Published in PLoS One on August 30, 2012
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Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma. PLoS Comput Biol (2012) 1.54
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E2F-1 is a critical modulator of cellular senescence in human cancer. Int J Mol Med (2006) 1.06
ETS1 mediates MEK1/2-dependent overexpression of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human cancer cells. PLoS One (2011) 1.05
E2F3 is a mediator of DNA damage-induced apoptosis. Mol Cell Biol (2009) 1.04
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c-Ets1 is a promising marker in epithelial ovarian cancer. Int J Mol Med (2002) 0.94
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Genome-scale screen for DNA methylation-based detection markers for ovarian cancer. PLoS One (2011) 0.87
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TSGene: a web resource for tumor suppressor genes. Nucleic Acids Res (2012) 2.90
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dmGWAS: dense module searching for genome-wide association studies in protein-protein interaction networks. Bioinformatics (2010) 2.23
Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell (2010) 2.20
Computational tools for copy number variation (CNV) detection using next-generation sequencing data: features and perspectives. BMC Bioinformatics (2013) 2.07
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Schizophrenia gene networks and pathways and their applications for novel candidate gene selection. PLoS One (2010) 1.67
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Construction of a chloroplast protein interaction network and functional mining of photosynthetic proteins in Arabidopsis thaliana. Cell Res (2008) 1.58
Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma. PLoS Comput Biol (2012) 1.54
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Epithelial cell organization suppresses Myc function by attenuating Myc expression. Cancer Res (2011) 1.44
Large-scale prediction of adverse drug reactions using chemical, biological, and phenotypic properties of drugs. J Am Med Inform Assoc (2012) 1.43
A novel microRNA and transcription factor mediated regulatory network in schizophrenia. BMC Syst Biol (2010) 1.40
VirusFinder: software for efficient and accurate detection of viruses and their integration sites in host genomes through next generation sequencing data. PLoS One (2013) 1.35
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IL-15 regulates homeostasis and terminal maturation of NKT cells. J Immunol (2011) 1.29
Application of next generation sequencing to human gene fusion detection: computational tools, features and perspectives. Brief Bioinform (2012) 1.23
A comparative study of cancer proteins in the human protein-protein interaction network. BMC Genomics (2010) 1.23
Network-assisted investigation of combined causal signals from genome-wide association studies in schizophrenia. PLoS Comput Biol (2012) 1.23
Features and trend of loss of promoter-associated CpG islands in the human and mouse genomes. Mol Biol Evol (2007) 1.23
Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer. Nucleic Acids Res (2010) 1.17
A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia. J Med Genet (2011) 1.15
Rare variants in RTEL1 are associated with familial interstitial pneumonia. Am J Respir Crit Care Med (2015) 1.15
A comprehensive network and pathway analysis of candidate genes in major depressive disorder. BMC Syst Biol (2011) 1.13
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New genomic structure for prostate cancer specific gene PCA3 within BMCC1: implications for prostate cancer detection and progression. PLoS One (2009) 1.11
Mutational spectrum in the recent human genome inferred by single nucleotide polymorphisms. Genomics (2006) 1.09
Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes. Epigenetics (2011) 1.08
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GenRev: exploring functional relevance of genes in molecular networks. Genomics (2011) 1.07
Deciphering the unique microRNA signature in human esophageal adenocarcinoma. PLoS One (2013) 1.05
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Discovering disease-specific biomarker genes for cancer diagnosis and prognosis. Technol Cancer Res Treat (2010) 1.04
ERGR: An ethanol-related gene resource. Nucleic Acids Res (2008) 1.04
Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance. Genome Res (2013) 1.03
Integrative network analysis identifies key genes and pathways in the progression of hepatitis C virus induced hepatocellular carcinoma. BMC Med Genomics (2011) 1.02
Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome. BMC Genomics (2011) 1.02
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An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies. Bioinformatics (2011) 1.01
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Synergetic regulatory networks mediated by oncogene-driven microRNAs and transcription factors in serous ovarian cancer. Mol Biosyst (2013) 0.99
A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case. BMC Syst Biol (2015) 0.99
CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome? BMC Bioinformatics (2009) 0.98
Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PLoS One (2011) 0.98
RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia. BMC Genomics (2012) 0.97
Comparative analysis of CpG islands in four fish genomes. Comp Funct Genomics (2008) 0.97
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Dynamic protein interaction modules in human hepatocellular carcinoma progression. BMC Syst Biol (2013) 0.96
Consensus rules in variant detection from next-generation sequencing data. PLoS One (2012) 0.96
The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. Schizophr Res (2009) 0.95
Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma. Cancer (2013) 0.95
Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer. BMC Syst Biol (2012) 0.95
Investigating the relationship of DNA methylation with mutation rate and allele frequency in the human genome. BMC Genomics (2012) 0.95
InPrePPI: an integrated evaluation method based on genomic context for predicting protein-protein interactions in prokaryotic genomes. BMC Bioinformatics (2007) 0.95
Network.assisted analysis to prioritize GWAS results: principles, methods and perspectives. Hum Genet (2014) 0.94
Enriched pathways for major depressive disorder identified from a genome-wide association study. Int J Neuropsychopharmacol (2012) 0.93
Prioritization and evaluation of depression candidate genes by combining multidimensional data resources. PLoS One (2011) 0.93
CNVannotator: a comprehensive annotation server for copy number variation in the human genome. PLoS One (2013) 0.93
Prioritization of epilepsy associated candidate genes by convergent analysis. PLoS One (2011) 0.92
Application of systems biology approach identifies and validates GRB2 as a risk gene for schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. Schizophr Res (2010) 0.92
Contrast features of CpG islands in the promoter and other regions in the dog genome. Genomics (2009) 0.92
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Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance. Am J Respir Cell Mol Biol (2012) 0.88
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Do cancer proteins really interact strongly in the human protein-protein interaction network? Comput Biol Chem (2011) 0.85
Searching joint association signals in CATIE schizophrenia genome-wide association studies through a refined integrative network approach. BMC Genomics (2012) 0.85
Assessing gene length biases in gene set analysis of Genome-Wide Association Studies. Int J Comput Biol Drug Des (2011) 0.85
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An evidence-based knowledgebase of pulmonary arterial hypertension to identify genes and pathways relevant to pathogenesis. Mol Biosyst (2014) 0.84
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Functional features, biological pathways, and protein interaction networks of addiction-related genes. Chem Biodivers (2010) 0.84
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