Published in Cell Struct Funct on December 01, 2002
Apoptosis: a review of programmed cell death. Toxicol Pathol (2007) 17.92
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J (2007) 9.65
"Sleeping beauty": quiescence in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2004) 4.23
Autophagy in chronically ischemic myocardium. Proc Natl Acad Sci U S A (2005) 3.55
The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-alpha/beta-induced ubiquitin-like protein. Proc Natl Acad Sci U S A (2004) 3.16
Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL. Cell Death Differ (2009) 2.85
Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae. Mol Biol Cell (2004) 2.84
Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors. EMBO J (2004) 2.73
Autophagic nutrient recycling in Arabidopsis directed by the ATG8 and ATG12 conjugation pathways. Plant Physiol (2005) 2.56
Salt stress-induced cell death in the unicellular green alga Micrasterias denticulata. J Exp Bot (2009) 2.39
Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochim Biophys Acta (2007) 2.08
A proteomics dissection of Arabidopsis thaliana vacuoles isolated from cell culture. Mol Cell Proteomics (2006) 2.01
Transcriptome profiling of the response of Arabidopsis suspension culture cells to Suc starvation. Plant Physiol (2004) 1.57
ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes. Nature (2015) 1.51
Proteome-wide identification of proteins and their modifications with decreased ambiguities and improved false discovery rates using unique sequence tags. Anal Chem (2008) 1.26
A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells. Oncogene (2009) 1.23
Atg19 mediates a dual interaction cargo sorting mechanism in selective autophagy. Mol Biol Cell (2006) 1.19
An autophagy-associated Atg8 protein is involved in the responses of Arabidopsis seedlings to hormonal controls and abiotic stresses. J Exp Bot (2008) 1.12
Glutathione participates in the regulation of mitophagy in yeast. J Biol Chem (2009) 1.08
Autophagy during proliferation and encystation in the protozoan parasite Entamoeba invadens. Infect Immun (2007) 1.08
Compartmentalization and molecular traffic in secondary metabolism: a new understanding of established cellular processes. Fungal Genet Biol (2010) 1.08
PpATG9 encodes a novel membrane protein that traffics to vacuolar membranes, which sequester peroxisomes during pexophagy in Pichia pastoris. Mol Biol Cell (2005) 1.03
Involvement of ROS in Curcumin-induced Autophagic Cell Death. Korean J Physiol Pharmacol (2011) 0.97
In yeast, loss of Hog1 leads to osmosensitivity of autophagy. Biochem J (2006) 0.97
No peroxisome is an island - Peroxisome contact sites. Biochim Biophys Acta (2015) 0.94
Autophagy, nutrition and immunology. Mol Aspects Med (2011) 0.94
The TOR complex 1 is distributed in endosomes and in retrograde vesicles that form from the vacuole membrane and plays an important role in the vacuole import and degradation pathway. J Biol Chem (2010) 0.94
Autophagy and cancer. Cells (2012) 0.94
Systematic cloning and analysis of autophagy-related genes from the silkworm Bombyx mori. BMC Mol Biol (2009) 0.93
Antidepressant drugs diversely affect autophagy pathways in astrocytes and neurons--dissociation from cholesterol homeostasis. Neuropsychopharmacology (2011) 0.91
New anti-proliferative agent, MK615, from Japanese apricot "Prunus mume" induces striking autophagy in colon cancer cells in vitro. World J Gastroenterol (2007) 0.89
Atg3-mediated lipidation of Atg8 is involved in encystation of Acanthamoeba. Korean J Parasitol (2011) 0.88
Dihydroartemisinin induces autophagy and inhibits the growth of iron-loaded human myeloid leukemia K562 cells via ROS toxicity. FEBS Open Bio (2012) 0.87
