Published in Biochem J on June 15, 2006
Hypoxia-inducible factors and the response to hypoxic stress. Mol Cell (2010) 7.20
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression. Nat Rev Cancer (2011) 6.32
Regulation of hypoxia-inducible factor-1alpha by NF-kappaB. Biochem J (2008) 3.98
Interdependence of hypoxic and innate immune responses. Nat Rev Immunol (2009) 3.29
The updated biology of hypoxia-inducible factor. EMBO J (2012) 2.49
Hypoxia up-regulates hypoxia-inducible factor-1alpha transcription by involving phosphatidylinositol 3-kinase and nuclear factor kappaB in pulmonary artery smooth muscle cells. Mol Biol Cell (2007) 2.47
Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis. Genes Dev (2010) 2.26
Interdependent roles for hypoxia inducible factor and nuclear factor-kappaB in hypoxic inflammation. J Physiol (2008) 2.01
HIF transcription factors, inflammation, and immunity. Immunity (2014) 1.55
Hypoxia-inducible factors as essential regulators of inflammation. Curr Top Microbiol Immunol (2010) 1.51
Hypoxia--a key regulator of angiogenesis and inflammation in rheumatoid arthritis. Nat Rev Rheumatol (2012) 1.41
Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens. PLoS One (2010) 1.29
Reactive oxygen species-generating mitochondrial DNA mutation up-regulates hypoxia-inducible factor-1alpha gene transcription via phosphatidylinositol 3-kinase-Akt/protein kinase C/histone deacetylase pathway. J Biol Chem (2009) 1.19
Role of HIF-1 and NF-kappaB transcription factors in the modulation of transferrin receptor by inflammatory and anti-inflammatory signals. J Biol Chem (2008) 1.13
Diabetic Retinopathy: Vascular and Inflammatory Disease. J Diabetes Res (2015) 1.13
Oxidative stress, hypoxia, and autophagy in the neovascular processes of age-related macular degeneration. Biomed Res Int (2014) 1.13
Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis. Arthritis Res Ther (2009) 1.09
Inflammatory levels of nitric oxide inhibit airway epithelial cell migration by inhibition of the kinase ERK1/2 and activation of hypoxia-inducible factor-1 alpha. J Biol Chem (2008) 1.08
Expression and significance of TLR4 and HIF-1alpha in pancreatic ductal adenocarcinoma. World J Gastroenterol (2010) 1.06
Novel roles for hypoxia and prostaglandin E2 in the regulation of IL-8 during endometrial repair. Am J Pathol (2011) 1.03
Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved? Redox Biol (2015) 1.02
FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4. Nat Commun (2013) 0.99
Interactions between nitric oxide and hypoxia-inducible factor signaling pathways in inflammatory disease. Nitric Oxide (2011) 0.99
Placenta growth factor-induced early growth response 1 (Egr-1) regulates hypoxia-inducible factor-1alpha (HIF-1alpha) in endothelial cells. J Biol Chem (2010) 0.96
MKP-1 negatively regulates LPS-mediated IL-1β production through p38 activation and HIF-1α expression. Cell Signal (2017) 0.96
Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases. Arthritis Res Ther (2009) 0.95
Expression and regulation of HIF-1alpha in macrophages under inflammatory conditions; significant reduction of VEGF by CaMKII inhibitor. BMC Musculoskelet Disord (2010) 0.94
Hypoxia-inducible factor 1 alpha expression increases during colorectal carcinogenesis and tumor progression. BMC Cancer (2008) 0.94
A genetic variant of hypoxia-inducible factor-1alpha is associated with adverse outcomes in acute kidney injury. Kidney Int (2009) 0.93
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells. Shock (2011) 0.93
12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells. Exp Cell Res (2010) 0.93
Molecular role of GATA binding protein 4 (GATA-4) in hyperglycemia-induced reduction of cardiac contractility. Cardiovasc Diabetol (2011) 0.92
