Published in Nucleic Acids Res on October 12, 2012
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Statistically identifying tumor suppressors and oncogenes from pan-cancer genome-sequencing data. Bioinformatics (2015) 0.79
Retracted Abnormal gene expression and gene fusion in lung adenocarcinoma with high-throughput RNA sequencing. Cancer Gene Ther (2014) 0.79
Identifying novel genes and chemicals related to nasopharyngeal cancer in a heterogeneous network. Sci Rep (2016) 0.79
Methylome sequencing for fibrolamellar hepatocellular carcinoma depicts distinctive features. Epigenetics (2015) 0.78
Analysis of tumor suppressor genes based on gene ontology and the KEGG pathway. PLoS One (2014) 0.78
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Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer. Carcinogenesis (2015) 0.77
dbCPG: A web resource for cancer predisposition genes. Oncotarget (2016) 0.77
Bioinformatics analysis of hepatitis C virus genotype 2a-induced human hepatocellular carcinoma in Huh7 cells. Onco Targets Ther (2016) 0.77
Notch-mediated expansion of cord blood progenitors: maintenance of transcriptional and epigenetic fidelity. Leukemia (2015) 0.76
Integrated network analysis and logistic regression modeling identify stage-specific genes in Oral Squamous Cell Carcinoma. BMC Med Genomics (2015) 0.76
CGMD: An integrated database of cancer genes and markers. Sci Rep (2015) 0.76
Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules. Proteomics Clin Appl (2015) 0.76
Gene Network Rewiring to Study Melanoma Stage Progression and Elements Essential for Driving Melanoma. PLoS One (2015) 0.76
Identifying New Candidate Genes and Chemicals Related to Prostate Cancer Using a Hybrid Network and Shortest Path Approach. Comput Math Methods Med (2015) 0.76
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Transcriptional Selectivity of Epigenetic Therapy in Cancer. Cancer Res (2016) 0.75
Bioinformatics analysis of the molecular mechanism of diffuse intrinsic pontine glioma. Oncol Lett (2016) 0.75
Opposite activation of the Hedgehog pathway in CD138+ plasma cells and CD138-CD19+ B cells identifies two subgroups of patients with multiple myeloma and different prognosis. Leukemia (2016) 0.75
Identification of Cancer Related Genes Using a Comprehensive Map of Human Gene Expression. PLoS One (2016) 0.75
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Identification of candidate genes for myeloma-induced osteocyte death based on microarray data. J Orthop Surg Res (2016) 0.75
Analysis of the molecular mechanism of osteosarcoma using a bioinformatics approach. Oncol Lett (2016) 0.75
Microarray data analysis to identify crucial genes regulated by CEBPB in human SNB19 glioma cells. World J Surg Oncol (2016) 0.75
Identification of the key genes connected with plasma cells of multiple myeloma using expression profiles. Onco Targets Ther (2015) 0.75
Screening of Tumor Suppressor Genes in Metastatic Colorectal Cancer. Biomed Res Int (2017) 0.75
Identification of differentially expressed genes in salivary adenoid cystic carcinoma cells associated with metastasis. Arch Med Sci (2016) 0.75
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Identification of mutant genes with high-frequency, high-risk, and high-expression in lung adenocarcinoma. Thorac Cancer (2014) 0.75
LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer. BMC Bioinformatics (2016) 0.75
Molecular mechanisms for alcoholic hepatitis based on analysis of gene expression profile. Hepat Mon (2015) 0.75
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Potential molecular characteristics in situ in response to repetitive UVB irradiation. Diagn Pathol (2016) 0.75
GCGene: a gene resource for gastric cancer with literature evidence. Oncotarget (2016) 0.75
Development of prognostic signatures for intermediate-risk papillary thyroid cancer. BMC Cancer (2016) 0.75
BLAT2DOLite: An Online System for Identifying Significant Relationships between Genetic Sequences and Diseases. PLoS One (2016) 0.75
Role of NSC319726 in ovarian cancer based on the bioinformatics analyses. Onco Targets Ther (2015) 0.75
OncoScape: Exploring the cancer aberration landscape by genomic data fusion. Sci Rep (2016) 0.75
Identification of genes associated with methotrexate resistance in methotrexate-resistant osteosarcoma cell lines. J Orthop Surg Res (2015) 0.75
Identification of colorectal cancer-restricted microRNAs and their target genes based on high-throughput sequencing data. Onco Targets Ther (2016) 0.75
piggyBac mediates efficient in vivo CRISPR library screening for tumorigenesis in mice. Proc Natl Acad Sci U S A (2017) 0.75
REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer. Sci Rep (2016) 0.75
Whole-Genome DNA Methylation Profiling Identifies Epigenetic Signatures of Uterine Carcinosarcoma. Neoplasia (2017) 0.75
Bioinformatics analyses of differentially expressed genes associated with bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma. Onco Targets Ther (2015) 0.75
Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs. BMC Genomics (2016) 0.75
Identification of novel thyroid cancer-related genes and chemicals using shortest path algorithm. Biomed Res Int (2015) 0.75
