Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation.

PubWeight™: 1.90‹?› | Rank: Top 3%

🔗 View Article (PMC 3434182)

Published in PLoS One on September 05, 2012

Authors

Benoit Chassaing1, Gayathri Srinivasan, Maria A Delgado, Andrew N Young, Andrew T Gewirtz, Matam Vijay-Kumar

Author Affiliations

1: Department of Biology, Center for Inflammation, Immunity and Infection, Georgia State University, Atlanta, Georgia, United States of America.

Associated clinical trials:

Pilot of a Prebiotic and Probiotic Trial in Young Infants With Severe Acute Malnutrition | NCT03666572

Articles citing this

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Nature (2015) 3.06

AIEC pathobiont instigates chronic colitis in susceptible hosts by altering microbiota composition. Gut (2013) 2.08

Antibiotic treatment suppresses rotavirus infection and enhances specific humoral immunity. J Infect Dis (2014) 1.60

Dextran sulfate sodium (DSS)-induced colitis in mice. Curr Protoc Immunol (2014) 1.52

Maternal IgG and IgA Antibodies Dampen Mucosal T Helper Cell Responses in Early Life. Cell (2016) 1.50

Tissue adaptation of regulatory and intraepithelial CD4⁺ T cells controls gut inflammation. Science (2016) 1.49

CD40-signalling abrogates induction of RORγt(+) Treg cells by intestinal CD103(+) DCs and causes fatal colitis. Nat Commun (2017) 1.38

Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation. Environ Health Perspect (2015) 1.34

Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota to prevent low-grade inflammation and metabolic syndrome in mice. Gastroenterology (2014) 1.31

Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest (2015) 1.13

Dextran sodium sulfate inhibits the activities of both polymerase and reverse transcriptase: lithium chloride purification, a rapid and efficient technique to purify RNA. BMC Res Notes (2013) 1.05

Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis. Cell Mol Gastroenterol Hepatol (2016) 1.01

Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nat Commun (2015) 1.00

Inhibition of Interleukin-10 Signaling Induces Microbiota-dependent Chronic Colitis in Apolipoprotein E Deficient Mice. Inflamm Bowel Dis (2016) 0.94

Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer. Lab Invest (2014) 0.91

Lipocalin 2 alleviates iron toxicity by facilitating hypoferremia of inflammation and limiting catalytic iron generation. Biometals (2016) 0.91

Lack of soluble fiber drives diet-induced adiposity in mice. Am J Physiol Gastrointest Liver Physiol (2015) 0.89

The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. J Biol Chem (2014) 0.87

Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and lipopolysaccharide-induced TLR4 signalling. J Physiol (2017) 0.87

Innate immune detection of flagellin positively and negatively regulates salmonella infection. PLoS One (2013) 0.86

Expression of the Blood-Group-Related Gene B4galnt2 Alters Susceptibility to Salmonella Infection. PLoS Pathog (2015) 0.86

Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2. Clin Exp Immunol (2013) 0.85

Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation. J Exp Med (2016) 0.85

Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens. Eur J Immunol (2015) 0.82

Proneness of TLR5 deficient mice to develop colitis is microbiota dependent. Gut Microbes (2015) 0.81

Hypoxia-inducible factor 1 in dendritic cells is crucial for the activation of protective regulatory T cells in murine colitis. Mucosal Immunol (2015) 0.81

Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice. Environ Sci Technol (2015) 0.80

The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases. Biomarkers (2015) 0.80

Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer. Biomaterials (2016) 0.80

Gene expression profiling in necrotizing enterocolitis reveals pathways common to those reported in Crohn's disease. BMC Med Genomics (2016) 0.78

Comparisons between myeloperoxidase, lactoferrin, calprotectin and lipocalin-2, as fecal biomarkers of intestinal inflammation in malnourished children. J Transl Sci (2016) 0.78

Chronic Repression of mTOR Complex 2 Induces Changes in the Gut Microbiota of Diet-induced Obese Mice. Sci Rep (2016) 0.77

Longitudinal study of circulating protein biomarkers in inflammatory bowel disease. J Proteomics (2014) 0.77

Biomarkers of Inflammatory Bowel Disease: From Classical Laboratory Tools to Personalized Medicine. Inflamm Bowel Dis (2015) 0.76