Peroxiredoxin 1 stimulates endothelial cell expression of VEGF via TLR4 dependent activation of HIF-1α. PLoS One (2012) 0.92
Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage. PLoS One (2012) 0.92
Molecular mechanisms regulating macrophage response to hypoxia. Front Immunol (2011) 0.91
Hypoxia-inducible factor-1α (HIF1α) switches on transient receptor potential ankyrin repeat 1 (TRPA1) gene expression via a hypoxia response element-like motif to modulate cytokine release. J Biol Chem (2012) 0.91
Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages. J Biol Chem (2013) 0.89
The role of hypoxia in inflammatory disease (review). Int J Mol Med (2015) 0.89
Human monocytes and macrophages differ in their mechanisms of adaptation to hypoxia. Arthritis Res Ther (2012) 0.87
Differential expression and biochemical activity of the immune receptor Tim-3 in healthy and malignant human myeloid cells. Oncotarget (2015) 0.86
hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer. Sci Rep (2013) 0.86
Hypoxia-dependent regulation of inflammatory pathways in immune cells. J Clin Invest (2016) 0.86
Hypoxia-inducible factor-1alpha suppresses the expression of macrophage scavenger receptor 1. Pflugers Arch (2009) 0.85
Targeting aerobic glycolysis and HIF-1alpha expression enhance imiquimod-induced apoptosis in cancer cells. Oncotarget (2014) 0.85
Hypoxia-inducible factor 1-regulated lysyl oxidase is involved in Staphylococcus aureus abscess formation. Infect Immun (2013) 0.83
Hypoxia-Inducible Factor (HIF) as a Pharmacological Target for Prevention and Treatment of Infectious Diseases. Infect Dis Ther (2014) 0.82
Increased hypoxia-inducible factor 1α expression in lung cells of horses with recurrent airway obstruction. BMC Vet Res (2012) 0.82
Characterization of the mechanisms of the increase in PPARδ expression induced by digoxin in the heart using the H9c2 cell line. Br J Pharmacol (2011) 0.82
Hypoxia-inducible factor (HIF1α) gene expression in human shock states. Crit Care (2012) 0.80
Pseudomonas aeruginosa Alkyl quinolones repress hypoxia-inducible factor 1 (HIF-1) signaling through HIF-1α degradation. Infect Immun (2012) 0.80
Identification of HIF-1α promoter and expression regulation of HIF-1α gene by LPS and hypoxia in zebrafish. Fish Physiol Biochem (2013) 0.80
Hypoxia-inducible factors as molecular targets for liver diseases. J Mol Med (Berl) (2016) 0.79
Immunologic Consequences of Hypoxia during Critical Illness. Anesthesiology (2016) 0.79
(18)F-FDG imaging of human atherosclerotic carotid plaques reflects gene expression of the key hypoxia marker HIF-1α. Am J Nucl Med Mol Imaging (2013) 0.79
The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9. PLoS One (2011) 0.79
Vitreous mediators in retinal hypoxic diseases. Mediators Inflamm (2013) 0.79
Transcriptional repression of hypoxia-inducible factor-1 (HIF-1) by the protein arginine methyltransferase PRMT1. Mol Biol Cell (2014) 0.78
Hypoxia and P. gingivalis synergistically induce HIF-1 and NF-κB activation in PDL cells and periodontal diseases. Mediators Inflamm (2015) 0.78
Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity. J Immunol Res (2016) 0.78
Endotoxin-induced HIF-1alpha stabilisation in equine endothelial cells: synergistic action with hypoxia. Inflamm Res (2010) 0.78
Resveratrol alleviate hypoxic pulmonary hypertension via anti-inflammation and anti-oxidant pathways in rats. Int J Med Sci (2016) 0.77
No evidence for protective erythropoietin alpha signalling in rat hepatocytes. BMC Gastroenterol (2009) 0.77
The Response of Macrophages and Neutrophils to Hypoxia in the Context of Cancer and Other Inflammatory Diseases. Mediators Inflamm (2016) 0.77
Transcriptome Analysis of the Sydney Rock Oyster, Saccostrea glomerata: Insights into Molluscan Immunity. PLoS One (2016) 0.76
