Published in Development on October 24, 2012
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Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength. J Cell Biol (2014) 1.07
Disulfide bond requirements for active Wnt ligands. J Biol Chem (2014) 0.94
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Overexpression of microRNA-1 promotes cardiomyocyte commitment from human cardiovascular progenitors via suppressing WNT and FGF signaling pathways. J Mol Cell Cardiol (2013) 0.90
Superoxide Dismutase 1 In Vivo Ameliorates Maternal Diabetes Mellitus-Induced Apoptosis and Heart Defects Through Restoration of Impaired Wnt Signaling. Circ Cardiovasc Genet (2015) 0.90
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Wnt and planar cell polarity signaling in cystic renal disease. Organogenesis (2013) 0.86
Mapping the dynamic expression of Wnt11 and the lineage contribution of Wnt11-expressing cells during early mouse development. Dev Biol (2014) 0.82
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Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations. Mol Genet Genomic Med (2013) 0.82
Activation of the Wnt/planar cell polarity pathway is required for pericyte recruitment during pulmonary angiogenesis. Am J Pathol (2014) 0.80
GATA2 regulates Wnt signaling to promote primitive red blood cell fate. Dev Biol (2015) 0.78
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Wnt ligands from the embryonic surface ectoderm regulate 'bimetallic strip' optic cup morphogenesis in mouse. Development (2015) 0.77
RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome. J Clin Invest (2015) 0.77
Formation of a "Pre-mouth Array" from the Extreme Anterior Domain Is Directed by Neural Crest and Wnt/PCP Signaling. Cell Rep (2016) 0.76
Determinants of Orofacial Clefting I: Effects of 5-Aza-2(/)-deoxycytidine on Cellular Processes and Gene Expression during Development of the First Branchial Arch. Reprod Toxicol (2016) 0.76
Integrated live imaging and molecular profiling of embryoid bodies reveals a synchronized progression of early differentiation. Sci Rep (2016) 0.75
A mutation in FRIZZLED2 impairs Wnt signaling and causes autosomal dominant omodysplasia. Hum Mol Genet (2015) 0.75
Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development: possible role in convergent extension. PLoS One (2015) 0.75
The Intracellular Loop 2 F328S Frizzled-4 Mutation Implicated in Familial Exudative Vitreoretinopathy Impairs Dishevelled Recruitment. J Mol Signal (2015) 0.75
Inhibition of p300 histone acetyltransferase activity in palate mesenchyme cells attenuates Wnt signaling via aberrant E-cadherin expression. Exp Cell Res (2016) 0.75
Planar cell polarity (PCP) proteins and spermatogenesis. Semin Cell Dev Biol (2016) 0.75
Frizzled-4 C-terminus Distal to KTXXXW Motif is Essential for Normal Dishevelled Recruitment and Norrin-stimulated Activation of Lef/Tcf-dependent Transcriptional Activation. J Mol Signal (2016) 0.75
Loss of the Wnt receptor Frizzled7 in the gastric epithelium is deleterious and triggers rapid repopulation in vivo. Dis Model Mech (2017) 0.75
Myeloid Wnt ligands are required for normal development of dermal lymphatic vasculature. PLoS One (2017) 0.75
Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families. FASEB J (2017) 0.75
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Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol (2006) 7.36
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Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science (2003) 4.18
The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes Cells (2003) 4.11
Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev (1994) 3.77
Mutations in VANGL1 associated with neural-tube defects. N Engl J Med (2007) 3.58
Nuclear envelope budding enables large ribonucleoprotein particle export during synaptic Wnt signaling. Cell (2012) 3.50
Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat Genet (2001) 3.47
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J Neurosci (2006) 3.36
Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr Biol (2003) 3.31
Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis. Nature (2002) 3.31
Monoclonal antibodies to rhodopsin: characterization, cross-reactivity, and application as structural probes. Biochemistry (1983) 3.30
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol (2008) 3.07
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development (2006) 2.96
