Published in Ther Adv Endocrinol Metab on August 01, 2010
The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer. Metabolism (2012) 1.31
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Brain delivery of proteins via their fatty acid and block copolymer modifications. J Drug Target (2013) 0.77
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Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism. Cell (2008) 7.37
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature (2003) 6.87
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med (2004) 6.16
Inhibition of food intake in obese subjects by peptide YY3-36. N Engl J Med (2003) 5.83
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem (2002) 5.53
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem (2002) 4.11
Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes (2009) 3.17
A role for intestinal endocrine cell-expressed g protein-coupled receptor 119 in glycemic control by enhancing glucagon-like Peptide-1 and glucose-dependent insulinotropic Peptide release. Endocrinology (2008) 3.04
Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents. Cell Metab (2006) 2.80
The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse. Cell Metab (2005) 2.71
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Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules. Br J Pharmacol (2006) 2.62
Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43. Endocrinology (2005) 2.32
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci U S A (2004) 2.08
A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs. Biochem Biophys Res Commun (2003) 2.03
Gut microbiota fermentation of prebiotics increases satietogenic and incretin gut peptide production with consequences for appetite sensation and glucose response after a meal. Am J Clin Nutr (2009) 2.00
Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology (2008) 1.97
Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells. Diabetologia (2008) 1.97
A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release. Endocrinology (2007) 1.91
Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. J Biol Chem (2009) 1.91
Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res (2006) 1.90
International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions. Pharmacol Rev (2008) 1.80
Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Mol Pharmacol (2008) 1.75
GPR119 is essential for oleoylethanolamide-induced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell. Diabetes (2009) 1.69
The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding. Diabetes (2008) 1.66
Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice. Diabetes (2009) 1.64
Absence of the G protein-coupled receptor G2A in mice promotes monocyte/endothelial interactions in aorta. Circ Res (2007) 1.60
The regulation of adipogenesis through GPR120. Biochem Biophys Res Commun (2007) 1.55
ApoE-dependent modulation of HDL and atherosclerosis by G2A in LDL receptor-deficient mice independent of bone marrow-derived cells. Arterioscler Thromb Vasc Biol (2009) 1.55
Free fatty acids induce cholecystokinin secretion through GPR120. Naunyn Schmiedebergs Arch Pharmacol (2007) 1.52
GPR119 agonists: a promising new approach for the treatment of type 2 diabetes and related metabolic disorders. Curr Opin Drug Discov Devel (2009) 1.48
Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis. Prostaglandins Other Lipid Mediat (2009) 1.45
The year in G protein-coupled receptor research. Mol Endocrinol (2009) 1.44
Gut microbiota as a regulator of energy homeostasis and ectopic fat deposition: mechanisms and implications for metabolic disorders. Curr Opin Lipidol (2010) 1.42
Short-chain fatty acids modify colonic motility through nerves and polypeptide YY release in the rat. Am J Physiol (1998) 1.39
The fermentable fibre inulin increases postprandial serum short-chain fatty acids and reduces free-fatty acids and ghrelin in healthy subjects. Appl Physiol Nutr Metab (2010) 1.39
Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch Pharmacol (2009) 1.38
GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity. Br J Pharmacol (2007) 1.33
Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A. Blood (2004) 1.31
Adaptation of colonic fermentation and glucagon-like peptide-1 secretion with increased wheat fibre intake for 1 year in hyperinsulinaemic human subjects. Br J Nutr (2009) 1.28
Concentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial. Nutr J (2007) 1.27