Ginsenoside Rh2 Downregulates LPS-Induced NF- κ B Activation through Inhibition of TAK1 Phosphorylation in RAW 264.7 Murine Macrophage. Evid Based Complement Alternat Med (2013) 0.76
Hypoxia and its implications in rheumatoid arthritis. J Biomed Sci (2016) 0.76
Oxygen sensing in intestinal mucosal inflammation. Pflugers Arch (2015) 0.76
Hypoxia-inducible factors: key regulators of myeloid cells during inflammation. J Clin Invest (2016) 0.75
Inverse Correlation between IL-10 and HIF-1α in Macrophages Infected with Histoplasma capsulatum. J Immunol (2016) 0.75
Hypoxia: from basic mechanisms to therapeutics - a meeting report on the Keystone and HypoxiaNet Symposium. Hypoxia (Auckl) (2015) 0.75
Metabolic zonation of the liver: The oxygen gradient revisited. Redox Biol (2017) 0.75
Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α Pathway. PLoS One (2016) 0.75
Transcription regulates HIF-1α expression in CD4(+) T cells. Immunol Cell Biol (2015) 0.75
Hypoxia inducible factor-1α-induced interleukin-33 expression in intestinal epithelia contributes to mucosal homeostasis in inflammatory bowel disease. Clin Exp Immunol (2016) 0.75
Association of Hypoxia-Inducible Factor-2 Alpha Gene Polymorphisms with the Risk of Hepatitis B Virus-Related Liver Disease in Guangxi Chinese: A Case-Control Study. PLoS One (2016) 0.75
Human activated macrophages and hypoxia: a comprehensive review of the literature. Iran J Basic Med Sci (2014) 0.75
Partial Enteral Nutrition Mitigated Ischemia/Reperfusion-Induced Damage of Rat Small Intestinal Barrier. Nutrients (2016) 0.75
Differential role of hypoxia-inducible factor 1 alpha in toll-like receptor-mediated and allergic inflammatory reactions. World Allergy Organ J (2010) 0.75
The Role of Hypoxia-Inducible Factor 1 in Mild Cognitive Impairment. Cell Mol Neurobiol (2016) 0.75
Effect of simvastatin on mitochondrial enzyme activities, ghrelin, hypoxia-inducible factor 1α in hepatic tissue during early phase of sepsis. Int J Clin Exp Med (2015) 0.75
Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis: a prospective observational trial. BMC Anesthesiol (2016) 0.75
Acute hypoxia decreases E. coli LPS-induced cytokine production and NF-kappaB activation in alveolar macrophages. Respir Physiol Neurobiol (2010) 0.75
Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma. PLoS One (2017) 0.75
The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages. PLoS One (2017) 0.75
Evaluation of Hypoxia Inducible Factor-1α and Glucose Transporter-1 Expression in Non Melanoma Skin Cancer: An Immunohistochemical Study. J Clin Diagn Res (2017) 0.75
Intestinal hypoxia and hypoxia-induced signalling as therapeutic targets for IBD. Nat Rev Gastroenterol Hepatol (2017) 0.75
Regulation of immunity and inflammation by hypoxia in immunological niches. Nat Rev Immunol (2017) 0.75
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science (2001) 23.83
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res (1989) 22.73
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science (2001) 22.06
Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J Immunol Methods (1989) 9.42
HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell (2003) 9.12
Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun (1993) 4.32
p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. J Biol Chem (1999) 3.90
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells. J Biol Chem (2000) 2.94
Interleukin-1beta and tumor necrosis factor-alpha stimulate DNA binding of hypoxia-inducible factor-1. Blood (1999) 2.35
Hypoxic gene activation by lipopolysaccharide in macrophages: implication of hypoxia-inducible factor 1alpha. Blood (2003) 2.28
Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4. J Biol Chem (2003) 2.20
Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases. Mol Biol Cell (2003) 2.11
ERK activation upon hypoxia: involvement in HIF-1 activation. FEBS Lett (2000) 1.81
