Published in FASEB J on November 27, 2012
Approaches for analyzing the roles of mast cells and their proteases in vivo. Adv Immunol (2015) 0.85
Evidence that meningeal mast cells can worsen stroke pathology in mice. Am J Pathol (2014) 0.80
Mast cells promote blood brain barrier breakdown and neutrophil infiltration in a mouse model of focal cerebral ischemia. J Cereb Blood Flow Metab (2015) 0.76
Cell-Based Delivery of Interleukin-13 Directs Alternative Activation of Macrophages Resulting in Improved Functional Outcome after Spinal Cord Injury. Stem Cell Reports (2016) 0.75
Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis. Mediators Inflamm (2016) 0.75
Increased Bone Mass in Female Mice Lacking Mast Cell Chymase. PLoS One (2016) 0.75
Icatibant, a new bradykinin-receptor antagonist, in hereditary angioedema. N Engl J Med (2010) 2.98
Mast cells can enhance resistance to snake and honeybee venoms. Science (2006) 2.72
IL-15 constrains mast cell-dependent antibacterial defenses by suppressing chymase activities. Nat Med (2007) 2.00
High-dose desloratadine decreases wheal volume and improves cold provocation thresholds compared with standard-dose treatment in patients with acquired cold urticaria: a randomized, placebo-controlled, crossover study. J Allergy Clin Immunol (2009) 1.98
WAO Guideline for the Management of Hereditary Angioedema. World Allergy Organ J (2012) 1.96
Omalizumab in patients with symptomatic chronic idiopathic/spontaneous urticaria despite standard combination therapy. J Allergy Clin Immunol (2013) 1.91
Mast cells promote homeostasis by limiting endothelin-1-induced toxicity. Nature (2004) 1.91
A beneficial role for immunoglobulin E in host defense against honeybee venom. Immunity (2013) 1.71
A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2. J Biol Chem (2004) 1.70
A randomized, placebo-controlled, dose-ranging study of single-dose omalizumab in patients with H1-antihistamine-refractory chronic idiopathic urticaria. J Allergy Clin Immunol (2011) 1.64
Frequency and clinical implications of skin autoreactivity to serum versus plasma in patients with chronic urticaria. J Allergy Clin Immunol (2009) 1.60
Diagnosis and treatment of urticaria and angioedema: a worldwide perspective. World Allergy Organ J (2012) 1.58
Substance P as an immunomodulatory neuropeptide in a mouse model for autoimmune hair loss (alopecia areata). J Invest Dermatol (2007) 1.54
Neurophysiological, neuroimmunological, and neuroendocrine basis of pruritus. J Invest Dermatol (2006) 1.53
IL-9 production by regulatory T cells recruits mast cells that are essential for regulatory T cell-induced immune suppression. J Immunol (2010) 1.52
Desloratadine inhibits human skin mast cell activation and histamine release. J Invest Dermatol (2009) 1.51
Peltier effect-based temperature challenge: an improved method for diagnosing cold urticaria. J Allergy Clin Immunol (2004) 1.51
Mast cells are required for normal healing of skin wounds in mice. FASEB J (2006) 1.50
Effects of a pseudoallergen-free diet on chronic spontaneous urticaria: a prospective trial. Allergy (2009) 1.49
Mast cells--key effector cells in immune responses. Trends Immunol (2007) 1.48
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation (2009) 1.43
T cell killing by tolerogenic dendritic cells protects mice from allergy. J Clin Invest (2011) 1.41
TLR3-induced activation of mast cells modulates CD8+ T-cell recruitment. Blood (2005) 1.39
Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism. Proc Natl Acad Sci U S A (2009) 1.34
Serglycin is essential for maturation of mast cell secretory granule. J Biol Chem (2004) 1.32
Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation. EMBO J (2003) 1.27
Migration of melanoblasts into the developing murine hair follicle is accompanied by transient c-Kit expression. J Histochem Cytochem (2002) 1.26
Intracellular proteoglycans. Biochem J (2004) 1.25
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis. Nat Med (2008) 1.23
Skin mast cells control T cell-dependent host defense in Leishmania major infections. FASEB J (2006) 1.21
A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Blood (2010) 1.20
International consensus on hereditary and acquired angioedema. Ann Allergy Asthma Immunol (2012) 1.17
Role of mast cells in experimental anti-glomerular basement membrane glomerulonephritis. Eur J Immunol (2005) 1.16
Neutrophil elastase depends on serglycin proteoglycan for localization in granules. Blood (2007) 1.16