The vacuole import and degradation pathway utilizes early steps of endocytosis and actin polymerization to deliver cargo proteins to the vacuole for degradation. J Biol Chem (2009) 0.87
Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis. Autophagy (2013) 0.87
A selective autophagy pathway that degrades gluconeogenic enzymes during catabolite inactivation. Commun Integr Biol (2009) 0.85
Ultrastructural definition of apoptosis in heart failure. Heart Fail Rev (2008) 0.85
Induction of autophagy by second-fermentation yeasts during elaboration of sparkling wines. Appl Environ Microbiol (2006) 0.84
Autophagy in periodontitis patients and gingival fibroblasts: unraveling the link between chronic diseases and inflammation. BMC Med (2012) 0.84
Cell apoptosis, autophagy and necroptosis in osteosarcoma treatment. Oncotarget (2016) 0.81
Autophagy inhibitors as a potential antiamoebic treatment for Acanthamoeba keratitis. Antimicrob Agents Chemother (2015) 0.80
The autophagy pathway participates in resistance to tomato yellow leaf curl virus infection in whiteflies. Autophagy (2016) 0.77
Fluoxetine Decreases the Proliferation and Adipogenic Differentiation of Human Adipose-Derived Stem Cells. Int J Mol Sci (2015) 0.76
Animal genes identification and mTOR signaling reactivation in autophagy. Protein Cell (2010) 0.76
BTN1, the Saccharomyces cerevisiae homolog to the human Batten disease gene, is involved in phospholipid distribution. Dis Model Mech (2011) 0.76
Transcriptomic analysis of the autophagy machinery in crustaceans. BMC Genomics (2016) 0.75
ATG5-knockout mutants of Physcomitrella provide a platform for analyzing the involvement of autophagy in senescence processes in plant cells. Plant Signal Behav (2015) 0.75
Calcium/calmodulin-dependent protein kinase regulates the PINK1/Parkin and DJ-1 pathways of mitophagy during sepsis. FASEB J (2017) 0.75
Fluorescent markers of various organelles in the wheat pathogen Zymoseptoria tritici. Fungal Genet Biol (2017) 0.75
Ubiquitin-like Atg8 protein is expressed during autophagy and the encystation process in Naegleria gruberi. Parasitol Res (2016) 0.75
Defective expression of ATG4D abrogates autophagy and promotes growth in human uterine fibroids. Cell Death Discov (2017) 0.75
Autophagy fights disease through cellular self-digestion. Nature (2008) 33.83
Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell (2004) 21.68
Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet (2009) 14.06
Autophagy in health and disease: a double-edged sword. Science (2004) 13.69
Autophagosome formation: core machinery and adaptations. Nat Cell Biol (2007) 13.59
A unified nomenclature for yeast autophagy-related genes. Dev Cell (2003) 9.18
Eaten alive: a history of macroautophagy. Nat Cell Biol (2010) 8.83
Potential therapeutic applications of autophagy. Nat Rev Drug Discov (2007) 8.56
Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol (2009) 7.96
Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell (2009) 5.77
Protein turnover via autophagy: implications for metabolism. Annu Rev Nutr (2007) 5.75
Endoplasmic reticulum stress triggers autophagy. J Biol Chem (2006) 5.05
The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell (2004) 4.72
Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway. Dev Cell (2002) 4.49
Atg8 controls phagophore expansion during autophagosome formation. Mol Biol Cell (2008) 4.41
In search of an "autophagomometer". Autophagy (2009) 4.31
Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation. J Biol Chem (2001) 3.90
Cargo proteins facilitate the formation of transport vesicles in the cytoplasm to vacuole targeting pathway. J Biol Chem (2004) 3.86
Atg17 regulates the magnitude of the autophagic response. Mol Biol Cell (2005) 3.71
Autophagy in the eukaryotic cell. Eukaryot Cell (2002) 3.61
