers with Unique Enzyme-Inducible Structural Changes and Drug Release Properties. Biomacromolecules (2016) 0.75

Supramolecular Self-assembly of a Model Hydrogelator: Characterization of Fiber Formation and Morphology. Gels (2016) 0.75

Fabrication of novel biomaterials through molecular self-assembly. Nat Biotechnol (2003) 6.57

Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science (2004) 6.38

Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proc Natl Acad Sci U S A (2003) 5.50

Fluorescence microscopy. Nat Methods (2005) 4.06

The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence. Cell (1992) 3.59

Purification of the major protein-tyrosine-phosphatases of human placenta. J Biol Chem (1988) 3.54

Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds. Proc Natl Acad Sci U S A (2000) 3.41

Central dogma at the single-molecule level in living cells. Nature (2011) 3.00

Controlling hydrogelation kinetics by peptide design for three-dimensional encapsulation and injectable delivery of cells. Proc Natl Acad Sci U S A (2007) 2.87

Self-assembly of peptide amphiphiles: from molecules to nanostructures to biomaterials. Biopolymers (2010) 2.86

Supramolecular gels: functions and uses. Chem Soc Rev (2005) 2.48

Water gelation by small organic molecules. Chem Rev (2004) 2.45

Enzymatic hydrogelation of small molecules. Acc Chem Res (2008) 2.02

Designing peptide based nanomaterials. Chem Soc Rev (2008) 1.85

Enzyme-instructed molecular self-assembly confers nanofibers and a supramolecular hydrogel of taxol derivative. J Am Chem Soc (2009) 1.67

Enzyme-triggered self-assembly of peptide hydrogels via reversed hydrolysis. J Am Chem Soc (2006) 1.58

Enzyme-assisted self-assembly under thermodynamic control. Nat Nanotechnol (2008) 1.55

A biocompatible condensation reaction for controlled assembly of nanostructures in living cells. Nat Chem (2009) 1.54

Molecular hydrogels of therapeutic agents. Chem Soc Rev (2009) 1.44

Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin. J Biol Chem (2007) 1.44

Rheological properties of peptide-based hydrogels for biomedical and other applications. Chem Soc Rev (2010) 1.37

Biocatalytic induction of supramolecular order. Nat Chem (2010) 1.30

Electron microscopy of the actin-myosin head complex in the presence of ATP. J Mol Biol (1992) 1.29

Using a kinase/phosphatase switch to regulate a supramolecular hydrogel and forming the supramolecular hydrogel in vivo. J Am Chem Soc (2006) 1.25

Intracellular hydrogelation of small molecules inhibits bacterial growth. Angew Chem Int Ed Engl (2007) 1.23

In vitro and in vivo enzymatic formation of supramolecular hydrogels based on self-assembled nanofibers of a beta-amino acid derivative. Small (2007) 1.11

Synthesis of phosphotyrosine-containing peptides and their use as substrates for protein tyrosine phosphatases. Biochemistry (1993) 1.00

Pi-organogels of self-assembled p-phenylenevinylenes: soft materials with distinct size, shape, and functions. Acc Chem Res (2007) 0.99

Subcellular distribution of inorganic and methylated arsenic compounds in human urothelial cells and human hepatocytes. Drug Metab Dispos (2008) 0.97

White-light-emitting self-assembled nanofibers and their evidence by microspectroscopy of individual objects. J Am Chem Soc (2010) 0.92

A fluorescent analog of colcemid, N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-colcemid, as a probe for the colcemid-binding sites of tubulin and microtubules. J Biol Chem (1987) 0.91

Cytoskeletal-like supramolecular assembly and nanoparticle-based motors in a model protocell. Angew Chem Int Ed Engl (2011) 0.90

Interfacial self-assembly of cell-like filamentous microcapsules. Angew Chem Int Ed Engl (2011) 0.89

L-lysine-based low-molecular-weight gelators. Chem Soc Rev (2009) 0.87

Cooperation between artificial receptors and supramolecular hydrogels for sensing and discriminating phosphate derivatives. J Am Chem Soc (2005) 0.86

Multifunctional magnetic nanoparticles: design, synthesis, and biomedical applications. Acc Chem Res (2009) 3.04