Discovery of potent and selective agonists for the free fatty acid receptor 1 (FFA(1)/GPR40), a potential target for the treatment of type II diabetes. J Med Chem (2008) 1.25
The G-protein-coupled receptor 40 family (GPR40-GPR43) and its role in nutrient sensing. Biochem Soc Trans (2006) 1.25
Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1. J Biol Chem (2005) 1.22
Progress in the discovery and development of small-molecule modulators of G-protein-coupled receptor 40 (GPR40/FFA1/FFAR1): an emerging target for type 2 diabetes. Expert Opin Ther Pat (2009) 1.20
Molecular pharmacology of promiscuous seven transmembrane receptors sensing organic nutrients. Mol Pharmacol (2009) 1.20
Alcohol consumption and risk of cardiovascular disease and death in women: potential mediating mechanisms. Circulation (2009) 1.18
GPR expression in the rat taste bud relating to fatty acid sensing. Biomed Res (2007) 1.18
GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis. J Endocrinol (2009) 1.17
GPR119 agonists for the treatment of type 2 diabetes. Expert Opin Ther Pat (2009) 1.17
Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119. J Med Chem (2008) 1.16
Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A. J Biol Chem (2005) 1.15
GPR40 is expressed in glucagon producing cells and affects glucagon secretion. Biochem Biophys Res Commun (2007) 1.13
Colocalization of GPR120 with phospholipase-Cbeta2 and alpha-gustducin in the taste bud cells in mice. Neurosci Lett (2008) 1.12
Cloning and characterization of the rat free fatty acid receptor GPR120: in vivo effect of the natural ligand on GLP-1 secretion and proliferation of pancreatic beta cells. Naunyn Schmiedebergs Arch Pharmacol (2008) 1.10
G2A as a receptor for oxidized free fatty acids. Prostaglandins Other Lipid Mediat (2008) 1.10
Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their effects on insulin secretion in MIN6c4 insulinoma cells. Br J Pharmacol (2008) 1.09
Two arginine-glutamate ionic locks near the extracellular surface of FFAR1 gate receptor activation. J Biol Chem (2008) 1.09
Identification of G protein-coupled receptor 120-selective agonists derived from PPARgamma agonists. J Med Chem (2008) 1.08
G-protein coupled receptors mediating long chain fatty acid signalling in the pancreatic beta-cell. Biochem Pharmacol (2009) 1.04
Loss of G2A promotes macrophage accumulation in atherosclerotic lesions of low density lipoprotein receptor-deficient mice. J Lipid Res (2005) 1.04
Expression of free fatty acid receptor GPR40 in the neurogenic niche of adult monkey hippocampus. Hippocampus (2008) 1.02
G2A plays proinflammatory roles in human keratinocytes under oxidative stress as a receptor for 9-hydroxyoctadecadienoic acid. J Invest Dermatol (2007) 1.01
N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119. Mol Endocrinol (2009) 1.01
The long-chain fatty acid receptor, GPR40, and glucolipotoxicity: investigations using GPR40-knockout mice. Biochem Soc Trans (2008) 0.99
Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion. J Control Release (2008) 0.98
Cloning, expression, and pharmacological characterization of the GPR120 free fatty acid receptor from cynomolgus monkey: comparison with human GPR120 splice variants. Comp Biochem Physiol B Biochem Mol Biol (2009) 0.95
Factors related to colonic fermentation of nondigestible carbohydrates of a previous evening meal increase tissue glucose uptake and moderate glucose-associated inflammation. Am J Clin Nutr (2009) 0.91
Expression of G2A, a receptor for lysophosphatidylcholine, by macrophages in murine, rabbit, and human atherosclerotic plaques. Arterioscler Thromb Vasc Biol (2002) 0.89
G2A deficiency in mice promotes macrophage activation and atherosclerosis. Circ Res (2008) 0.89
Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists. Bioorg Med Chem Lett (2008) 0.88
Regulation of adipocyte differentiation by histone deacetylase inhibitors. Arch Pharm Res (2009) 0.84
Caprylic acid infusion acts in the liver to decrease food intake in rats. Physiol Behav (2005) 0.82
The G protein-coupled receptor G2A: involvement in hepatic lipid metabolism and gallstone formation in mice. Hepatology (2008) 0.82
Effects of sodium butyrate on the differentiation of pancreatic and hepatic progenitor cells from mouse embryonic stem cells. J Cell Biochem (2010) 0.81
Combination of GLP-1 and sodium butyrate promote differentiation of pancreatic progenitor cells into insulin-producing cells. Tissue Cell (2008) 0.81
Decrease of food intake in rats after ingestion of medium-chain triacylglycerol. J Nutr Sci Vitaminol (Tokyo) (2009) 0.79
