Published in J Cell Sci on September 03, 2012
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer. J Physiol (2013) 1.35
Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation. Cell Death Differ (2014) 1.00
Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus. J Biol Chem (2015) 0.88
Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress. Neuroscience (2015) 0.82
The role of PHD2 mutations in the pathogenesis of erythrocytosis. Hypoxia (Auckl) (2014) 0.80
Tumor PHD2 expression is correlated with clinical features and prognosis of patients with HCC receiving liver resection. Medicine (Baltimore) (2014) 0.80
The Roles and Mechanisms of Actions of Vitamin C in Bone: New Developments. J Bone Miner Res (2015) 0.80
A Genetically Encoded FRET Sensor for Hypoxia and Prolyl Hydroxylases. ACS Chem Biol (2016) 0.75
Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular permeability by targeting prolyl hydroxylase and tight junction protein ZO-1. Oncogene (2017) 0.75
A large-scale analysis of mRNA polyadenylation of human and mouse genes. Nucleic Acids Res (2005) 7.24
Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing. J Cell Sci (2003) 2.46
Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor. Proc Natl Acad Sci U S A (2012) 2.27
Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB. Biochem J (2006) 2.13
Isolation and characterization of tumorigenic extrahepatic cholangiocarcinoma cells with stem cell-like properties. Int J Cancer (2011) 2.12
Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases. Mol Biol Cell (2003) 2.11
PolyA_DB: a database for mammalian mRNA polyadenylation. Nucleic Acids Res (2005) 1.99
Kinetics of avibactam inhibition against Class A, C, and D β-lactamases. J Biol Chem (2013) 1.89
Design of HIV vectors for efficient gene delivery into human hematopoietic cells. Mol Ther (2002) 1.85
A charge-driven molecular water pump. Nat Nanotechnol (2007) 1.76
A current sensor based on the giant magnetoresistance effect: design and potential smart grid applications. Sensors (Basel) (2012) 1.74
High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice. Am J Physiol Endocrinol Metab (2013) 1.57
Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: a clinical and in vitro investigation. Oncol Rep (2013) 1.56
Loss of collectrin, an angiotensin-converting enzyme 2 homolog, uncouples endothelial nitric oxide synthase and causes hypertension and vascular dysfunction. Circulation (2013) 1.54
An alternative splice variant in Abcc6, the gene causing dystrophic calcification, leads to protein deficiency in C3H/He mice. J Biol Chem (2008) 1.51
The genome of Mesobuthus martensii reveals a unique adaptation model of arthropods. Nat Commun (2013) 1.50
Altered pulmonary vascular reactivity in mice with excessive erythrocytosis. Am J Respir Crit Care Med (2003) 1.48
Fc-fusion proteins: new developments and future perspectives. EMBO Mol Med (2012) 1.44
MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression. Oncotarget (2014) 1.44
Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest (2016) 1.42
Stable liquid water droplet on a water monolayer formed at room temperature on ionic model substrates. Phys Rev Lett (2009) 1.41
ImageMiner: a software system for comparative analysis of tissue microarrays using content-based image retrieval, high-performance computing, and grid technology. J Am Med Inform Assoc (2011) 1.40
PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancer. PLoS One (2013) 1.39
Quantitative analysis of redox-sensitive proteome with DIGE and ICAT. J Proteome Res (2008) 1.37
A peptide motif consisting of glycine, alanine, and valine is required for the fibrillization and cytotoxicity of human alpha-synuclein. Biochemistry (2003) 1.30
Solid-state NMR and MD simulations of the antiviral drug amantadine solubilized in DMPC bilayers. Biophys J (2007) 1.29
Comparative genome analysis of lignin biosynthesis gene families across the plant kingdom. BMC Bioinformatics (2009) 1.29
Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2. J Biol Chem (2006) 1.29
Regulation of hypoxia-inducible factors during inflammation. Methods Enzymol (2007) 1.29
A method for aligning RNA secondary structures and its application to RNA motif detection. BMC Bioinformatics (2005) 1.25
The proinflammatory cytokine interleukin 1beta and hypoxia cooperatively induce the expression of adrenomedullin in ovarian carcinoma cells through hypoxia inducible factor 1 activation. Cancer Res (2005) 1.24
Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression. Clin Exp Pharmacol Physiol (2006) 1.21
A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression. Proc Natl Acad Sci U S A (2004) 1.17
Combined blockade of AT1-receptors and ACE synergistically potentiates antihypertensive effects in SHR. J Hypertens (2004) 1.17
Hypoxia-induced mitogenic factor has antiapoptotic action and is upregulated in the developing lung: coexpression with hypoxia-inducible factor-2alpha. Am J Respir Cell Mol Biol (2004) 1.16
Intrinsic spin Seebeck effect in Au/YIG. Phys Rev Lett (2013) 1.15
Design, Synthesis, and Crystal Structure of a cis-Configuration N(2)S(2)-Coordinated Palladium(II) Complex: Role of the Intra- and Intermolecular Aromatic-Ring Stacking Interaction. Inorg Chem (1999) 1.14
Acute toxicity of berberine and its correlation with the blood concentration in mice. Food Chem Toxicol (2010) 1.14
Distinctive nicotinic acetylcholine receptor functional phenotypes of rat ventral tegmental area dopaminergic neurons. J Physiol (2008) 1.14
beta-Amyloid directly inhibits human alpha4beta2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells. J Biol Chem (2004) 1.14
A Protocol for the secure linking of registries for HPV surveillance. PLoS One (2012) 1.13