Dopamine as a robust anchor to immobilize functional molecules on the iron oxide shell of magnetic nanoparticles. J Am Chem Soc (2004) 2.54

Spatial analysis of hemorrhagic fever with renal syndrome in China. BMC Infect Dis (2006) 2.42

Environmental factors contributing to the spread of H5N1 avian influenza in mainland China. PLoS One (2008) 2.14

Enzymatic hydrogelation of small molecules. Acc Chem Res (2008) 2.02

Efficacy and safety of intracameral triamcinolone acetonide to control postoperative inflammation after phacotrabeculectomy. J Cataract Refract Surg (2013) 2.00

Biofunctional magnetic nanoparticles for protein separation and pathogen detection. Chem Commun (Camb) (2006) 1.85

Spatio-temporal distribution of malaria in Yunnan Province, China. Am J Trop Med Hyg (2009) 1.81

FePt@CoS(2) yolk-shell nanocrystals as a potent agent to kill HeLa cells. J Am Chem Soc (2007) 1.80

Enzyme-instructed molecular self-assembly confers nanofibers and a supramolecular hydrogel of taxol derivative. J Am Chem Soc (2009) 1.67

Facile one-pot synthesis of bifunctional heterodimers of nanoparticles: a conjugate of quantum dot and magnetic nanoparticles. J Am Chem Soc (2004) 1.59

Delayed build-up of Arctic ice sheets during 400,000-year minima in insolation variability. Nature (2012) 1.53

Nitrilotriacetic acid-modified magnetic nanoparticles as a general agent to bind histidine-tagged proteins. J Am Chem Soc (2004) 1.45

Developed and developing world responsibilities for historical climate change and CO2 mitigation. Proc Natl Acad Sci U S A (2012) 1.44

Molecular hydrogels of therapeutic agents. Chem Soc Rev (2009) 1.44

Versatile small-molecule motifs for self-assembly in water and the formation of biofunctional supramolecular hydrogels. Langmuir (2010) 1.39

Gene therapy for acute myeloid leukemia using Sindbis vectors expressing a fusogenic membrane glycoprotein. Cancer Biol Ther (2010) 1.39

Using biofunctional magnetic nanoparticles to capture vancomycin-resistant enterococci and other gram-positive bacteria at ultralow concentration. J Am Chem Soc (2003) 1.39

Multivariate detection limits of on-line NIR model for extraction process of chlorogenic acid from Lonicera japonica. J Pharm Biomed Anal (2013) 1.39

NIR spectroscopy as a process analytical technology (PAT) tool for monitoring and understanding of a hydrolysis process. Bioresour Technol (2013) 1.36

Supramolecular hydrogels respond to ligand-receptor interaction. J Am Chem Soc (2003) 1.34

Heterodimers of nanoparticles: formation at a liquid-liquid interface and particle-specific surface modification by functional molecules. J Am Chem Soc (2005) 1.32

Magnetic nanoparticles for the manipulation of proteins and cells. Chem Soc Rev (2012) 1.28

Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines. Cancer Lett (2009) 1.27

Hydrophobic interaction and hydrogen bonding cooperatively confer a vancomycin hydrogel: a potential candidate for biomaterials. J Am Chem Soc (2002) 1.27

Using a kinase/phosphatase switch to regulate a supramolecular hydrogel and forming the supramolecular hydrogel in vivo. J Am Chem Soc (2006) 1.25

D-amino acids boost the selectivity and confer supramolecular hydrogels of a nonsteroidal anti-inflammatory drug (NSAID). J Am Chem Soc (2012) 1.25

Pericellular hydrogel/nanonets inhibit cancer cells. Angew Chem Int Ed Engl (2014) 1.24

Intracellular hydrogelation of small molecules inhibits bacterial growth. Angew Chem Int Ed Engl (2007) 1.23

Spectrum of different types of hypophysitis: a clinicopathologic study of hypophysitis in 31 cases. Endocr Pathol (2002) 1.22

Single-molecule force spectroscopy and imaging of the vancomycin/D-Ala-D-Ala interaction. Nano Lett (2007) 1.20

