Published in Cell on September 19, 2008
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell (2010) 10.96
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab (2010) 5.82
A genome-wide perspective of genetic variation in human metabolism. Nat Genet (2009) 5.00
Lipid-induced insulin resistance: unravelling the mechanism. Lancet (2010) 4.88
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature (2011) 4.78
What we talk about when we talk about fat. Cell (2014) 4.12
The plasma lipidomic signature of nonalcoholic steatohepatitis. Hepatology (2009) 3.48
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis. Nat Med (2009) 3.43
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature (2012) 3.41
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature (2012) 3.35
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Mol Cell (2011) 3.33
Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell (2014) 3.03
Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab (2012) 2.96
FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling. Cell Metab (2012) 2.96
Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes (2009) 2.68
Trans-palmitoleic acid, metabolic risk factors, and new-onset diabetes in U.S. adults: a cohort study. Ann Intern Med (2010) 2.48
GOAT links dietary lipids with the endocrine control of energy balance. Nat Med (2009) 2.42
Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses. Cell (2012) 2.38
The human plasma lipidome. N Engl J Med (2011) 2.35
Biochemical and physiological function of stearoyl-CoA desaturase. Am J Physiol Endocrinol Metab (2008) 2.28
Palmitate induces insulin resistance in H4IIEC3 hepatocytes through reactive oxygen species produced by mitochondria. J Biol Chem (2009) 2.21
Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice. J Biol Chem (2010) 2.14
The inflammation highway: metabolism accelerates inflammatory traffic in obesity. Immunol Rev (2012) 2.01
Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit Rev Biochem Mol Biol (2010) 1.89
Energy metabolism in the liver. Compr Physiol (2014) 1.88
Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells. FASEB J (2009) 1.79
Endoplasmic reticulum stress and atherosclerosis. Nat Med (2010) 1.78
Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. Cell (2011) 1.76
Adipocyte CREB promotes insulin resistance in obesity. Cell Metab (2009) 1.72
Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates. Am J Physiol Endocrinol Metab (2009) 1.70
A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use. Nature (2013) 1.69
T-ing up inflammation in fat. Nat Med (2009) 1.66
Brain insulin controls adipose tissue lipolysis and lipogenesis. Cell Metab (2011) 1.64
The relationship between high-fat dairy consumption and obesity, cardiovascular, and metabolic disease. Eur J Nutr (2012) 1.58
Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis. J Hepatol (2010) 1.56
Structural and functional analysis of fatty acid-binding proteins. J Lipid Res (2008) 1.56
Circulating palmitoleic acid and risk of metabolic abnormalities and new-onset diabetes. Am J Clin Nutr (2010) 1.55
Tissue-specific functions in the fatty acid-binding protein family. J Biol Chem (2010) 1.52
Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice. Cell Metab (2015) 1.51
Adipocytokines in obesity and metabolic disease. J Endocrinol (2014) 1.49
Label-free quantitative analysis of lipid metabolism in living Caenorhabditis elegans. J Lipid Res (2009) 1.41
Gr-1+ CD11b+ myeloid-derived suppressor cells suppress inflammation and promote insulin sensitivity in obesity. J Biol Chem (2011) 1.37
The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux. J Clin Invest (2016) 1.37
Circulating palmitoleate strongly and independently predicts insulin sensitivity in humans. Diabetes Care (2009) 1.36
Mechanisms of lipotoxicity in NAFLD and clinical implications. J Pediatr Gastroenterol Nutr (2011) 1.35
Atf4 regulates obesity, glucose homeostasis, and energy expenditure. Diabetes (2009) 1.34
Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation. Proc Natl Acad Sci U S A (2009) 1.33
Fatty acids identified in the Burmese python promote beneficial cardiac growth. Science (2011) 1.30
trans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr (2013) 1.28
Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes. PLoS One (2012) 1.28
Integrated metabolite and gene expression profiles identify lipid biomarkers associated with progression of hepatocellular carcinoma and patient outcomes. Gastroenterology (2013) 1.27
Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation. PLoS One (2012) 1.27
Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity. Biochim Biophys Acta (2009) 1.27
Transcription factor Nrf2 regulates SHP and lipogenic gene expression in hepatic lipid metabolism. Am J Physiol Gastrointest Liver Physiol (2010) 1.27
Integration of clinical data with a genome-scale metabolic model of the human adipocyte. Mol Syst Biol (2013) 1.26
Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation. J Biol Chem (2010) 1.26
Pigment epithelium-derived factor regulates lipid metabolism via adipose triglyceride lipase. Diabetes (2011) 1.25
Chronic administration of palmitoleic acid reduces insulin resistance and hepatic lipid accumulation in KK-Ay Mice with genetic type 2 diabetes. Lipids Health Dis (2011) 1.25
