Anette Müllertz

Author PubWeight™ 45.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Examination of oral absorption and lymphatic transport of halofantrine in a triple-cannulated canine model after administration in self-microemulsifying drug delivery systems (SMEDDS) containing structured triglycerides. Eur J Pharm Sci 2003 1.21
2 Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories. Eur J Pharm Sci 2008 1.16
3 Meeting report: applied biopharmaceutics and quality by design for dissolution/release specification setting: product quality for patient benefit. AAPS J 2010 1.11
4 Bioavailability of cinnarizine in dogs: effect of SNEDDS loading level and correlation with cinnarizine solubilization during in vitro lipolysis. Pharm Res 2013 1.10
5 Bioavailability of seocalcitol II: development and characterisation of self-microemulsifying drug delivery systems (SMEDDS) for oral administration containing medium and long chain triglycerides. Eur J Pharm Sci 2006 0.99
6 Bioavailability of seocalcitol I: Relating solubility in biorelevant media with oral bioavailability in rats--effect of medium and long chain triglycerides. J Pharm Sci 2005 0.99
7 In vivo in vitro correlations for a poorly soluble drug, danazol, using the flow-through dissolution method with biorelevant dissolution media. Eur J Pharm Sci 2005 0.99
8 Lipid-based formulations for oral administration of poorly water-soluble drugs. Int J Pharm 2013 0.95
9 Bioavailability of probucol from lipid and surfactant based formulations in minipigs: influence of droplet size and dietary state. Eur J Pharm Biopharm 2008 0.92
10 Toward the establishment of standardized in vitro tests for lipid-based formulations, part 1: method parameterization and comparison of in vitro digestion profiles across a range of representative formulations. J Pharm Sci 2012 0.91
11 Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug. Eur J Pharm Sci 2005 0.91
12 In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systems. Int J Pharm 2011 0.89
13 Lipid-based formulations for danazol containing a digestible surfactant, Labrafil M2125CS: in vivo bioavailability and dynamic in vitro lipolysis. Pharm Res 2008 0.88
14 Adsorption of pharmaceutical excipients onto microcrystals of siramesine hydrochloride: effects on physicochemical properties. Eur J Pharm Biopharm 2008 0.87
15 Characterization of prototype self-nanoemulsifying formulations of lipophilic compounds. J Pharm Sci 2007 0.87
16 Influence of the type of surfactant and the degree of dispersion on the lymphatic transport of halofantrine in conscious rats. Pharm Res 2004 0.85
17 Supersaturated self-nanoemulsifying drug delivery systems (Super-SNEDDS) enhance the bioavailability of the poorly water-soluble drug simvastatin in dogs. AAPS J 2012 0.85
18 Oral bioavailability of cinnarizine in dogs: relation to SNEDDS droplet size, drug solubility and in vitro precipitation. Eur J Pharm Sci 2012 0.85
19 Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate. J Pharm Sci 2010 0.85
20 Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations. Pharm Res 2013 0.84
21 Toward the establishment of standardized in vitro tests for lipid-based formulations. 2. The effect of bile salt concentration and drug loading on the performance of type I, II, IIIA, IIIB, and IV formulations during in vitro digestion. Mol Pharm 2012 0.84
22 Characterising the behaviour of poorly water soluble drugs in the intestine: application of biorelevant media for solubility, dissolution and transport studies. J Pharm Pharmacol 2010 0.84
23 Influence of bile on the absorption of halofantrine from lipid-based formulations. Eur J Pharm Biopharm 2012 0.83
24 Influence of lipid composition and drug load on the In Vitro performance of self-nanoemulsifying drug delivery systems. J Pharm Sci 2012 0.83
25 Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats. Pharm Res 2002 0.83
26 Phase transformations of amlodipine besylate solid forms. J Pharm Sci 2011 0.82
27 Bile salts and their importance for drug absorption. Int J Pharm 2013 0.82
28 Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80. Eur J Pharm Sci 2008 0.82
29 Enzymatic characterization of lipid-based drug delivery systems. Int J Pharm 2005 0.81
30 Characterising lipid lipolysis and its implication in lipid-based formulation development. AAPS J 2012 0.81
31 Using biorelevant dissolution to obtain IVIVC of solid dosage forms containing a poorly-soluble model compound. Eur J Pharm Biopharm 2007 0.81
32 Colloidal structures in media simulating intestinal fed state conditions with and without lipolysis products. Pharm Res 2008 0.81
33 Bioavailability of seocalcitol III. Administration of lipid-based formulations to minipigs in the fasted and fed state. Eur J Pharm Sci 2007 0.80
34 The biopharmaceutics risk assessment roadmap for optimizing clinical drug product performance. J Pharm Sci 2014 0.80
35 In vitro lipolysis data does not adequately predict the in vivo performance of lipid-based drug delivery systems containing fenofibrate. AAPS J 2014 0.80
36 Feasibility of capsule endoscopy for direct imaging of drug delivery systems in the fasted upper-gastrointestinal tract. Pharm Res 2014 0.80
37 Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity. J Pharm Sci 2010 0.80