Expression of hypoxia-inducible factor 1alpha by macrophages in the rheumatoid synovium: implications for targeting of therapeutic genes to the inflamed joint. Arthritis Rheum (2001) 1.71
MAPK signaling up-regulates the activity of hypoxia-inducible factors by its effects on p300. J Biol Chem (2003) 1.66
HIF-1 expression in healing wounds: HIF-1alpha induction in primary inflammatory cells by TNF-alpha. Am J Physiol Cell Physiol (2001) 1.61
Hypoxia-induced gene expression in human macrophages: implications for ischemic tissues and hypoxia-regulated gene therapy. Am J Pathol (2003) 1.58
Accumulation of HIF-1alpha under the influence of nitric oxide. Blood (2001) 1.55
HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O(2) levels. J Cell Sci (2003) 1.53
Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis. Mol Endocrinol (2000) 1.41
The hypoxia-inducible factors: key transcriptional regulators of hypoxic responses. Cell Mol Life Sci (2003) 1.40
Interleukin-1, tumor necrosis factor and lipopolysaccharide additively stimulate production of adrenomedullin in vascular smooth muscle cells. Biochem Biophys Res Commun (1995) 1.37
Lipopolysaccharide stimulation of ERK1/2 increases TNF-alpha production via Egr-1. Am J Physiol Cell Physiol (2002) 1.37
Lipopolysaccharide-induced tumor necrosis factor alpha production by human monocytes involves the raf-1/MEK1-MEK2/ERK1-ERK2 pathway. Infect Immun (1999) 1.33
Increased plasma concentrations of adrenomedullin correlate with relaxation of vascular tone in patients with septic shock. Crit Care Med (1997) 1.33
Increased circulating adrenomedullin, a novel vasodilatory peptide, in sepsis. J Clin Endocrinol Metab (1996) 1.33
The proinflammatory cytokine interleukin 1beta and hypoxia cooperatively induce the expression of adrenomedullin in ovarian carcinoma cells through hypoxia inducible factor 1 activation. Cancer Res (2005) 1.24
Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells. Kidney Int (2000) 1.20
A novel role for the hypoxia inducible transcription factor HIF-1alpha: critical regulation of inflammatory cell function. Cell Cycle (2003) 1.20
Production of adrenomedullin in macrophage cell line and peritoneal macrophage. J Biol Chem (1998) 1.15
Structure of MAPKs. Methods Mol Biol (2004) 1.02
Coordinated Up-regulation by hypoxia of adrenomedullin and one of its putative receptors (RDC-1) in cells of the rat blood-brain barrier. J Biol Chem (2000) 0.96
An unexpected role for hypoxic response: oxygenation and inflammation. Cell Cycle (2004) 0.94
Effects of hypoxia on monocyte inflammatory mediator production: Dissociation between changes in cyclooxygenase-2 expression and eicosanoid synthesis. J Biol Chem (2003) 0.90
Induction of adrenomedullin mRNA and protein by lipopolysaccharide and paclitaxel (Taxol) in murine macrophages. Infect Immun (1998) 0.87
Involvement of MAPK activation in bacterial endotoxin-inducible tissue factor upregulation in human monocytic THP-1 cells. J Surg Res (2001) 0.84
A role for VEGF as a negative regulator of pericyte function and vessel maturation. Nature (2008) 3.74
Foxo transcription factors control regulatory T cell development and function. Immunity (2010) 3.17
Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Res (2010) 2.48
Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing. J Cell Sci (2003) 2.46
Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis. Genes Dev (2010) 2.26
Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases. Mol Biol Cell (2003) 2.11
Altered pulmonary vascular reactivity in mice with excessive erythrocytosis. Am J Respir Crit Care Med (2003) 1.48
Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest (2016) 1.42
The glial cell response is an essential component of hypoxia-induced erythropoiesis in mice. J Clin Invest (2009) 1.40