Palmitoleate induces hepatic steatosis but suppresses liver inflammatory response in mice. PLoS One (2012) 1.23
NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids. Cell (2013) 1.22
Clock genes, intestinal transport and plasma lipid homeostasis. Trends Endocrinol Metab (2009) 1.21
The role of hepatokines in metabolism. Nat Rev Endocrinol (2013) 1.21
De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health. Nat Commun (2013) 1.20
Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production. Cell Metab (2013) 1.19
Fatty Acid-Binding Protein 4 (FABP4): Pathophysiological Insights and Potent Clinical Biomarker of Metabolic and Cardiovascular Diseases. Clin Med Insights Cardiol (2015) 1.19
Biology of upper-body and lower-body adipose tissue--link to whole-body phenotypes. Nat Rev Endocrinol (2014) 1.18
Metabolically normal obese people are protected from adverse effects following weight gain. J Clin Invest (2015) 1.17
A Western-like fat diet is sufficient to induce a gradual enhancement in fat mass over generations. J Lipid Res (2010) 1.15
Lipoexpediency: de novo lipogenesis as a metabolic signal transmitter. Trends Endocrinol Metab (2011) 1.14
Brown fat fuel utilization and thermogenesis. Trends Endocrinol Metab (2014) 1.12
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Circ Cardiovasc Genet (2013) 1.12
Role of fatty acid elongases in determination of de novo synthesized monounsaturated fatty acid species. J Lipid Res (2010) 1.12
Defining the metabolome: size, flux, and regulation. Mol Cell (2015) 1.11
A critical role for PKR complexes with TRBP in Immunometabolic regulation and eIF2α phosphorylation in obesity. Cell Rep (2015) 1.11
Effects of sample handling and storage on quantitative lipid analysis in human serum. Metabolomics (2009) 1.11
A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats. Am J Physiol Endocrinol Metab (2010) 1.10
Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins. Cell Rep (2013) 1.09
Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation. J Lipid Res (2014) 1.08
Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways. Nat Med (2012) 1.07
Yin and Yang of hypothalamic insulin and leptin signaling in regulating white adipose tissue metabolism. Rev Endocr Metab Disord (2011) 1.07
Free fatty acid receptors: emerging targets for treatment of diabetes and its complications. Ther Adv Endocrinol Metab (2010) 1.06
Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues. Nat Commun (2015) 1.06
Getting biological about the genetics of diabetes. Nat Med (2010) 1.05
High-fat diet leads to tissue-specific changes reflecting risk factors for diseases in DBA/2J mice. Physiol Genomics (2010) 1.05
IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal. Circ Res (2012) 1.04
Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate. Arterioscler Thromb Vasc Biol (2009) 1.04
Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis. J Lipid Res (2010) 1.04
Gluteofemoral adipose tissue plays a major role in production of the lipokine palmitoleate in humans. Diabetes (2012) 1.04
Lipid chaperones and metabolic inflammation. Int J Inflam (2011) 1.03
Nutritional lipidomics: molecular metabolism, analytics, and diagnostics. Mol Nutr Food Res (2013) 1.03
A novel function of adipocytes in lipid antigen presentation to iNKT cells. Mol Cell Biol (2012) 1.03
Fatty acid- and retinoid-binding proteins have distinct binding pockets for the two types of cargo. J Biol Chem (2009) 1.02
MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice. J Clin Invest (2009) 1.01
Oxidative stress and the ageing endocrine system. Nat Rev Endocrinol (2013) 1.00
Adipose tissue palmitoleic acid and obesity in humans: does it behave as a lipokine? Am J Clin Nutr (2010) 1.00
Analysis of porcine adipose tissue transcriptome reveals differences in de novo fatty acid synthesis in pigs with divergent muscle fatty acid composition. BMC Genomics (2013) 1.00
Insulin signalling mechanisms for triacylglycerol storage. Diabetologia (2013) 1.00
Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion. Diabetes (2011) 0.98
A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem (1957) 173.99
Inflammation and metabolic disorders. Nature (2006) 33.33
Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol (1963) 29.15
The metabolic syndrome. Lancet (2005) 19.47
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem (2002) 9.76
Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest (2007) 8.71
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets. Nat Rev Drug Discov (2008) 5.78
Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science (1996) 4.61
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature (2007) 4.59
PKC-theta knockout mice are protected from fat-induced insulin resistance. J Clin Invest (2004) 3.86
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab (2005) 3.51
Regulation of stearoyl-CoA desaturases and role in metabolism. Prog Lipid Res (2004) 3.14
Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J Lipid Res (1999) 2.89
The expression of adipogenic genes is decreased in obesity and diabetes mellitus. Proc Natl Acad Sci U S A (2000) 2.82
