Published in Arthritis on October 24, 2012
Regulatory T cell subsets in filarial infection and their function. Front Immunol (2013) 0.90
Inflammation and hypertension: new understandings and potential therapeutic targets. Curr Hypertens Rep (2015) 0.89
A Promoter Region Polymorphism in PDCD-1 Gene Is Associated with Risk of Rheumatoid Arthritis in the Han Chinese Population of Southeastern China. Int J Genomics (2014) 0.80
Ubiquitin-dependent regulation of Foxp3 and Treg function. Immunol Rev (2015) 0.78
Increased circulating Th17 cell populations and elevated CSF osteopontin and IL-17 concentrations in patients with Guillain-Barré syndrome. J Clin Immunol (2013) 0.78
Relationships between IL-17(+) subsets, Tregs and pDCs that distinguish among SIV infected elite controllers, low, medium and high viral load rhesus macaques. PLoS One (2013) 0.78
Functional improvement of regulatory T cells from rheumatoid arthritis subjects induced by capsular polysaccharide glucuronoxylomannogalactan. PLoS One (2014) 0.75
Control of regulatory T cell development by the transcription factor Foxp3. Science (2003) 40.32
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol (2003) 38.57
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol (1995) 29.42
Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol (2001) 25.63
An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol (2003) 19.16
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med (1998) 19.03
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature (1997) 16.28
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med (2006) 14.33
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med (2000) 13.13
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol (2005) 13.03
CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol (2002) 12.73
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol (2001) 12.00
How regulatory T cells work. Nat Rev Immunol (2008) 11.66
A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol (2005) 11.48
Foxp3-dependent programme of regulatory T-cell differentiation. Nature (2007) 9.48
FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell (2006) 9.24
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta. J Exp Med (2001) 8.69
Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science (1994) 8.69
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med (1996) 8.54
NKT cells: what's in a name? Nat Rev Immunol (2004) 7.84
Origin of regulatory T cells with known specificity for antigen. Nat Immunol (2002) 7.49
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity (2000) 6.97
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature (2010) 6.87
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med (2005) 6.87
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol Rev (2006) 6.08
Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology (1970) 6.06
Interleukin-10 and related cytokines and receptors. Annu Rev Immunol (2004) 5.41
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity (2002) 5.38
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med (2002) 5.28
Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo. J Exp Med (2003) 5.23
A thymic precursor to the NK T cell lineage. Science (2002) 4.66
TNF downmodulates the function of human CD4+CD25hi T-regulatory cells. Blood (2006) 4.63
Regulatory T cells and infection: a dangerous necessity. Nat Rev Immunol (2007) 4.56
Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J Exp Med (2003) 4.41
NKT cells: facts, functions and fallacies. Immunol Today (2000) 4.40
In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J Exp Med (2000) 4.37
Developmental regulation of Foxp3 expression during ontogeny. J Exp Med (2005) 4.32
A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family. Nature (1987) 3.96
Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4. Nat Immunol (2002) 3.91
Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans. Hum Immunol (2005) 3.65
Regulatory T cells: friend or foe in immunity to infection? Nat Rev Immunol (2004) 3.61
Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes. J Exp Med (1995) 3.58
Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nat Rev Immunol (2005) 3.48
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol (2004) 3.46