The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: beyond the usual suspects' review series. EMBO Rep (2008) 3.52
Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein. Cell Res (2007) 3.49
Does bafilomycin A1 block the fusion of autophagosomes with lysosomes? Autophagy (2008) 3.47
An overview of the molecular mechanism of autophagy. Curr Top Microbiol Immunol (2009) 3.29
Autophagy and human disease. Cell Cycle (2007) 3.22
A diacylglycerol-dependent signaling pathway contributes to regulation of antibacterial autophagy. Cell Host Microbe (2010) 3.18
The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae. Mol Biol Cell (2007) 3.10
SNARE proteins are required for macroautophagy. Cell (2011) 2.99
An Atg9-containing compartment that functions in the early steps of autophagosome biogenesis. J Cell Biol (2010) 2.98
Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae. Mol Biol Cell (2004) 2.84
Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy. J Biol Chem (2002) 2.80
Mitophagy in yeast occurs through a selective mechanism. J Biol Chem (2008) 2.80
The regulation of autophagy - unanswered questions. J Cell Sci (2011) 2.73
Atg11 links cargo to the vesicle-forming machinery in the cytoplasm to vacuole targeting pathway. Mol Biol Cell (2005) 2.73
Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy. Mol Biol Cell (2003) 2.72
Post-Golgi Sec proteins are required for autophagy in Saccharomyces cerevisiae. Mol Biol Cell (2010) 2.66
The molecular mechanism of autophagy. Mol Med (2003) 2.63
Eating the endoplasmic reticulum: quality control by autophagy. Trends Cell Biol (2007) 2.60
Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci U S A (2010) 2.53
Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts. Autophagy (2005) 2.52
Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy. Mol Biol Cell (2004) 2.51
Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae. Mol Biol Cell (2007) 2.45
Autophagosomes: biogenesis from scratch? Curr Opin Cell Biol (2005) 2.42
The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae. J Biol Chem (2004) 2.40
Recruitment of Atg9 to the preautophagosomal structure by Atg11 is essential for selective autophagy in budding yeast. J Cell Biol (2006) 2.35
Molecular mechanisms and regulation of specific and nonspecific autophagy pathways in yeast. J Biol Chem (2005) 2.33
Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival. J Biol Chem (2006) 2.32
The Cvt pathway as a model for selective autophagy. FEBS Lett (2010) 2.26
The scaffold protein Atg11 recruits fission machinery to drive selective mitochondria degradation by autophagy. Dev Cell (2013) 2.24
The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy. J Cell Biol (2010) 2.12
How to live long and prosper: autophagy, mitochondria, and aging. Physiology (Bethesda) (2008) 2.08
A genomic screen for yeast mutants defective in selective mitochondria autophagy. Mol Biol Cell (2009) 2.04
Mitochondria removal by autophagy. Autophagy (2011) 2.04
An overview of autophagy: morphology, mechanism, and regulation. Antioxid Redox Signal (2013) 2.04
Atg27 is required for autophagy-dependent cycling of Atg9. Mol Biol Cell (2006) 1.98
The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae. Mol Biol Cell (2005) 1.94
Atg22 recycles amino acids to link the degradative and recycling functions of autophagy. Mol Biol Cell (2006) 1.85
Yeast homotypic vacuole fusion requires the Ccz1-Mon1 complex during the tethering/docking stage. J Cell Biol (2003) 1.81
Arp2 links autophagic machinery with the actin cytoskeleton. Mol Biol Cell (2008) 1.80
Autophagic processes in yeast: mechanism, machinery and regulation. Genetics (2013) 1.78
Biochemical methods to monitor autophagy-related processes in yeast. Methods Enzymol (2008) 1.68