Escherichia coli heme oxygenase modulates host innate immune responses. Microbiol Immunol (2015) 0.76

Ron receptor-dependent gene regulation of Kupffer cells during endotoxemia. Hepatobiliary Pancreat Dis Int (2014) 0.76

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation. Nat Biotechnol (2017) 0.76

Characterization of Changes in Global Genes Expression in the Distal Colon of Loperamide-Induced Constipation SD Rats in Response to the Laxative Effects of Liriope platyphylla. PLoS One (2015) 0.75

Homeostasis of the Gut Barrier and Potential Biomarkers. Am J Physiol Gastrointest Liver Physiol (2016) 0.75

Comparative effects of α2δ-1 ligands in mouse models of colonic hypersensitivity. World J Gastroenterol (2016) 0.75

Minimally invasive screening for colitis using attenuated total internal reflectance fourier transform infrared spectroscopy. J Biophotonics (2016) 0.75

Siderophore-mediated iron acquisition and modulation of host-bacterial interactions. Free Radic Biol Med (2016) 0.75

Adherent-Invasive Escherichia coli Production of Cellulose Influences Iron-Induced Bacterial Aggregation, Phagocytosis, and Induction of Colitis. Infect Immun (2015) 0.75

Chemical and pathogen-induced inflammation disrupt the murine intestinal microbiome. Microbiome (2017) 0.75

Dietary Emulsifier-Induced Low-Grade Inflammation Promotes Colon Carcinogenesis. Cancer Res (2016) 0.75

Ectopic Expression of Innate Immune Protein, Lipocalin-2, in Lactococcus lactis Protects Against Gut and Environmental Stressors. Inflamm Bowel Dis (2017) 0.75

The Effect of Cigarette Smoke Exposure on the Development of Inflammation in Lungs, Gut and Joints of TNFΔARE Mice. PLoS One (2015) 0.75

Iron Homeostasis and Inflammatory Status in Mice Deficient for the Cystic Fibrosis Transmembrane Regulator. PLoS One (2015) 0.75

Cosmc is an X-linked inflammatory bowel disease risk gene that spatially regulates gut microbiota and contributes to sex-specific risk. Proc Natl Acad Sci U S A (2016) 0.75

Lipocalin 2 prevents intestinal inflammation by enhancing phagocytic bacterial clearance in macrophages. Sci Rep (2016) 0.75

Modulation of urinary siderophores by the diet, gut microbiota and inflammation in mice. J Nutr Biochem (2016) 0.75

Deficiency of stearoyl-CoA desaturase-1 aggravates colitogenic potential of adoptively transferred effector T cells. Am J Physiol Gastrointest Liver Physiol (2016) 0.75

Food Additive P-80 Impacts Mouse Gut Microbiota Promoting Intestinal Inflammation, Obesity and Liver Dysfunction. SOJ Microbiol Infect Dis (2016) 0.75

Isothiocyanate-enriched moringa seed extract alleviates ulcerative colitis symptoms in mice. PLoS One (2017) 0.75

Ileocolic resection is associated with increased susceptibility to injury in a murine model of colitis. PLoS One (2017) 0.75

Dietary Salt Exacerbates Experimental Colitis. J Immunol (2017) 0.75

Intestinal IgA as a modulator of the gut microbiota. Gut Microbes (2017) 0.75

Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis. PLoS Pathog (2017) 0.75

Integrated Analysis of Biopsies from Inflammatory Bowel Disease Patients Identifies SAA1 as a Link Between Mucosal Microbes with TH17 and TH22 Cells. Inflamm Bowel Dis (2017) 0.75

Articles cited by this

Interleukin-10-deficient mice develop chronic enterocolitis. Cell (1993) 22.57

Unravelling the pathogenesis of inflammatory bowel disease. Nature (2007) 18.52

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature (2011) 13.53

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science (2010) 12.54

Lipocalin-2 resistance confers an advantage to Salmonella enterica serotype Typhimurium for growth and survival in the inflamed intestine. Cell Host Microbe (2009) 4.20

Deletion of TLR5 results in spontaneous colitis in mice. J Clin Invest (2007) 4.18

Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans. Clin Chem (2006) 3.44

The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance. Diabetes (2007) 3.42

Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J Clin Invest (2005) 3.36

The Ngal reporter mouse detects the response of the kidney to injury in real time. Nat Med (2011) 3.20

Identification of common transcriptional regulatory elements in interleukin-17 target genes. J Biol Chem (2006) 2.65

Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice. Cell Host Microbe (2012) 2.48

The commensal microbiota and enteropathogens in the pathogenesis of inflammatory bowel diseases. Gastroenterology (2011) 2.41

Evaluation of urine biomarkers of kidney injury in polycystic kidney disease. Kidney Int (2012) 2.39

The utility of biomarkers in the diagnosis and therapy of inflammatory bowel disease. Gastroenterology (2011) 2.18

Recent insights into the genetics of inflammatory bowel disease. Gastroenterology (2011) 2.12

Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse. Biochim Biophys Acta (2000) 2.06

Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology (2005) 2.03

The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages. Mol Endocrinol (2008) 2.00

IL-1beta-specific up-regulation of neutrophil gelatinase-associated lipocalin is controlled by IkappaB-zeta. J Immunol (2006) 1.87

Flagellin suppresses epithelial apoptosis and limits disease during enteric infection. Am J Pathol (2006) 1.77

Activation of toll-like receptor 3 protects against DSS-induced acute colitis. Inflamm Bowel Dis (2007) 1.57

Identification by microsequencing of lipopolysaccharide-induced proteins secreted by mouse macrophages. J Immunol (1993) 1.37

Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans. J Mol Med (Berl) (2009) 1.33

Colorectal cancer and dysplasia in inflammatory bowel disease. World J Gastroenterol (2008) 1.30

Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis. J Immunol (2012) 1.22

Rectal dialysate and fecal concentrations of neutrophil gelatinase-associated lipocalin, interleukin-8, and tumor necrosis factor-alpha in ulcerative colitis. Am J Gastroenterol (1999) 1.16

Effects of mouse and human lipocalin homologues 24p3/lcn2 and neutrophil gelatinase-associated lipocalin on gastrointestinal mucosal integrity and repair. Gastroenterology (2006) 1.10

Lipocalins and insulin resistance: etiological role of retinol-binding protein 4 and lipocalin-2? Clin Chem (2007) 1.06

Faecal calprotectin: a marker of inflammation throughout the intestinal tract. Eur J Gastroenterol Hepatol (2002) 1.04

Fecal HMGB1 is a novel marker of intestinal mucosal inflammation in pediatric inflammatory bowel disease. Am J Gastroenterol (2011) 0.97

A non-invasive quantitative assay to measure murine intestinal inflammation using the neutrophil marker lactoferrin. J Immunol Methods (2006) 0.93

Articles by these authors

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science (2010) 12.54

In vivo tumor targeting and spectroscopic detection with surface-enhanced Raman nanoparticle tags. Nat Biotechnol (2007) 7.33

Deletion of TLR5 results in spontaneous colitis in mice. J Clin Invest (2007) 4.18

Innate and adaptive immunity interact to quench microbiome flagellar motility in the gut. Cell Host Microbe (2013) 3.05

Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice. Cell Host Microbe (2012) 2.48

Flagellin is the major proinflammatory determinant of enteropathogenic Salmonella. J Immunol (2003) 2.43

Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity. Nat Cell Biol (2010) 2.38

Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis. Gut (2013) 2.32

Bacterial flagellin is an effective adjuvant for CD4+ T cells in vivo. J Immunol (2002) 2.22

Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. J Immunol (2008) 2.07

Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. J Clin Invest (2009) 2.06

Dysregulation of inflammatory responses by chronic circadian disruption. J Immunol (2010) 2.05

Increased number of coagulation products in relationship to red blood cell products transfused improves mortality in trauma patients. Transfusion (2009) 2.04

Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology (2005) 2.03

Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis. J Immunol (2002) 1.95

Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease. Am J Physiol Gastrointest Liver Physiol (2006) 1.83

Primary thyroid-like follicular carcinoma of the kidney: report of 6 cases of a histologically distinctive adult renal epithelial neoplasm. Am J Surg Pathol (2009) 1.78