NKT cells derive from double-positive thymocytes that are positively selected by CD1d. Nat Immunol (2001) 3.37
Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected]. J Exp Med (2002) 3.31
Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells. Immunol Rev (2001) 3.31
Protein kinase C-theta mediates negative feedback on regulatory T cell function. Science (2010) 3.31
Foxp3 and natural regulatory T cells: key to a cell lineage? Immunity (2003) 3.29
Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity (2003) 3.28
A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage. J Exp Med (2002) 3.13
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells. J Immunol (2001) 3.13
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function. Eur J Immunol (2004) 3.08
Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J Exp Med (2002) 3.02
Control points in NKT-cell development. Nat Rev Immunol (2007) 2.92
Cutting edge: NKT cells constitutively express IL-23 receptor and RORgammat and rapidly produce IL-17 upon receptor ligation in an IL-6-independent fashion. J Immunol (2008) 2.90
Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature (2003) 2.83
Proinflammatory mediator-induced reversal of CD4+,CD25+ regulatory T cell-mediated suppression in rheumatoid arthritis. Arthritis Rheum (2007) 2.81
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells. Blood (2004) 2.76
Regulatory T cells protect from local and systemic bone destruction in arthritis. J Immunol (2010) 2.70
High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J Exp Med (1994) 2.70
Regulation of immunity by self-reactive T cells. Nature (2005) 2.63
The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion. Proc Natl Acad Sci U S A (2003) 2.62
Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. Immunity (2009) 2.35
Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-beta1-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients. J Clin Invest (1996) 2.27
NKT cells: T lymphocytes with innate effector functions. Curr Opin Immunol (2007) 2.19
Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period. J Exp Med (2005) 2.12
Tr1 cells: from discovery to their clinical application. Semin Immunol (2006) 2.05
Rapid death and regeneration of NKT cells in anti-CD3epsilon- or IL-12-treated mice: a major role for bone marrow in NKT cell homeostasis. Immunity (1998) 2.03
Signaling lymphocytic activation molecule-associated protein controls NKT cell functions. J Immunol (2005) 1.98
CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer. Clin Cancer Res (2007) 1.94
The regulatory T cell family: distinct subsets and their interrelations. J Immunol (2003) 1.92
Foxp3+ CD25- CD4 T cells constitute a reservoir of committed regulatory cells that regain CD25 expression upon homeostatic expansion. Proc Natl Acad Sci U S A (2005) 1.90
Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis. Ann Rheum Dis (2010) 1.86
The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol (2002) 1.84
Granulocyte-macrophage colony-stimulating factor regulates effector differentiation of invariant natural killer T cells during thymic ontogeny. Immunity (2006) 1.82
T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells. Blood (2005) 1.80
Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes. Blood (2003) 1.79
Early events in the thymus affect the balance of effector and regulatory T cells. Nature (2006) 1.78
Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines. Eur J Immunol (2002) 1.76
The ETS protein MEF plays a critical role in perforin gene expression and the development of natural killer and NK-T cells. Immunity (2002) 1.70
Defects in CTLA-4 are associated with abnormal regulatory T cell function in rheumatoid arthritis. Proc Natl Acad Sci U S A (2008) 1.69
NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation. J Immunol (2002) 1.67
CD4+CD25+ Tregs and NKT cells: regulators regulating regulators. Trends Immunol (2006) 1.66
Revival of CD8+ Treg-mediated suppression. Trends Immunol (2008) 1.63
CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells. J Exp Med (2003) 1.63
STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells. Int Immunol (2008) 1.58
Developmental program of mouse Valpha14i NKT cells. Curr Opin Immunol (2005) 1.58