Aromatic-aromatic interactions induce the self-assembly of pentapeptidic derivatives in water to form nanofibers and supramolecular hydrogels. J Am Chem Soc (2010) 1.20

Anthocyanins from Chinese bayberry extract protect β cells from oxidative stress-mediated injury via HO-1 upregulation. J Agric Food Chem (2010) 1.20

Dephosphorylation of D-peptide derivatives to form biofunctional, supramolecular nanofibers/hydrogels and their potential applications for intracellular imaging and intratumoral chemotherapy. J Am Chem Soc (2013) 1.20

The BCL2 gene is regulated by a special AT-rich sequence binding protein 1-mediated long range chromosomal interaction between the promoter and the distal element located within the 3'-UTR. Nucleic Acids Res (2011) 1.16

Study of 27 aqueous humor cytokines in patients with type 2 diabetes with or without retinopathy. Mol Vis (2013) 1.16

TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development? Am J Physiol Lung Cell Mol Physiol (2012) 1.15

Multifunctional yolk-shell nanoparticles: a potential MRI contrast and anticancer agent. J Am Chem Soc (2008) 1.15

Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J (2007) 1.14

D-amino acids modulate the cellular response of enzymatic-instructed supramolecular nanofibers of small peptides. Biomacromolecules (2014) 1.14

Supramolecular hydrogel of a D-amino acid dipeptide for controlled drug release in vivo. Langmuir (2009) 1.13

Synergistic effect of TGF-beta superfamily members on the induction of Foxp3+ Treg. Eur J Immunol (2010) 1.13

Disruption of the dynamics of microtubules and selective inhibition of glioblastoma cells by nanofibers of small hydrophobic molecules. Angew Chem Int Ed Engl (2013) 1.13

Enhancing effect of natural borneol on the absorption of geniposide in rat via intranasal administration. J Zhejiang Univ Sci B (2011) 1.13

In vitro and in vivo enzymatic formation of supramolecular hydrogels based on self-assembled nanofibers of a beta-amino acid derivative. Small (2007) 1.11

Contrasting below-ground views of an ectomycorrhizal fungal community. New Phytol (2005) 1.11

Combining spatial-temporal and phylogenetic analysis approaches for improved understanding on global H5N1 transmission. PLoS One (2010) 1.10

Using beta-lactamase to trigger supramolecular hydrogelation. J Am Chem Soc (2007) 1.09

Intracellular spatial control of fluorescent magnetic nanoparticles. J Am Chem Soc (2008) 1.08

99mTc-labeled cyclic RGDfK dimer: initial evaluation for SPECT imaging of glioma integrin alphavbeta3 expression. Bioconjug Chem (2006) 1.07

On temporal partitioning of a community of ectomycorrhizal fungi. New Phytol (2007) 1.05

Characterization of an H10N8 influenza virus isolated from Dongting lake wetland. Virol J (2011) 1.05

Evidence of species interactions within an ectomycorrhizal fungal community. New Phytol (2005) 1.04

Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage. Mutat Res (2008) 1.04

Near-infrared photoluminescent Ag2S quantum dots from a single source precursor. J Am Chem Soc (2010) 1.03

Real-time PCR for detecting circulating dengue virus in the Guangdong Province of China in 2006. J Med Microbiol (2008) 1.03

Small peptide nanofibers as the matrices of molecular hydrogels for mimicking enzymes and enhancing the activity of enzymes. Chem Soc Rev (2010) 1.03

Validation of a NIR quantification method for the determination of chlorogenic acid in Lonicera japonica solution in ethanol precipitation process. J Pharm Biomed Anal (2011) 1.02

Human infection with influenza virus A(H10N8) from live poultry markets, China, 2014. Emerg Infect Dis (2014) 1.02

An efficient conservative treatment modality for cervical pregnancy: angiographic uterine artery embolization followed by immediate curettage. Am J Obstet Gynecol (2011) 1.02

Using supramolecular hydrogels to discover the interactions between proteins and molecular nanofibers of small molecules. Chem Commun (Camb) (2012) 1.02

Magnetic resonance imaging in the diagnosis of intra-articular adhesions of the temporomandibular joint. Br J Oral Maxillofac Surg (2008) 1.01

