Published in Development on December 01, 2012
ROS, Notch, and Wnt signaling pathways: crosstalk between three major regulators of cardiovascular biology. Biomed Res Int (2014) 0.84
The genetics of colony form and function in Caribbean Acropora corals. BMC Genomics (2014) 0.84
Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling. PLoS One (2013) 0.83
The Dishevelled Protein Family: Still Rather a Mystery After Over 20 Years of Molecular Studies. Curr Top Dev Biol (2016) 0.79
Negative control of CSL gene transcription by stress/DNA damage response and p53. Cell Cycle (2016) 0.79
Notch: A multi-functional integrating system of microenvironmental signals. Dev Biol (2016) 0.78
Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia. Cancer Cell (2016) 0.77
XTalkDB: a database of signaling pathway crosstalk. Nucleic Acids Res (2016) 0.75
Notch Signaling in Pancreatic Development. Int J Mol Sci (2015) 0.75
The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt. PLoS Comput Biol (2017) 0.75
Dishevelled Paralogs in Vertebrate Development: Redundant or Distinct? Front Cell Dev Biol (2017) 0.75
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res (1989) 22.73
Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell (2009) 18.31
Notch signalling: a simple pathway becomes complex. Nat Rev Mol Cell Biol (2006) 13.12
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature (2005) 11.49
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer. Nat Chem Biol (2009) 9.43
Notch signals control the fate of immature progenitor cells in the intestine. Nature (2005) 6.13
Notch signaling regulates mammary stem cell function and luminal cell-fate commitment. Cell Stem Cell (2008) 4.45
Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol (2005) 4.34
Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture. Cell Stem Cell (2010) 4.25
A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell (2008) 3.94
Aberrant activation of notch signaling in human breast cancer. Cancer Res (2006) 3.92
Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol Cell (2004) 3.85
Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev (2001) 3.52
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development (2005) 3.51
Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell (2009) 3.50
Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives. Development (1997) 3.42
The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate. Development (1997) 2.79
The evolution of signalling pathways in animal development. Nat Rev Genet (2003) 2.79
Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev (2002) 2.64
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proc Natl Acad Sci U S A (2009) 2.63
Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Curr Biol (2000) 2.58
Dishevelled promotes axon differentiation by regulating atypical protein kinase C. Nat Cell Biol (2007) 2.55
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism. Proc Natl Acad Sci U S A (2006) 2.49
Direct regulation of intestinal fate by Notch. Proc Natl Acad Sci U S A (2005) 2.41
Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science (1996) 2.31
The Xenopus homolog of Drosophila Suppressor of Hairless mediates Notch signaling during primary neurogenesis. Development (1997) 2.30
Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation. Development (2003) 2.21
Crossing paths with Notch in the hyper-network. Curr Opin Cell Biol (2007) 2.20
Wnt/Notch signalling and information processing during development. Development (2008) 2.18
Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye. Curr Biol (2002) 2.10
Nuclear localization is required for Dishevelled function in Wnt/beta-catenin signaling. J Biol (2005) 2.06
Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways. J Biol Chem (2003) 2.04
Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development (1996) 2.03
Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. Dev Cell (2007) 1.99
Wnt proteins in mammary development and cancer. J Mammary Gland Biol Neoplasia (2004) 1.98
An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway. Proc Natl Acad Sci U S A (2011) 1.92
Notch4 and Wnt-1 proteins function to regulate branching morphogenesis of mammary epithelial cells in an opposing fashion. Dev Biol (1998) 1.90
beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion. Development (1999) 1.89
Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction. J Cell Biol (2008) 1.89
A two-step mechanism generates the spacing pattern of the ciliated cells in the skin of Xenopus embryos. Development (1999) 1.75
Glycogen synthase kinase-3beta modulates notch signaling and stability. Curr Biol (2002) 1.66
Neural crest regulates myogenesis through the transient activation of NOTCH. Nature (2011) 1.55
Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate. Curr Biol (2001) 1.55
Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3. Cell Signal (2007) 1.55
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members. Proc Natl Acad Sci U S A (2001) 1.54
Identification of the Axin and Frat binding region of glycogen synthase kinase-3. J Biol Chem (2001) 1.49
Truncated mutants of the putative Wnt receptor LRP6/Arrow can stabilize beta-catenin independently of Frizzled proteins. Oncogene (2004) 1.47
Dissecting the mechanisms of suppressor of hairless function. Dev Biol (2000) 1.32
Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain. Development (2005) 1.25
wingless refines its own expression domain on the Drosophila wing margin. Nature (1996) 1.24
Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling. Oncogene (2005) 1.21
Notch activation regulates the segregation and differentiation of rhombomere boundary cells in the zebrafish hindbrain. Dev Cell (2004) 1.20
Intrinsic differences between the superficial and deep layers of the Xenopus ectoderm control primary neuronal differentiation. Dev Cell (2002) 1.08
Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers. Oncogene (2002) 1.08
Different spatial and temporal interactions between Notch, wingless, and vestigial specify proximal and distal pattern elements of the wing in Drosophila. Dev Biol (1998) 1.07
Dorsoventral lineage restriction in wing imaginal discs requires Notch. Nature (1999) 1.07
PAR1 specifies ciliated cells in vertebrate ectoderm downstream of aPKC. Development (2007) 0.99
Mutational analysis of the J recombination signal sequence binding protein (RBP-J)/Epstein-Barr virus nuclear antigen 2 (EBNA2) and RBP-J/Notch interaction. Eur J Biochem (2001) 0.95
Expression of Notch receptors, ligands, and target genes during development of the mouse mammary gland. J Cell Physiol (2011) 0.90
Numb regulates Notch1, but not Notch3, during myogenesis. Mech Dev (2011) 0.90
Wingless modulates the effects of dominant negative notch molecules in the developing wing of Drosophila. Dev Biol (1999) 0.88
Planar cell polarity controls directional Notch signaling in the Drosophila leg. Development (2012) 0.83
Wingless modulates the ligand independent traffic of Notch through Dishevelled. Fly (Austin) (2010) 0.82
Aberrant activation of notch signaling in human breast cancer. Cancer Res (2006) 3.92
A myristoyl/phosphotyrosine switch regulates c-Abl. Cell (2003) 3.48
Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proc Natl Acad Sci U S A (2010) 3.03
Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J Natl Cancer Inst (2007) 2.75
Multiple reaction monitoring to identify sites of protein phosphorylation with high sensitivity. Mol Cell Proteomics (2005) 2.26
Evaluation of the current knowledge limitations in breast cancer research: a gap analysis. Breast Cancer Res (2008) 2.06
Autoinhibition of c-Abl. Cell (2002) 1.93
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer. Breast Cancer Res (2013) 1.92
Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration. Nat Cell Biol (2013) 1.72
CSL-independent Notch signalling: a checkpoint in cell fate decisions during development? Curr Opin Genet Dev (2002) 1.68
Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity. Development (2005) 1.62
Bax exists in a dynamic equilibrium between the cytosol and mitochondria to control apoptotic priming. Mol Cell (2013) 1.60
Maintenance of embryonic auxin distribution for apical-basal patterning by PIN-FORMED-dependent auxin transport in Arabidopsis. Plant Cell (2005) 1.60
c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis. EMBO J (2002) 1.41
Notch activation induces Akt signaling via an autocrine loop to prevent apoptosis in breast epithelial cells. Cancer Res (2009) 1.40
Desmosomal cadherin misexpression alters beta-catenin stability and epidermal differentiation. Mol Cell Biol (2005) 1.21
Caspase-dependent cleavage of c-Abl contributes to apoptosis. Mol Cell Biol (2003) 1.20
Wnt/beta-catenin signaling stimulates chondrogenic and inhibits adipogenic differentiation of pericytes: potential relevance to vascular disease? Circ Res (2007) 1.19
Rapid cleavage of RNA by RNase E in the absence of 5' monophosphate stimulation. Mol Microbiol (2009) 1.14
Targeting inhibitor of apoptosis proteins in combination with ErbB antagonists in breast cancer. Breast Cancer Res (2009) 1.10
Wnt-Notch signalling crosstalk in development and disease. Cell Mol Life Sci (2014) 1.10
Aurora A kinase regulates mammary epithelial cell fate by determining mitotic spindle orientation in a Notch-dependent manner. Cell Rep (2013) 1.07
Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells. Cancer Res (2007) 1.07
Enhanced Edar signalling has pleiotropic effects on craniofacial and cutaneous glands. PLoS One (2009) 1.02
Cysteine protease gene expression and proteolytic activity during senescence of Alstroemeria petals. J Exp Bot (2002) 1.01
pTransgenesis: a cross-species, modular transgenesis resource. Development (2011) 0.99
Cooperation between Wnt and Notch signalling in human breast cancer. Breast Cancer Res (2007) 0.96
Specific β-containing integrins exert differential control on proliferation and two-dimensional collective cell migration in mammary epithelial cells. J Biol Chem (2012) 0.95
Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo. Development (2010) 0.94
How adhesion signals reach a mitochondrial conclusion--ECM regulation of apoptosis. Curr Opin Cell Biol (2009) 0.93
Temporal and spatial expression of FGF ligands and receptors during Xenopus development. Dev Dyn (2009) 0.92
Role of early plasma membrane events in chemotherapy-induced cell death. Drug Resist Updat (2005) 0.90
BDNF promotes target innervation of Xenopus mandibular trigeminal axons in vivo. BMC Dev Biol (2007) 0.89
Metabolic control of transcription: paradigms and lessons from Saccharomyces cerevisiae. Biochem J (2008) 0.88
Spatially restricted translation of the xCR1 mRNA in Xenopus embryos. Mol Cell Biol (2009) 0.87
No association between cigarette smoking and incidence of plasma cell myeloma: a meta-analysis of 17 observational studies. Am J Hematol (2012) 0.86
Density of human bone marrow stromal cells regulates commitment to vascular lineages. Stem Cell Res (2011) 0.85
Notch receptor encodes two structurally separable functions in Drosophila: a genetic analysis. Dev Dyn (2006) 0.85
A functional genome-wide in vivo screen identifies new regulators of signalling pathways during early Xenopus embryogenesis. PLoS One (2013) 0.79
Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin. Cytoskeleton (Hoboken) (2014) 0.79
Experimental generation of carcinoma-associated fibroblasts (CAFs) from human mammary fibroblasts. J Vis Exp (2011) 0.79
Is there more to Wnt signalling in breast cancer than stabilisation of beta-catenin? Breast Cancer Res (2009) 0.77
Activin ligands are required for the re-activation of Smad2 signalling after neurulation and vascular development in Xenopus tropicalis. Int J Dev Biol (2014) 0.75