Gene expression profile analysis of ventilator-associated pneumonia. Mol Med Rep (2015) 0.75
Identification of molecular characteristics induced by radiotherapy in rectal cancer based on microarray data. Oncol Lett (2017) 0.75
Time course analysis based on gene expression profile and identification of target molecules for colorectal cancer. Cancer Cell Int (2016) 0.75
Characterization and Comparative Expression Profiling of Browning Response in Medinilla formosana after Cutting. Front Plant Sci (2016) 0.75
Cluster Analysis of Tumor Suppressor Genes in Canine Leukocytes Identifies Activation State. Bioinform Biol Insights (2016) 0.75
Driver gene classification reveals a substantial overrepresentation of tumor suppressors among very large chromatin-regulating proteins. Sci Rep (2016) 0.75
A gene browser of colorectal cancer with literature evidence and pre-computed regulatory information to identify key tumor suppressors and oncogenes. Sci Rep (2016) 0.75
Inhibition of DNA and Histone Methylation by 5-Aza-2'-Deoxycytidine (Decitabine) and 3-Deazaneplanocin-A on Antineoplastic Action and Gene Expression in Myeloid Leukemic Cells. Front Oncol (2017) 0.75
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Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature (2008) 75.40
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Integrated genomic analyses of ovarian carcinoma. Nature (2011) 47.72
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell (2010) 39.09
Comprehensive molecular characterization of human colon and rectal cancer. Nature (2012) 34.13
The impact of microRNAs on protein output. Nature (2008) 32.39
Widespread changes in protein synthesis induced by microRNAs. Nature (2008) 31.44
KEGG for integration and interpretation of large-scale molecular data sets. Nucleic Acids Res (2011) 30.20
miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res (2010) 25.85
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res (2010) 25.55
TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res (2006) 22.20
Reorganizing the protein space at the Universal Protein Resource (UniProt). Nucleic Acids Res (2011) 18.50
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PANTHER version 7: improved phylogenetic trees, orthologs and collaboration with the Gene Ontology Consortium. Nucleic Acids Res (2009) 9.14
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Annotating the human genome with Disease Ontology. BMC Genomics (2009) 4.71
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Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma. PLoS Comput Biol (2012) 1.54
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Retracted Copy number variations and cancer susceptibility. Curr Opin Oncol (2010) 1.24
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Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma. PLoS Comput Biol (2012) 1.54
A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case. Bioinformatics (2009) 1.50
Epithelial cell organization suppresses Myc function by attenuating Myc expression. Cancer Res (2011) 1.44
Large-scale prediction of adverse drug reactions using chemical, biological, and phenotypic properties of drugs. J Am Med Inform Assoc (2012) 1.43
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IL-15 regulates homeostasis and terminal maturation of NKT cells. J Immunol (2011) 1.29
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A comparative study of cancer proteins in the human protein-protein interaction network. BMC Genomics (2010) 1.23
Network-assisted investigation of combined causal signals from genome-wide association studies in schizophrenia. PLoS Comput Biol (2012) 1.23
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Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer. Nucleic Acids Res (2010) 1.17
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Rare variants in RTEL1 are associated with familial interstitial pneumonia. Am J Respir Crit Care Med (2015) 1.15
A comprehensive network and pathway analysis of candidate genes in major depressive disorder. BMC Syst Biol (2011) 1.13
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New genomic structure for prostate cancer specific gene PCA3 within BMCC1: implications for prostate cancer detection and progression. PLoS One (2009) 1.11
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Conservation and divergence of DNA methylation in eukaryotes: new insights from single base-resolution DNA methylomes. Epigenetics (2011) 1.08
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Deciphering the unique microRNA signature in human esophageal adenocarcinoma. PLoS One (2013) 1.05
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Discovering disease-specific biomarker genes for cancer diagnosis and prognosis. Technol Cancer Res Treat (2010) 1.04
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Next-generation sequencing of paired tyrosine kinase inhibitor-sensitive and -resistant EGFR mutant lung cancer cell lines identifies spectrum of DNA changes associated with drug resistance. Genome Res (2013) 1.03
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Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome. BMC Genomics (2011) 1.02