Parenteral medium-chain triglyceride-induced neutrophil activation is not mediated by a Pertussis Toxin sensitive receptor. Clin Nutr (2008) 0.78
Moderate alcohol intake is associated with decreased risk of insulin resistance among individuals with vitamin D insufficiency. Nutrition (2010) 0.77
Mechanism of ethanol-induced insulin secretion from INS-1 and INS-1E tumor cell lines. Cell Physiol Biochem (2009) 0.76
Neuroimmunological effects of physical exercise in depression. Brain Behav Immun (2011) 1.54
5-HTTLPR biases amygdala activity in response to masked facial expressions in major depression. Neuropsychopharmacology (2007) 1.44
Clinical risk factors for weight gain during psychopharmacologic treatment of depression: results from 2 large German observational studies. J Clin Psychiatry (2015) 1.39
Artificial neural network models for prediction of acute coronary syndromes using clinical data from the time of presentation. Ann Emerg Med (2005) 1.38
Youth consultation-liaison psychiatry: how can we improve outcomes for young people with chronic illness? Aust N Z J Psychiatry (2013) 1.38
A psychoneuroimmunological review on cytokines involved in antidepressant treatment response. Hum Psychopharmacol (2010) 1.30
Amygdala reactivity to masked negative faces is associated with automatic judgmental bias in major depression: a 3 T fMRI study. J Psychiatry Neurosci (2007) 1.22
Measurement of retinal vessel widths from fundus images based on 2-D modeling. IEEE Trans Med Imaging (2004) 1.19
Neuroplastic changes in depression: a role for the immune system. Psychoneuroendocrinology (2012) 1.19
Overweight and obesity at school entry among migrant and German children: a cross-sectional study. BMC Public Health (2005) 1.19
Reduced amygdala-prefrontal coupling in major depression: association with MAOA genotype and illness severity. Int J Neuropsychopharmacol (2008) 1.18
Depression and type 2 diabetes: inflammatory mechanisms of a psychoneuroendocrine co-morbidity. Neurosci Biobehav Rev (2011) 1.16
Childhood maltreatment is associated with an automatic negative emotion processing bias in the amygdala. Hum Brain Mapp (2012) 1.12
Psychosis in Indigenous populations of Cape York and the Torres Strait. Med J Aust (2012) 1.12
Systemic inflammation is associated with MCI and its subtypes: the Sydney Memory and Aging Study. Dement Geriatr Cogn Disord (2011) 1.12
The association between systemic inflammation and cognitive performance in the elderly: the Sydney Memory and Ageing Study. Age (Dordr) (2011) 1.09
Cross-disorder analysis of bipolar risk genes: further evidence of DGKH as a risk gene for bipolar disorder, but also unipolar depression and adult ADHD. Neuropsychopharmacology (2011) 1.07
Hydroxyoctadecadienoic acids: novel regulators of macrophage differentiation and atherogenesis. Ther Adv Endocrinol Metab (2010) 1.06
The circadian system in Alzheimer's disease: disturbances, mechanisms, and opportunities. Biol Psychiatry (2012) 1.06
Interindividual variation in anxiety response to amphetamine: possible role for adenosine A2A receptor gene variants. Am J Med Genet B Neuropsychiatr Genet (2005) 1.04
Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response. Int J Neuropsychopharmacol (2009) 1.02
Overweight, medical comorbidity and health-related quality of life in a community sample of women and men. Obesity (Silver Spring) (2009) 1.01
Working-memory fMRI reveals cingulate hyperactivation in euthymic major depression. Hum Brain Mapp (2009) 0.99
Emotion specific modulation of automatic amygdala responses by 5-HTTLPR genotype. Neuroimage (2009) 0.98
Neuropeptide Y (NPY) gene: Impact on emotional processing and treatment response in anxious depression. Eur Neuropsychopharmacol (2009) 0.98
Cannabinoid receptor 1 (CNR1) gene: impact on antidepressant treatment response and emotion processing in major depression. Eur Neuropsychopharmacol (2008) 0.97
Macrophage inhibitory cytokine-1 is associated with cognitive impairment and predicts cognitive decline - the Sydney Memory and Aging Study. Aging Cell (2013) 0.96
Association of MAO-A variant with complicated grief in major depression. Neuropsychobiology (2008) 0.95
Treating depression and depression-like behavior with physical activity: an immune perspective. Front Psychiatry (2013) 0.95
A review of the affects of worry and generalized anxiety disorder upon cardiovascular health and coronary heart disease. Psychol Health Med (2013) 0.95