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice. J Clin Invest (2011) 1.16
Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation. J Immunol (2009) 1.15
Anti-immunoglobulin E treatment of patients with recalcitrant physical urticaria. Int Arch Allergy Immunol (2010) 1.15
Physical urticaria. Curr Allergy Asthma Rep (2012) 1.14
Increased levels of hypoxia-sensitive proteins in allergic airway inflammation. Am J Respir Crit Care Med (2004) 1.11
Serglycin: a structural and functional chameleon with wide impact on immune cells. J Immunol (2011) 1.11
IgE mediated autoallergy against thyroid peroxidase--a novel pathomechanism of chronic spontaneous urticaria? PLoS One (2011) 1.10
Visuospatial priming of the mental number line. Cognition (2007) 1.10
Control of Pseudomonas aeruginosa skin infections in mice is mast cell-dependent. Am J Pathol (2007) 1.10
Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage. J Biol Chem (2005) 1.09
Immediate contact skin reactions, an update of Contact Urticaria, Contact Urticaria Syndrome and Protein Contact Dermatitis -- "A Never Ending Story". Eur J Dermatol (2010) 1.09
A 29-amino acid fragment of Clostridium botulinum C3 protein enhances neuronal outgrowth, connectivity, and reinnervation. FASEB J (2008) 1.08
Urticaria: current opinions about etiology, diagnosis and therapy. Acta Derm Venereol (2007) 1.07
Homozygous mutations in IHH cause acrocapitofemoral dysplasia, an autosomal recessive disorder with cone-shaped epiphyses in hands and hips. Am J Hum Genet (2003) 1.07
Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan. J Allergy Clin Immunol (2008) 1.07
Biology of mast cell tryptase. An inflammatory mediator. FEBS J (2006) 1.06
Biological implications of preformed mast cell mediators. Cell Mol Life Sci (2010) 1.06
Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II. J Biol Chem (2004) 1.05
Hereditary angioedema with C1 inhibitor deficiency: delay in diagnosis in Europe. Allergy Asthma Clin Immunol (2013) 1.05
Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines. Proc Natl Acad Sci U S A (2012) 1.05
Pathophysiology of itch and new treatments. Curr Opin Allergy Clin Immunol (2011) 1.04
Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions. J Biol Chem (2007) 1.04
Mast cells promote Th1 and Th17 responses by modulating dendritic cell maturation and function. Eur J Immunol (2011) 1.04
Serglycin proteoglycan is required for secretory granule integrity in mucosal mast cells. Biochem J (2007) 1.03
Omalizumab in chronic urticaria. Curr Opin Allergy Clin Immunol (2012) 1.03
Murine mast cells secrete a unique profile of cytokines and prostaglandins in response to distinct TLR2 ligands. Exp Dermatol (2009) 1.02
Serglycin is the major secreted proteoglycan in macrophages and has a role in the regulation of macrophage tumor necrosis factor-alpha secretion in response to lipopolysaccharide. J Biol Chem (2006) 1.02
Physical urticarias and cholinergic urticaria. Immunol Allergy Clin North Am (2013) 1.02
Serglycin: the master of the mast cell. Methods Mol Biol (2012) 1.01
Mast cell functions in the innate skin immune system. Immunobiology (2007) 1.01
Innate immunity and allergy in the skin. Curr Opin Immunol (2009) 1.00
Mast cells: makers and breakers of allergic inflammation. Curr Opin Allergy Clin Immunol (2009) 1.00
Effector and potential immunoregulatory roles of mast cells in IgE-associated acquired immune responses. Curr Opin Immunol (2006) 0.99
Human mast cell beta-tryptase is a gelatinase. J Immunol (2003) 0.99
Kit is expressed by epithelial cells in vivo. J Invest Dermatol (2003) 0.98
Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis. J Immunol (2010) 0.97
Synergistic up-regulation of MCP-2/CCL8 activity is counteracted by chemokine cleavage, limiting its inflammatory and anti-tumoral effects. Eur J Immunol (2009) 0.97
MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. J Clin Invest (2015) 0.97
Effective treatment of therapy-resistant chronic spontaneous urticaria with omalizumab. J Allergy Clin Immunol (2010) 0.97
Mast cell-driven skin inflammation is impaired in the absence of sensory nerves. J Allergy Clin Immunol (2007) 0.96
Inflammatory murine skin responses to UV-B light are partially dependent on endothelin-1 and mast cells. Am J Pathol (2006) 0.96
Serglycin is a major proteoglycan in polarized human endothelial cells and is implicated in the secretion of the chemokine GROalpha/CXCL1. J Biol Chem (2010) 0.96
Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis. FASEB J (2008) 0.96