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Frizzled-7 signalling controls tissue separation during Xenopus gastrulation. Nature (2001) 2.92
Wnt5a functions in planar cell polarity regulation in mice. Dev Biol (2007) 2.85
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell (2009) 2.63
Frizzled6 controls hair patterning in mice. Proc Natl Acad Sci U S A (2004) 2.54
Wingless signaling at synapses is through cleavage and nuclear import of receptor DFrizzled2. Science (2005) 2.53
The Wnt co-receptors Lrp5 and Lrp6 are essential for gastrulation in mice. Development (2004) 2.45
Systematic mapping of genetic interaction networks. Annu Rev Genet (2009) 2.43
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet (2008) 2.29
Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Hum Mol Genet (2001) 2.28
Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning. Nature (2010) 2.23
Frizzled-3 is required for the development of major fiber tracts in the rostral CNS. J Neurosci (2002) 2.23
The prevalence of congenital anomalies in Europe. Adv Exp Med Biol (2010) 1.99
Wnt5a regulates distinct signalling pathways by binding to Frizzled2. EMBO J (2009) 1.97
Epidemiologic and genetic aspects of spina bifida and other neural tube defects. Dev Disabil Res Rev (2010) 1.96
Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proc Natl Acad Sci U S A (2008) 1.90
Wnt3a links left-right determination with segmentation and anteroposterior axis elongation. Development (2005) 1.76
Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development. Development (2008) 1.74
Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity. Dev Cell (2011) 1.64
Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo. Dev Biol (2011) 1.59
Genetic factors in non-syndromic congenital heart malformations. Clin Genet (2010) 1.43
Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate. Hum Mol Genet (2008) 1.39
Novel mutations in VANGL1 in neural tube defects. Hum Mutat (2009) 1.37
Lrp6-mediated canonical Wnt signaling is required for lip formation and fusion. Development (2009) 1.37
Order from disorder: Self-organization in mammalian hair patterning. Proc Natl Acad Sci U S A (2006) 1.37
Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis. Proc Natl Acad Sci U S A (2012) 1.36
Rescue of a Wnt mutation by an activated form of LEF-1: regulation of maintenance but not initiation of Brachyury expression. Proc Natl Acad Sci U S A (2001) 1.35
Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements. J Cell Biol (2008) 1.31
Wnt5a is required for cardiac outflow tract septation in mice. Pediatr Res (2007) 1.27
Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes. Development (2010) 1.26
Contribution of VANGL2 mutations to isolated neural tube defects. Clin Genet (2010) 1.23
Comparison of phenotypes between different vangl2 mutants demonstrates dominant effects of the Looptail mutation during hair cell development. PLoS One (2012) 1.22
Risk of oral clefts in twins. Epidemiology (2011) 1.18
Mutations in the planar cell polarity genes CELSR1 and SCRIB are associated with the severe neural tube defect craniorachischisis. Hum Mutat (2011) 1.06
Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. Hum Mol Genet (2011) 1.04
Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant. Circ Res (2001) 1.04
Studies with Wnt genes and nonsyndromic cleft lip and palate. Birth Defects Res A Clin Mol Teratol (2010) 1.02
Genotype and haplotype analysis of WNT genes in non-syndromic cleft lip with or without cleft palate. Eur J Oral Sci (2012) 1.00
Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney. Development (2011) 0.96
Cardiac neural crest and outflow tract defects in Lrp6 mutant mice. Dev Dyn (2010) 0.95
Xenopus frizzled-7 morphant displays defects in dorsoventral patterning and convergent extension movements during gastrulation. Genesis (2001) 0.95
Inversin, Wnt signaling and primary cilia. Differentiation (2011) 0.95
Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma. Hum Mol Genet (2012) 0.93
Generation of Lrp6 conditional gene-targeting mouse line for modeling and dissecting multiple birth defects/congenital anomalies. Dev Dyn (2010) 0.90
Association of Wnt3A gene variants with non-syndromic cleft lip with or without cleft palate in Chinese population. Arch Oral Biol (2010) 0.89
Zebrafish frizzled-2 morphant displays defects in body axis elongation. Genesis (2001) 0.87