Flagellin suppresses epithelial apoptosis and limits disease during enteric infection. Am J Pathol (2006) 1.77

In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells. Cancer Res (2009) 1.67

Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia. Proc Natl Acad Sci U S A (2004) 1.63

Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma. Am J Surg Pathol (2009) 1.63

Chromophobe renal cell carcinoma: histomorphologic characteristics and evaluation of conventional pathologic prognostic parameters in 145 cases. Am J Surg Pathol (2008) 1.60

Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques. J Clin Invest (2010) 1.59

Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. Am J Surg Pathol (2006) 1.58

Activation of toll-like receptor 3 protects against DSS-induced acute colitis. Inflamm Bowel Dis (2007) 1.57

A novel tumor grading scheme for chromophobe renal cell carcinoma: prognostic utility and comparison with Fuhrman nuclear grade. Am J Surg Pathol (2010) 1.55

Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice. J Immunol (2006) 1.54

Immunohistochemical analysis of mucinous tubular and spindle cell carcinoma and papillary renal cell carcinoma of the kidney: significant immunophenotypic overlap warrants diagnostic caution. Am J Surg Pathol (2006) 1.52

Gut microbial products regulate murine gastrointestinal motility via Toll-like receptor 4 signaling. Gastroenterology (2012) 1.52

Molecular classification of renal tumors by gene expression profiling. J Mol Diagn (2005) 1.52

Dextran sulfate sodium (DSS)-induced colitis in mice. Curr Protoc Immunol (2014) 1.52

TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression. J Immunol (2006) 1.50

A2B adenosine receptor gene deletion attenuates murine colitis. Gastroenterology (2008) 1.49

Flagellin/TLR5 responses in epithelia reveal intertwined activation of inflammatory and apoptotic pathways. Am J Physiol Gastrointest Liver Physiol (2005) 1.49

Humoral immune response to flagellin requires T cells and activation of innate immunity. J Immunol (2006) 1.45

IL-6 induces NF-kappa B activation in the intestinal epithelia. J Immunol (2003) 1.42

Elevated flagellin-specific immunoglobulins in Crohn's disease. Am J Physiol Gastrointest Liver Physiol (2004) 1.41

Shanthi V. Sitaraman, MD, PhD: physician, scientist, educator, and humanitarian. Gastroenterology (2011) 1.39

Hemoglobinopathies and clinical laboratory testing. MLO Med Lab Obs (2009) 1.39

Toll-like receptor-gut microbiota interactions: perturb at your own risk! Annu Rev Physiol (2011) 1.38

In"sight" into immune blindness: Helicobacter pylori-induced gastritis requires T cells primed in the small intestine Peyer's patches. Gastroenterology (2007) 1.38

TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism. Am J Physiol Gastrointest Liver Physiol (2003) 1.38

Toll-like receptors 4 and 5 induce distinct types of vasculitis. Circ Res (2009) 1.37

TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin. Eur J Immunol (2010) 1.37

Toll-like receptor 5-deficient mice have dysregulated intestinal gene expression and nonspecific resistance to Salmonella-induced typhoid-like disease. Infect Immun (2008) 1.37

The rate of bloodstream infection is high in infants with short bowel syndrome: relationship with small bowel bacterial overgrowth, enteral feeding, and inflammatory and immune responses. J Pediatr (2010) 1.36

Angiogenic and lymphangiogenic microvessel density in breast carcinoma: correlation with clinicopathologic parameters and VEGF-family gene expression. Mod Pathol (2005) 1.34

Beta2-microglobulin promotes the growth of human renal cell carcinoma through the activation of the protein kinase A, cyclic AMP-responsive element-binding protein, and vascular endothelial growth factor axis. Clin Cancer Res (2006) 1.34

Molecular mapping of tumor heterogeneity on clinical tissue specimens with multiplexed quantum dots. ACS Nano (2010) 1.31

Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis. Am J Physiol Gastrointest Liver Physiol (2009) 1.31

Both radioresistant and hemopoietic cells promote innate and adaptive immune responses to flagellin. J Immunol (2008) 1.30

Latent cytomegalovirus infection exacerbates experimental colitis. Am J Pathol (2009) 1.30

Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases. Proc Natl Acad Sci U S A (2011) 1.28