Catechol-O-methyltransferase gene variation: impact on amygdala response to aversive stimuli. Neuroimage (2012) 0.95
The association between pulse wave velocity and cognitive function: the Sydney Memory and Ageing Study. PLoS One (2013) 0.94
Investigation of skeletal muscle quantity and quality in end-stage renal disease. Nephrology (Carlton) (2010) 0.92
Changes in insulin resistance and HbA1c are related to exercise-mediated changes in body composition in older adults with type 2 diabetes: interim outcomes from the GREAT2DO trial. Diabetes Care (2013) 0.92
Dementia: opportunities for risk reduction and early detection in general practice. Aust J Prim Health (2011) 0.91
Obesity and impairment in psychosocial functioning in women: the mediating role of eating disorder features. Obesity (Silver Spring) (2007) 0.90
Genome-wide association study of antidepressant treatment-emergent suicidal ideation. Neuropsychopharmacology (2011) 0.89
Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report. PLoS One (2013) 0.88
Comorbid anxiety disorders alter the association between cardiovascular diseases and depression: the German National Health Interview and Examination Survey. Soc Psychiatry Psychiatr Epidemiol (2013) 0.88
Effect of resistance training during hemodialysis on circulating cytokines: a randomized controlled trial. Eur J Appl Physiol (2010) 0.88
The role of the BDNF Val66Met polymorphism for the synchronization of error-specific neural networks. J Neurosci (2010) 0.88
Research review: the role of cytokines in depression in adolescents: a systematic review. J Child Psychol Psychiatry (2013) 0.87
Structural simplexity of the brain. J Neurosci Methods (2010) 0.87
Serotonin transporter gene methylation is associated with hippocampal gray matter volume. Hum Brain Mapp (2014) 0.87
Associations between preschool attendance and developmental impairments in pre-school children in a six-year retrospective survey. BMC Public Health (2006) 0.85
Longitudinal changes of day-time and night-time gross motor activity in clinical responders and non-responders of major depression. World J Biol Psychiatry (2009) 0.85
The hidden-Markov brain: comparison and inference of white matter hyperintensities on magnetic resonance imaging (MRI). J Neural Eng (2011) 0.85
Complicated grief in patients with unipolar depression. J Affect Disord (2009) 0.85
Variations in the TNF-α gene (TNF-α -308G→A) affect attention and action selection mechanisms in a dissociated fashion. J Neurophysiol (2010) 0.84
Norepinephrine and serotonin transporter genes: impact on treatment response in depression. Neuropsychobiology (2010) 0.84
Major depression and first-time hospitalization with ischemic heart disease, cardiac procedures and mortality in the general population: a retrospective Danish population-based cohort study. Eur J Prev Cardiol (2012) 0.84
Specifying the neuropsychology of affective disorders: clinical, demographic and neurobiological factors. Neuropsychol Rev (2011) 0.84
Reductions in C-reactive protein in older adults with type 2 diabetes are related to improvements in body composition following a randomized controlled trial of resistance training. J Cachexia Sarcopenia Muscle (2014) 0.84
TNF-α and its receptors modulate complex behaviours and neurotrophins in transgenic mice. Psychoneuroendocrinology (2013) 0.83
Dysbindin (DTNBP1)--a role in psychotic depression? J Psychiatr Res (2010) 0.82
The puzzle of predicting the impact of brain infarcts on cognitive impairment in the aging brain. Stroke (2009) 0.81
Brain-derived neurotrophic factor gene polymorphisms, neurotransmitter levels, and depressive symptoms in an elderly population. Age (Dordr) (2011) 0.81
Brain-derived neurotrophic factor (BDNF) gene: a gender-specific role in cognitive function during normal cognitive aging of the MEMO-Study? Age (Dordr) (2011) 0.81
HTR2A gene variation is involved in antidepressant treatment response. Eur Neuropsychopharmacol (2010) 0.81
Memory performance in severely depressed patients treated by electroconvulsive therapy. J ECT (2006) 0.80
The relationship between depressive symptoms and restless legs syndrome in two prospective cohort studies. Psychosom Med (2013) 0.80
Study of Mental Activity and Regular Training (SMART) in at risk individuals: a randomised double blind, sham controlled, longitudinal trial. BMC Geriatr (2011) 0.80
Hydroxyoctadecadienoic acids regulate apoptosis in human THP-1 cells in a PPARγ-dependent manner. Lipids (2014) 0.79