Neuropilin 1 deficiency on CD4+Foxp3+ regulatory T cells impairs mouse melanoma growth. J Exp Med (2012) 1.38
Regulation of hypoxia-inducible factors during inflammation. Methods Enzymol (2007) 1.29
Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2. J Biol Chem (2006) 1.29
The proinflammatory cytokine interleukin 1beta and hypoxia cooperatively induce the expression of adrenomedullin in ovarian carcinoma cells through hypoxia inducible factor 1 activation. Cancer Res (2005) 1.24
Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression. Clin Exp Pharmacol Physiol (2006) 1.21
Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells. Blood (2002) 1.11
Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38. J Biol Chem (2009) 1.08
NO and TNF-alpha released from activated macrophages stabilize HIF-1alpha in resting tubular LLC-PK1 cells. Am J Physiol Cell Physiol (2002) 1.07
Identification of protein disulfide isomerase as a cardiomyocyte survival factor in ischemic cardiomyopathy. J Am Coll Cardiol (2007) 1.07
Hepatic erythropoietin gene regulation by GATA-4. J Biol Chem (2003) 1.06
Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. J Biol Chem (2009) 1.04
The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases. Cardiovasc Res (2006) 1.03
Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site. J Cell Biochem (2004) 1.00
Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha. J Biol Chem (2004) 0.99
The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis. Anesthesiology (2013) 0.99
NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum. J Biol Chem (2004) 0.98
Thrombopoietin production in wild-type and interleukin-6 knockout mice with acute inflammation. J Interferon Cytokine Res (2005) 0.98
Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling. Nucleic Acids Res (2011) 0.95
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis. Blood (2012) 0.95
Nuclear oxygen sensing: induction of endogenous prolyl-hydroxylase 2 activity by hypoxia and nitric oxide. J Biol Chem (2008) 0.95
Retracted Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC. Blood (2011) 0.94
Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia. Free Radic Res (2012) 0.94
Retracted Hypoxia-inducible factor (HIF) 1alpha accumulation and HIF target gene expression are impaired after induction of endotoxin tolerance. J Immunol (2009) 0.92
Loss of fibroblast HIF-1α accelerates tumorigenesis. Cancer Res (2012) 0.92
Oxygen Radicals as Messengers in Oxygen-Dependent Gene Expression. News Physiol Sci (2000) 0.91
A wound size-dependent effect of myeloid cell-derived vascular endothelial growth factor on wound healing. J Invest Dermatol (2010) 0.90
Reactive oxygen species modulate HIF-1 mediated PAI-1 expression: involvement of the GTPase Rac1. Thromb Haemost (2003) 0.89
Neural substrates for behaviorally conditioned immunosuppression in the rat. J Neurosci (2005) 0.89
Oxygen-sensing under the influence of nitric oxide. Cell Signal (2010) 0.89
Protein expression and promoter methylation of the candidate biomarker TCF21 in head and neck squamous cell carcinoma. Cell Oncol (Dordr) (2013) 0.89
Thyroid hormone induces hypoxia-inducible factor 1alpha gene expression through thyroid hormone receptor beta/retinoid x receptor alpha-dependent activation of hepatic leukemia factor. Endocrinology (2008) 0.88
Hemostasis and coagulation at a hematocrit level of 0.85: functional consequences of erythrocytosis. Blood (2003) 0.88
Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: prospective observational clinical and cellular studies. Anesthesiology (2013) 0.87
Aberrant mural cell recruitment to lymphatic vessels and impaired lymphatic drainage in a murine model of pulmonary fibrosis. Blood (2012) 0.87
Role of hypoxia inducible factor-1α for interferon synthesis in mouse dendritic cells. Biol Chem (2013) 0.86
Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma. Int J Colorectal Dis (2009) 0.86
Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors. Biochem Biophys Res Commun (2009) 0.85
Thrombopoietin gene expression in the developing human central nervous system. Brain Res Dev Brain Res (2003) 0.85
Myeloid hypoxia-inducible factor-1α is essential for skeletal muscle regeneration in mice. J Immunol (2013) 0.85
Optical analysis of the HIF-1 complex in living cells by FRET and FRAP. FASEB J (2006) 0.85
Thyroid hormone induces erythropoietin gene expression through augmented accumulation of hypoxia-inducible factor-1. Am J Physiol Regul Integr Comp Physiol (2004) 0.84
The HIF-1 response to simulated ischemia in mouse skeletal muscle cells neither enhances glycolysis nor prevents myotube cell death. Am J Physiol Regul Integr Comp Physiol (2007) 0.84
Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling. J Cell Sci (2012) 0.84
A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression. Haematologica (2014) 0.82
Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat. J Invest Surg (2010) 0.80
Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. Br J Haematol (2014) 0.80
Multifocal animated imaging of changes in cellular oxygen and calcium concentrations and membrane potential within the intact adult mouse carotid body ex vivo. Am J Physiol Cell Physiol (2011) 0.80
Developmental changes in the expression of transcription factors GATA-1, -2 and -3 during the onset of human medullary haematopoiesis. Br J Haematol (2002) 0.80
The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9. PLoS One (2011) 0.79
Visualization of the three-dimensional organization of hypoxia-inducible factor-1 alpha and interacting cofactors in subnuclear structures. Biol Chem (2004) 0.79
Molecular imaging: into in vivo interaction of HIF-1alpha and HIF-2alpha with ARNT. Ann N Y Acad Sci (2009) 0.79
Mitochondrial DNA: An Endogenous Trigger for Immune Paralysis. Anesthesiology (2016) 0.79
More insights into the CCN3/Connexin43 interaction complex and its role for signaling. J Cell Biochem (2010) 0.79
A cordial affair - erythropoietin and cardioprotection. Cardiovasc Res (2006) 0.78
Measurement of ROS Levels and Membrane Potential Dynamics in the Intact Carotid Body Ex Vivo. Adv Exp Med Biol (2015) 0.77
Monitoring of cellular responses to hypoxia. Methods Mol Biol (2010) 0.77
Activation of hypoxia-inducible factor 1 in skeletal muscle cells after exposure to damaged muscle cell debris. Shock (2011) 0.77
The impact of N-nitrosomelatonin as nitric oxide donor in cell culture experiments. J Pineal Res (2008) 0.77
No evidence for protective erythropoietin alpha signalling in rat hepatocytes. BMC Gastroenterol (2009) 0.77
Protection of the right ventricle from ischemia and reperfusion by preceding hypoxia. Naunyn Schmiedebergs Arch Pharmacol (2008) 0.77
Role of N-acetyl-N-nitroso-tryptophan as nitric oxide donor in the modulation of HIF-1-dependent signaling. Biol Chem (2010) 0.75
Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software. PMC Biophys (2010) 0.75
Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species. J Appl Physiol (1985) (2006) 0.75
Hypoxia induced gene expression: the specificity switch! Cell Cycle (2015) 0.75
Highlight: sensing hypoxia in the cell and the organism. Biol Chem (2013) 0.75
Retraction: Hypoxia-Inducible Factor (HIF) 1α Accumulation and HIF Target Gene Expression Are Impaired after Induction of Endotoxin Tolerance. J Immunol (2017) 0.75
Effects of recombinant human erythropoietin (rHuEPO) on tumor control in patients with cancer-induced anemia. Onkologie (2005) 0.75
Oxygen and the cell. Biol Chem (2004) 0.75
Two-photon imaging of cellular activities in oxygen sensing tissues. Microsc Microanal (2008) 0.75