GATA-3 regulates the development and function of invariant NKT cells. J Immunol (2006) 1.57
Regulatory T cells: development, function and role in autoimmunity. Autoimmun Rev (2005) 1.57
Chemokine receptor expression and function in CD4+ T lymphocytes with regulatory activity. J Immunol (2001) 1.55
Functionally distinct NKT cell subsets and subtypes. J Exp Med (2005) 1.54
Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritis. Rheumatology (Oxford) (2009) 1.51
TGF-beta and regulatory T cell in immunity and autoimmunity. J Clin Immunol (2008) 1.49
Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation. Blood (2004) 1.48
Is FOXP3 a bona fide marker for human regulatory T cells? Eur J Immunol (2008) 1.47
Peptide-specific CD8 T regulatory cells use IFN-gamma to elaborate TGF-beta-based suppression. J Immunol (2005) 1.38
Lack of suppressor cell activity in rheumatoid synovial lymphocytes. Scand J Immunol (1979) 1.36
How many mechanisms do regulatory T cells need? Eur J Immunol (2008) 1.34
Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis. J Dermatolog Treat (2010) 1.66
Histamine and histamine receptors in pathogenesis and treatment of multiple sclerosis. Neuropharmacology (2010) 1.07
Th17 Cells in Immunopathogenesis and treatment of rheumatoid arthritis. Int J Rheum Dis (2013) 0.89
The potential role of angiogenic factors in rheumatoid arthritis. Int J Rheum Dis (2014) 0.89
Artemether: a new therapeutic strategy in experimental rheumatoid arthritis. Immunopharmacol Immunotoxicol (2005) 0.87
The potential role of proinflammatory and antiinflammatory cytokines in Alzheimer disease pathogenesis. Immunopharmacol Immunotoxicol (2012) 0.86
Regulatory T-cell as orchestra leader in immunosuppression process of multiple sclerosis. Immunopharmacol Immunotoxicol (2011) 0.85
Prostaglandins and rheumatoid arthritis. Arthritis (2012) 0.85
Imatinib mesylate: an innovation in treatment of autoimmune diseases. Recent Pat Inflamm Allergy Drug Discov (2013) 0.84
Soy protein and genistein improves renal antioxidant status in experimental nephrotic syndrome. Nefrologia (2014) 0.84
Natural killer cells and their role in rheumatoid arthritis: friend or foe? ScientificWorldJournal (2012) 0.84
The immunopathogenic role of reactive oxygen species in Alzheimer disease. Iran J Allergy Asthma Immunol (2012) 0.83
Intermittent feeding attenuates clinical course of experimental autoimmune encephalomyelitis in C57BL/6 mice. Avicenna J Med Biotechnol (2010) 0.83
New therapeutic approach by G2013 in experimental model of multiple sclerosis. Acta Neurol Belg (2014) 0.82
Immune reactivity of Brucella melitensis-vaccinated rabbit serum with recombinant Omp31 and DnaK proteins. Iran J Microbiol (2013) 0.82
Bee venom, immunostimulant or immunosuppressor? Insight into the effect on matrix metalloproteinases and interferons. Immunopharmacol Immunotoxicol (2005) 0.81
The role of natural killer T cells in B cell malignancies. Tumour Biol (2013) 0.81
The deviated balance between regulatory T cell and Th17 in autoimmunity. Immunopharmacol Immunotoxicol (2012) 0.81
Treatment of experimental nephrotic syndrome with artesunate. Int J Toxicol (2007) 0.81
Anti-citrullinated protein antibodies and their clinical utility in rheumatoid arthritis. Int J Rheum Dis (2013) 0.81
Siglec-8 and Siglec-F, the new therapeutic targets in asthma. Immunopharmacol Immunotoxicol (2012) 0.80
The effect of dietary oils on cecal microflora in experimental colitis in mice. Indian J Gastroenterol (2008) 0.80
Evaluation of CD4+CD25+FOXP3+ regulatory T cells function in patients with common variable immunodeficiency. Cell Immunol (2013) 0.79
Alteration in frequency and function of CD4⁺CD25⁺FOXP3⁺ regulatory T cells in patients with immune thrombocytopenic purpura. Iran J Allergy Asthma Immunol (2014) 0.79
The skewed balance between Tregs and Th17 in chronic lymphocytic leukemia. Future Oncol (2015) 0.79
Properties of immature myeloid progenitors with nitric-oxide-dependent immunosuppressive activity isolated from bone marrow of tumor-free mice. PLoS One (2013) 0.79
Detection of the intercellular adhesion gene cluster (ica) in clinical Staphylococcus aureus isolates. GMS Hyg Infect Control (2013) 0.79
The neglected role of histamine in Alzheimer's disease. Am J Alzheimers Dis Other Demen (2013) 0.79