Free fatty acids and pathogenesis of type 2 diabetes mellitus. Trends Endocrinol Metab (2000) 2.69
A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease. Proc Natl Acad Sci U S A (2006) 2.41
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression. Cell Metab (2007) 2.32
Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone. J Lipid Res (2002) 2.30
Fatty acid composition of serum lipids predicts the development of the metabolic syndrome in men. Diabetologia (2005) 2.07
Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice. Hepatology (2006) 2.01
Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation. Mol Cell Biol (2006) 1.90
The insulinotropic potency of fatty acids is influenced profoundly by their chain length and degree of saturation. J Clin Invest (1997) 1.89
Metabolic syndrome: focus on dyslipidemia. Obesity (Silver Spring) (2006) 1.80
Lipid and lipoprotein dysregulation in insulin resistant states. Clin Chim Acta (2006) 1.73
Study of the alteration of gene expression in adipose tissue of diet-induced obese mice by microarray and reverse transcription-polymerase chain reaction analyses. Endocrinology (2003) 1.63
Regulation of metabolic responses by adipocyte/macrophage Fatty Acid-binding proteins in leptin-deficient mice. Diabetes (2006) 1.56
Plasma palmitoleic acid, a product of stearoyl-coA desaturase activity, is an independent marker of triglyceridemia and abdominal adiposity. Nutr Metab Cardiovasc Dis (2008) 1.46
Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver. Cell Metab (2005) 1.34
Differential effects of phosphatidylinositol 3-kinase inhibition on intracellular signals regulating GLUT4 translocation and glucose transport. J Biol Chem (2001) 1.22
Stearoyl-CoA desaturase, a short-lived protein of endoplasmic reticulum with multiple control mechanisms. Prostaglandins Leukot Essent Fatty Acids (2003) 1.21
Serum lipid effects of a monounsaturated (palmitoleic) fatty acid-rich diet based on macadamia nuts in healthy, young Japanese women. Clin Exp Pharmacol Physiol (2004) 1.05
Localization of a polyunsaturated fatty acid response region in stearoyl-CoA desaturase gene 1. Biochim Biophys Acta (1997) 1.00
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science (2004) 19.08
A central role for JNK in obesity and insulin resistance. Nature (2002) 17.27
Inflammation, stress, and diabetes. J Clin Invest (2005) 17.11
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science (2006) 13.91
Inflammatory mechanisms in obesity. Annu Rev Immunol (2011) 9.83
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell (2010) 8.69
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat Med (2011) 6.15
Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance. Cell Metab (2010) 5.82
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets. Nat Rev Drug Discov (2008) 5.78
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature (2011) 4.78
Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2. Nature (2007) 4.59
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell (2010) 4.01
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med (2009) 3.97
Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. J Lipid Res (2007) 3.96
Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis. Mol Cell (2008) 3.91
A lipidomic analysis of nonalcoholic fatty liver disease. Hepatology (2007) 3.65
Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab (2005) 3.51
The plasma lipidomic signature of nonalcoholic steatohepatitis. Hepatology (2009) 3.48
Endoplasmic reticulum stress is reduced in tissues of obese subjects after weight loss. Diabetes (2008) 3.47
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis. Nat Med (2009) 3.43
Lipopenia and skin barrier abnormalities in DGAT2-deficient mice. J Biol Chem (2003) 3.19
Novel role of PKR in inflammasome activation and HMGB1 release. Nature (2012) 3.13
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance. Proc Natl Acad Sci U S A (2006) 3.02
Metabolomics: building on a century of biochemistry to guide human health. Metabolomics (2005) 3.01
Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways. Cell Metab (2011) 2.91
Adipocyte/macrophage fatty acid-binding proteins contribute to metabolic deterioration through actions in both macrophages and adipocytes in mice. J Clin Invest (2008) 2.55
Habitual dietary intake of n-3 and n-6 fatty acids in relation to inflammatory markers among US men and women. Circulation (2003) 2.52
Trans-palmitoleic acid, metabolic risk factors, and new-onset diabetes in U.S. adults: a cohort study. Ann Intern Med (2010) 2.48
Tumor necrosis factor alpha-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling. Cell Metab (2006) 2.43
Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis. Cell (2007) 2.35
Endoplasmic reticulum stress and inflammation in obesity and diabetes. Circ Res (2010) 2.20
Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice. J Biol Chem (2010) 2.14
Tauroursodeoxycholic Acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes (2010) 2.10
The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling. Cell Metab (2012) 2.04
Adipose acyl-CoA synthetase-1 directs fatty acids toward beta-oxidation and is required for cold thermogenesis. Cell Metab (2010) 2.00
Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses. J Nutr (2004) 2.00
Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance. Gastroenterology (2006) 1.97
Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia. Arterioscler Thromb Vasc Biol (2002) 1.94
Interaction between GATA and the C/EBP family of transcription factors is critical in GATA-mediated suppression of adipocyte differentiation. Mol Cell Biol (2005) 1.92
A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity. PLoS One (2008) 1.90
Role of the fatty acid binding protein mal1 in obesity and insulin resistance. Diabetes (2003) 1.88
The interaction of hepatic lipid and glucose metabolism in liver diseases. J Hepatol (2011) 1.87
Exclusive action of transmembrane TNF alpha in adipose tissue leads to reduced adipose mass and local but not systemic insulin resistance. Endocrinology (2002) 1.80
Adiponectin: stability in plasma over 36 hours and within-person variation over 1 year. Clin Chem (2003) 1.70
A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use. Nature (2013) 1.69
Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells. Nat Commun (2013) 1.68
Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity. J Lipid Res (2006) 1.68
Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium. J Lipid Res (2006) 1.62
Combined adipocyte-macrophage fatty acid-binding protein deficiency improves metabolism, atherosclerosis, and survival in apolipoprotein E-deficient mice. Circulation (2004) 1.60
Dual and opposing roles of the unfolded protein response regulated by IRE1alpha and XBP1 in proinsulin processing and insulin secretion. Proc Natl Acad Sci U S A (2011) 1.59
Lipidomics and lipid profiling in metabolomics. Curr Opin Lipidol (2007) 1.58
Regulation of metabolic responses by adipocyte/macrophage Fatty Acid-binding proteins in leptin-deficient mice. Diabetes (2006) 1.56
Circulating palmitoleic acid and risk of metabolic abnormalities and new-onset diabetes. Am J Clin Nutr (2010) 1.55
Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy. Mol Cell Biol (2011) 1.55
Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes. Sci Transl Med (2013) 1.55
Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition. J Biol Chem (2009) 1.54
The adipocyte fatty acid-binding protein aP2 is required in allergic airway inflammation. J Clin Invest (2006) 1.54
The role of fatty acid binding proteins in metabolic syndrome and atherosclerosis. Curr Opin Lipidol (2005) 1.53
Small-molecule inhibitors of PKR improve glucose homeostasis in obese diabetic mice. Diabetes (2013) 1.50
Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis. Cell Metab (2006) 1.50
Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism. Cancer Res (2013) 1.49
Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers. Obes Res (2003) 1.34
Regulation of dendritic cell function and T cell priming by the fatty acid-binding protein AP2. J Immunol (2006) 1.31
Enteric microbiome metabolites correlate with response to simvastatin treatment. PLoS One (2011) 1.31
Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study. Metabolomics (2010) 1.29
Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders. Proc Natl Acad Sci U S A (2012) 1.26
Divergent roles for p55 and p75 TNF-alpha receptors in the induction of plasminogen activator inhibitor-1. Am J Pathol (2003) 1.25
Deficiency of fatty acid-binding proteins in mice confers protection from development of experimental autoimmune encephalomyelitis. J Immunol (2007) 1.25
Adipocyte lipid chaperone AP2 is a secreted adipokine regulating hepatic glucose production. Cell Metab (2013) 1.19
Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity. Diabetes (2002) 1.19
Serum fatty acid-binding protein 4 is a predictor of cardiovascular events in end-stage renal disease. PLoS One (2011) 1.13
Effects of sample handling and storage on quantitative lipid analysis in human serum. Metabolomics (2009) 1.11
Interaction of tumor necrosis factor-alpha- and thiazolidinedione-regulated pathways in obesity. Endocrinology (2004) 1.09
The role of JNK proteins in metabolism. Sci Transl Med (2010) 1.09
Linking the inflammasome to obesity-related disease. Nat Med (2011) 1.05
Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices. J Clin Endocrinol Metab (2003) 1.02
Genomics and metabolomics as markers for the interaction of diet and health: lessons from lipids. J Nutr (2003) 1.02
Mice deficient in mitochondrial glycerol-3-phosphate acyltransferase-1 have diminished myocardial triacylglycerol accumulation during lipogenic diet and altered phospholipid fatty acid composition. Biochim Biophys Acta (2008) 1.01
Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting. PLoS Genet (2012) 1.01
Assessing individual metabolic responsiveness to a lipid challenge using a targeted metabolomic approach. Metabolomics (2009) 1.00
Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase. Am J Physiol Endocrinol Metab (2009) 1.00
Metabolomic profiles and childhood obesity. Obesity (Silver Spring) (2014) 1.00
Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice. Arterioscler Thromb Vasc Biol (2011) 0.99
FABP4 attenuates PPARγ and adipogenesis and is inversely correlated with PPARγ in adipose tissues. Diabetes (2013) 0.98
Stressing the brain, fattening the body. Cell (2008) 0.96