38 Solid lipid particles for oral delivery of peptide and protein drugs II--the digestion of trilaurin protects desmopressin from proteolytic degradation. Pharm Res 2014 0.80
39 Solid lipid particles for oral delivery of peptide and protein drugs III - the effect of fed state conditions on the in vitro release and degradation of desmopressin. AAPS J 2014 0.79
40 Investigating the correlation between in vivo absorption and in vitro release of fenofibrate from lipid matrix particles in biorelevant medium. Eur J Pharm Sci 2013 0.79
41 Biorelevant dissolution media: aggregation of amphiphiles and solubility of estradiol. J Pharm Sci 2006 0.79
42 Oral delivery of peptides and proteins using lipid-based drug delivery systems. Expert Opin Drug Deliv 2012 0.79
43 Characterization of fasted human gastric fluid for relevant rheological parameters and gastric lipase activities. Eur J Pharm Biopharm 2013 0.78
44 Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis. Int J Pharm 2012 0.78
45 Toward the establishment of standardized in vitro tests for lipid-based formulations, part 6: effects of varying pancreatin and calcium levels. AAPS J 2014 0.78
46 Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology. Drug Dev Ind Pharm 2012 0.78
47 The Effect of Digestion and Drug Load on Halofantrine Absorption from Self-nanoemulsifying Drug Delivery System (SNEDDS). AAPS J 2016 0.77
48 Preparation of an amorphous sodium furosemide salt improves solubility and dissolution rate and leads to a faster Tmax after oral dosing to rats. Eur J Pharm Biopharm 2013 0.77
49 Effect of different surfactants in biorelevant medium on the secretion of a lipophilic compound in lipoproteins using Caco-2 cell culture. J Pharm Sci 2006 0.77
50 Effect of bile on the oral absorption of halofantrine in polyethylene glycol 400 and polysorbate 80 formulations dosed to bile duct cannulated rats. J Pharm Pharmacol 2011 0.77
51 SNEDDS Containing Poorly Water Soluble Cinnarizine; Development and in Vitro Characterization of Dispersion, Digestion and Solubilization. Pharmaceutics 2012 0.76
52 Insights into the early dissolution events of amlodipine using UV imaging and Raman spectroscopy. Mol Pharm 2011 0.76
53 Bioavailability of seocalcitol IV: evaluation of lymphatic transport in conscious rats. Pharm Res 2006 0.76
54 pH-triggered drug release from biodegradable microwells for oral drug delivery. Biomed Microdevices 2015 0.75
55 Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system. J Pharm Sci 2014 0.75
56 Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging. Pharm Dev Technol 2012 0.75
57 Toward the establishment of standardized in vitro tests for lipid-based formulations. 5. Lipolysis of representative formulations by gastric lipase. Pharm Res 2014 0.75
58 Miniaturized approach for excipient selection during the development of oral solid dosage form. J Pharm Sci 2014 0.75
59 In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems. J Pharm Pharmacol 2014 0.75
60 Determination of surface-adsorbed excipients of various types on drug particles prepared by antisolvent precipitation using HPLC with evaporative light scattering detection. J Pharm Biomed Anal 2007 0.75
61 A novel excipient, 1-perfluorohexyloctane shows limited utility for the oral delivery of poorly water-soluble drugs. Eur J Pharm Sci 2011 0.75
62 Azone® decreases the buccal mucosal permeation of diazepam in a concentration-dependent manner via a reservoir effect. J Pharm Sci 2014 0.75
63 Spatial confinement can lead to increased stability of amorphous indomethacin. Eur J Pharm Biopharm 2012 0.75
64 Biorelevant characterisation of amorphous furosemide salt exhibits conversion to a furosemide hydrate during dissolution. Int J Pharm 2013 0.75
65 Using resin to generate a non-invasive intestinal bile-depleted rat model was unsuccessful. Eur J Pharm Sci 2012 0.75
66 Development of simulated intestinal fluids containing nutrients as transport media in the Caco-2 cell culture model: assessment of cell viability, monolayer integrity and transport of a poorly aqueous soluble drug and a substrate of efflux mechanisms. Eur J Pharm Sci 2007 0.75
67 A new approach to dissolution testing by UV imaging and finite element simulations. Pharm Res 2013 0.75
68 Preparation and characterization of insulin-surfactant complexes for loading into lipid-based drug delivery systems. J Pharm Sci 2013 0.75
69 Ex vivo correlation of the permeability of metoprolol across human and porcine buccal mucosa. J Pharm Sci 2014 0.75
70 Investigation of the intra- and inter-laboratory reproducibility of a small scale standardized supersaturation and precipitation method. Mol Pharm 2017 0.75
71 Evaluation of the use of Göttingen minipigs to predict food effects on the oral absorption of drugs in humans. J Pharm Sci 2014 0.75
72 A slow cooling rate of indomethacin melt spatially confined in microcontainers increases the physical stability of the amorphous drug without influencing its biorelevant dissolution behaviour. Drug Deliv Transl Res 2014 0.75
73 Effects of polysorbate 80 on the in-vitro precipitation and oral bioavailability of halofantrine from polyethylene glycol 400 formulations in rats. J Pharm Pharmacol 2010 0.75
74 Influence of the solid form of siramesine hydrochloride on its behavior in aqueous environments. Pharm Res 2008 0.75