Genetic interaction between Lrp6 and Wnt5a during mouse development. Dev Dyn (2010) 0.85
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TEAD mediates YAP-dependent gene induction and growth control. Genes Dev (2008) 9.88
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity (2008) 9.82
Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell (2004) 5.04
Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science (2003) 4.18
The vitelliform macular dystrophy protein defines a new family of chloride channels. Proc Natl Acad Sci U S A (2002) 3.73
Tissue/planar cell polarity in vertebrates: new insights and new questions. Development (2007) 3.66
Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7). Cell Metab (2005) 3.43
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J Neurosci (2006) 3.36
Telomere length is a determinant of emphysema susceptibility. Am J Respir Crit Care Med (2011) 3.28
A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse. J Neurosci (2003) 3.26
Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder. Nature (2011) 3.15
Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci U S A (2010) 2.66
Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell (2009) 2.63
Frizzled6 controls hair patterning in mice. Proc Natl Acad Sci U S A (2004) 2.54
Quantitative analysis of neuronal morphologies in the mouse retina visualized by using a genetically directed reporter. J Comp Neurol (2004) 2.47
Emergence of novel color vision in mice engineered to express a human cone photopigment. Science (2007) 2.41
Structure-function analysis of the bestrophin family of anion channels. J Biol Chem (2003) 2.30
The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes. J Neurosci (2005) 2.25
Frizzled-3 is required for the development of major fiber tracts in the rostral CNS. J Neurosci (2002) 2.23
Macular degeneration: recent advances and therapeutic opportunities. Nat Rev Neurosci (2006) 2.05
Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein. Cancer Res (2009) 2.05
Heavy metal contamination in western Xiamen Bay sediments and its vicinity, China. Mar Pollut Bull (2007) 2.02
An MRI-based atlas and database of the developing mouse brain. Neuroimage (2010) 1.99
Importance of group X-secreted phospholipase A2 in allergen-induced airway inflammation and remodeling in a mouse asthma model. J Exp Med (2007) 1.96
Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells. Neuron (2009) 1.95
The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia. J Neurosci (2005) 1.81
Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling. J Neurosci (2006) 1.64
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Loss of microRNA 122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G(1) -modulated P53 activity. Hepatology (2012) 1.61
Role of a locus control region in the mutually exclusive expression of human red and green cone pigment genes. Proc Natl Acad Sci U S A (2002) 1.59
Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity. Cell (2012) 1.54
High-level factor VIII gene expression in vivo achieved by nonviral liver-specific gene therapy vectors. Hum Gene Ther (2003) 1.49
Mutational analysis of Norrin-Frizzled4 recognition. J Biol Chem (2006) 1.48
The optokinetic reflex as a tool for quantitative analyses of nervous system function in mice: application to genetic and drug-induced variation. PLoS One (2008) 1.44
Cyclophilin A interacts with influenza A virus M1 protein and impairs the early stage of the viral replication. Cell Microbiol (2009) 1.40
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Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron (2011) 1.39
Resting mechanomyographic amplitude for the erector spinae and trapezius muscles following resistance exercise in a healthy population. Physiol Meas (2013) 1.38
The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease. Trends Mol Med (2010) 1.38
Order from disorder: Self-organization in mammalian hair patterning. Proc Natl Acad Sci U S A (2006) 1.37
Hepatitis B virus mRNA-mediated miR-122 inhibition upregulates PTTG1-binding protein, which promotes hepatocellular carcinoma tumor growth and cell invasion. J Virol (2012) 1.36
Tn7-based genome-wide random insertional mutagenesis of Candida glabrata. Genome Res (2003) 1.36
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Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision. Proc Natl Acad Sci U S A (2003) 1.30