Microbiota-liver axis in hepatic disease. Hepatology (2013) 1.27

Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis. J Immunol (2006) 1.25

Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis. Gut (2011) 1.25

Loss of HOXC6 expression induces apoptosis in prostate cancer cells. Oncogene (2005) 1.23

Detectable serum flagellin and lipopolysaccharide and upregulated anti-flagellin and lipopolysaccharide immunoglobulins in human short bowel syndrome. Am J Physiol Regul Integr Comp Physiol (2007) 1.23

Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis. J Immunol (2012) 1.22

Cancer-specific loss of beta-defensin 1 in renal and prostatic carcinomas. Lab Invest (2003) 1.22

The Salmonella typhimurium flagellar basal body protein FliE is required for flagellin production and to induce a proinflammatory response in epithelial cells. J Biol Chem (2002) 1.22

Identification and characterization of a tRNA decoding the rare AUA codon in Haloarcula marismortui. RNA (2007) 1.19

Induction of adaptive immunity by flagellin does not require robust activation of innate immunity. Eur J Immunol (2009) 1.19

Semiconductor quantum dots for bioimaging and biodiagnostic applications. Annu Rev Anal Chem (Palo Alto Calif) (2013) 1.18

Secretion of IL-2 and IFN-gamma, but not IL-4, by antigen-specific T cells requires extracellular ATP. J Immunol (2003) 1.15

Prohibitin is a novel regulator of antioxidant response that attenuates colonic inflammation in mice. Gastroenterology (2009) 1.15

Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway. J Cell Sci (2004) 1.15

Polarized fibronectin secretion induced by adenosine regulates bacterial-epithelial interaction in human intestinal epithelial cells. Biochem J (2004) 1.11

Toll like receptor-5: protecting the gut from enteric microbes. Semin Immunopathol (2007) 1.10

Intestinal epithelial cell regulation of mucosal inflammation. Immunol Res (2004) 1.08

Flagellin administration protects gut mucosal tissue from irradiation-induced apoptosis via MKP-7 activity. Gut (2011) 1.05

Identification of proinflammatory flagellin proteins in supernatants of Vibrio cholerae O1 by proteomics analysis. Mol Cell Proteomics (2006) 1.03

Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-associated cancer. Cancer Res (2010) 1.03

Gut microbiota, low-grade inflammation, and metabolic syndrome. Toxicol Pathol (2013) 1.02

Automated classification of renal cell carcinoma subtypes using scale invariant feature transform. Conf Proc IEEE Eng Med Biol Soc (2009) 1.02

Claudin-7 and claudin-8: immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma. Hum Pathol (2008) 1.02

Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus. J Immunol (2005) 1.02

Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation. Gastroenterology (2007) 1.01

Comparison of gene expression profiles in tubulocystic carcinoma and collecting duct carcinoma of the kidney. Am J Surg Pathol (2009) 1.01

Epithelial-derived fibronectin expression, signaling, and function in intestinal inflammation. J Biol Chem (2007) 1.00

Toll-like receptor 5-dependent regulation of inflammation in systemic Salmonella enterica Serovar typhimurium infection. Infect Immun (2009) 0.97

Adenosine 2B receptor expression is post-transcriptionally regulated by microRNA. J Biol Chem (2010) 0.97

Automated Renal Cell Carcinoma Subtype Classification Using Morphological, Textural and Wavelets Based Features. J Signal Process Syst (2008) 0.97

Paneth cell cryptdins act in vitro as apical paracrine regulators of the innate inflammatory response. J Biol Chem (2004) 0.96

caCORRECT2: Improving the accuracy and reliability of microarray data in the presence of artifacts. BMC Bioinformatics (2011) 0.96

Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling. Arch Pathol Lab Med (2007) 0.95

Inhibition of Interleukin-10 Signaling Induces Microbiota-dependent Chronic Colitis in Apolipoprotein E Deficient Mice. Inflamm Bowel Dis (2016) 0.94

Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunity. J Immunol (2011) 0.93

Expression analysis of kidney-specific cadherin in a wide spectrum of traditional and newly recognized renal epithelial neoplasms: diagnostic and histogenetic implications. Am J Surg Pathol (2007) 0.93