Pharmacoepigenetics of depression: no major influence of MAO-A DNA methylation on treatment response. J Neural Transm (Vienna) (2014) 0.79
Monoamine oxidase A variant influences antidepressant treatment response in female patients with Major Depression. Prog Neuropsychopharmacol Biol Psychiatry (2007) 0.79
KPNA3 variation is associated with schizophrenia, major depression, opiate dependence and alcohol dependence. Dis Markers (2012) 0.79
Adjunctive antidepressant treatment with quetiapine in agitated depression: positive effects on symptom reduction, psychopathology and remission rates. Hum Psychopharmacol (2008) 0.79
Dopamine D₃ receptor gene variation: impact on electroconvulsive therapy response and ventral striatum responsiveness in depression. Int J Neuropsychopharmacol (2011) 0.79
Dissociable influences of NR2B-receptor related neural transmission on functions of distinct associative basal ganglia circuits. Neuroimage (2010) 0.79
Cognitive impairment before and six months after cardiac surgery increase mortality risk at median 11 year follow-up: a cohort study. Int J Cardiol (2013) 0.78
Establishing the bidirectional relationship between depression and subclinical arteriosclerosis--rationale, design, and characteristics of the BiDirect Study. BMC Psychiatry (2014) 0.78
Neuroimmunomodulation in unipolar depression: a focus on chronobiology and chronotherapeutics. J Neural Transm (Vienna) (2012) 0.78
Adiposity estimated using dual energy X-ray absorptiometry and body mass index and its association with cognition in elderly adults. J Am Geriatr Soc (2014) 0.78
Night locomotor activity and quality of sleep in quetiapine-treated patients with depression. J Clin Psychopharmacol (2006) 0.78
Obesity and nutrition behaviours in Western and Palestinian outpatients with severe mental illness. BMC Psychiatry (2011) 0.78
COMT val158met influence on electroconvulsive therapy response in major depression. Am J Med Genet B Neuropsychiatr Genet (2010) 0.78
Elevated neutrophil to lymphocyte ratio predicts mortality in medical inpatients with multiple chronic conditions. Medicine (Baltimore) (2016) 0.77
Poor Self-Rated Health Influences Hospital Service Use in Hospitalized Inpatients With Chronic Conditions in Taiwan. Medicine (Baltimore) (2015) 0.77
Evidence of increased risk for major depressive disorder in individuals homozygous for the high-expressing 5-HTTLPR/rs25531 (L(A)) allele of the serotonin transporter promoter. Psychiatr Genet (2013) 0.76
Gene expression in the aging human brain: an overview. Curr Opin Psychiatry (2016) 0.76
A case of multiple sclerosis masked by depression and diabetic neuropathy. Psychosomatics (2006) 0.76
Implicit and explicit procedural learning in patients recently remitted from severe major depression. Psychiatry Res (2009) 0.75
Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach. PLoS One (2013) 0.75
Recurrence of suicidal ideation due to treatment with antidepressants in anxiety disorder: a case report. J Med Case Rep (2007) 0.75
Prevalence and risk factors of syphilis infection among drug addicts. BMC Infect Dis (2005) 0.75
Double dissociated effects of the functional TNF-α -308G/A polymorphism on processes of cognitive control. Neuropsychologia (2010) 0.75
Therapeutic perspective: starting an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker in a diabetic patient. Ther Adv Endocrinol Metab (2010) 0.75
Cognitive dysfunction in major depressive disorder. Curr Opin Psychiatry (2017) 0.75
Automatic covariate selection in logistic models for chest pain diagnosis: a new approach. Comput Methods Programs Biomed (2007) 0.75
Health service utilization in patients with major depression and co-morbid pain. Psychiatry Clin Neurosci (2008) 0.75
Body temperature in patients with panic disorder treated with escitalopram. Clin Auton Res (2009) 0.75
Fingolimod exacerbated affective psychosis? Aust N Z J Psychiatry (2012) 0.75
Differentiating disordered affect in children and adolescents with type 1 diabetes. J Affect Disord (2012) 0.75
Youth hub-and-spoke model. Aust N Z J Psychiatry (2013) 0.75
[Suicides and social neighbourhood characteristics: an ecological analysis in an urban German area]. Psychiatr Prax (2009) 0.75
Preprocessing film-copied MRI for studying morphological brain changes. J Neurosci Methods (2009) 0.75
Detecting psychotic symptoms in Indigenous populations: a review of available assessment tools. Schizophr Res (2012) 0.75
Auditory processing of sine tones before, during and after ECT in depressed patients by fMRI. J Neural Transm (Vienna) (2008) 0.75