Vps51 is part of the yeast Vps fifty-three tethering complex essential for retrograde traffic from the early endosome and Cvt vesicle completion. J Biol Chem (2002) 1.66
Endoplasmic reticulum stress: a new pathway to induce autophagy. Autophagy (2007) 1.62
A cycling protein complex required for selective autophagy. Autophagy (2007) 1.60
Molecular machinery required for autophagy and the cytoplasm to vacuole targeting (Cvt) pathway in S. cerevisiae. Curr Opin Cell Biol (2002) 1.60
Self-interaction is critical for Atg9 transport and function at the phagophore assembly site during autophagy. Mol Biol Cell (2008) 1.58
Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos. Autophagy (2009) 1.57
Quantitative analysis of autophagy-related protein stoichiometry by fluorescence microscopy. J Cell Biol (2008) 1.55
Regulation of macroautophagy in Saccharomyces cerevisiae. Semin Cell Dev Biol (2010) 1.51
The molecular mechanism of mitochondria autophagy in yeast. Mol Microbiol (2010) 1.51
The Ccz1-Mon1 protein complex is required for the late step of multiple vacuole delivery pathways. J Biol Chem (2002) 1.50
Receptor protein complexes are in control of autophagy. Autophagy (2012) 1.49
In vivo reconstitution of autophagy in Saccharomyces cerevisiae. J Cell Biol (2008) 1.48
Increased levels of reduced cytochrome b and mitophagy components are required to trigger nonspecific autophagy following induced mitochondrial dysfunction. J Cell Sci (2012) 1.45
Autophagy in organelle homeostasis: peroxisome turnover. Mol Aspects Med (2006) 1.44
The role of autophagy in Parkinson's disease. Cold Spring Harb Perspect Med (2012) 1.44
The quantitative Pho8Delta60 assay of nonspecific autophagy. Methods Enzymol (2008) 1.44
The histone H4 lysine 16 acetyltransferase hMOF regulates the outcome of autophagy. Nature (2013) 1.43
Multiple roles of the cytoskeleton in autophagy. Biol Rev Camb Philos Soc (2009) 1.43
Atg23 is essential for the cytoplasm to vacuole targeting pathway and efficient autophagy but not pexophagy. J Biol Chem (2003) 1.39
Two MAPK-signaling pathways are required for mitophagy in Saccharomyces cerevisiae. J Cell Biol (2011) 1.37
A role for Atg8-PE deconjugation in autophagosome biogenesis. Autophagy (2012) 1.35
In the beginning there was babble... Autophagy (2012) 1.35
Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy (2005) 1.32
Roles of the lipid-binding motifs of Atg18 and Atg21 in the cytoplasm to vacuole targeting pathway and autophagy. J Biol Chem (2010) 1.28
Cell biology: regulated self-cannibalism. Nature (2004) 1.26
Positive or negative roles of different cyclin-dependent kinase Pho85-cyclin complexes orchestrate induction of autophagy in Saccharomyces cerevisiae. Mol Cell (2010) 1.23
The regulation of aging: does autophagy underlie longevity? Trends Cell Biol (2009) 1.22
Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase. Autophagy (2011) 1.20
Aspartyl aminopeptidase is imported from the cytoplasm to the vacuole by selective autophagy in Saccharomyces cerevisiae. J Biol Chem (2011) 1.17
Relieving autophagy and 4EBP1 from rapamycin resistance. Mol Cell Biol (2011) 1.16
The variability of autophagy and cell death susceptibility: Unanswered questions. Autophagy (2013) 1.15
Monitoring mitophagy in yeast: the Om45-GFP processing assay. Autophagy (2009) 1.14
Dual roles of Atg8-PE deconjugation by Atg4 in autophagy. Autophagy (2012) 1.14
Artophagy: the art of autophagy--the Cvt pathway. Autophagy (2010) 1.13
The quiz factor. CBE Life Sci Educ (2008) 1.13
Tap42-associated protein phosphatase type 2A negatively regulates induction of autophagy. Autophagy (2009) 1.12
Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation. Proc Natl Acad Sci U S A (2013) 1.10
Mitochondria autophagy in yeast. Antioxid Redox Signal (2011) 1.10
A genomic screen for yeast mutants defective in mitophagy. Autophagy (2010) 1.08