Conductometric chemical sensor based on individual CuO nanowires. Nanotechnology (2010) 1.11
Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells. Blood (2002) 1.11
Identification of differentially expressed proteins in experimental autoimmune encephalomyelitis (EAE) by proteomic analysis of the spinal cord. J Proteome Res (2007) 1.11
A secure protocol for protecting the identity of providers when disclosing data for disease surveillance. J Am Med Inform Assoc (2011) 1.10
Analysis of RF heating and sample stability in aligned static solid-state NMR spectroscopy. J Magn Reson (2006) 1.10
Hypoxia rapidly activates HIF-3alpha mRNA expression. FASEB J (2003) 1.09
Bridging small-gap peripheral nerve defects using acellular nerve allograft implanted with autologous bone marrow stromal cells in primates. Brain Res (2007) 1.08
Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38. J Biol Chem (2009) 1.08
(S)-Ethyl 2-[4-(6-chloro-quinoxalin-2-yl-oxy)phen-oxy]propanoate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.07
Importin alpha3 interacts with HIV-1 integrase and contributes to HIV-1 nuclear import and replication. J Virol (2010) 1.07
NO and TNF-alpha released from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells. Am J Physiol Cell Physiol (2002) 1.07
Mutual effects of Pb(II) and humic acid adsorption on multiwalled carbon nanotubes/polyacrylamide composites from aqueous solutions. Environ Sci Technol (2011) 1.07
Identification of protein disulfide isomerase as a cardiomyocyte survival factor in ischemic cardiomyopathy. J Am Coll Cardiol (2007) 1.07
Hepatic erythropoietin gene regulation by GATA-4. J Biol Chem (2003) 1.06
Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. J Biol Chem (2009) 1.04
Roles of nicotinic acetylcholine receptor beta subunits in function of human alpha4-containing nicotinic receptors. J Physiol (2006) 1.04
Prevention of metastasis in a 4T1 murine breast cancer model by doxorubicin carried by folate conjugated pH sensitive polymeric micelles. J Control Release (2011) 1.04
The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases. Cardiovasc Res (2006) 1.03
Alignment of osteoblast-like cells and cell-produced collagen matrix induced by nanogrooves. Tissue Eng (2005) 1.01
Glioma-initiating cells: a predominant role in microglia/macrophages tropism to glioma. J Neuroimmunol (2010) 1.01
Multiple frequencies sequential coding for SSVEP-based brain-computer interface. PLoS One (2012) 1.01
MicroRNA-146a feedback suppresses T cell immune function by targeting Stat1 in patients with chronic hepatitis B. J Immunol (2013) 1.00
A DNA-Origami chip platform for label-free SNP genotyping using toehold-mediated strand displacement. Small (2010) 1.00
Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site. J Cell Biochem (2004) 1.00
Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha. J Biol Chem (2004) 0.99
Generating aptamers by cell-SELEX for applications in molecular medicine. Int J Mol Sci (2012) 0.99
Candida antarctica lipase B chemically immobilized on epoxy-activated micro- and nanobeads: catalysts for polyester synthesis. Biomacromolecules (2008) 0.99
The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis. Anesthesiology (2013) 0.99
Inhibition of alpha-synuclein fibrillization by dopamine analogs via reaction with the amino groups of alpha-synuclein. Implication for dopaminergic neurodegeneration. FEBS J (2005) 0.98
α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation. J Neuroinflammation (2012) 0.98
Thrombopoietin production in wild-type and interleukin-6 knockout mice with acute inflammation. J Interferon Cytokine Res (2005) 0.98
Adsorption of Ni(II) on oxidized multi-walled carbon nanotubes: effect of contact time, pH, foreign ions and PAA. J Hazard Mater (2008) 0.98
NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum. J Biol Chem (2004) 0.98
Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol (2009) 0.97
A cancer-recognizable MRI contrast agents using pH-responsive polymeric micelle. Biomaterials (2013) 0.97
Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN. Mol Cell Biol (2003) 0.97
Restraint stress modulates brain, pituitary and adrenal expression of angiotensin II AT(1A), AT(1B) and AT(2) receptors. Neuroendocrinology (2002) 0.97
Removal of induced nanobubbles from water/graphite interfaces by partial degassing. Langmuir (2006) 0.97
Seroprevalence of N-methyl-D-aspartate glutamate receptor (NMDA-R) autoantibodies in aging subjects without neuropsychiatric disorders and in dementia patients. Eur Arch Psychiatry Clin Neurosci (2014) 0.97
Nanoparticle PCR: nanogold-assisted PCR with enhanced specificity. Angew Chem Int Ed Engl (2005) 0.96
Moxibustion and other acupuncture point stimulation methods to treat breech presentation: a systematic review of clinical trials. Chin Med (2009) 0.96
Nanotopographical guidance of C6 glioma cell alignment and oriented growth. Biomaterials (2004) 0.96
A multiplexed proteomics approach to differentiate neurite outgrowth patterns. J Neurosci Methods (2006) 0.96
Activation of the hypothalamus characterizes the response to acupuncture stimulation in heroin addicts. Neurosci Lett (2007) 0.95
Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling. Nucleic Acids Res (2011) 0.95
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis. Blood (2012) 0.95
15N and 31P solid-state NMR study of transmembrane domain alignment of M2 protein of influenza A virus in hydrated cylindrical lipid bilayers confined to anodic aluminum oxide nanopores. J Magn Reson (2005) 0.95
Nuclear oxygen sensing: induction of endogenous prolyl-hydroxylase 2 activity by hypoxia and nitric oxide. J Biol Chem (2008) 0.95