Therapeutic effects of dasatinib in mouse model of multiple sclerosis. Immunopharmacol Immunotoxicol (2015) 0.78
Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy. Tumour Biol (2015) 0.78
Chemoprevention by pyrimethamine. Immunopharmacol Immunotoxicol (2005) 0.78
Influenza Virus-like Particle Containing Two Different Subtypes of Hemagglutinin Confers Protection in Mice Against Lethal Challenge With A/PR8 (H1N1) and A/HK (H3N2) Viruses. Iran Red Crescent Med J (2013) 0.78
In vitro sensitivity of leukemia cells to propranolol. J Clin Med Res (2009) 0.78
Immunopharmacological role of the leukotriene receptor antagonists and inhibitors of leukotrienes generating enzymes in multiple sclerosis. Immunopharmacol Immunotoxicol (2010) 0.77
Prostaglandins in pathogenesis and treatment of multiple sclerosis. Immunopharmacol Immunotoxicol (2010) 0.77
Effect of pyrimethamine in experimental rheumatoid arthritis. Med Sci Monit (2005) 0.77
Does lipoic acid consumption affect the cytokine profile in multiple sclerosis patients: a double-blind, placebo-controlled, randomized clinical trial. Neuroimmunomodulation (2014) 0.77
Regulatory T cells as a therapeutic tool to induce solid-organ transplant tolerance: current clinical experiences. Exp Clin Transplant (2013) 0.77
All-trans-retinoic Acid differentially regulates proliferation of normal and leukemic B cells from different subsets of chronic lymphocytic leukemia. Nutr Cancer (2015) 0.77
The potential role of iNKT cells in experimental allergic encephalitis and multiple sclerosis. Immunopharmacol Immunotoxicol (2014) 0.76
Novel therapeutic approach by nicotine in experimental model of multiple sclerosis. Innov Clin Neurosci (2013) 0.76
The role of leukotrienes in immunopathogenesis of rheumatoid arthritis. Mod Rheumatol (2013) 0.76
Increased production of nitric oxide by neutrophils from patients with chronic granulomatous disease on interferon-gamma treatment. Int Immunopharmacol (2012) 0.76
Differential regulation of B-cell proliferation by IL21 in different subsets of chronic lymphocytic leukemia. Cytokine (2013) 0.76
Polyunsaturated fatty acids, microflora and colitis. Ann Nutr Metab (2009) 0.76
Apoptotic efficacy and inhibitory effect of dexamethasone on matrix metalloproteinase. Med Sci Monit (2005) 0.76
Mesenchymal Stem Cells in the Treatment of Amyotrophic Lateral Sclerosis. Curr Stem Cell Res Ther (2016) 0.75
Therapeutic effect of EDTA in experimental model of multiple sclerosis. Immunopharmacol Immunotoxicol (2010) 0.75
IL-22 Produced by T helper Cell 22 as a New player in the Pathogenesis of Immune Thrombocytopenia. Endocr Metab Immune Disord Drug Targets (2015) 0.75
Positive and negative effects of prostaglandins in Alzheimer's disease. Psychiatry Clin Neurosci (2013) 0.75
The role of leukotrienes in immunopathogenesis of rheumatoid arthritis. Mod Rheumatol (2014) 0.75
Effect of lipoic acid consumption on oxidative stress among multiple sclerosis patients: a randomized controlled clinical trial. Nutr Neurosci (2013) 0.75
In vitro assessment of bee venom effects on matrix metalloproteinase activity and interferon production. Iran J Allergy Asthma Immunol (2005) 0.75
Anti-aging effects of M2000 (β-D-mannuronic acid) as a novel immunosuppressive drug on the enzymatic and non-enzymatic oxidative stress parameters in an experimental model. J Basic Clin Physiol Pharmacol (2017) 0.75
Primary ciliary dyskinesia in six patients with bronchiectasis. Pneumonol Alergol Pol (2016) 0.75
Conversion of calcineurin inhibitors with mammalian target of rapamycin inhibitors after kidney transplant. Exp Clin Transplant (2013) 0.75
Multiple Low Doses of 5-Fluorouracil Diminishes Immunosuppression by Myeloid Derived Suppressor Cells in Murine Melanoma Model. Iran J Immunol (2015) 0.75
Autoimmunity in Primary Antibody Deficiencies. Int Arch Allergy Immunol (2016) 0.75
Anti-aging property of G2013 molecule as a novel immunosuppressive agent on enzymatic and non-enzymatic oxidative stress determinants in Rat model. Curr Drug Discov Technol (2016) 0.75
Immunology of Chronic Obstructive Pulmonary Disease and Sulfur Mustard Induced Airway Injuries: Implications for Immunotherapeutic Interventions. Curr Pharm Des (2016) 0.75
Therapeutic approach to multiple sclerosis by novel oral drug. Recent Pat Inflamm Allergy Drug Discov (2011) 0.75