Beyond histology: translating tumor genotypes into clinically effective targeted therapies. Clin Cancer Res (2014) 1.01
An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies. Bioinformatics (2011) 1.01
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Synergetic regulatory networks mediated by oncogene-driven microRNAs and transcription factors in serous ovarian cancer. Mol Biosyst (2013) 0.99
A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case. BMC Syst Biol (2015) 0.99
CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome? BMC Bioinformatics (2009) 0.98
Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PLoS One (2011) 0.98
RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia. BMC Genomics (2012) 0.97
Methylation-dependent transition rates are dependent on local sequence lengths and genomic regions. Mol Biol Evol (2006) 0.97
Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome. BMC Genomics (2006) 0.97
Comparative analysis of CpG islands in four fish genomes. Comp Funct Genomics (2008) 0.97
Distinct and competitive regulatory patterns of tumor suppressor genes and oncogenes in ovarian cancer. PLoS One (2012) 0.96
Dynamic protein interaction modules in human hepatocellular carcinoma progression. BMC Syst Biol (2013) 0.96
Consensus rules in variant detection from next-generation sequencing data. PLoS One (2012) 0.96
The dystrobrevin binding protein 1 (DTNBP1) gene is associated with schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. Schizophr Res (2009) 0.95
Investigating the relationship of DNA methylation with mutation rate and allele frequency in the human genome. BMC Genomics (2012) 0.95
Integrative pathway analysis of genome-wide association studies and gene expression data in prostate cancer. BMC Syst Biol (2012) 0.95
Gastric adenocarcinoma has a unique microRNA signature not present in esophageal adenocarcinoma. Cancer (2013) 0.95
InPrePPI: an integrated evaluation method based on genomic context for predicting protein-protein interactions in prokaryotic genomes. BMC Bioinformatics (2007) 0.95
Network.assisted analysis to prioritize GWAS results: principles, methods and perspectives. Hum Genet (2014) 0.94
Enriched pathways for major depressive disorder identified from a genome-wide association study. Int J Neuropsychopharmacol (2012) 0.93
Prioritization and evaluation of depression candidate genes by combining multidimensional data resources. PLoS One (2011) 0.93
CNVannotator: a comprehensive annotation server for copy number variation in the human genome. PLoS One (2013) 0.93
Contrast features of CpG islands in the promoter and other regions in the dog genome. Genomics (2009) 0.92
Prioritization of epilepsy associated candidate genes by convergent analysis. PLoS One (2011) 0.92
Application of systems biology approach identifies and validates GRB2 as a risk gene for schizophrenia in the Irish Case Control Study of Schizophrenia (ICCSS) sample. Schizophr Res (2010) 0.92
Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells. Int J Radiat Oncol Biol Phys (2011) 0.92
Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes. Brief Bioinform (2015) 0.91
Education, collaboration, and innovation: intelligent biology and medicine in the era of big data. BMC Genomics (2015) 0.90
DTome: a web-based tool for drug-target interactome construction. BMC Bioinformatics (2012) 0.89
Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance. Am J Respir Cell Mol Biol (2012) 0.88
Features of methylation and gene expression in the promoter-associated CpG islands using human methylome data. Comp Funct Genomics (2012) 0.87
Ranking gene-drug relationships in biomedical literature using Latent Dirichlet Allocation. Pac Symp Biocomput (2012) 0.86
Apoptotic engulfment pathway and schizophrenia. PLoS One (2009) 0.86
Intravenous glial growth factor 2 (GGF2) isoform of neuregulin-1β improves left ventricular function, gene and protein expression in rats after myocardial infarction. PLoS One (2013) 0.86
Do cancer proteins really interact strongly in the human protein-protein interaction network? Comput Biol Chem (2011) 0.85
Assessing gene length biases in gene set analysis of Genome-Wide Association Studies. Int J Comput Biol Drug Des (2011) 0.85
Searching joint association signals in CATIE schizophrenia genome-wide association studies through a refined integrative network approach. BMC Genomics (2012) 0.85
MSEA: detection and quantification of mutation hotspots through mutation set enrichment analysis. Genome Biol (2014) 0.85
An evidence-based knowledgebase of pulmonary arterial hypertension to identify genes and pathways relevant to pathogenesis. Mol Biosyst (2014) 0.84
SNPNB: analyzing neighboring-nucleotide biases on single nucleotide polymorphisms (SNPs). Bioinformatics (2005) 0.84
Functional features, biological pathways, and protein interaction networks of addiction-related genes. Chem Biodivers (2010) 0.84
Prioritization and association analysis of murine-derived candidate genes in anxiety-spectrum disorders. Biol Psychiatry (2011) 0.83
Adaptive evolution of MRGX2, a human sensory neuron specific gene involved in nociception. Gene (2005) 0.83