New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling. PLoS One (2009) 1.28
Canonical WNT signaling components in vascular development and barrier formation. J Clin Invest (2014) 1.27
Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis. Dev Cell (2007) 1.27
Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes. Development (2010) 1.26
Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene. Pharmacogenet Genomics (2008) 1.22
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Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammation. J Exp Med (2008) 1.18
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An essential role for frizzled 5 in mammalian ocular development. Development (2008) 1.11
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The genomic response of the retinal pigment epithelium to light damage and retinal detachment. J Neurosci (2008) 1.09
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Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1. J Virol (2010) 1.08
Pluripotin combined with leukemia inhibitory factor greatly promotes the derivation of embryonic stem cell lines from refractory strains. Stem Cells (2009) 1.08
An essential role for Frizzled5 in neuronal survival in the parafascicular nucleus of the thalamus. J Neurosci (2008) 1.07
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Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse. Invest Ophthalmol Vis Sci (2007) 1.07
When whorls collide: the development of hair patterns in frizzled 6 mutant mice. Development (2010) 1.06
Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis. J Neurosci (2012) 1.05
Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling. Elife (2012) 1.05
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cDNA-AFLP analysis reveals the adaptive responses of citrus to long-term boron-toxicity. BMC Plant Biol (2014) 1.03
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3. Diabetes (2012) 1.01
The gastrointestinal manifestations of telomere-mediated disease. Aging Cell (2013) 1.00
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Heat shock protein 70 inhibits the activity of Influenza A virus ribonucleoprotein and blocks the replication of virus in vitro and in vivo. PLoS One (2011) 0.98
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A strabismus susceptibility locus on chromosome 7p. Proc Natl Acad Sci U S A (2003) 0.97
Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17. J Biol Chem (2009) 0.97
Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney. Development (2011) 0.96
Proximal and distal sequences control UV cone pigment gene expression in transgenic zebrafish. J Biol Chem (2004) 0.96
Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons. Elife (2013) 0.96
Human platelet lysate supports ex vivo expansion and enhances osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. Cell Biol Int (2011) 0.95
Healthcare resource use and costs associated with cervical, vaginal and vulvar cancers in a large U.S. health plan. Gynecol Oncol (2008) 0.95
Ndfip1 negatively regulates RIG-I-dependent immune signaling by enhancing E3 ligase Smurf1-mediated MAVS degradation. J Immunol (2012) 0.95
Cyclin T1/CDK9 interacts with influenza A virus polymerase and facilitates its association with cellular RNA polymerase II. J Virol (2010) 0.94
EGFR mutation status and its impact on survival of Chinese non-small cell lung cancer patients with brain metastases. Tumour Biol (2013) 0.94
Responses of hair follicle-associated structures to loss of planar cell polarity signaling. Proc Natl Acad Sci U S A (2013) 0.93
Receptor for retrograde transport in the apicomplexan parasite Toxoplasma gondii. Eukaryot Cell (2005) 0.93
Influenza A virus M1 blocks the classical complement pathway through interacting with C1qA. J Gen Virol (2009) 0.93
Increased prevalence of hepatitis C virus subtype 6a in China: a comparison between 2004-2007 and 2008-2011. Arch Virol (2014) 0.92
Preferential sites for the integration and disruption of human papillomavirus 16 in cervical lesions. J Clin Virol (2013) 0.92
Role of an alternatively spliced form of alphaII-spectrin in localization of connexin 43 in cardiomyocytes and regulation by stress-activated protein kinase. J Mol Cell Cardiol (2007) 0.92
Hepatitis B virus inhibits apoptosis of hepatoma cells by sponging the MicroRNA 15a/16 cluster. J Virol (2013) 0.92
Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis. Proc Natl Acad Sci U S A (2013) 0.91