The effort to make mosaic analysis a household tool.

PubWeight™: 0.87‹?›

🔗 View Article (PMC 3509720)

Published in Development on December 01, 2012

Authors

Tian Xu1, Gerald M Rubin

Author Affiliations

1: Department of Genetics, Howard Hughes Medical Institute, Yale University School of Medicine, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06510, USA. tian.xu@yale.edu

Articles cited by this

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (1993) 58.26

Genetic transformation of Drosophila with transposable element vectors. Science (1982) 27.36

Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature (1961) 23.98

Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis. Neuron (1999) 17.62

Analysis of genetic mosaics in developing and adult Drosophila tissues. Development (1993) 13.43

Somatic Crossing over and Segregation in Drosophila Melanogaster. Genetics (1936) 13.41

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell (2005) 10.61

The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell (1989) 8.93

Akt regulates growth by directly phosphorylating Tsc2. Nat Cell Biol (2002) 8.04

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell (2003) 6.48

The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics (1996) 5.72

Mosaic analysis with double markers in mice. Cell (2005) 5.32

Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development (1995) 5.18

A niche maintaining germ line stem cells in the Drosophila ovary. Science (2000) 5.04

Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell (2001) 4.98

Mapping of behaviour in Drosophila mosaics. Nature (1972) 4.41

decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell (1998) 4.18

A genetic screen in Drosophila for metastatic behavior. Science (2003) 4.09

Drosophila myc regulates organ size by inducing cell competition. Cell (2004) 3.98

The choice of cell fate in the epidermis of Drosophila. Cell (1991) 3.71

Site-specific recombination between homologous chromosomes in Drosophila. Science (1991) 3.70

dMyc transforms cells into super-competitors. Cell (2004) 3.66

A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype. Genetics (1999) 3.54

Cell lineage of the imaginal discs in Drosophila gynandromorphs. J Exp Zool (1969) 2.79

PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Development (1999) 2.56

Twin-spot MARCM to reveal the developmental origin and identity of neurons. Nat Neurosci (2009) 2.26

Engulfment is required for cell competition. Cell (2007) 1.65

Modeling sporadic loss of heterozygosity in mice by using mosaic analysis with double markers (MADM). Proc Natl Acad Sci U S A (2007) 1.29

Induced mitotic recombination of p53 in vivo. Proc Natl Acad Sci U S A (2007) 1.18

The identification of novel genes required for Drosophila anteroposterior axis formation in a germline clone screen using GFP-Staufen. Development (2003) 1.17

A mitotic recombination system for mouse chromosome 17. Proc Natl Acad Sci U S A (2008) 0.93

Development of the Drosophila retina: inductive events studied at single cell resolution. Cell (1989) 0.93

Pointing a digit at digitised JEEM. Development (2008) 0.77

Articles by these authors

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A (2002) 20.48

Computational identification of Drosophila microRNA genes. Genome Biol (2003) 9.86

Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster. Science (2002) 9.43

Evidence for large domains of similarly expressed genes in the Drosophila genome. J Biol (2002) 9.31

Systematic determination of patterns of gene expression during Drosophila embryogenesis. Genome Biol (2002) 8.89

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review. Genome Biol (2002) 8.59

Exploiting transcription factor binding site clustering to identify cis-regulatory modules involved in pattern formation in the Drosophila genome. Proc Natl Acad Sci U S A (2002) 8.56

The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics (2004) 8.40

Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence. Genome Biol (2002) 8.07

The Drosophila gene collection: identification of putative full-length cDNAs for 70% of D. melanogaster genes. Genome Res (2002) 6.61

Tools for neuroanatomy and neurogenetics in Drosophila. Proc Natl Acad Sci U S A (2008) 6.35

Global analysis of patterns of gene expression during Drosophila embryogenesis. Genome Biol (2007) 6.27

The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective. Genome Biol (2002) 5.80

Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs. Genes Dev (2005) 5.78

Computational analysis of core promoters in the Drosophila genome. Genome Biol (2002) 5.60

Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. Genome Biol (2002) 5.09

A GAL4-driver line resource for Drosophila neurobiology. Cell Rep (2012) 4.67

The Toll and Imd pathways are the major regulators of the immune response in Drosophila. EMBO J (2002) 4.63

Refinement of tools for targeted gene expression in Drosophila. Genetics (2010) 4.53

Targeted mutagenesis by homologous recombination in D. melanogaster. Genes Dev (2002) 4.21

A visual motion detection circuit suggested by Drosophila connectomics. Nature (2013) 3.94

A Drosophila full-length cDNA resource. Genome Biol (2002) 3.67

Computational identification of developmental enhancers: conservation and function of transcription factor binding-site clusters in Drosophila melanogaster and Drosophila pseudoobscura. Genome Biol (2004) 3.36

The Drosophila melanogaster genome. Annu Rev Genomics Hum Genet (2003) 3.18

Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome. Genome Biol (2002) 3.09

ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos. Proc Natl Acad Sci U S A (2002) 3.09

Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage. Mol Cell Biol (2004) 2.75

Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development. Proc Natl Acad Sci U S A (2005) 2.62

A directional tuning map of Drosophila elementary motion detectors. Nature (2013) 2.53

Large-scale trends in the evolution of gene structures within 11 animal genomes. PLoS Comput Biol (2006) 2.42

Identification of putative noncoding polyadenylated transcripts in Drosophila melanogaster. Proc Natl Acad Sci U S A (2005) 2.30

A subset of dopamine neurons signals reward for odour memory in Drosophila. Nature (2012) 2.20

Using translational enhancers to increase transgene expression in Drosophila. Proc Natl Acad Sci U S A (2012) 1.98

Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development. Dev Cell (2003) 1.88

Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development. Curr Biol (2003) 1.76

Complementary miRNA pairs suggest a regulatory role for miRNA:miRNA duplexes. RNA (2004) 1.63

A resource for manipulating gene expression and analyzing cis-regulatory modules in the Drosophila CNS. Cell Rep (2012) 1.62

Nurturing interdisciplinary research. Nat Struct Mol Biol (2004) 1.61

The ubiquitin ligase Drosophila Mind bomb promotes Notch signaling by regulating the localization and activity of Serrate and Delta. Development (2005) 1.55

Mushroom body efferent neurons responsible for aversive olfactory memory retrieval in Drosophila. Nat Neurosci (2011) 1.53

Y chromosome and other heterochromatic sequences of the Drosophila melanogaster genome: how far can we go? Genetica (2003) 1.49

A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome. Proc Natl Acad Sci U S A (2005) 1.46

A survey of 6,300 genomic fragments for cis-regulatory activity in the imaginal discs of Drosophila melanogaster. Cell Rep (2012) 1.39

Global analyses of mRNA translational control during early Drosophila embryogenesis. Genome Biol (2007) 1.30

Contributions of the 12 neuron classes in the fly lamina to motion vision. Neuron (2013) 1.25

Multiple new site-specific recombinases for use in manipulating animal genomes. Proc Natl Acad Sci U S A (2011) 1.23

Cathepsin D-deficient Drosophila recapitulate the key features of neuronal ceroid lipofuscinoses. Neurobiol Dis (2005) 1.15

Neuroarchitecture and neuroanatomy of the Drosophila central complex: A GAL4-based dissection of protocerebral bridge neurons and circuits. J Comp Neurol (2014) 1.01

Defining the mandate of proteomics in the post-genomics era: workshop report. Mol Cell Proteomics (2002) 0.95

Quick preparation of genomic DNA from Drosophila. Cold Spring Harb Protoc (2009) 0.95

The Ca(2+)-calmodulin-activated protein phosphatase calcineurin negatively regulates EGF receptor signaling in Drosophila development. Genetics (2002) 0.94

The Drosophila synaptotagmin-like protein bitesize is required for growth and has mRNA localization sequences within its open reading frame. Proc Natl Acad Sci U S A (2003) 0.93

Recovery of DNA sequences flanking P-element insertions in Drosophila: inverse PCR and plasmid rescue. Cold Spring Harb Protoc (2009) 0.88