Double-deformable-mirror adaptive optics system for phase compensation. Appl Opt (2006) 1.01

A supramolecular-hydrogel-encapsulated hemin as an artificial enzyme to mimic peroxidase. Angew Chem Int Ed Engl (2007) 0.99

Multifunctional, biocompatible supramolecular hydrogelators consist only of nucleobase, amino acid, and glycoside. J Am Chem Soc (2011) 0.99

Enzyme-instructed self-assembly of peptide derivatives to form nanofibers and hydrogels. Biopolymers (2010) 0.98

Evaluating team-based, lecture-based, and hybrid learning methods for neurology clerkship in China: a method-comparison study. BMC Med Educ (2014) 0.98

Berberine radiosensitizes human esophageal cancer cells by downregulating homologous recombination repair protein RAD51. PLoS One (2011) 0.97

Introducing D-amino acid or simple glycoside into small peptides to enable supramolecular hydrogelators to resist proteolysis. Langmuir (2012) 0.97

Promoter of a cotton fibre MYB gene functional in trichomes of Arabidopsis and glandular trichomes of tobacco. J Exp Bot (2008) 0.97

Demethoxycurcumin, a natural derivative of curcumin attenuates LPS-induced pro-inflammatory responses through down-regulation of intracellular ROS-related MAPK/NF-kappaB signaling pathways in N9 microglia induced by lipopolysaccharide. Int Immunopharmacol (2009) 0.97

53BP1 functions as a tumor suppressor in breast cancer via the inhibition of NF-κB through miR-146a. Carcinogenesis (2012) 0.96

A simple visual assay based on small molecule hydrogels for detecting inhibitors of enzymes. Chem Commun (Camb) (2004) 0.96

Molecular nanofibers of olsalazine form supramolecular hydrogels for reductive release of an anti-inflammatory agent. J Am Chem Soc (2010) 0.96

Sumoylation activates the transcriptional activity of Pax-6, an important transcription factor for eye and brain development. Proc Natl Acad Sci U S A (2010) 0.96

Molecular hydrogel-immobilized enzymes exhibit superactivity and high stability in organic solvents. Chem Commun (Camb) (2007) 0.96

Acylated phenylethanoid oligoglycosides with hepatoprotective activity from the desert plant Cistanche tubulosa. Bioorg Med Chem (2010) 0.94

A biocompatible method of decorporation: bisphosphonate-modified magnetite nanoparticles to remove uranyl ions from blood. J Am Chem Soc (2006) 0.94

Serum B7-H4 expression is a significant prognostic indicator for patients with gastric cancer. World J Surg Oncol (2014) 0.93

Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage. Aging Cell (2013) 0.93

Exceptionally small supramolecular hydrogelators based on aromatic-aromatic interactions. Beilstein J Org Chem (2011) 0.93

Ectopic expression of a COOH-terminal fragment of the human telomerase reverse transcriptase leads to telomere dysfunction and reduction of growth and tumorigenicity in HeLa cells. Cancer Res (2002) 0.92

FLASH is required for the endonucleolytic cleavage of histone pre-mRNAs but is dispensable for the 5' exonucleolytic degradation of the downstream cleavage product. Mol Cell Biol (2011) 0.92

Supramolecular nanofibers and hydrogels of nucleopeptides. Angew Chem Int Ed Engl (2011) 0.92

D-glucosamine-based supramolecular hydrogels to improve wound healing. Chem Commun (Camb) (2006) 0.92

Molecular recognition remolds the self-assembly of hydrogelators and increases the elasticity of the hydrogel by 10(6)-fold. J Am Chem Soc (2004) 0.92

Image-guided surgical navigation for removal of foreign bodies in the deep maxillofacial region. J Oral Maxillofac Surg (2013) 0.92

Characterization of low-pathogenic H6N6 avian influenza viruses in central China. Arch Virol (2012) 0.92

Identification of avermectin-high-producing strains by high-throughput screening methods. Appl Microbiol Biotechnol (2009) 0.91

Risk factors for infectious diseases in backyard poultry farms in the Poyang Lake area, China. PLoS One (2013) 0.91